Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 247 time(s) and present in 210 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SDNSudan Central Shaigiya Mixed38.80.217736See
SDNSudan East Rashaida22.20.117927See
BFABurkina Faso Fulani0.092049See
KENKenya Nandi0.0870240See
SDNSudan Mixed13.00.0650200See
SAUSaudi Arabia Guraiat and Hail12.20.0610213See
ITAItaly North pop 311.50.058097See
ZAFSouth Africa Natal Zulu11.00.0550100See
TZATanzania Maasai10.40.0537336See
ZAFSouth Africa Worcester9.00.0500159See
GEOGeorgia Tibilisi Kurd0.050031See
CMRCameroon Baka Pygmy0.050010See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0430146See
BFABurkina Faso Rimaibe0.043047See
ISRIsrael Arab Druze0.0400101See
AREUnited Arab Emirates Abu Dhabi0.038552See
AREUnited Arab Emirates Pop 10.0380570See
CMRCameroon Sawa0.038013See
STPSao Tome Island Forro0.038066See
TURTurkey pop 50.0350142See
ISRIsrael Arab pop 20.032912301See
MNGMongolia Buryat0.0320141See
ZWEZimbabwe Harare Shona0.0310230See
PRTAzores Terceira Island0.0310130See
USAUSA African American0.0300252See
INDIndia New Delhi0.030071See
ISRIsrael Ethiopia Jews0.02955928See
PRTPortugal Azores Terceira Island4.40.0263130See
KENKenya Luo0.0260265See
BRABrazil Belo Horizonte Caucasian5.30.026095See
CMRCameroon Bamileke0.026077See
CHNChina Uyghur HIV negative0.026019See
PAKPakistan Mixed Sindhi0.0250101See
CZECzech Republic0.0240106See
CUBCuba Mixed Race4.80.024042See
ESPSpain Catalonia Girona0.023088See
ITAItaly pop 50.0230975See
ISRIsrael Bukhara Jews0.02282317See
DEUGermany DKMS - Italy minority0.02241159See
USAUSA NMDP Caribean Hispanic0.0223115374See
USAUSA NMDP Caribean Indian0.022014339See
USAUSA Spain Ancestry0.0220279See
GNBGuinea Bissau Bijago0.022023See
CMRCameroon Yaounde0.022092See
USAUSA African American pop 30.0220564See
MLIMali Bandiagara0.0220138See
UGAUganda Kampala0.0220161See
USAUSA NMDP Middle Eastern or North Coast of Africa0.021270890See
ITAItaly Bergamo4.00.0210101See
CUBCuba Caucasian4.30.021070See
USAUSA NMDP African0.020728557See
KENKenya, Nyanza Province, Luo tribe4.00.0200100See
NZLNew Zealand Maori with Admixed History3.80.0190105See
USAUSA Philadelphia Caucasian3.70.0190141See
USAUSA African American pop 40.01872411See
DEUGermany DKMS - Turkey minority0.01814856See
DEUGermany DKMS - Portugal minority0.01791176See
MEXMexico Mexico City Mestizo pop 20.0171234See
USAUSA African American pop 20.0170149See
COLColombia Bogotá Cord Blood3.10.01671463See
USAUSA NMDP Caribean Black0.016733328See
INDIndia North UCBB3.30.01635849See
USAUSA Italy Ancestry0.0160273See
FRAFrance Southeast3.10.0160130See
USAUSA Eastern European0.0160558See
STPSao Tome Island Angolar0.016032See
ISRIsrael Libya Jews0.01603739See
ISRIsrael Druze0.01565914See
GHAGhana Ga-Adangbe2.30.0153131See
BRABrazil Mixed0.0150108See
USAUSA African American Bethesda3.00.0150187See
USAUSA Hispanic0.0150234See
USAUSA NMDP African American pop 20.0149416581See
USAUSA NMDP Hispanic South or Central American0.0148146714See
USAUSA Hispanic pop 20.01481999See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.90.01454335See
USAUSA NMDP Mexican or Chicano0.0142261235See
MARMorocco Atlantic Coast Chaouya0.014098See
UGAUganda Kampala pop 20.0140175See
USAUSA Mexican American Mestizo0.0140553See
GEOGeorgia Tibilisi0.0140109See
CHNChina North Han0.0140105See
MARMorocco Settat Chaouya2.80.014098See
ISRIsrael Poland Jews0.013513871See
USAUSA San Diego2.60.0130496See
PRTAzores Oriental Islands0.013043See
DEUGermany DKMS - Spain minority0.01221107See
GRCGreece pop 82.40.012183See
USAUSA San Antonio Caucasian0.0120222See
NIRIreland Northern2.40.01201000See
INDIndia Central UCBB2.20.01114204See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
SENSenegal Niokholo Mandenka0.0110165See
PRTPortugal North0.011046See
USAUSA Caucasian pop 30.011088See
CMRCameroon Beti0.0110174See
INDIndia Delhi pop 22.20.011090See
ISRIsrael Ashkenazi Jews pop 30.01104625See
NICNicaragua Managua2.10.0105339See
ESPSpain Gipuzkoa Basque0.0100100See
GNBGuinea Bissau Balanta0.010048See
ENGEngland North West2.00.0100298See
INDIndia North pop 20.010072See
PRTPortugal Center0.010050See
PRTPortugal South0.010049See
MEXMexico Oaxaca Mixtec0.0100103See
USAUSA NMDP South Asian Indian0.0100185391See
USAUSA NMDP European Caucasian0.00971242890See
INDIndia West UCBB1.90.00945829See
FRAFrance French Bone Marrow Donor Registry0.009442623See
