Allele Frequencies in World Populations

KIR Database » Linkage disequilibrium in KIR genes

 KIR gene organisation

The figures shown below present a summary of relationships between KIR genes organised by telomeric (blue) and centromeric (red) content. The aim of these figure is to describe the strongest linkage (values from 0-100%) among the different KIR genes. Gene association values are estimated usin the genotype list which is available on the website.

   
Population: 
Country:  Region:  Ethnic Origin:    

 

Total individuals analysed: 18795

 


Overall linkage


 
 CentromericTelomeric
 
 3DL3 48894954299696981009341364291100
  2DS2 3995687245454748465656584648
   2DL3 39482792918990854237428490
    2DL2 687146464849475557574749
     2DL5 7253535354488179834854
      2DS3 31312929306556623129
       2DL1 979596904136428996
        2DP1 9696904135418996
         3DP1 98914035419098
          2DL4 9341364291100
           3DL1 3531369693
            3DS1 84913641
             2DS5 873236
              2DS1 3742
               2DS4 91
                3DL2 




Both genes positive


 
 CentromericTelomeric
 3DL3 48894954299696981009341364291100
  2DS2 3846352544454748432320244348
   2DL3 39462389898989843631378290
    2DL2 362545464849442321244449
     2DL5 2852525354483935404754
      2DS3 28292929261810172629
       2DL1 959596893934408896
        2DP1 9696903934408996
         3DP1 98914035419098
          2DL4 9341364291100
           3DL1 3530369093
            3DS1 31373441
             2DS5 332936
              2DS1 3542
               2DS4 91
                3DL2 




Both genes negative



 
 CentromericTelomeric
 3DL3 000000000000000
  2DS2 14933470000334363430
   2DL3 0243200166520
    2DL2 32460000332363330
     2DL5 441100043444310
      2DS3 3200447454550
       2DL1 200122210
        2DP1 00111110
         3DP1 0000000
          2DL4 000000
           3DL1 01060
            3DS1 535310
             2DS5 5420
              2DS1 10
               2DS4 0
                3DL2 

   

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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