The Allele Frequency Net Database [KIR Linkage Disequilibrium]

KIR Database » Linkage disequilibrium in KIR genes

KIR gene organisation

The figures shown below present a summary of relationships between KIR genes organised by telomeric (blue) and centromeric (red) content. The aim of these figure is to describe the strongest linkage (values from 0-100%) among the different KIR genes. Gene association values are estimated usin the genotype list which is available on the website.

Population:

Country: Region: Ethnic Origin:

Total individuals analysed: 18992

Overall linkage


Centromeric							Telomeric

3DL3	48	89	49	54	29	96	96	98	100	93	41	36	42	91	100
	2DS2	39	95	68	72	45	45	47	48	46	56	56	58	46	48
		2DL3	39	48	27	92	91	89	89	85	42	37	42	84	89
			2DL2	68	71	46	46	48	49	47	55	57	57	47	49
				2DL5	72	54	53	53	54	48	81	78	83	48	54
					2DS3	31	31	29	30	30	64	56	62	31	29
						2DL1	97	95	96	90	41	36	42	89	96
							2DP1	96	96	90	41	35	41	89	96
								3DP1	98	91	40	35	41	90	98
									2DL4	93	41	36	42	91	100
										3DL1	35	31	36	96	93
											3DS1	84	91	36	41
												2DS5	87	32	36
													2DS1	37	42
														2DS4	91
															3DL2

Both genes positive


Centromeric							Telomeric
3DL3	48	89	49	54	29	96	96	98	100	93	41	36	42	91	100
	2DS2	38	46	35	25	44	45	47	48	43	23	20	24	43	48
		2DL3	39	46	23	89	89	89	89	84	36	31	37	82	89
			2DL2	36	25	45	46	48	49	44	23	21	24	44	49
				2DL5	28	52	52	53	54	48	39	34	40	47	54
					2DS3	28	29	29	29	26	18	10	17	26	29
						2DL1	95	95	96	89	39	34	40	88	96
							2DP1	96	96	90	39	34	40	89	96
								3DP1	98	91	40	35	41	90	98
									2DL4	93	41	36	42	91	100
										3DL1	35	30	36	90	93
											3DS1	31	37	34	41
												2DS5	32	29	36
													2DS1	35	42
														2DS4	91
															3DL2

Both genes negative


Centromeric							Telomeric
3DL3	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	2DS2	1	49	33	47	0	0	0	0	3	33	36	34	3	0
		2DL3	0	2	4	3	2	0	0	1	6	6	5	2	0
			2DL2	32	46	0	0	0	0	2	32	36	33	3	0
				2DL5	44	1	1	0	0	0	43	44	43	1	0
					2DS3	3	2	0	0	4	47	45	45	5	0
						2DL1	2	0	0	1	2	2	2	1	0
							2DP1	0	0	1	1	1	1	1	0
								3DP1	0	0	0	0	0	0	0
									2DL4	0	0	0	0	0	0
										3DL1	0	1	0	6	0
											3DS1	53	53	1	0
												2DS5	54	2	0
													2DS1	1	0
														2DS4	0
															3DL2

©2017 Allele Frequencies Website.

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.
Gonzalez-Galarza FF, Takeshita LY, Santos EJ, Kempson F, Maia MH, Silva AL, Silva AL, Ghattaoraya GS, Alfirevic A, Jones AR and Middleton D Nucleic Acid Research 2015, 39, 28, D784-8.
Liverpool, U.K.

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