Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 165 time(s) and present in 115 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Guizhou Province Bouyei0.2270109See
CHNChina Yunnan Province Jinuo0.1880109See
CHNChina Southwest Dai0.1850124See
CHNChina Yunnan Province Han0.1830101See
CHNChina Guizhou Province Shui0.1750153See
CHNChina Guizhou Province Miao pop 20.165085See
THAThailand Northeast0.157066See
THAThailand Northeast pop 20.1440400See
TWNTaiwan pop 20.1380364See
CHNChina Guangxi Region Maonan0.1340108See
HKGHong Kong Chinese24.00.1310569See
SGPSingapore Chinese24.20.1310149See
CHNChina Hubei Han25.60.12813732See
CHNChina Marrow Donor Registry0.1240600See
SGPSingapore Thai0.1220100See
TWNTaiwan Tzu Chi Morrow Donor Registry0.117446682See
TWNTaiwan pop 30.1160212See
SGPSingapore Chinese Han0.116094See
TWNTaiwan Minnan pop 119.60.1130102See
TWNTaiwan Han Chinese0.1120504See
CHNChina Yunnan Hani0.1070150See
TWNTaiwan Tzu Chi Cord Blood Bank0.0990710See
USAUSA NMDP Chinese0.094899672See
CHNChina South Han0.0940284See
CHNChina Guangzhou0.0930102See
MYSMalaysia Kelantan17.90.089028See
CHNChina Sichuan HIV negative0.088034See
VNMVietnam Hanoi Kinh pop 20.0850170See
DEUGermany DKMS - China minority0.08271282See
CHNChina Yunnan Province Nu0.0820107See
TWNTaiwan Hakka16.40.082055See
USAUSA NMDP Vietnamese0.080043540See
CHNChina Beijing Shijiazhuang Tianjian Han0.0770618See
TWNTaiwan Siraya11.80.069051See
CHNChina Shanxi HIV negative0.068022See
CHNChina Beijing0.067067See
CHNChina Jiangsu Han0.06703238See
USAUSA Asian0.0660358See
SGPSingapore SGVP Chinese CHS0.065096See
TWNTaiwan Pazeh12.70.064055See
CHNChina Jiangsu Province Han0.0610334See
MYSMalaysia Champa10.30.052029See
USAUSA Asian pop 20.04381772See
CHNChina North Han0.0430105See
MYSMalaysia Jelebu Temuan0.042025See
MYSMalaysia Perak Grik Jehai0.040025See
JPNJapan pop 50.0400117See
CHNChina Qinghai Province Hui0.0360110See
JPNJapan pop 160.034618604See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0343233See
JPNJapan pop 30.03401018See
KORSouth Korea pop 100.03404128See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
MYSMalaysia Peninsular Chinese6.20.0309194See
KORSouth Korea pop 30.0300485See
USAUSA NMDP Korean0.027977584See
CHNChina Uyghur HIV negative0.026019See
CHNChina Inner Mongolia Region0.0250102See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
CHNChina Yunnan Province Lisu0.0220111See
JPNJapan Central0.0220371See
USAUSA NMDP Southeast Asian0.022027978See
MNGMongolia Buryat0.0210141See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
SGPSingapore Riau Malay0.0200132See
USAUSA NMDP Japanese0.020024582See
CHNChina Jingpo Minority3.90.0190105See
USAUSA NMDP Filipino0.017450614See
TWNTaiwan Thao3.30.017030See
RUSRussia Tuva pop 20.0160169See
CHNChina Tibet Region Tibetan0.0160158See
USAUSA San Diego2.90.0150496See
USAUSA Hawaii Okinawa0.0140106See
SGPSingapore SGVP Malay MAS0.012089See
SGPSingapore Javaneses0.010051See
BFABurkina Faso Fulani0.010049See
JPNJapan Hokkaido Ainu0.010050See
INDIndia Northeast UCBB1.70.0085296See
USAUSA NMDP Hawaiian or other Pacific Islander0.008311499See
AUSAustralia New South Wales Caucasian0.0080134See
CHNChina Yunnan Province Wa0.0080119See
CUBCuba Caucasian1.40.007070See
JPNJapan Okinawa Ryukyuan0.0070143See
TWNTaiwan Atayal0.90.0050106See
MYSMalaysia Peninsular Malay0.80.0042951See
CHNChina Yunnan Bulang0.0040116See
DEUGermany DKMS - Turkey minority0.00214856See
DEUGermany DKMS - Greece minority0.00161894See
ITAItaly pop 50.0010975See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA NMDP South Asian Indian0.0006185391See
RUSRussia Karelia0.00051075See
POLPoland DKMS0.000420653See
DEUGermany DKMS - Romania minority0.00041234See
DEUGermany pop 80.000439689See
DEUGermany DKMS - France minority0.00041406See
CZECzech Republic NMDR0.00045099See
COLColombia Bogotá Cord Blood0.10.00031463See
INDIndia East UCBB0.00.00022403See
DEUGermany DKMS - German donors0.00023456066See
ISRIsrael Kavkazi Jews0.00022840See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
DEUGermany pop 60.00018862See
INDIndia West UCBB0.00.00015829See
ISRIsrael USSR Jews0.000145681See
USAUSA NMDP Hispanic South or Central American0.0001146714See
INDIndia South UCBB0.00.000011446See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP North American Amerindian0.000035791See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP African American pop 20.0000416581See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
USAUSA Hispanic pop 20.00001999See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PHLPhilippines Ivatan0.00.000050See
SCOScotland Orkney0.00.000099See
SGPSingapore SGVP. Indian INS0.000086See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TURTurkey pop 50.0000142See
CUBCuba Mixed Race0.00.000042See
CZECzech Republic0.0000106See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
AUSAustralia Yuendumu Aborigine0.0000191See
BFABurkina Faso Rimaibe0.000047See
BRABrazil Belo Horizonte Caucasian0.00.000095See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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