Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 167 time(s) and present in 165 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ARGArgentina Gran Chaco Mataco Wichi61.30.386049See
ARGArgentina Gran Chaco Western Toba Pilaga60.00.300019See
ARGArgentina Gran Chaco Eastern Toba45.20.2500135See
BRABrazil Puyanawa44.00.2470150See
MEXMexico Oaxaca Mixe0.198055See
MEXMexico Chichen Itza Maya (prehispanic)0.191547See
MEXMexico Chiapas Lacandon Mayans0.1697218See
MEXMexico Tixcacaltuyub Maya0.149367See
USAUSA Arizona Gila River Amerindian0.1070492See
MEXMexico Oaxaca Jamiltepec Mixtec0.099096See
MEXMexico Mixtec0.098097See
MEXMexico Veracruz Xalapa16.70.095284See
MEXMexico Chihuahua Chihuahua City Pop 217.00.085288See
USAUSA NMDP Japanese0.084924582See
JPNJapan pop 160.084018604See
MEXMexico Mexico City Mestizo pop 20.0791234See
USAUSA NMDP North American Amerindian0.073735791See
MEXMexico Mexico City Mestizo population0.0699143See
CHESwitzerland Basel0.06751888See
NICNicaragua Managua12.90.0674339See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
CHLChile Mapuche0.061566See
SWESweden Northern Sami0.0590154See
SWESweden Southern Sami0.0580130See
CHNChina Yunnan Hani0.0570150See
KORSouth Korea pop 100.05624128See
USAUSA NMDP American Indian South or Central America0.05405926See
USAUSA NMDP Korean0.053577584See
USAUSA NMDP Mexican or Chicano0.0531261235See
CHNChina Uyghur HIV negative0.053019See
USAUSA NMDP Alaska Native or Aleut0.05201376See
MEXMexico Mexico City Tlalpan10.30.0515330See
COLColombia North Wiwa El Encanto0.048152See
USAUSA Hispanic pop 20.04791999See
USAUSA NMDP Hispanic South or Central American0.0439146714See
CHESwitzerland St Gallen0.04362113See
CHESwitzerland Geneva pop 20.04291267See
CHESwitzerland Zurich0.04274875See
CHESwitzerland Lausanne0.0403993See
COLColombia Bogotá Cord Blood7.90.03961463See
CHESwitzerland Graubunden0.0390759See
IRNIran Gorgan0.039064See
CHESwitzerland Bern0.03823545See
DEUGermany DKMS - China minority0.03811282See
CHNChina Jiangsu Province Han0.0366334See
DEUGermany DKMS - Netherlands minority0.03601374See
INDIndia Tamil Nadu0.03522492See
CHNChina Yunnan Province Han0.0350101See
ARMArmenia combined Regions0.0350100See
USAUSA San Diego6.10.0340496See
INDIndia South UCBB6.60.033211446See
USAUSA NMDP South Asian Indian0.0331185391See
NLDNetherlands Leiden0.03301305See
USAUSA Asian pop 20.03251772See
CHESwitzerland Lugano0.03201169See
CHNChina Jiangsu Han0.03073238See
AREUnited Arab Emirates Pop 10.0300570See
DEUGermany DKMS - France minority0.02991406See
ENGEngland North West5.70.0290298See
CHNChina Marrow Donor Registry0.0290600See
USAUSA NMDP Caribean Indian0.029014339See
USAUSA NMDP Caribean Hispanic0.0289115374See
DEUGermany DKMS - Austria minority0.02891698See
AREUnited Arab Emirates Abu Dhabi0.028852See
DEUGermany DKMS - Romania minority0.02881234See
CHNChina Hubei Han5.70.02843732See
TWNTaiwan Han Chinese0.0280504See
USAUSA NMDP European Caucasian0.02701242890See
IRNIran Yazd0.026856See
FRAFrance French Bone Marrow Donor Registry0.026742623See
DEUGermany DKMS - United Kingdom minority0.02641043See
ITAItaly pop 50.0260975See
USAUSA NMDP Southeast Asian0.025927978See
CHESwitzerland Sion0.0251832See
GRCGreece pop 60.0248242See
POLPoland DKMS0.024520653See
USAUSA NMDP Chinese0.024299672See
USAUSA Eastern European0.0240558See
ECUEcuador Amerindians0.023863See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,4.60.02364335See