DEUGermany DKMS - Austria minority0.00941698See
DEUGermany pop 80.009339689See
ISRIsrael Morocco Jews0.009336718See
ISRIsrael YemenJews0.009215542See
USAUSA San Francisco Caucasian0.0090220See
USAUSA NMDP American Indian South or Central America0.00905926See
CHNChina Qinghai Province Hui0.0090110See
PRTAzores Central Islands0.009059See
DEUGermany DKMS - Greece minority0.00901894See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00881028See
USAUSA NMDP Southeast Asian0.008627978See
DEUGermany DKMS - United Kingdom minority0.00861043See
ISRIsrael Kavkazi Jews0.00832840See
ISRIsrael Tunisia Jews0.00829070See
CZECzech Republic NMDR0.00825099See
CPVCape Verde Southeastern Islands0.008062See
AUSAustralia New South Wales Caucasian0.0080134See
RUSRussia Tuva pop 20.0080169See
USAUSA Caucasian pop 20.0080265See
USAUSA South Texas Hispanic0.0080194See
ECUEcuador Amerindians0.007963See
HRVCroatia pop 40.00794000See
DEUGermany DKMS - France minority0.00791406See
USAUSA Caucasian pop 40.00751070See
MYSMalaysia Peninsular Indian1.50.0074271See
DEUGermany DKMS - Romania minority0.00731234See
USAUSA NMDP North American Amerindian0.007235791See
DEUGermany DKMS - Croatia minority0.00712057See
DEUGermany DKMS - German donors0.00703456066See
BRABrazil Puyanawa1.30.0070150See
USAUSA Caucasian Bethesda1.40.0070307See
POLPoland DKMS0.006620653See
ISRIsrael USA Jews0.00656058See
DEUGermany pop 60.00648862See
GRCGreece pop 60.0062242See
SGPSingapore SGVP. Indian INS0.006086See
SGPSingapore SGVP Malay MAS0.006089See
IRNIran Baloch0.0060100See
GEOGeorgia Svaneti Region Svan0.006080See
PAKPakistan Karachi Parsi0.006091See
PAKPakistan Brahui0.0060104See
ISRIsrael Georgia Jews0.00574471See
ISRIsrael Argentina Jews0.00574307See
INDIndia East UCBB1.10.00562403See
ISRIsrael USSR Jews0.005445681See
NLDNetherlands Leiden0.00501305See
ARMArmenia combined Regions0.0050100See
DEUGermany DKMS - Netherlands minority0.00511374See
ZAFSouth Africa Caucasians0.0050102See
USAUSA NMDP Alaska Native or Aleut0.00501376See
PAKPakistan Mixed Pathan0.0050100See
USAUSA North American Native0.0050187See
CHNChina Guangzhou0.0050102See
CHNChina Inner Mongolia Region0.0050102See
DEUGermany DKMS - China minority0.00431282See
ISRIsrael Iraq Jews0.004013270See
LKASri Lanka Colombo0.80.0040714See
IRLIreland South0.80.0040250See
THAThailand Northeast0.004066See
USAUSA Caucasian0.70.003561655See
CHNChina Jiangsu Province Han0.0035334See
MEXMexico Mexico City Mestizo population0.0035143See
INDIndia South UCBB0.70.003511446See
INDIndia Northeast UCBB0.70.0034296See
USAUSA Asian pop 20.00341772See
USAUSA NMDP Hawaiian or other Pacific Islander0.003211499See
INDIndia Tamil Nadu0.00322492See
CHNChina Jiangsu Han0.00303238See
CHNChina Hubei Han0.50.00233732See
CHNChina Marrow Donor Registry0.0020600See
TWNTaiwan pop 20.0020364See
THAThailand Northeast pop 20.0020400See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
RUSRussia Karelia0.00171075See
ISRIsrael Iran Jews0.00168153See
USAUSA NMDP Chinese0.001499672See
USAUSA NMDP Filipino0.001150614See
HKGHong Kong Chinese BMDR0.00117595See
HKGHong Kong Chinese cord blood registry0.00103892See
USAUSA Asian0.0010358See
USAUSA NMDP Vietnamese0.000943540See
KORSouth Korea pop 100.00094128See
USAUSA NMDP Korean0.000877584See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000646682See
USAUSA NMDP Japanese0.000624582See
MYSMalaysia Peninsular Malay0.10.0005951See
JPNJapan pop 160.000118604See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore SGVP Chinese CHS0.000096See
ZMBZambia Lusaka0.000044See
MARMorocco Nador Metalsa pop 20.000073See
CHNChina Beijing0.000067See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
USAUSA Alaska Yupik0.0000252See
PAKPakistan Baloch0.000066See
SGPSingapore Chinese0.00.0000149See
HKGHong Kong Chinese0.00.0000569See
MEXMexico Oaxaca Zapotec0.000090See
MEXMexico Mestizo0.00.000041See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
AUSAustralia Yuendumu Aborigine0.0000191See
KORSouth Korea pop 30.0000485See
GNBGuinea Bissau0.000065See
CPVCape Verde Northwestern Islands0.000062See
CHNChina Tibet Region Tibetan0.0000158See
GNBGuinea Bissau Fula0.000031See
GNBGuinea Bissau Papel0.000025See
TWNTaiwan Tzu Chi Cord Blood Bank0.0000710See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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