Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 191 time(s) and present in 138 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Sarawak Bau Bidayuh0.500025See
MYSMalaysia Pahang Semai60.50.408038See
MYSMalaysia Perak Grik Jehai0.320025See
IDNIndonesia Java pop 20.264036See
MYSMalaysia Kedah Kensiu42.90.238021See
IDNIndonesia Java Western39.40.2220236See
MYSMalaysia Jelebu Temuan0.208025See
IDNIndonesia Sundanese and Javanese0.2070201See
MYSMalaysia Kedah Baling Kensiu0.200025See
MYSMalaysia Patani32.00.180025See
MYSMalaysia Kelantan28.60.179028See
SGPSingapore Javaneses0.160051See
SGPSingapore Riau Malay0.1570132See
INDIndia West Bhil0.150050See
USAUSA NMDP Filipino0.134750614See
MYSMalaysia Peninsular Malay24.00.1346951See
SGPSingapore SGVP Malay MAS0.131089See
ISRIsrael Iran Jews0.13068153See
MYSMalaysia Mandailing25.90.130027See
MYSMalaysia Champa20.70.103029See
CHNChina Yunnan Bulang0.1030116See
PHLPhilippines Ivatan18.00.090050See
USAUSA NMDP Hawaiian or other Pacific Islander0.056711499See
TWNTaiwan Tao8.00.050050See
VNMVietnam Hanoi Kinh pop 20.0440170See
SGPSingapore Thai0.0410100See
ZAFSouth African Mixed ancestry8.00.040050See
PNGPapua New Guinea East New Britain Rabaul0.038060See
INDIndia Mumbai Maratha0.037091See
USAUSA NMDP Vietnamese0.030543540See
ZAFSouth African Indian population6.00.030050See
CHNChina Jingpo Minority5.80.0290105See
CHNChina Southwest Dai0.0240124See
USAUSA Asian0.0240358See
INDIndia East UCBB4.50.02312403See
LKASri Lanka Colombo4.50.0230714See
USAUSA NMDP Southeast Asian0.022427978See
INDIndia Tamil Nadu0.01882492See
USAUSA Asian pop 20.01781772See
INDIndia West UCBB3.40.01725829See
INDIndia Delhi pop 23.30.017090See
MYSMalaysia Peninsular Indian3.30.0166271See
INDIndia Central UCBB3.10.01554204See
CHNChina Canton Han0.0150264See
INDIndia South UCBB3.00.014911446See
CHNChina South Han0.0140284See
INDIndia North UCBB2.60.01325849See
ZAFSouth Africa Worcester3.00.0130159See
USAUSA NMDP South Asian Indian0.0112185391See
INDIndia Andhra Pradesh Golla0.0110111See
MYSMalaysia Peninsular Chinese2.10.0103194See
INDIndia Northeast UCBB2.00.0101296See
INDIndia North pop 20.010072See
SGPSingapore Chinese2.00.0100149See
ZAFSouth Africa Natal Tamil0.010051See
IRNIran Yazd0.008956See
CHNChina Yunnan Province Wa0.0080119See
CHNChina Yunnan Province Lisu0.0060111See
SGPSingapore Chinese Han0.006094See
PAKPakistan Karachi Parsi0.006091See
SGPSingapore SGVP. Indian INS0.006086See
CHNChina Jiangsu Province Han0.0053334See
HKGHong Kong Chinese cord blood registry0.00513892See
HKGHong Kong Chinese1.10.0050569See
CHNChina Inner Mongolia Region0.0050102See
AREUnited Arab Emirates Pop 10.0050570See
CHNChina Marrow Donor Registry0.0050600See
CHNChina Yunnan Province Jinuo0.0050109See
TWNTaiwan Minnan pop 11.00.0050102See
PAKPakistan Mixed Pathan0.0050100See
SGPSingapore SGVP Chinese CHS0.005096See
ZAFSouth Africa Caucasians0.0050102See
TWNTaiwan pop 30.0050212See
HKGHong Kong Chinese BMDR0.00477595See
USAUSA NMDP Chinese0.004599672See
LBYLibya Cyrenaica0.0040118See
SAUSaudi Arabia pop 50.60.0032158See
CHNChina Yunnan Hani0.0030150See
CHNChina Tibet Region Tibetan0.0030158See
USAUSA North American Native0.0030187See
ISRIsrael Kavkazi Jews0.00282840See
SAUSaudi Arabia pop 6 (G)0.002428927See
CHNChina Hubei Han0.50.00233732See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0021233See
ITAItaly pop 50.0020975See
NLDNetherlands Leiden0.00201305See
CHNChina Jiangsu Han0.00203238See
USAUSA African American pop 30.0020564See
TWNTaiwan Han Chinese0.0020504See
USAUSA San Diego0.30.0020496See
TWNTaiwan Tzu Chi Morrow Donor Registry0.001846682See
DEUGermany DKMS - China minority0.00161282See
NICNicaragua Managua0.30.0015339See
ISRIsrael Iraq Jews0.001313270See
ISRIsrael Morocco Jews0.001236718See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
USAUSA NMDP Caribean Indian0.001014339See
ISRIsrael Druze0.00095914See
ISRIsrael Ashkenazi Jews pop 30.00084625See
DEUGermany DKMS - Portugal minority0.00091176See
USAUSA African American pop 40.00082411See
ISRIsrael Bukhara Jews0.00082317See
DEUGermany DKMS - Greece minority0.00081894See
DEUGermany DKMS - Netherlands minority0.00071374See
USAUSA NMDP Japanese0.000724582See
ISRIsrael USSR Jews0.000745681See
ISRIsrael Tunisia Jews0.00079070See
ISRIsrael Libya Jews0.00073739See
ISRIsrael Poland Jews0.000613871See
ISRIsrael Argentina Jews0.00064307See
ISRIsrael Georgia Jews0.00064471See
ISRIsrael YemenJews0.000615542See
DEUGermany DKMS - Turkey minority0.00064856See
USAUSA NMDP Caribean Black0.000633328See
USAUSA NMDP African American pop 20.0005416581See
USAUSA Hispanic pop 20.00051999See
DEUGermany DKMS - Croatia minority0.00052057See
USAUSA NMDP Mexican or Chicano0.0004261235See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00051028See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000470890See
ISRIsrael USA Jews0.00036058See
USAUSA NMDP African0.000328557See
HRVCroatia pop 40.00034000See
DEUGermany pop 80.000339689See
CZECzech Republic NMDR0.00035099See
USAUSA NMDP Hispanic South or Central American0.0003146714See
JPNJapan pop 160.000218604See
POLPoland DKMS0.000320653See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Caribean Hispanic0.0001115374See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
DEUGermany pop 60.00018862See
ISRIsrael Ethiopia Jews0.00015928See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael Arab pop 20.000012301See
INDIndia Khandesh Region Pawra0.000050See
INDIndia West Coast Parsi0.000050See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Qinghai Province Hui0.0000110See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
NIRIreland Northern0.00.00001000See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Kalash0.000069See
NCLNew Caledonia0.000065See
PAKPakistan Mixed Sindhi0.0000101See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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