Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 322 time(s) and present in 302 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Taroko38.20.218055See
TWNTaiwan Bunun35.60.1930101See
JPNJapan Hokkaido Ainu0.170050See
TWNTaiwan Rukai24.00.140050See
ISRIsrael Poland Jews0.128013871See
USAUSA Hawaii Okinawa0.1240106See
ISRIsrael USA Jews0.12216058See
ISRIsrael Ashkenazi Jews pop 30.11754625See
GEOGeorgia Tibilisi Kurd0.117031See
IRNIran Yazd0.116156See
ISRIsrael Argentina Jews0.11104307See
ISRIsrael Georgia Jews0.10724471See
PAKPakistan Baloch0.103066See
GNBGuinea Bissau Papel0.100025See
PAKPakistan Burusho0.098092See
ISRIsrael USSR Jews0.097145681See
CHNChina Yunnan Province Jinuo0.0960109See
JPNJapan Okinawa Ryukyuan0.0880143See
ISRIsrael Morocco Jews0.086936718See
ISRIsrael Kavkazi Jews0.08592840See
PAKPakistan Karachi Parsi0.083091See
CHNChina Beijing0.082067See
PAKPakistan Mixed Sindhi0.0820101See
JPNJapan Central0.0810371See
PAKPakistan Brahui0.0800104See
TWNTaiwan Atayal15.10.0800106See
USAUSA NMDP Japanese0.079824582See
JPNJapan pop 30.07701018See
INDIndia New Delhi0.076071See
IRNIran Kurd pop 20.075060See
IRNIran Saqqez-Baneh Kurds0.075060See
JPNJapan pop 160.073518604See
PNGPapua New Guinea East New Britain Rabaul0.073060See
RUSRussia Bering Island Aleuts0.0721104See
ISRIsrael Iran Jews0.06978153See
ISRIsrael Druze0.06875914See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0665233See
GRCGreece pop 60.0661242See
TWNTaiwan Hakka12.70.064055See
GEOGeorgia Svaneti Region Svan0.063080See
JPNJapan pop 50.0620117See
PAKPakistan Mixed Pathan0.0610100See
AREUnited Arab Emirates Pop 10.0610570See
KORSouth Korea pop 30.0600485See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0600146See
ASMAmerican Samoa0.060051See
INDIndia North UCBB11.80.05915849See
DEUGermany DKMS - Bosnia and Herzegovina minority0.05891028See
DEUGermany DKMS - Turkey minority0.05784856See
DEUGermany DKMS - Greece minority0.05551894See
ISRIsrael Arab Druze0.0550101See
ISRIsrael Arab pop 20.054912301See
CHESwitzerland St Gallen0.05412113See
DEUGermany DKMS - Croatia minority0.05232057See
MEXMexico Chihuahua Chihuahua City Pop 210.20.051188See
USAUSA Caucasian pop 30.051088See
CZECzech Republic NMDR0.05035099See
CHNChina Yunnan Province Han0.0500101See
CHESwitzerland Lausanne0.0497993See
TWNTaiwan Saisiat9.80.049051See
TWNTaiwan Tsou9.80.049051See
CPVCape Verde Northwestern Islands0.048062See
NZLNew Zealand Polynesians with Full Ancestry9.50.048021See
RUSRussia Karelia0.04791075See
CHESwitzerland Graubunden0.0478759See
CHESwitzerland Lugano0.04751169See
HRVCroatia pop 40.04754000See
POLPoland DKMS0.047320653See
CHNChina Tibet Region Tibetan0.0470158See
IRNIran Gorgan0.047064See
ISRIsrael Tunisia Jews0.04639070See
CHESwitzerland Luzern0.04581553See
ISRIsrael Iraq Jews0.045413270See
INDIndia West UCBB9.00.04505829See
CHNChina Qinghai Province Hui0.0450110See
PRTAzores Central Islands0.045059See
IRNIran Baloch0.0450100See
RUSRussia Tuva pop 20.0450169See
USAUSA NMDP Middle Eastern or North Coast of Africa0.044270890See
CHNChina Sichuan HIV negative0.044034See
USAUSA Philadelphia Caucasian8.90.0440141See
PRTPortugal Azores Terceira Island8.80.0439130See
INDIndia Central UCBB8.80.04394204See
USAUSA NMDP Hawaiian or other Pacific Islander0.043811499See
PRTPortugal North0.043046See
SENSenegal Niokholo Mandenka0.0430165See
FRAFrance Southeast8.50.0430130See
SGPSingapore SGVP. Indian INS0.043086See
CHESwitzerland Geneva pop 20.04291267See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,8.20.04234335See
GRCGreece pop 88.40.042283See
USAUSA Caucasian pop 20.0420265See
BGRBulgaria Romani0.042013See
USAUSA NMDP South Asian Indian0.0418185391See
DEUGermany DKMS - Romania minority0.04171234See
ITAItaly pop 50.0410975See
USAUSA Eastern European0.0410558See
ARMArmenia combined Regions0.0400100See
INDIndia Andhra Pradesh Golla0.0400111See
DEUGermany DKMS - Portugal minority0.03971176See
