Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 229 time(s) and present in 195 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ZMBZambia Lusaka0.233044See
ISRIsrael Iran Jews0.14748153See
ZWEZimbabwe Harare Shona0.1470230See
SENSenegal Niokholo Mandenka0.1240165See
CPVCape Verde Northwestern Islands0.121062See
CMRCameroon Beti0.0950174See
USAUSA African American pop 20.0940149See
KENKenya, Nyanza Province, Luo tribe16.00.0900100See
MARMorocco Nador Metalsa pop 20.089073See
ZAFSouth Africa Natal Zulu17.00.0850100See
UGAUganda Kampala pop 20.0830175See
ISRIsrael Druze0.08095914See
CMRCameroon Sawa0.077013See
USAUSA African American Bethesda14.80.0740187See
GHAGhana Ga-Adangbe14.50.0725131See
CMRCameroon Bamileke0.071077See
USAUSA NMDP Caribean Black0.069433328See
USAUSA NMDP African American pop 20.0667416581See
USAUSA NMDP African0.065428557See
CPVCape Verde Southeastern Islands0.065062See
USAUSA African American pop 40.06222411See
CMRCameroon Yaounde0.060092See
CUBCuba Mixed Race11.90.060042See
KENKenya Luo0.0590265See
USAUSA African American pop 30.0580564See
TUNTunisia Gabes0.052695See
PRTPortugal South0.051049See
PRTAzores Oriental Islands0.051043See
CMRCameroon Baka Pygmy0.050010See
USAUSA African American0.0500252See
MEXMexico Guadalajara Mestizo pop 20.0490103See
CUBCuba Caucasian8.60.043070See
CHESwitzerland Geneva pop 20.04291267See
ISRIsrael Morocco Jews0.042036718See
MARMorocco Settat Chaouya8.20.041098See
MARMorocco Atlantic Coast Chaouya0.041098See
UGAUganda Kampala0.0400161See
PAKPakistan Baloch0.040066See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.70.03914335See
TUNTunisia pop 30.0390104See
ITAItaly North pop 37.70.038097See
ISRIsrael Argentina Jews0.03744307See
KENKenya Nandi0.0370240See
ISRIsrael USA Jews0.03616058See
MLIMali Bandiagara0.0340138See
PAKPakistan Brahui0.0340104See
USAUSA Hispanic0.0340234See
BRABrazil Belo Horizonte Caucasian6.30.032095See
USAUSA NMDP Caribean Hispanic0.0317115374See
USAUSA NMDP Caribean Indian0.031014339See
ZAFSouth Africa Worcester6.00.0310159See
GNBGuinea Bissau0.031065See
STPSao Tome Island Angolar0.031032See
ISRIsrael Bukhara Jews0.03062317See
CHLChile Santiago Mixed6.00.030470See
USAUSA South Texas Hispanic0.0300194See
USAUSA Hispanic pop 20.02811999See
SDNSudan Mixed5.50.0280200See
IRNIran Baloch0.0280100See
MEXMexico Mexico City Mestizo population0.0280143See
USAUSA NMDP Hispanic South or Central American0.0273146714See
DEUGermany DKMS - Spain minority0.02711107See
TZATanzania Maasai5.40.0269336See
AREUnited Arab Emirates Pop 10.0260570See
BRABrazil Mixed0.0250108See
COLColombia Bogotá Cord Blood4.70.02431463See
USAUSA NMDP Mexican or Chicano0.0230261235See
COLColombia North Chimila Amerindians0.021247See
GNBGuinea Bissau Balanta0.021048See
CHESwitzerland Zurich0.02094875See
GNBGuinea Bissau Papel0.020025See
ITAItaly pop 50.0200975See
PRTPortugal Center0.020050See
NICNicaragua Managua3.90.0195339See
DEUGermany DKMS - Italy minority0.01941159See
COLColombia North Wiwa El Encanto0.019252See
SAUSaudi Arabia Guraiat and Hail3.80.0190213See
USAUSA Philadelphia Caucasian3.70.0190141See
USAUSA North American Native0.0190187See
FRAFrance French Bone Marrow Donor Registry0.018042623See
ISRIsrael Ethiopia Jews0.01795928See
USAUSA Caucasian pop 30.017088See
GEOGeorgia Tibilisi Kurd0.017031See
GNBGuinea Bissau Fula0.016031See
USAUSA San Diego3.20.0160496See
USAUSA NMDP American Indian South or Central America0.01605926See
MEXMexico Mexico City Mestizo pop 20.0150234See
CHESwitzerland Lugano0.01371169See
DEUGermany DKMS - Portugal minority0.01361176See
USAUSA NMDP Middle Eastern or North Coast of Africa0.013370890See
ISRIsrael Arab pop 20.012212301See
DEUGermany DKMS - France minority0.01211406See
MKDMacedonia pop 40.0120216See
NIRIreland Northern2.30.01201000See
FRAFrance Southeast2.30.0120130See
CHESwitzerland Lausanne0.0117993See
USAUSA NMDP North American Amerindian0.011635791See
