Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 117 time(s) and present in 76 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Saisiat23.50.127051See
TWNTaiwan Pazeh21.80.109055See
TWNTaiwan Ami16.30.087098See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0730233See
TWNTaiwan Puyuma14.00.070050See
TWNTaiwan Siraya13.70.069051See
CHNChina Guangxi Region Maonan0.0650108See
TWNTaiwan Tzu Chi Cord Blood Bank0.0590710See
TWNTaiwan Tzu Chi Morrow Donor Registry0.056146682See
TWNTaiwan Atayal10.40.0520106See
CHNChina Guizhou Province Shui0.0520153See
CHNChina Yunnan Province Han0.0500101See
PHLPhilippines Ivatan10.00.050050See
CHNChina Guangdong Province Meizhou Han0.0460100See
TWNTaiwan Hakka9.10.045055See
CHNChina Guizhou Province Miao pop 20.041085See
HKGHong Kong Chinese7.70.0400569See
TWNTaiwan Minnan pop 17.80.0390102See
TWNTaiwan pop 30.0380212See
SGPSingapore SGVP Chinese CHS0.038096See
HKGHong Kong Chinese BMDR0.03777595See
HKGHong Kong Chinese cord blood registry0.03723892See
CHNChina Guizhou Province Bouyei0.0360109See
VNMVietnam Hanoi Kinh pop 20.0350170See
TWNTaiwan Tao6.00.030050See
SGPSingapore Chinese6.00.0300149See
CHNChina Sichuan HIV negative0.029034See
TWNTaiwan Tsou5.90.029051See
CHNChina Southwest Dai0.0280124See
USAUSA NMDP Chinese0.026399672See
TWNTaiwan pop 20.0260364See
USAUSA NMDP Vietnamese0.024443540See
CHNChina Hubei Han4.80.02383732See
DEUGermany DKMS - China minority0.02111282See
CHNChina Beijing Shijiazhuang Tianjian Han0.0200618See
ITAItaly North pop 33.80.019097See
CHNChina Marrow Donor Registry0.0180600See
TWNTaiwan Taroko3.60.018055See
CHNChina Canton Han0.0170264See
MYSMalaysia Champa3.50.017029See
USAUSA Asian pop 20.01531772See
SGPSingapore SGVP Malay MAS0.012089See
INDIndia West Coast Parsi0.010050See
CHNChina Inner Mongolia Region0.0100102See
TWNTaiwan Bunun2.00.0100101See
CHNChina Qinghai Province Hui0.0090110See
CHNChina Yunnan Province Jinuo0.0090109See
MYSMalaysia Peninsular Chinese1.60.0077194See
USAUSA NMDP Filipino0.007250614See
CHNChina Yunnan Province Lisu0.0060111See
USAUSA NMDP Southeast Asian0.006027978See
CHNChina Jiangsu Province Han0.0053334See
FRAFrance French Bone Marrow Donor Registry0.005042623See
CHNChina Jiangsu Han0.00303238See
KORSouth Korea pop 100.00234128See
JPNJapan pop 160.002218604See
JPNJapan pop 30.00201018See
USAUSA San Diego0.30.0020496See
USAUSA NMDP Korean0.001477584See
USAUSA NMDP Hawaiian or other Pacific Islander0.001311499See
MYSMalaysia Peninsular Malay0.20.0011951See
JPNJapan Central0.0010371See
DEUGermany DKMS - Turkey minority0.00044856See
USAUSA NMDP South Asian Indian0.0001185391See
DEUGermany pop 80.000139689See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
ISRIsrael YemenJews0.000015542See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP Hispanic South or Central American0.0000146714See
ISRIsrael Poland Jews0.000013871See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP African American pop 20.0000416581See
USAUSA Hispanic pop 20.00001999See
USAUSA African American pop 40.00002411See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
POLPoland DKMS0.000020653See
SGPSingapore SGVP. Indian INS0.000086See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Tibet Region Tibetan0.0000158See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
CHNChina Yunnan Province Wa0.0000119See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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