Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 38 time(s) and present in 37 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica African -Caribbean (G)21.60.1080102See
ZAFSouth African Black20.40.1021142See
USAUSA Spain Ancestry0.0610279See
BRABrazil Rio de Janeiro Black0.051568See
CHNChina Zhejiang Han0.04471734See
LBYLibya Cyrenaica0.0420118See
ZAFSouth African Mixed ancestry8.00.040050See
BRABrazil Barra Mansa Rio State Black0.034273See
USAUSA Italy Ancestry0.0290273See
NICNicaragua Mestizo (G)5.80.0290155See
CRICosta Rica Guaymi NA-DHS_10 (G)5.60.027818See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
SAUSaudi Arabia pop 6 (G)0.025728927See
RUSRussian Federation Vologda Region5.00.0252119See
RUSRussia Bashkortostan, Bashkirs5.00.0250120See
BRABrazil Barra Mansa Rio State Caucasian0.0210405See
RUSRussia Bashkortostan, Tatars3.60.0182192See
RUSRussia Nizhny Novgorod, Russians3.60.01821510See
GRCGreece Athens3.60.01801888See
CRICosta Rica Guanacaste Mestizo (G)3.60.0180110See
POLPoland BMR3.50.017723595See
USAUSA Mexican American Mestizo0.0170553See
CRICosta Rica Central Valley Mestizo (G)2.70.0160221See
HKGHong Kong Chinese HKBMDR HLA 11 loci3.20.01595266See
SAUSaudi Arabia pop 53.20.0158158See
BRABrazil Rio de Janeiro Parda0.0147170See
USAUSA San Francisco Caucasian0.0140220See
BRABrazil Rio de Janeiro Caucasian0.0134521See
RUSRussia Belgorod region2.60.0131153See
IDNIndonesia Sundanese and Javanese0.0120201See
ENGEngland Blood Donors of Mixed Ethnicity2.30.0116519See
INDIndia Kerala Malayalam speaking2.20.0110356See
INDIndia Andhra Pradesh Telugu Speaking2.20.0108186See
ESPSpain, Canary Islands, Gran canaria island1.90.0093215See
VNMVietnam Kinh1.00.0050101See
INDIndia Karnataka Kannada Speaking0.60.0030174See
USAUSA Arizona Gila River Pima0.00033000See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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