Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 223 time(s) and present in 160 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
POLPoland DKMS0.051820653See
RUSRussia Karelia0.04611075See
CZECzech Republic0.0420106See
CZECzech Republic NMDR0.04025099See
USAUSA San Francisco Caucasian0.0390220See
USAUSA Caucasian pop 20.0360265See
IRLIreland South7.20.0360250See
USAUSA Caucasian pop 30.034088See
ISRIsrael Tunisia Jews0.03369070See
CHESwitzerland Luzern0.03271553See
DEUGermany DKMS - Croatia minority0.03262057See
ISRIsrael USSR Jews0.032445681See
ITAItaly Bergamo5.90.0320101See
HRVCroatia pop 40.03134000See
DEUGermany DKMS - Romania minority0.02961234See
RUSRussia Bering Island Aleuts0.0288104See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02631028See
USAUSA Eastern European0.0260558See
DEUGermany DKMS - German donors0.02503456066See
DEUGermany DKMS - France minority0.02381406See
DEUGermany pop 80.023839689See
DEUGermany pop 60.02388862See
USAUSA San Diego4.50.0230496See
DEUGermany DKMS - Portugal minority0.02301176See
ISRIsrael Libya Jews0.02233739See
CHESwitzerland Bern0.02223545See
ENGEngland North West4.40.0220298See
DEUGermany DKMS - United Kingdom minority0.02161043See
USAUSA NMDP European Caucasian0.02101242890See
CHESwitzerland Zurich0.02004875See
NIRIreland Northern3.90.02001000See
CHESwitzerland Basel0.01981888See
DEUGermany DKMS - Austria minority0.01941698See
CHESwitzerland Geneva pop 20.01901267See
AUSAustralia New South Wales Caucasian0.0190134See
GEOGeorgia Svaneti Region Svan0.019080See
ITAItaly North pop 33.80.019097See
ISRIsrael Poland Jews0.018913871See
ISRIsrael USA Jews0.01866058See
PRTAzores Central Islands0.018059See
USAUSA Caucasian pop 40.01781070See
ISRIsrael Ashkenazi Jews pop 30.01764625See
ITAItaly pop 50.0170975See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0170146See
IRNIran Gorgan0.016064See
FRAFrance French Bone Marrow Donor Registry0.015542623See
CHLChile Santiago Mixed3.00.015170See
USAUSA San Antonio Caucasian0.0151222See
DEUGermany DKMS - Spain minority0.01501107See
ESPSpain Gipuzkoa Basque0.0150100See
USAUSA NMDP North American Amerindian0.014835791See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.00.01484335See
ISRIsrael Argentina Jews0.01434307See
USAUSA NMDP American Indian South or Central America0.01405926See
CHESwitzerland Lausanne0.0140993See
MARMorocco Atlantic Coast Chaouya0.014098See
MARMorocco Settat Chaouya2.80.014098See
PRTPortugal Azores Terceira Island2.60.0132130See
CHESwitzerland Sion0.0129832See
PRTAzores Terceira Island0.0120130See
UGAUganda Kampala0.0120161See
NCLNew Caledonia0.012065See
DEUGermany DKMS - Greece minority0.01181894See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
USAUSA NMDP Mexican or Chicano0.0113261235See
DEUGermany DKMS - Netherlands minority0.01131374See
SWESweden Southern Sami0.0110130See
ESPSpain Catalonia Girona0.011088See
ESPSpain Majorca and Minorca0.011090See
USAUSA Caucasian2.20.011061655See
PRTPortugal North0.011046See
USAUSA NMDP Hispanic South or Central American0.0101146714See
NLDNetherlands Leiden0.01001305See
INDIndia West Coast Parsi0.010050See
VENVenezuela Caracas Mestizo0.010050See
USAUSA African American pop 20.0100149See
FRAFrance Corsica Island0.0100100See
DEUGermany DKMS - Italy minority0.01011159See
USAUSA NMDP Middle Eastern or North Coast of Africa0.009770890See
MEXMexico Mexico City Tlalpan1.80.0091330See
COLColombia Bogotá Cord Blood1.80.00891463See
USAUSA Hispanic pop 20.00881999See
