Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 108 time(s) and present in 51 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Pahang Semai18.40.092038See
MYSMalaysia Kelantan14.30.071028See
SGPSingapore SGVP Malay MAS0.054089See
SGPSingapore Javaneses0.050051See
SGPSingapore Thai0.0410100See
SGPSingapore Riau Malay0.0400132See
MYSMalaysia Champa6.90.034029See
IDNIndonesia Java pop 20.028036See
MYSMalaysia Peninsular Malay5.50.0279951See
VNMVietnam Hanoi Kinh pop 20.0240170See
MYSMalaysia Mandailing3.70.019027See
IDNIndonesia Java Western3.40.0170236See
SGPSingapore SGVP Chinese CHS0.016096See
IDNIndonesia Sundanese and Javanese0.0150201See
USAUSA NMDP Vietnamese0.009043540See
USAUSA NMDP Filipino0.008150614See
CHNChina Guizhou Province Miao pop 20.006085See
CHNChina Guizhou Province Bouyei0.0050109See
INDIndia Delhi pop 21.10.005090See
TWNTaiwan Han Chinese0.0050504See
USAUSA NMDP Southeast Asian0.004527978See
JPNJapan Okinawa Ryukyuan0.0040143See
SGPSingapore Chinese0.70.0030149See
USAUSA Asian pop 20.00251772See
TWNTaiwan pop 30.0020212See
CHNChina South Han0.0020284See
CHNChina Canton Han0.0020264See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002046682See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Chinese0.001899672See
HKGHong Kong Chinese cord blood registry0.00123892See
USAUSA NMDP Hawaiian or other Pacific Islander0.001111499See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
CHNChina Marrow Donor Registry0.0010600See
HKGHong Kong Chinese BMDR0.00087595See
CHNChina Hubei Han0.10.00073732See
DEUGermany DKMS - China minority0.00081282See
DEUGermany DKMS - United Kingdom minority0.00051043See
INDIndia Tamil Nadu0.00032492See
SAUSaudi Arabia pop 6 (G)0.000328927See
USAUSA NMDP South Asian Indian0.0001185391See
INDIndia West UCBB0.00.00015829See
USAUSA NMDP Korean0.000177584See
INDIndia South UCBB0.00.000011446See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP European Caucasian0.00001242890See
ZAFSouth Africa Natal Zulu0.00.0000100See
SGPSingapore SGVP. Indian INS0.000086See
USAUSA Hispanic pop 20.00001999See
USAUSA African American pop 40.00002411See
HKGHong Kong Chinese0.00.0000569See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
DEUGermany pop 80.000039689See
CHNChina Guizhou Province Shui0.0000153See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
DEUGermany pop 60.00018862See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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