DEUGermany DKMS - German donors0.02353456066See
HRVCroatia pop 40.02314000See
DEUGermany pop 80.023039689See
STPSao Tome Island Forro0.023066See
USAUSA San Francisco Caucasian0.0230220See
ISRIsrael Poland Jews0.022913871See
DEUGermany pop 60.02268862See
INDIndia West UCBB4.50.02235829See
LKASri Lanka Colombo4.50.0220714See
TWNTaiwan Tzu Chi Morrow Donor Registry0.021946682See
DEUGermany DKMS - Croatia minority0.02192057See
ISRIsrael Arab pop 20.021412301See
RUSRussia Karelia0.02141075See
CZECzech Republic NMDR0.02135099See
DEUGermany DKMS - Spain minority0.02081107See
USAUSA Caucasian pop 40.02061070See
MYSMalaysia Peninsular Indian4.10.0203271See
ISRIsrael Ashkenazi Jews pop 30.01994625See
INDIndia North UCBB4.00.01985849See
DEUGermany DKMS - Turkey minority0.01954856See
DEUGermany DKMS - Portugal minority0.01961176See
CHESwitzerland Aargau-Solothurn0.01941838See
INDIndia Central UCBB3.80.01904204See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Middle Eastern or North Coast of Africa0.018670890See
DEUGermany DKMS - Italy minority0.01861159See
DEUGermany DKMS - Greece minority0.01841894See
GRCGreece pop 83.60.018183See
TWNTaiwan Tzu Chi Cord Blood Bank0.0180710See
CHESwitzerland Luzern0.01761553See
MYSMalaysia Champa3.50.017029See
IRNIran Kurd pop 20.017060See
IRNIran Saqqez-Baneh Kurds0.016760See
INDIndia East UCBB3.30.01672403See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01611028See
TUNTunisia Gabes0.015795See
NLDNetherlands UMCU3.10.015664See
IRNIran Tabriz Azeris0.015597See
HKGHong Kong Chinese BMDR0.01507595See
CHNChina Sichuan HIV negative0.015034See
HKGHong Kong Chinese cord blood registry0.01463892See
TWNTaiwan pop 30.0140212See
USAUSA NMDP Vietnamese0.013743540See
PRTPortugal Azores Terceira Island2.60.0132130See
THAThailand Northeast pop 20.0130400See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0129233See
MYSMalaysia Peninsular Chinese2.60.0129194See
ISRIsrael Tunisia Jews0.01219070See
SGPSingapore SGVP. Indian INS0.012086See
ISRIsrael Iraq Jews0.011813270See
ISRIsrael Bukhara Jews0.01102317See
SGPSingapore SGVP Chinese CHS0.011096See
USAUSA NMDP Hawaiian or other Pacific Islander0.010911499See
COLColombia North Chimila Amerindians0.010647See
USAUSA African American pop 40.01042411See
INDIndia Northeast UCBB2.00.0101296See
USAUSA NMDP African American pop 20.0100416581See
RUSRussia Bering Island Aleuts0.0096104See
USAUSA NMDP Caribean Black0.009433328See
UGAUganda Kampala pop 20.0090175See
TWNTaiwan pop 20.0080364See
CHNChina Southwest Dai0.0080124See
USAUSA NMDP African0.007928557See
ISRIsrael YemenJews0.007815542See
ISRIsrael Iran Jews0.00748153See
ISRIsrael Libya Jews0.00733739See
USAUSA NMDP Filipino0.005950614See
ISRIsrael USSR Jews0.005745681See
ISRIsrael Argentina Jews0.00504307See
NZLNew Zealand Maori with Admixed History1.00.0050105See
PERPeru Titikaka Lake Uros0.0050105See
ISRIsrael Georgia Jews0.00464471See
MYSMalaysia Peninsular Malay0.80.0042951See
CHNChina Yunnan Bulang0.0040116See
GHAGhana Ga-Adangbe0.80.0038131See
ISRIsrael USA Jews0.00366058See
ISRIsrael Kavkazi Jews0.00232840See
ISRIsrael Morocco Jews0.002236718See
ISRIsrael Druze0.00155914See
ISRIsrael Ethiopia Jews0.00015928See
SGPSingapore SGVP Malay MAS0.000089See
STPSao Tome Island Angolar0.000032See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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