Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 303 time(s) and present in 278 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BGRBulgaria Romani0.333013See
IRLIreland South44.80.2500250See
ISRIsrael Iran Jews0.21808153See
ENGEngland North West38.60.2080298See
NIRIreland Northern36.40.20201000See
ISRIsrael Morocco Jews0.197136718See
NLDNetherlands UMCU37.50.195364See
AUSAustralia New South Wales Caucasian0.1870134See
ISRIsrael Iraq Jews0.182913270See
DEUGermany DKMS - United Kingdom minority0.18031043See
NLDNetherlands Leiden0.17501305See
ISRIsrael Tunisia Jews0.17129070See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.1710146See
ZAFSouth Africa Natal Tamil0.170051See
USAUSA Caucasian pop 40.16821070See
DEUGermany DKMS - Netherlands minority0.16811374See
USAUSA Caucasian Bethesda28.70.1650307See
USAUSA NMDP European Caucasian0.16461242890See
ISRIsrael Arab pop 20.164212301See
MYSMalaysia Peninsular Indian28.80.1642271See
INDIndia South UCBB29.70.161811446See
CZECzech Republic NMDR0.16075099See
USAUSA San Francisco Caucasian0.1600220See
INDIndia Tamil Nadu0.15932492See
DEUGermany DKMS - Austria minority0.15611698See
SGPSingapore SGVP. Indian INS0.155086See
USAUSA NMDP South Asian Indian0.1545185391See
DEUGermany pop 60.15418862See
ITAItaly North pop 326.90.154097See
DEUGermany DKMS - German donors0.15373456066See
DEUGermany DKMS - Bosnia and Herzegovina minority0.15131028See
USAUSA Caucasian pop 20.1510265See
DEUGermany pop 80.150739689See
USAUSA San Antonio Caucasian0.1506222See
SDNSudan Central Shaigiya Mixed27.80.150236See
FRAFrance Southeast27.70.1500130See
INDIndia West UCBB26.80.14665829See
ISRIsrael Libya Jews0.14623739See
DEUGermany DKMS - Romania minority0.14571234See
GRCGreece pop 825.30.144683See
DEUGermany DKMS - France minority0.13761406See
POLPoland DKMS0.137720653See
USAUSA Caucasian pop 30.136088See
USAUSA NMDP Middle Eastern or North Coast of Africa0.135070890See
PAKPakistan Mixed Sindhi0.1330101See
DEUGermany DKMS - Italy minority0.13301159See
CHESwitzerland Lausanne0.1325993See
ISRIsrael USA Jews0.13136058See
FRAFrance French Bone Marrow Donor Registry0.130142623See
PRTPortugal Center0.130050See
ISRIsrael Argentina Jews0.12964307See
ISRIsrael Poland Jews0.129413871See
INDIndia Central UCBB25.90.12944204See
PAKPakistan Mixed Pathan0.1280100See
CHESwitzerland Bern0.12783545See
CZECzech Republic0.1270106See
INDIndia East UCBB23.10.12672403See
INDIndia Andhra Pradesh Golla0.1250111See
ARMArmenia combined Regions0.1250100See
HRVCroatia pop 40.12444000See
CHESwitzerland St Gallen0.12432113See
INDIndia North UCBB22.70.12345849See
INDIndia Mumbai Maratha0.123091See
DEUGermany DKMS - Croatia minority0.12132057See
ISRIsrael USSR Jews0.120545681See
CHESwitzerland Basel0.12041888See
USAUSA NMDP North American Amerindian0.120235791See
USAUSA NMDP American Indian South or Central America0.11905926See
USAUSA Philadelphia Caucasian21.50.1190141See
DEUGermany DKMS - Spain minority0.11891107See
IRNIran Tabriz Azeris0.118697See
KENKenya Nandi0.1180240See
CHESwitzerland Aargau-Solothurn0.11651838See
DEUGermany DKMS - Portugal minority0.11581176See
INDIndia North pop 20.115072See
SAUSaudi Arabia Guraiat and Hail21.60.1150213See
PRTAzores Oriental Islands0.115043See
USAUSA NMDP Southeast Asian0.114727978See
CHESwitzerland Sion0.1146832See
GRCGreece pop 60.1136242See
LKASri Lanka Colombo21.10.1130714See
TUNTunisia Gabes0.110595See
PRTPortugal Azores Terceira Island21.90.1096130See
PRTAzores Terceira Island0.1090130See
LKASri Lanka Colombo Sinhalese0.1090101See
ISRIsrael Ashkenazi Jews pop 30.10784625See
USAUSA San Diego20.00.1060496See
