Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 240 time(s) and present in 208 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Oaxaca Mixe0.349055See
NZLNew Zealand Maori with Full Ancestry52.20.294046See
MEXMexico Oaxaca Zapotec0.261090See
NZLNew Zealand Maori with Admixed History41.00.2240105See
PAKPakistan Kalash0.216069See
MEXMexico Oaxaca Mixtec0.2160103See
JPNJapan Hokkaido Ainu0.200050See
JPNJapan Okinawa Ryukyuan0.1830143See
MEXMexico Oaxaca Jamiltepec Mixtec0.167096See
MEXMexico Mixtec0.165097See
USAUSA Alaska Yupik0.1650252See
USAUSA Hawaii Okinawa0.1430106See
MEXMexico Chiapas Lacandon Mayans0.1399218See
ASMAmerican Samoa0.130051See
MEXMexico Chihuahua Tarahumara0.125044See
TWNTaiwan Puyuma24.00.120050See
NZLNew Zealand Polynesians with Admixed History22.20.111027See
USAUSA South Dakota Lakota Sioux0.1050302See
USAUSA NMDP Alaska Native or Aleut0.10301376See
MEXMexico Mexico City Mestizo pop 20.0962234See
NZLNew Zealand Polynesians with Full Ancestry19.00.095021See
TWNTaiwan Atayal17.00.0940106See
JPNJapan pop 160.090818604See
JPNJapan pop 30.08701018See
KORSouth Korea pop 100.08664128See
USAUSA NMDP Hawaiian or other Pacific Islander0.084711499See
JPNJapan pop 50.0840117See
JPNJapan Central0.0770371See
INDIndia Delhi pop 214.40.077090See
USAUSA Arizona Pima0.0760100See
USAUSA NMDP Japanese0.074824582See
USAUSA NMDP Korean0.074777584See
TWNTaiwan Bunun13.90.0740101See
USAUSA South Texas Hispanic0.0730194See
USAUSA North American Native0.0720187See
CHNChina North Han0.0710105See
KORSouth Korea pop 30.0710485See
USAUSA Arizona Gila River Amerindian0.0690492See
RUSRussia Tuva pop 20.0690169See
MEXMexico Chichen Itza Maya (prehispanic)0.063847See
CHNChina Henan HIV negative0.063016See
CHNChina Han HIV negative0.063072See
MEXMexico Mestizo12.20.061041See
PAKPakistan Burusho0.060092See
MEXMexico Mexico City Mestizo population0.0594143See
CHNChina Yunnan Province Han0.0590101See
CHNChina Jiangsu Han0.05603238See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0558233See
TWNTaiwan Taroko10.90.055055See
DEUGermany DKMS - China minority0.05431282See
CHNChina Uyghur HIV negative0.053019See
SGPSingapore Chinese Han0.052094See
USAUSA NMDP Mexican or Chicano0.0504261235See
USAUSA Asian0.0500358See
USAUSA New Mexico Canoncito Navajo0.049042See
USAUSA Asian pop 20.04831772See
CHNChina Beijing0.048067See
CHNChina Beijing Shijiazhuang Tianjian Han0.0470618See
HKGHong Kong Chinese9.30.0470569See
VNMVietnam Hanoi Kinh pop 20.0470170See
CHNChina Guangxi Region Maonan0.0460108See
CHNChina Shanxi HIV negative0.045022See
CHNChina Sichuan HIV negative0.044034See
CHNChina Jiangsu Province Han0.0436334See
MNGMongolia Buryat0.0430141See
HKGHong Kong Chinese BMDR0.04177595See
MYSMalaysia Peninsular Chinese8.30.0412194See
USAUSA NMDP Vietnamese0.040643540See
SGPSingapore Chinese7.40.0400149See
PHLPhilippines Ivatan8.00.040050See
CHNChina Guangzhou0.0400102See
USAUSA Hispanic pop 20.03921999See
HKGHong Kong Chinese cord blood registry0.03883892See
CHNChina Canton Han0.0380264See
CHNChina Hubei Han7.50.03763732See
NICNicaragua Managua7.50.0374339See
CHNChina Marrow Donor Registry0.0360600See
TWNTaiwan Pazeh7.30.036055See
CHNChina South Han0.0350284See
IDNIndonesia Java Western6.80.0350236See
USAUSA NMDP Chinese0.034999672See
MYSMalaysia Champa6.90.034029See
TWNTaiwan Thao6.70.033030See
TWNTaiwan Tzu Chi Morrow Donor Registry0.032246682See
USAUSA Hispanic0.0320234See
PAKPakistan Mixed Sindhi0.0320101See
PAKPakistan Mixed Pathan0.0310100See
TWNTaiwan Tzu Chi Cord Blood Bank0.0310710See
TWNTaiwan Rukai6.00.030050See
INDIndia New Delhi0.030071See
INDIndia North pop 20.029072See
TWNTaiwan Paiwan5.90.029051See
TWNTaiwan Minnan pop 15.90.0290102See
INDIndia Andhra Pradesh Golla0.0280111See
USAUSA NMDP Filipino0.027850614See
USAUSA NMDP North American Amerindian0.027535791See
TWNTaiwan Han Chinese0.0270504See
TWNTaiwan Hakka5.50.027055See
INDIndia North UCBB5.30.02625849See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.026057See
TWNTaiwan pop 20.0260364See
TWNTaiwan pop 30.0240212See
LKASri Lanka Colombo Sinhalese0.0240101See
INDIndia Central UCBB4.70.02374204See
PAKPakistan Brahui0.0230104See
MEXMexico Tixcacaltuyub Maya0.022467See
GNBGuinea Bissau Bijago0.022023See
SGPSingapore SGVP Chinese CHS0.022096See
PNGPapua New Guinea Wanigela Keapara0.021066See
LKASri Lanka Colombo4.10.0210714See
