Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 197 time(s) and present in 151 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Georgia Jews0.19314471See
ISRIsrael Bukhara Jews0.13062317See
ISRIsrael Iraq Jews0.107513270See
ISRIsrael Morocco Jews0.099736718See
ISRIsrael USSR Jews0.086345681See
GEOGeorgia Tibilisi Kurd0.083031See
ISRIsrael USA Jews0.07996058See
ISRIsrael Argentina Jews0.07974307See
ISRIsrael Libya Jews0.07793739See
ISRIsrael Iran Jews0.07768153See
ISRIsrael Kavkazi Jews0.07482840See
ISRIsrael Ethiopia Jews0.07305928See
ISRIsrael Ashkenazi Jews pop 30.06804625See
ISRIsrael Tunisia Jews0.06619070See
ISRIsrael Poland Jews0.063313871See
USAUSA Spain Ancestry0.0520279See
ARMArmenia combined Regions0.0500100See
ISRIsrael Druze0.04195914See
ISRIsrael Arab pop 20.041412301See
MARMorocco Nador Metalsa pop 20.041073See
ISRIsrael YemenJews0.038015542See
DEUGermany DKMS - Turkey minority0.02824856See
PAKPakistan Karachi Parsi0.028091See
ISRIsrael Arab Druze0.0250101See
INDIndia New Delhi0.023071See
SDNSudan Mixed4.50.0230200See
INDIndia Delhi pop 24.40.022090See
INDIndia West Coast Parsi0.020050See
PRTPortugal Center0.020050See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Middle Eastern or North Coast of Africa0.017570890See
PAKPakistan Kalash0.017069See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0170146See
INDIndia Andhra Pradesh Golla0.0170111See
IRNIran Gorgan0.016064See
PAKPakistan Baloch0.016066See
IRNIran Tabriz Azeris0.015597See
ITAItaly pop 50.0150975See
AREUnited Arab Emirates Pop 10.0150570See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
GEOGeorgia Tibilisi0.0140109See
PAKPakistan Mixed Sindhi0.0130101See
INDIndia North UCBB2.50.01235849See
PRTAzores Terceira Island0.0120130See
INDIndia West UCBB2.20.01115829See
INDIndia North pop 20.010072See
PAKPakistan Mixed Pathan0.0100100See
ZAFSouth Africa Natal Tamil0.010051See
AREUnited Arab Emirates Abu Dhabi0.009652See
SAUSaudi Arabia pop 51.90.0095158See
PRTPortugal Azores Terceira Island1.80.0088130See
USAUSA NMDP South Asian Indian0.0086185391See
GRCGreece pop 60.0083242See
IRNIran Saqqez-Baneh Kurds0.008360See
INDIndia Central UCBB1.60.00814204See
USAUSA NMDP Southeast Asian0.008027978See
USAUSA South Texas Hispanic0.0080194See
IRNIran Kurd pop 20.008060See
ECUEcuador Amerindians0.007963See
MYSMalaysia Peninsular Indian1.50.0074271See
DEUGermany DKMS - Greece minority0.00711894See
MNGMongolia Buryat0.0070141See
MARMorocco Settat Chaouya1.40.007098See
MARMorocco Atlantic Coast Chaouya0.007098See
INDIndia Northeast UCBB1.40.0068296See
INDIndia East UCBB1.30.00672403See
MEXMexico Mexico City Mestizo pop 20.0064234See
DEUGermany DKMS - Romania minority0.00611234See
IRNIran Baloch0.0060100See
GEOGeorgia Svaneti Region Svan0.006080See
USAUSA Caucasian pop 20.0060265See
USAUSA Hispanic0.0060234See
USAUSA Eastern European0.0060558See
USAUSA Asian pop 20.00541772See
HRVCroatia pop 40.00514000See
CHNChina Inner Mongolia Region0.0050102See
BRABrazil Belo Horizonte Caucasian1.10.005095See
CHLChile Santiago Mixed1.00.005070See
INDIndia Tamil Nadu0.00472492See
INDIndia South UCBB0.90.004511446See
LBYLibya Cyrenaica0.0040118See
FRAFrance Southeast0.80.0040130See
USAUSA Philadelphia Caucasian0.70.0040141See
DEUGermany pop 80.003939689See
DEUGermany DKMS - Croatia minority0.00392057See
DEUGermany DKMS - Italy minority0.00391159See
DEUGermany DKMS - Austria minority0.00381698See
COLColombia Bogotá Cord Blood0.80.00381463See
DEUGermany DKMS - Spain minority0.00361107See
DEUGermany DKMS - France minority0.00361406See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.70.00364335See
POLPoland DKMS0.003420653See
CZECzech Republic NMDR0.00325099See
DEUGermany DKMS - Netherlands minority0.00331374See
DEUGermany DKMS - China minority0.00311282See
ENGEngland North West0.70.0030298See
RUSRussia Tuva pop 20.0030169See
NLDNetherlands Leiden0.00301305See
UGAUganda Kampala0.0030161See
USAUSA North American Native0.0030187See
VNMVietnam Hanoi Kinh pop 20.0030170See
KORSouth Korea pop 100.00294128See
DEUGermany DKMS - Portugal minority0.00301176See
USAUSA NMDP Korean0.002677584See
USAUSA NMDP Hispanic South or Central American0.0025146714See
USAUSA NMDP European Caucasian0.00241242890See
DEUGermany pop 60.00248862See
MYSMalaysia Peninsular Malay0.40.0021951See
FRAFrance French Bone Marrow Donor Registry0.002142623See
DEUGermany DKMS - German donors0.00203456066See
USAUSA NMDP Vietnamese0.002043540See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA Alaska Yupik0.0020252See
USAUSA San Diego0.30.0020496See
NIRIreland Northern0.30.00201000See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
CHNChina Jiangsu Han0.00203238See
CHNChina Marrow Donor Registry0.0020600See
KORSouth Korea pop 30.0020485See
USAUSA Caucasian pop 40.00191070See
USAUSA Hispanic pop 20.00181999See
CHNChina Hubei Han0.40.00173732See
USAUSA NMDP Hawaiian or other Pacific Islander0.001711499See
USAUSA NMDP Mexican or Chicano0.0016261235See
USAUSA NMDP African0.001628557See
USAUSA NMDP North American Amerindian0.001535791See
DEUGermany DKMS - United Kingdom minority0.00141043See
RUSRussia Karelia0.00141075See
USAUSA NMDP Caribean Hispanic0.0012115374See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA Mexican American Mestizo0.0010553See
TWNTaiwan Han Chinese0.0010504See
JPNJapan pop 30.00101018See
JPNJapan Central0.0010371See
USAUSA NMDP Japanese0.001024582See
JPNJapan pop 160.000918604See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
USAUSA African American pop 40.00082411See
USAUSA NMDP Chinese0.000699672See
USAUSA NMDP Caribean Black0.000433328See
USAUSA NMDP African American pop 20.0004416581See
USAUSA NMDP Filipino0.000450614See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000246682See
HKGHong Kong Chinese BMDR0.00017595See
HKGHong Kong Chinese0.00.0000569See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
CHNChina Qinghai Province Hui0.0000110See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
ITAItaly North pop 30.00.000097See
MLIMali Bandiagara0.0000138See
MEXMexico Mestizo0.00.000041See
PAKPakistan Burusho0.000092See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Asian0.0000358See
USAUSA African American0.0000252See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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