USAUSA San Francisco Caucasian0.0390220See
USAUSA Hispanic0.0390234See
PRTAzores Terceira Island0.0390130See
TWNTaiwan Paiwan7.80.039051See
USAUSA Asian pop 20.03901772See
USAUSA NMDP Southeast Asian0.038727978See
CHESwitzerland Sion0.0387832See
KORSouth Korea pop 100.03844128See
ITAItaly North pop 37.70.038097See
DEUGermany DKMS - Italy minority0.03781159See
USAUSA NMDP Korean0.037577584See
NICNicaragua Managua6.90.0374339See
DEUGermany DKMS - Spain minority0.03751107See
NZLNew Zealand Polynesians with Admixed History7.40.037027See
BRABrazil Belo Horizonte Caucasian6.30.037095See
CHESwitzerland Bern0.03683545See
DEUGermany pop 80.036139689See
LKASri Lanka Colombo6.90.0360714See
CUBCuba Mixed Race7.10.036042See
CUBCuba Caucasian7.10.036070See
INDIndia Tamil Nadu0.03572492See
ISRIsrael Libya Jews0.03533739See
SAUSaudi Arabia Guraiat and Hail7.00.0350213See
TWNTaiwan pop 30.0350212See
JORJordan Amman0.0350146See
ISRIsrael Bukhara Jews0.03412317See
CHNChina Inner Mongolia Region0.0340102See
TWNTaiwan Minnan pop 16.90.0340102See
DEUGermany DKMS - France minority0.03381406See
DEUGermany DKMS - Austria minority0.03371698See
MYSMalaysia Peninsular Chinese6.70.0335194See
INDIndia South UCBB6.60.033111446See
USAUSA Caucasian Bethesda6.60.0330307See
GEOGeorgia Tibilisi0.0330109See
CPVCape Verde Southeastern Islands0.032062See
USAUSA Asian0.0320358See
GNBGuinea Bissau Fula0.032031See
DEUGermany DKMS - German donors0.03193456066See
SWESweden Northern Sami0.0310154See
SWESweden Southern Sami0.0310130See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
GNBGuinea Bissau0.031065See
USAUSA NMDP European Caucasian0.03091242890See
CHLChile Santiago Mixed6.00.030470See
TWNTaiwan Tzu Chi Morrow Donor Registry0.030246682See
USAUSA NMDP Caribean Hispanic0.0300115374See
IRLIreland South6.00.0300250See
SGPSingapore Javaneses0.030051See
TWNTaiwan Puyuma6.00.030050See
DEUGermany pop 60.02998862See
FRAFrance French Bone Marrow Donor Registry0.029842623See
MEXMexico Veracruz Xalapa6.00.029884See
USAUSA NMDP Hispanic South or Central American0.0295146714See
USAUSA Caucasian5.80.029461655See
INDIndia East UCBB5.80.02912403See
CHNChina Yunnan Province Wa0.0290119See
USAUSA Hispanic pop 20.02891999See
MEXMexico Mexico City Tlalpan5.80.0288330See
CZECzech Republic0.0280106See
DEUGermany DKMS - United Kingdom minority0.02801043See
MYSMalaysia Peninsular Indian5.50.0277271See
CHESwitzerland Aargau-Solothurn0.02751838See
INDIndia Northeast UCBB5.40.0270296See
CHESwitzerland Basel0.02701888See
CHNChina Jiangsu Han0.02703238See
NLDNetherlands Leiden0.02701305See
MARMorocco Atlantic Coast Chaouya0.027098See
USAUSA NMDP Caribean Indian0.027014339See
MARMorocco Settat Chaouya5.40.027098See
TWNTaiwan Pazeh5.50.027055See
CHNChina Beijing Shijiazhuang Tianjian Han0.0270618See
CHNChina Hubei Han5.30.02653732See
CHNChina Uyghur HIV negative0.026019See
USAUSA NMDP Mexican or Chicano0.0259261235See
IRNIran Tabriz Azeris0.025897See
ZAFSouth Africa Caucasians0.0250102See
TWNTaiwan Tzu Chi Cord Blood Bank0.0250710See
PNGPapua New Guinea Madang0.025065See
BRABrazil Mixed0.0250108See
CHESwitzerland Zurich0.02434875See
TWNTaiwan Han Chinese0.0240504See
USAUSA NMDP American Indian South or Central America0.02405926See
MEXMexico Guadalajara Mestizo pop 20.0240103See
MEXMexico Mestizo4.90.024041See
USAUSA African American0.0240252See
DEUGermany DKMS - China minority0.02381282See
USAUSA NMDP Chinese0.023799672See
SGPSingapore Chinese Han0.023094See
USAUSA San Diego4.50.0230496See
USAUSA NMDP Vietnamese0.022843540See
USAUSA Caucasian pop 40.02241070See
MEXMexico Tixcacaltuyub Maya0.022467See
HKGHong Kong Chinese BMDR0.02227595See
CHNChina Yunnan Province Lisu0.0220111See
AUSAustralia New South Wales Caucasian0.0220134See
CHNChina Jiangsu Province Han0.0218334See
HKGHong Kong Chinese cord blood registry0.02133892See
CHNChina Marrow Donor Registry0.0210600See
USAUSA NMDP Alaska Native or Aleut0.02101376See