MYSMalaysia Peninsular Indian4.10.0203271See
MYSMalaysia Patani4.00.020025See
MYSMalaysia Perak Grik Jehai0.020025See
SGPSingapore Javaneses0.020051See
SGPSingapore Riau Malay0.0200132See
SGPSingapore Thai0.0200100See
TWNTaiwan Saisiat3.90.020051See
TWNTaiwan Siraya3.90.020051See
USAUSA NMDP American Indian South or Central America0.02005926See
USAUSA NMDP Hispanic South or Central American0.0198146714See
INDIndia West UCBB3.90.01935829See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Southeast Asian0.018927978See
INDIndia Northeast UCBB3.70.0186296See
USAUSA San Diego3.50.0180496See
USAUSA NMDP South Asian Indian0.0175185391See
MYSMalaysia Peninsular Malay3.50.0174951See
INDIndia South UCBB3.30.016511446See
PAKPakistan Baloch0.016066See
INDIndia Tamil Nadu0.01562492See
TWNTaiwan Ami3.10.015098See
RUSRussia Bering Island Aleuts0.0144104See
INDIndia East UCBB2.80.01422403See
SWESweden Northern Sami0.0140154See
CHNChina Yunnan Hani0.0130150See
MYSMalaysia Pahang Semai2.60.013038See
SWESweden Southern Sami0.0120130See
SGPSingapore SGVP Malay MAS0.012089See
ZMBZambia Lusaka0.012044See
PAKPakistan Karachi Parsi0.011091See
IRNIran Baloch0.0110100See
AREUnited Arab Emirates Abu Dhabi0.009652See
CHNChina Southwest Dai0.0080124See
USAUSA Caucasian Bethesda1.40.0070307See
ZAFSouth Africa Worcester1.00.0060159See
SGPSingapore SGVP. Indian INS0.006086See
USAUSA San Antonio Caucasian0.0060222See
DEUGermany DKMS - Turkey minority0.00584856See
RUSRussia Karelia0.00511075See
SENSenegal Niokholo Mandenka0.0050165See
CZECzech Republic0.0050106See
ARMArmenia combined Regions0.0050100See
CHLChile Santiago Mixed1.00.005070See
PRTPortugal Azores Terceira Island0.90.0044130See
PRTAzores Terceira Island0.0040130See
USAUSA Eastern European0.0040558See
USAUSA NMDP Caribean Indian0.004014339See
AREUnited Arab Emirates Pop 10.0040570See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0040146See
GHAGhana Ga-Adangbe0.80.0038131See
USAUSA Caucasian pop 40.00371070See
USAUSA Caucasian0.70.003561655See
UGAUganda Kampala0.0030161See
NLDNetherlands Leiden0.00301305See
ITAItaly pop 50.0030975See
DEUGermany pop 60.00258862See
USAUSA NMDP Caribean Hispanic0.0024115374See
DEUGermany DKMS - France minority0.00231406See
DEUGermany DKMS - Netherlands minority0.00221374See
DEUGermany pop 80.002139689See
DEUGermany DKMS - Austria minority0.00211698See
CZECzech Republic NMDR0.00215099See
POLPoland DKMS0.002220653See
USAUSA NMDP Middle Eastern or North Coast of Africa0.002070890See
USAUSA Caucasian pop 20.0020265See
ISRIsrael Poland Jews0.001913871See
DEUGermany DKMS - German donors0.00193456066See
USAUSA NMDP European Caucasian0.00181242890See
HRVCroatia pop 40.00164000See
DEUGermany DKMS - Croatia minority0.00152057See
ISRIsrael Ashkenazi Jews pop 30.00144625See
ISRIsrael USSR Jews0.001445681See
DEUGermany DKMS - Romania minority0.00121234See
ISRIsrael USA Jews0.00126058See
ISRIsrael Argentina Jews0.00094307See
DEUGermany DKMS - United Kingdom minority0.00101043See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00084335See
USAUSA NMDP African American pop 20.0007416581See
COLColombia Bogotá Cord Blood0.10.00071463See
ISRIsrael Kavkazi Jews0.00052840See
DEUGermany DKMS - Portugal minority0.00061176See
DEUGermany DKMS - Greece minority0.00051894See
DEUGermany DKMS - Italy minority0.00041159See
USAUSA NMDP African0.000328557See
ISRIsrael Arab pop 20.000312301See
USAUSA NMDP Caribean Black0.000333328See
ISRIsrael Ethiopia Jews0.00035928See
ISRIsrael Georgia Jews0.00024471See
USAUSA African American pop 40.00022411See
ISRIsrael Tunisia Jews0.00029070See
ISRIsrael YemenJews0.000115542See
ISRIsrael Morocco Jews0.000036718See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
NIRIreland Northern0.00.00001000See
NCLNew Caledonia0.000065See
MLIMali Bandiagara0.0000138See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
GNBGuinea Bissau Balanta0.000048See
GNBGuinea Bissau Fula0.000031See
GNBGuinea Bissau Papel0.000025See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
BRABrazil Belo Horizonte Caucasian0.00.000095See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
CHNChina Tibet Region Tibetan0.0000158See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American0.0000252See
SCOScotland Orkney0.00.000099See
TURTurkey pop 50.0000142See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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