USAUSA NMDP Alaska Native or Aleut0.10501376See
INDIndia Delhi pop 220.00.105090See
CHESwitzerland Geneva pop 20.10481267See
DEUGermany DKMS - Greece minority0.10381894See
DEUGermany DKMS - Turkey minority0.10324856See
ITAItaly pop 50.1020975See
RUSRussia Karelia0.10141075See
CHESwitzerland Zurich0.10024875See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,18.80.09854335See
RUSRussia Bering Island Aleuts0.0962104See
TZATanzania Maasai17.90.0955336See
SWESweden Southern Sami0.0930130See
BRABrazil Mixed0.0910108See
CHNChina Shanxi HIV negative0.091022See
MEXMexico Chihuahua Chihuahua City Pop 218.20.090988See
CHESwitzerland Luzern0.09071553See
INDIndia Tamil Nadu Nadar0.090061See
IRNIran Yazd0.089356See
ISRIsrael Druze0.08865914See
MEXMexico Mexico City Mestizo population0.0874143See
MEXMexico Mestizo14.60.085041See
IRNIran Saqqez-Baneh Kurds0.083360See
IRNIran Kurd pop 20.083060See
PAKPakistan Karachi Parsi0.083091See
SWESweden Northern Sami0.0830154See
UGAUganda Kampala0.0830161See
GNBGuinea Bissau Fula0.081031See
GNBGuinea Bissau Papel0.080025See
PRTAzores Central Islands0.080059See
JORJordan Amman0.0790146See
BRABrazil Belo Horizonte Caucasian13.70.079095See
CUBCuba Caucasian15.70.079070See
ARGArgentina Rosario Toba15.10.076086See
PRTPortugal North0.076046See
AREUnited Arab Emirates Pop 10.0750570See
USAUSA North American Native0.0750187See
CHESwitzerland Lugano0.07441169See
KENKenya Luo0.0740265See
USAUSA African American Bethesda14.80.0740187See
USAUSA NMDP Mexican or Chicano0.0735261235See
USAUSA NMDP Hispanic South or Central American0.0726146714See
CHESwitzerland Graubunden0.0721759See
CUBCuba Mixed Race14.30.071042See
SGPSingapore Javaneses0.070051See
MYSMalaysia Champa13.80.069029See
ISRIsrael Bukhara Jews0.06892317See
AREUnited Arab Emirates Abu Dhabi0.067352See
GEOGeorgia Tibilisi Kurd0.067031See
USAUSA Hispanic pop 20.06701999See
USAUSA NMDP Caribean Hispanic0.0666115374See
UGAUganda Kampala pop 20.0660175See
RUSRussia Tuva pop 20.0660169See
ZAFSouth Africa Worcester13.00.0660159See
ISRIsrael Kavkazi Jews0.06352840See
PAKPakistan Brahui0.0630104See
USAUSA NMDP Caribean Indian0.063014339See
NZLNew Zealand Maori with Admixed History12.40.0620105See
CHLChile Mapuche0.061566See
COLColombia Bogotá Cord Blood12.00.06081463See
MEXMexico Mexico City Tlalpan12.10.0606330See
USAUSA Hispanic0.0600234See
USAUSA South Texas Hispanic0.0600194See
CHNChina Sichuan HIV negative0.059034See
GEOGeorgia Tibilisi0.0570109See
CHLChile Santiago Mixed11.00.056670See
GEOGeorgia Svaneti Region Svan0.056080See
USAUSA African American0.0560252See
NZLNew Zealand Polynesians with Admixed History11.10.056027See
INDIndia Northeast UCBB11.10.0557296See
CHNChina Qinghai Province Hui0.0550110See
CHNChina Inner Mongolia Region0.0540102See
PAKPakistan Burusho0.054092See
USAUSA African American pop 20.0540149See
AUSAustralia Cape York Peninsula Aborigine0.0530103See
PRTPortugal South0.051049See
USAUSA Asian pop 20.05081772See
USAUSA NMDP African0.050628557See
SDNSudan Mixed10.00.0500200See
INDIndia Khandesh Region Pawra0.050050See
NZLNew Zealand Polynesians with Full Ancestry9.50.048021See
ECUEcuador Amerindians0.047663See
USAUSA African American pop 40.04742411See
STPSao Tome Island Angolar0.047032See
USAUSA NMDP African American pop 20.0467416581See
KENKenya, Nyanza Province, Luo tribe9.00.0450100See
USAUSA NMDP Caribean Black0.044933328See
USAUSA NMDP Hawaiian or other Pacific Islander0.044711499See
NZLNew Zealand Maori with Full Ancestry8.70.044046See
BRABrazil Puyanawa8.70.0430150See
SGPSingapore SGVP Malay MAS0.042089See
ISRIsrael Georgia Jews0.04084471See
ISRIsrael Arab Druze0.0400101See
