Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 176 time(s) and present in 128 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Guangxi Region Maonan0.1760108See
SGPSingapore Thai0.1330100See
THAThailand Northeast0.122066See
MYSMalaysia Pahang Semai23.70.118038See
CHNChina Canton Han0.1120264See
CHNChina Southwest Dai0.1090124See
CHNChina South Han0.1080284See
THAThailand Northeast pop 20.1060400See
SGPSingapore Chinese Han0.099094See
CHNChina Guangzhou0.0980102See
MYSMalaysia Mandailing18.50.093027See
USAUSA NMDP Vietnamese0.092543540See
SGPSingapore Javaneses0.090051See
CHNChina Sichuan HIV negative0.088034See
SGPSingapore SGVP Chinese CHS0.087096See
CHNChina Yunnan Bulang0.0820116See
MYSMalaysia Patani16.00.080025See
VNMVietnam Hanoi Kinh pop 20.0790170See
HKGHong Kong Chinese14.70.0780569See
HKGHong Kong Chinese cord blood registry0.07773892See
USAUSA NMDP Chinese0.077499672See
HKGHong Kong Chinese BMDR0.07607595See
TWNTaiwan Tzu Chi Morrow Donor Registry0.073646682See
TWNTaiwan Tzu Chi Cord Blood Bank0.0730710See
MYSMalaysia Champa13.80.069029See
SGPSingapore Chinese12.80.0670149See
MYSMalaysia Peninsular Chinese12.40.0644194See
TWNTaiwan Han Chinese0.0640504See
TWNTaiwan Minnan pop 112.70.0640102See
TWNTaiwan Puyuma12.00.060050See
TWNTaiwan Siraya11.80.059051See
TWNTaiwan pop 30.0570212See
TWNTaiwan pop 20.0560364See
SGPSingapore Riau Malay0.0520132See
INDIndia West Bhil0.050050See
INDIndia Khandesh Region Pawra0.050050See
MYSMalaysia Kedah Kensiu9.50.048021See
CHNChina Marrow Donor Registry0.0450600See
TWNTaiwan Pazeh9.10.045055See
CHNChina Yunnan Hani0.0430150See
INDIndia Northeast UCBB8.40.0422296See
USAUSA Asian0.0420358See
MYSMalaysia Perak Grik Jehai0.040025See
IDNIndonesia Java Western7.20.0370236See
INDIndia Mumbai Maratha0.037091See
SGPSingapore SGVP Malay MAS0.036089See
TWNTaiwan Hakka5.50.036055See
CHNChina Hubei Han7.10.03563732See
DEUGermany DKMS - China minority0.03351282See
USAUSA NMDP Southeast Asian0.032127978See
USAUSA Asian pop 20.03161772See
CHNChina Jiangsu Province Han0.0279334See
INDIndia East UCBB5.10.02562403See
LKASri Lanka Colombo Sinhalese0.0240101See
CHNChina North Han0.0240105See
CHNChina Beijing Shijiazhuang Tianjian Han0.0240618See
CHNChina Jiangsu Han0.02303238See
CHNChina Shanxi HIV negative0.023022See
MYSMalaysia Peninsular Malay4.30.0216951See
MYSMalaysia Jelebu Temuan0.021025See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
MYSMalaysia Kedah Baling Kensiu0.020025See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0193233See
SDNSudan East Rashaida3.70.018627See
MYSMalaysia Kelantan3.60.018028See
USAUSA NMDP Filipino0.014950614See
SDNSudan Central Shaigiya Mixed2.70.013536See
INDIndia South UCBB2.50.012411446See
INDIndia Tamil Nadu0.01172492See
INDIndia West UCBB2.30.01125829See
BFABurkina Faso Rimaibe0.011047See
USAUSA NMDP South Asian Indian0.0110185391See
TWNTaiwan Saisiat2.00.010051See
CHNChina Guangdong Province Meizhou Han0.0100100See
ZAFSouth Africa Natal Tamil0.010051See
INDIndia Central UCBB2.00.00994204See
CHNChina Beijing0.008067See
PAKPakistan Baloch0.008066See
LKASri Lanka Colombo1.40.0070714See
USAUSA NMDP Hawaiian or other Pacific Islander0.006411499See
USAUSA NMDP Korean0.006377584See
SGPSingapore SGVP. Indian INS0.006086See
USAUSA San Diego1.00.0060496See
MYSMalaysia Peninsular Indian1.10.0055271See
KORSouth Korea pop 100.00554128See
INDIndia North UCBB1.00.00515849See
INDIndia Delhi pop 21.10.005090See
KORSouth Korea pop 30.0050485See
CHNChina Yunnan Province Han0.0050101See
PAKPakistan Mixed Pathan0.0050100See
TWNTaiwan Atayal0.90.0050106See
RUSRussia Tuva pop 20.0030169See
USAUSA Caucasian pop 20.0020265See
AREUnited Arab Emirates Pop 10.0020570See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA NMDP Japanese0.001424582See
NLDNetherlands Leiden0.00101305See
JPNJapan pop 30.00101018See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA Caucasian pop 40.00091070See
JPNJapan pop 160.000618604See
DEUGermany DKMS - France minority0.00041406See
DEUGermany DKMS - Italy minority0.00041159See
DEUGermany DKMS - Turkey minority0.00044856See
USAUSA NMDP Caribean Black0.000333328See
DEUGermany DKMS - Austria minority0.00031698See
USAUSA NMDP African0.000228557See
USAUSA Hispanic pop 20.00031999See
USAUSA African American pop 40.00022411See
CZECzech Republic NMDR0.00025099See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
USAUSA NMDP Hispanic South or Central American0.0002146714See
USAUSA NMDP African American pop 20.0002416581See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP Caribean Hispanic0.0001115374See
DEUGermany pop 60.00018862See
DEUGermany pop 80.000139689See
DEUGermany DKMS - German donors0.00013456066See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP North American Amerindian0.000035791See
ISRIsrael Libya Jews0.00003739See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael Iran Jews0.00008153See
ISRIsrael USSR Jews0.000045681See
ISRIsrael Iraq Jews0.000013270See
ISRIsrael Morocco Jews0.000036718See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
INDIndia West Coast Parsi0.000050See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BFABurkina Faso Fulani0.000049See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina Tibet Region Tibetan0.0000158See
NIRIreland Northern0.00.00001000See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PHLPhilippines Ivatan0.00.000050See
POLPoland DKMS0.000020653See
SCOScotland Orkney0.00.000099See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
USAUSA African American0.0000252See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Taroko0.00.000055See
TURTurkey pop 50.0000142See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Thao0.00.000030See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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