USAUSA Caucasian Bethesda2.20.0110307See
PAKPakistan Burusho0.011092See
PRTPortugal North0.011046See
AUSAustralia New South Wales Caucasian0.0110134See
CHESwitzerland Bern0.01013545See
BRABrazil Puyanawa2.00.0100150See
GEOGeorgia Tibilisi0.0100109See
ENGEngland North West2.00.0100298See
IRLIreland South2.00.0100250See
AREUnited Arab Emirates Abu Dhabi0.009652See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
PRTAzores Central Islands0.009059See
USAUSA NMDP European Caucasian0.00901242890See
GRCGreece pop 60.0083242See
PRTAzores Terceira Island0.0080130See
STPSao Tome Island Forro0.008066See
NLDNetherlands Leiden0.00801305See
ECUEcuador Amerindians0.007963See
DEUGermany DKMS - Romania minority0.00771234See
CHLChile Mapuche0.007766See
DEUGermany DKMS - United Kingdom minority0.00771043See
ISRIsrael Iraq Jews0.007513270See
ISRIsrael Ashkenazi Jews pop 30.00714625See
USAUSA San Francisco Caucasian0.0070220See
GTMGuatemala Mayan0.0070132See
MEXMexico Oaxaca Zapotec0.007090See
ISRIsrael Poland Jews0.006813871See
DEUGermany DKMS - Netherlands minority0.00621374See
ISRIsrael YemenJews0.006115542See
GRCGreece pop 81.20.006083See
USAUSA NMDP Alaska Native or Aleut0.00601376See
ITAItaly North Pavia0.006081See
USAUSA Caucasian pop 20.0060265See
USAUSA San Antonio Caucasian0.0060222See
DEUGermany pop 60.00598862See
DEUGermany DKMS - Greece minority0.00581894See
DEUGermany pop 80.005539689See
DEUGermany DKMS - Turkey minority0.00544856See
DEUGermany DKMS - German donors0.00513456066See
ZAFSouth Africa Caucasians0.0050102See
NZLNew Zealand Maori with Admixed History1.00.0050105See
USAUSA Eastern European0.0050558See
PAKPakistan Mixed Pathan0.0050100See
CHESwitzerland Luzern0.00491553See
USAUSA NMDP Hawaiian or other Pacific Islander0.004711499See
ISRIsrael Kavkazi Jews0.00442840See
PRTPortugal Azores Terceira Island0.90.0044130See
DEUGermany DKMS - Croatia minority0.00442057See
DEUGermany DKMS - Austria minority0.00411698See
SWESweden Southern Sami0.0040130See
CHNChina Beijing Shijiazhuang Tianjian Han0.0040618See
LKASri Lanka Colombo0.70.0040714See
USAUSA Caucasian pop 40.00371070See
CZECzech Republic NMDR0.00365099See
HKGHong Kong Chinese0.50.0030569See
CHESwitzerland Sion0.0029832See
ISRIsrael Tunisia Jews0.00289070See
POLPoland DKMS0.002720653See
ISRIsrael USSR Jews0.002745681See
INDIndia South UCBB0.50.002611446See
USAUSA NMDP South Asian Indian0.0024185391See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA NMDP Southeast Asian0.002327978See
HRVCroatia pop 40.00214000See
INDIndia West UCBB0.40.00195829See
USAUSA NMDP Filipino0.001450614See
INDIndia Tamil Nadu0.00142492See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00151028See
INDIndia East UCBB0.30.00132403See
USAUSA Asian0.0010358See
ISRIsrael Libya Jews0.00093739See
RUSRussia Karelia0.00091075See
INDIndia North UCBB0.20.00095849See
CHESwitzerland Graubunden0.0008759See
USAUSA NMDP Japanese0.000624582See
USAUSA Asian pop 20.00061772See
INDIndia Central UCBB0.10.00054204See
HKGHong Kong Chinese BMDR0.00057595See
ISRIsrael Georgia Jews0.00044471See
DEUGermany DKMS - China minority0.00041282See
USAUSA NMDP Chinese0.000399672See
HKGHong Kong Chinese cord blood registry0.00033892See
USAUSA NMDP Vietnamese0.000243540See
CHNChina Jiangsu Han0.00023238See
USAUSA NMDP Korean0.000177584See
KORSouth Korea pop 100.00014128See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Basel0.00001888See
CHESwitzerland Aargau-Solothurn0.00001838See
GNBGuinea Bissau Bijago0.000023See
CHNChina Tibet Region Tibetan0.0000158See
KORSouth Korea pop 30.0000485See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See
PAKPakistan Karachi Parsi0.000091See
PAKPakistan Mixed Sindhi0.0000101See
CZECzech Republic0.0000106See
USAUSA Alaska Yupik0.0000252See
PAKPakistan Kalash0.000069See
MEXMexico Oaxaca Mixtec0.0000103See
SGPSingapore Chinese0.00.0000149See
MEXMexico Mestizo0.00.000041See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional