The Allele Frequency Net Database

"We want to thank all individuals who contributed to the Rare Alleles Project presented at the 15th IHWS in Brazil (September, 2008). This has now been published:

Middleton D, Gonzalez F, Fernandez-Vina M, Tiercy J-M, Marsh SGE, et al. (2009) A bioinformatics approach to ascertaining the rarity of HLA alleles. Tissue Antigens 74:480-485.

Our intention is to continue this project for the next International Workshop in Liverpool on 2012 and to work with Marcelo Fernandez-Vina and ASHI in taking this forward. Please contact us if you wish to participate."

Introduction

Allele Frequencies in Worldwide Populations

The main purpose of the allelefrequencies.net website is to provide one central source, freely available to all, for the storage of allele frequencies from different polymorphic areas in the HUMAN genome. Users can contribute the results of their work into one common database, and can perform database searches on information already available.

We have currently collected data in allele, haplotype and genotype format. The success of this website will depend on you to contribute your data.

Please cite this website using: New Allele Frequency Database: http://www.allelefrequencies.net. Middleton D, Menchaca L, Rood H, Komerofsky R. Tissue Antigens 2003, 61, 403-407.

Database information

Polymorphic Region	Population Studies	Gene/Allele Data	Haplotype Data	Genotype Data
HLA	836	821	357	-
KIR	188	188	-	104
Cytokine	113	113	-	-
MIC	57	57	-	-
Totals	1,194	1,179	357	104

The current number of Frequencies stored in our database is: 86,192 (HLA), 4,826 (KIR), 3,603 (Cytokine) and 700 (MIC) from 4,250,181 individuals.

New: We have updated the website with the new IMGT/HLA nomenclature guidelines.
IMGT/HLA last Update: 3.1.0, 16 July, 2010. | IPD-KIR last Update: 2.3.0, 16 August, 2010.