Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 56 time(s) and present in 55 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Gila River Pima0.42423000See
MEXMexico Hidalgo Mezquital Valley/ Otomi56.90.402872See
USAUSA New Mexico Canoncito Navajo0.378042See
ENGEngland Blood Donors of Mixed Ethnicity50.50.3035519See
RUSRussia Belgorod region51.00.2909153See
POLPoland BMR49.30.284823595See
RUSRussian Federation Vologda Region47.10.2815119See
USAUSA Caucasian47.40.274761655See
GRCGreece Athens54.20.27081888See
ZAFSouth Africa Caucasians0.2600102See
MEXMexico Chihuahua Tarahumara0.250044See
USAUSA San Francisco Caucasian0.2420220See
ESPSpain, Canary Islands, Gran canaria island40.50.2372215See
MEXMexico Guadalajara Mestizo pop 20.2230103See
BRABrazil Rio de Janeiro Caucasian0.2207521See
ZAFSouth African Mixed ancestry38.00.210050See
BRABrazil Barra Mansa Rio State Caucasian0.2062405See
IRNIran Baloch0.2020100See
SAUSaudi Arabia pop 6 (G)0.202028927See
NICNicaragua Mestizo (G)36.20.1940155See
CHNChina North Han0.1900105See
BRABrazil Barra Mansa Rio State Black0.184973See
RUSRussia Bashkortostan, Bashkirs30.80.1833120See
BRABrazil Rio de Janeiro Parda0.1824170See
MARMorocco Nador Metalsa pop 20.178073See
CRICosta Rica Central Valley Mestizo (G)33.10.1770221See
CRICosta Rica Guanacaste Mestizo (G)31.80.1680110See
GNBGuinea Bissau0.167065See
MARMorocco Atlantic Coast Chaouya0.162098See
MARMorocco Settat Chaouya32.40.162098See
CPVCape Verde Northwestern Islands0.149062See
MNGMongolia Buryat0.1430141See
CPVCape Verde Southeastern Islands0.121062See
INDIndia Tamil Nadu Nadar0.107061See
CHNChina Zhejiang Han0.10611734See
BRABrazil Rio de Janeiro Black0.102968See
JPNJapan Okinawa Ryukyuan0.1020143See
CRICosta Rica Amerindians (G)18.60.0930125See
CRICosta Rica African -Caribbean (G)16.60.0830102See
INDIndia Kerala Malayalam speaking13.80.0730356See
HKGHong Kong Chinese HKBMDR HLA 11 loci12.70.06535266See
ZAFSouth African Black10.60.0599142See
ZAFSouth African Indian population8.00.040050See
INDIndia Karnataka Kannada Speaking8.00.0400174See
INDIndia Andhra Pradesh Telugu Speaking6.50.0323186See
VNMVietnam Kinh6.00.0297101See
CHNChina Jingpo Minority5.80.0291105See
INDIndia Andhra Pradesh Golla0.0230111See
CHNChina Guangdong Province Meizhou Han0.0150100See
RUSRussia Nizhny Novgorod, Russians2.10.01031510See
RUSRussia Bashkortostan, Tatars1.00.0052192See
CZECzech Republic0.0050106See
KORSouth Korea pop 30.0000485See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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