Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 33 time(s) and present in 33 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica African -Caribbean (G)17.70.1030102See
BRABrazil Barra Mansa Rio State Black0.089073See
BRABrazil Rio de Janeiro Black0.088268See
SAUSaudi Arabia pop 515.20.0791158See
BRABrazil Rio de Janeiro Parda0.0559170See
LBYLibya Cyrenaica0.0550118See
BRABrazil Rio de Janeiro Caucasian0.0480521See
SAUSaudi Arabia pop 6 (G)0.044928927See
BRABrazil Barra Mansa Rio State Caucasian0.0407405See
ZAFSouth African Mixed ancestry8.00.040050See
ZAFSouth African Black7.70.0387142See
CRICosta Rica Guanacaste Mestizo (G)7.20.0360110See
ESPSpain, Canary Islands, Gran canaria island6.50.0349215See
NICNicaragua Mestizo (G)6.40.0320155See
GRCGreece Athens5.40.02701888See
RUSRussia Bashkortostan, Tatars5.20.0260192See
ENGEngland Blood Donors of Mixed Ethnicity4.60.0231519See
POLPoland BMR4.50.023023595See
USAUSA San Francisco Caucasian0.0230220See
RUSRussia Belgorod region4.60.0229153See
RUSRussia Nizhny Novgorod, Russians4.00.02051510See
CRICosta Rica Central Valley Mestizo (G)3.60.0180221See
RUSRussian Federation Vologda Region3.40.0168119See
RUSRussia Bashkortostan, Bashkirs3.30.0167120See
ZAFSouth African Indian population2.00.010050See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
INDIndia Kerala Malayalam speaking1.20.0060356See
INDIndia Karnataka Kannada Speaking1.10.0060174See
CRICosta Rica Amerindians (G)0.80.0040125See
INDIndia Andhra Pradesh Telugu Speaking0.50.0027186See
CHNChina Zhejiang Han0.00231734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.20.00115266See
USAUSA Arizona Gila River Pima0.00033000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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