Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele at this level. If an allele has an entry with a higher resolution this will be shown at the end.

   

C*16:04

Allele reported 101 time(s) and present in 77 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
GAZGaza7.10.036042See
DEUGermany DKMS - Turkey minority0.02154856See
ITAItaly South0.0180141See
SAUSaudi Arabia pop 6 (G)0.015528927See
SDNSudan Mixed2.50.0130200See
IRNIran Tehran0.0130120See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
USAUSA NMDP Middle Eastern or North Coast of Africa0.011670890See
DEUGermany DKMS - Greece minority0.00951894See
KOSKosovo1.60.0081124See
FRAFrance Southeast1.50.0080130See
GRCGreece pop 60.0062242See
CHESwitzerland Zurich0.00614875See
GRCGreece pop 81.20.006083See
DEUGermany DKMS - Italy minority0.00561159See
CHESwitzerland Lugano0.00521169See
FRAFrance West1.00.0050100See
TUNTunisia1.00.0050100See
USAUSA Eastern European0.0050558See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00491028See
TZATanzania Maasai0.60.0047336See
CHESwitzerland Basel0.00441888See
CHESwitzerland Luzern0.00431553See
MEXMexico Mexico City Mestizo pop 20.0043234See
MLIMali Bandiagara0.0040138See
USAUSA South Texas Hispanic0.0040194See
CHESwitzerland Aargau-Solothurn0.00401838See
RUSRussia North Ossetian0.80.0039127See
DEUGermany DKMS - Croatia minority0.00392057See
DEUGermany DKMS - Romania minority0.00321234See
DEUGermany pop 80.003039689See
CMRCameroon Beti0.0030174See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
ITAItaly pop 50.0030975See
DEUGermany DKMS - Austria minority0.00241698See
CHESwitzerland Bern0.00213545See
COLColombia Bogotá Cord Blood0.40.00211463See
ITAItaly North0.0020277See
DEUGermany DKMS - France minority0.00181406See
CHESwitzerland St Gallen0.00182113See
CHNChina North Han pop 20.0018567See
CZECzech Republic NMDR0.00175099See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.40.00174335See
DEUGermany pop 60.00178862See
USAUSA NMDP African0.001528557See
DEUGermany DKMS - German donors0.00143456066See
POLPoland DKMS0.001320653See
PANPanama0.0011462See
DEUGermany DKMS - China minority0.00121282See
DEUGermany DKMS - Netherlands minority0.00111374See
TWNTaiwan Han Chinese0.0010504See
NLDNetherlands Leiden0.00101305See
USAUSA NMDP Alaska Native or Aleut0.00101376See
RUSRussia Karelia0.00091075See
DEUGermany DKMS - Spain minority0.00091107See
USAUSA Caucasian pop 40.00091070See
INDIndia Tamil Nadu0.00082492See
USAUSA Hispanic pop 20.00081999See
USAUSA NMDP Southeast Asian0.000727978See
USAUSA NMDP European Caucasian0.00061242890See
CHNChina Hubei Han0.10.00053732See
CHNChina South Han pop 20.00051098See
DEUGermany DKMS - Portugal minority0.00041176See
USAUSA NMDP Filipino0.000350614See
USAUSA NMDP South Asian Indian0.0003185391See
USAUSA NMDP Mexican or Chicano0.0003261235See
USAUSA NMDP Hispanic South or Central American0.0003146714See
USAUSA African American pop 40.00022411See
USAUSA NMDP Chinese0.000299672See
USAUSA NMDP Caribean Hispanic0.0002115374See
USAUSA NMDP North American Amerindian0.000235791See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
HKGHong Kong Chinese BMDR0.00017595See
JPNJapan pop 160.000118604See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP Caribean Black0.000033328See
USAUSA NMDP Korean0.000077584See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
UGAUganda Kampala0.0000161See
USAUSA San Antonio Caucasian0.0000222See
SENSenegal Niokholo Mandenka0.0000165See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
ITAItaly North pop 30.00.000097See
CHESwitzerland Geneva0.000080See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
CMRCameroon Bamileke0.000077See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHESwitzerland Sion0.0000832See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
ZMBZambia Lusaka0.000044See
USAUSA Asian pop 20.00001772See

See also higher resolution data of this allele


Allele  Number of Populations 
 C*16:04:01 40 
 C*16:04:01:01 

* This list corresponds to those alleles that have been reported in AFND only (i.e. only positive findings).


Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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