CHESwitzerland Lugano0.00801169See
FRAFrance Southeast1.50.0080130See
USAUSA South Texas Hispanic0.0080194See
ECUEcuador Amerindians0.007963See
DEUGermany DKMS - Turkey minority0.00784856See
CHLChile Mapuche0.007766See
USAUSA NMDP Caribean Hispanic0.0073115374See
USAUSA NMDP Alaska Native or Aleut0.00701376See
USAUSA South Dakota Lakota Sioux0.0070302See
USAUSA Philadelphia Caucasian1.50.0070141See
USAUSA Caucasian Bethesda1.40.0070307See
CUBCuba Caucasian1.40.007070See
MEXMexico Mexico City Mestizo pop 20.0064234See
ITAItaly North Pavia0.006081See
ESPSpain Andalusia Romani0.006099See
TUNTunisia pop 30.0060104See
USAUSA Arizona Pima0.0060100See
GRCGreece pop 81.20.006083See
SGPSingapore SGVP. Indian INS0.006086See
VENVenezuela Colonia Tovar0.005886See
BRABrazil Belo Horizonte Caucasian1.10.005095See
BRABrazil Mixed0.0050108See
MEXMexico Guadalajara Mestizo pop 20.0050103See
NZLNew Zealand Maori with Admixed History1.00.0050105See
USAUSA NMDP Caribean Indian0.005014339See
CHESwitzerland Aargau-Solothurn0.00491838See
USAUSA African American pop 40.00502411See
NICNicaragua Managua0.90.0045339See
CHESwitzerland Graubunden0.0043759See
GRCGreece pop 60.0041242See
RUSRussia Nenet Mixed0.004055See
GTMGuatemala Mayan0.0040132See
ISRIsrael Morocco Jews0.003936718See
ISRIsrael Arab pop 20.003712301See
USAUSA NMDP African American pop 20.0034416581See
RUSRussia Belgorod region0.70.0033153See
USAUSA Asian0.0030358See
RUSRussia Tuva pop 20.0030169See
CMRCameroon Beti0.0030174See
USAUSA NMDP Caribean Black0.002833328See
USAUSA NMDP African0.002328557See
ISRIsrael Druze0.00225914See
USAUSA NMDP Hawaiian or other Pacific Islander0.002011499See
USAUSA African American0.0020252See
USAUSA Alaska Yupik0.0020252See
ISRIsrael Kavkazi Jews0.00192840See
DEUGermany DKMS - China minority0.00161282See
ISRIsrael Georgia Jews0.00154471See
ISRIsrael Bukhara Jews0.00132317See
USAUSA NMDP Filipino0.001250614See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ISRIsrael Iraq Jews0.000913270See
USAUSA NMDP Japanese0.000724582See
USAUSA Asian pop 20.00061772See
INDIndia Tamil Nadu0.00042492See
USAUSA NMDP Southeast Asian0.000327978See
ISRIsrael Iran Jews0.00028153See
USAUSA NMDP Vietnamese0.000243540See
USAUSA NMDP Chinese0.000299672See
USAUSA NMDP Korean0.000177584See
HKGHong Kong Chinese cord blood registry0.00013892See
USAUSA NMDP South Asian Indian0.0001185391See
CHNChina Hubei Han0.00.00013732See
INDIndia West UCBB0.00.00015829See
HKGHong Kong Chinese BMDR0.00017595See
ISRIsrael YemenJews0.000015542See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore SGVP Chinese CHS0.000096See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHESwitzerland St Gallen0.00002113See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
CHNChina Tibet Region Tibetan0.0000158See
ITAItaly Sardinia pop30.0000100See
PAKPakistan Karachi Parsi0.000091See
PRTAzores Oriental Islands0.000043See
CMRCameroon Bamileke0.000077See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
ZMBZambia Lusaka0.000044See
AUSAustralia Yuendumu Aborigine0.0000191See
USAUSA African American Bethesda0.00.0000187See
CUBCuba Mixed Race0.00.000042See
MEXMexico Mestizo0.00.000041See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
PRTPortugal Center0.000050See
PRTPortugal South0.000049See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
HKGHong Kong Chinese0.00.0000569See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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