VNMVietnam Hanoi Kinh pop 20.0210170See
BFABurkina Faso Rimaibe0.021047See
DEUGermany DKMS - Netherlands minority0.02081374See
COLColombia Bogotá Cord Blood4.10.02051463See
ENGEngland North West4.00.0200298See
CHNChina Southwest Dai0.0200124See
MYSMalaysia Patani4.00.020025See
ZAFSouth Africa Natal Tamil0.020051See
SGPSingapore Riau Malay0.0200132See
USAUSA African American pop 20.0200149See
CHNChina Guangzhou0.0200102See
CMRCameroon Beti0.0200174See
TWNTaiwan Siraya3.90.020051See
SGPSingapore Chinese4.00.0200149See
PRTPortugal South0.020049See
USAUSA NMDP North American Amerindian0.019935791See
COLColombia North Wiwa El Encanto0.019252See
AREUnited Arab Emirates Abu Dhabi0.019252See
MEXMexico Mexico City Mestizo pop 20.0192234See
INDIndia North pop 20.019072See
SDNSudan East Rashaida3.70.018627See
CHNChina Guizhou Province Miao pop 20.018085See
NIRIreland Northern3.40.01801000See
SDNSudan Mixed3.00.0180200See
CMRCameroon Yaounde0.017092See
INDIndia Delhi pop 22.20.017090See
HKGHong Kong Chinese3.30.0170569See
TWNTaiwan Thao3.30.017030See
PAKPakistan Kalash0.017069See
CHNChina Canton Han0.0170264See
MYSMalaysia Champa3.50.017029See
CHNChina Guizhou Province Bouyei0.0160109See
USAUSA North American Native0.0160187See
ZWEZimbabwe Harare Shona0.0160230See
CHNChina South Han0.0160284See
ECUEcuador Amerindians0.015963See
MYSMalaysia Peninsular Malay3.10.0158951See
TUNTunisia Gabes0.015795See
USAUSA NMDP Filipino0.015250614See
UGAUganda Kampala0.0150161See
USAUSA NMDP African American pop 20.0146416581See
USAUSA African American pop 40.01412411See
NZLNew Zealand Maori with Admixed History2.90.0140105See
MNGMongolia Buryat0.0140141See
USAUSA African American pop 30.0140564See
SDNSudan Central Shaigiya Mixed2.70.013536See
ZAFSouth Africa Worcester3.00.0130159See
PRTAzores Oriental Islands0.013043See
USAUSA South Texas Hispanic0.0130194See
ISRIsrael YemenJews0.013015542See
USAUSA NMDP African0.012428557See
USAUSA NMDP Caribean Black0.012333328See
ZMBZambia Lusaka0.012044See
NCLNew Caledonia0.012065See
IDNIndonesia Java Western2.10.0110236See
COLColombia North Chimila Amerindians0.010647See
MEXMexico Mexico City Mestizo population0.0105143See
TWNTaiwan pop 20.0100364See
CHNChina Guangdong Province Meizhou Han0.0100100See
ESPSpain Gipuzkoa Basque0.0100100See
CHNChina North Han0.0100105See
PRTPortugal Center0.010050See
INDIndia West Coast Parsi0.010050See
ZAFSouth Africa Natal Zulu2.00.0100100See
USAUSA San Antonio Caucasian0.0090222See
UGAUganda Kampala pop 20.0090175See
TZATanzania Maasai1.80.0090336See
STPSao Tome Island Forro0.008066See
KENKenya Nandi0.0080240See
MARMorocco Nador Metalsa pop 20.007073See
KENKenya Luo0.0060265See
CMRCameroon Bamileke0.006077See
ECUEcuador Cayapa0.0060183See
SGPSingapore SGVP Malay MAS0.006089See
SGPSingapore SGVP Chinese CHS0.005096See
PERPeru Titikaka Lake Uros0.0050105See
SGPSingapore Thai0.0050100See
USAUSA African American Bethesda1.00.0050187See
PERPeru Titikaka Lake Uro0.0050105See
RUSRussia Bashkortostan, Bashkirs0.80.0042120See
USAUSA Alaska Yupik0.0040252See
GHAGhana Ga-Adangbe0.80.0038131See
CHNChina Yunnan Hani0.0030150See
BRABrazil Puyanawa0.70.0030150See
ISRIsrael Ethiopia Jews0.00245928See
MEXMexico Chiapas Lacandon Mayans0.0023218See
THAThailand Northeast0.002066See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
BFABurkina Faso Fulani0.000049See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
AUSAustralia Yuendumu Aborigine0.0000191See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
MLIMali Bandiagara0.0000138See
TWNTaiwan Tao0.00.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Ami0.00.000098See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
STPSao Tome Island Angolar0.000032See
GNBGuinea Bissau Balanta0.000048See
GNBGuinea Bissau Bijago0.000023See
CHNChina Guizhou Province Shui0.0000153See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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