Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 132 time(s) and present in 80 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Perja Mountain Bari0.080055See
ISRIsrael Iraq Jews0.071713270See
ISRIsrael YemenJews0.058215542See
ISRIsrael Iran Jews0.05418153See
ISRIsrael Ashkenazi Jews pop 30.02414625See
USAUSA NMDP Caribean Indian0.011014339See
USAUSA NMDP Caribean Hispanic0.0098115374See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
CPVCape Verde Southeastern Islands0.008062See
STPSao Tome Island Forro0.008066See
CUBCuba Caucasian1.40.007070See
TURTurkey pop 50.0070142See
ISRIsrael Libya Jews0.00643739See
ISRIsrael Bukhara Jews0.00622317See
ITAItaly pop 50.0060975See
ITAItaly Bergamo1.00.0060101See
ISRIsrael Tunisia Jews0.00579070See
DEUGermany DKMS - Turkey minority0.00564856See
INDIndia Delhi pop 21.10.005090See
GEOGeorgia Tibilisi0.0050109See
BRABrazil Mixed0.0050108See
ZAFSouth Africa Caucasians0.0050102See
DEUGermany DKMS - Greece minority0.00421894See
COLColombia Bogotá Cord Blood0.80.00411463See
MLIMali Bandiagara0.0040138See
AREUnited Arab Emirates Pop 10.0040570See
USAUSA Caucasian Bethesda0.80.0040307See
ISRIsrael Morocco Jews0.003836718See
USAUSA Hispanic pop 20.00351999See
DEUGermany DKMS - Italy minority0.00351159See
DEUGermany DKMS - Romania minority0.00321234See
USAUSA San Antonio Caucasian0.0030222See
RUSRussia Tuva pop 20.0030169See
ISRIsrael Arab pop 20.002812301See
ISRIsrael USSR Jews0.002845681See
ISRIsrael Poland Jews0.002813871See
ISRIsrael Ethiopia Jews0.00245928See
USAUSA NMDP Middle Eastern or North Coast of Africa0.002270890See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA San Francisco Caucasian0.0020220See
CZECzech Republic NMDR0.00195099See
USAUSA NMDP Hispanic South or Central American0.0019146714See
ISRIsrael Kavkazi Jews0.00182840See
POLPoland DKMS0.001720653See
NICNicaragua Managua0.30.0015339See
DEUGermany pop 80.001339689See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.30.00134335See
DEUGermany DKMS - Austria minority0.00121698See
DEUGermany DKMS - German donors0.00103456066See
NIRIreland Northern0.10.00101000See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA Eastern European0.0010558See
USAUSA Caucasian pop 40.00091070See
DEUGermany pop 60.00108862See
DEUGermany DKMS - Spain minority0.00091107See
ISRIsrael Argentina Jews0.00074307See
DEUGermany DKMS - Netherlands minority0.00071374See
ISRIsrael USA Jews0.00056058See
RUSRussia Karelia0.00051075See
USAUSA NMDP Mexican or Chicano0.0005261235See
ISRIsrael Druze0.00045914See
DEUGermany DKMS - France minority0.00041406See
USAUSA NMDP European Caucasian0.00041242890See
USAUSA NMDP North American Amerindian0.000335791See
DEUGermany DKMS - China minority0.00041282See
USAUSA NMDP Caribean Black0.000233328See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA NMDP African American pop 20.0002416581See
USAUSA NMDP Southeast Asian0.000127978See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP African0.000028557See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP Korean0.000077584See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American Bethesda0.00.0000187See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
USAUSA Caucasian0.00.000061655See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
ZMBZambia Lusaka0.000044See
UGAUganda Kampala0.0000161See
STPSao Tome Island Angolar0.000032See
SCOScotland Orkney0.00.000099See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
GNBGuinea Bissau0.000065See
HKGHong Kong Chinese0.00.0000569See
CZECzech Republic0.0000106See
CUBCuba Mixed Race0.00.000042See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CPVCape Verde Northwestern Islands0.000062See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
ITAItaly North pop 30.00.000097See
PHLPhilippines Ivatan0.00.000050See
MEXMexico Mestizo0.00.000041See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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