ZAFSouth Africa Natal Zulu8.00.0400100See
ISRIsrael Ethiopia Jews0.03915928See
INDIndia New Delhi0.038071See
DEUGermany DKMS - China minority0.03801282See
VNMVietnam Hanoi Kinh pop 20.0380170See
NICNicaragua Managua7.20.0374339See
MYSMalaysia Mandailing7.40.037027See
CHNChina Jiangsu Han0.03703238See
CHNChina Beijing0.037067See
MEXMexico Mexico City Mestizo pop 20.0363234See
ZMBZambia Lusaka0.035044See
CHNChina Beijing Shijiazhuang Tianjian Han0.0340618See
USAUSA NMDP Vietnamese0.033243540See
SGPSingapore Riau Malay0.0320132See
IRNIran Gorgan0.031064See
PAKPakistan Baloch0.030066See
STPSao Tome Island Forro0.030066See
SENSenegal Niokholo Mandenka0.0270165See
AUSAustralia Groote Eylandt Aborigine0.027075See
CHNChina Uyghur HIV negative0.026019See
CMRCameroon Bamileke0.026077See
IDNIndonesia Java Western5.10.0260236See
MYSMalaysia Peninsular Malay4.50.0231951See
GHAGhana Ga-Adangbe4.60.0229131See
CHNChina Hubei Han4.60.02293732See
GNBGuinea Bissau Bijago0.022023See
MEXMexico Oaxaca Zapotec0.022090See
COLColombia North Chimila Amerindians0.021247See
GNBGuinea Bissau Balanta0.021048See
USAUSA NMDP Korean0.020877584See
MYSMalaysia Patani4.00.020025See
CHNChina Marrow Donor Registry0.0200600See
ISRIsrael YemenJews0.019915542See
KORSouth Korea pop 100.01954128See
COLColombia North Wiwa El Encanto0.019252See
MEXMexico Oaxaca Mixe0.019055See
KORSouth Korea pop 30.0180485See
JPNJapan pop 50.0180117See
MYSMalaysia Kelantan3.60.018028See
MEXMexico Veracruz Xalapa3.60.017984See
CHNChina Jiangsu Province Han0.0174334See
SGPSingapore SGVP Chinese CHS0.016096See
CHNChina Yunnan Province Han0.0150101See
USAUSA Asian0.0150358See
USAUSA NMDP Chinese0.014599672See
USAUSA NMDP Filipino0.012550614See
USAUSA South Dakota Lakota Sioux0.0120302See
SGPSingapore Chinese Han0.012094See
TWNTaiwan pop 30.0120212See
CMRCameroon Beti0.0110174See
CMRCameroon Yaounde0.011092See
HKGHong Kong Chinese2.10.0110569See
VENVenezuela Perja Mountain Bari0.011055See
INDIndia West Coast Parsi0.010050See
CHNChina Guangzhou0.0100102See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
MEXMexico Mixtec0.010097See
USAUSA NMDP Japanese0.010024582See
TWNTaiwan Tzu Chi Cord Blood Bank0.0090710See
JPNJapan Central0.0090371See
HKGHong Kong Chinese cord blood registry0.00903892See
HKGHong Kong Chinese BMDR0.00847595See
AUSAustralia Yuendumu Aborigine0.0080191See
MLIMali Bandiagara0.0070138See
TWNTaiwan Tzu Chi Morrow Donor Registry0.006946682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0064233See
TWNTaiwan pop 20.0060364See
USAUSA Arizona Pima0.0060100See
CHNChina Canton Han0.0060264See
MYSMalaysia Peninsular Chinese1.00.0052194See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
USAUSA Hawaii Okinawa0.0050106See
SGPSingapore Thai0.0050100See
TWNTaiwan Minnan pop 11.00.0050102See
CHNChina South Han0.0050284See
CHNChina Guizhou Province Bouyei0.0050109See
USAUSA Arizona Gila River Amerindian0.0040492See
TWNTaiwan Han Chinese0.0040504See
USAUSA Alaska Yupik0.0040252See
JPNJapan pop 160.004018604See
ZWEZimbabwe Harare Shona0.0040230See
SGPSingapore Chinese0.70.0030149See
MEXMexico Chiapas Lacandon Mayans0.0023218See
JPNJapan pop 30.00201018See
MEXMexico Oaxaca Mixtec0.0000103See
PHLPhilippines Ivatan0.00.000050See
PAKPakistan Kalash0.000069See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
CHNChina Guizhou Province Shui0.0000153See
CHNChina Guizhou Province Miao pop 20.000085See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHNChina North Han0.0000105See
INDIndia West Bhil0.000050See
JPNJapan Hokkaido Ainu0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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