Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 325 time(s) and present in 222 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Sabah Kadazan0.246057See
PHLPhilippines National Capital Region0.167051See
MYSMalaysia Sarawak Iban0.157051See
MYSMalaysia Sarawak Bidayuh0.140050See
MYSMalaysia Perak Rawa0.090023See
ISRIsrael Jews pop 20.20.088023000See
BFABurkina Faso Mossi0.075053See
CHNChina Yunnan Province Han pop 20.0740129See
ZAFSouth Africa Tswana14.60.073041See
TWNTaiwan Aborigine0.0630111See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.059094See
MYSMalaysia pop 30.05901445See
MYSMalaysia pop 20.057062See
ZAFSouth Africa Natal Zulu11.00.0550100See
CMRCameroon Bamileke 20.043035See
BFABurkina Faso Rimaibe0.043047See
BFABurkina Faso Fulani0.041049See
USAUSA OPTN African American0.03701510See
CMRCameroon Podokwo0.035043See
MEXMexico Jalisco, Tlajomulco0.033330See
THAThailand Northeast0.031066See
SAUSaudi Arabia5.60.028418See
USAUSA OPTN Asian0.0260261See
INDIndia Jalpaiguri Toto5.00.025340See
THAThailand Northeast pop 20.0250400See
CUBCuba Mixed Race4.80.024042See
MEXMexico Veracruz, Poza Rica0.022245See
GHAGhana Accre Asutuare Akan0.0220429See
COLColombia Barranquilla0.0215188See
MEXMexico Baja California, La Paz0.020075See
BRABrazil Sao Paulo Mixed0.40.0200239See
MEXMexico Puebla Mestizo0.020099See
MEXMexico Morelos Rural0.016730See
MMRMyanmar Mon3.10.015664See
DZAAlgeria pop 23.00.0151106See
CUBCuba Mixed pop 20.0150189See
BRABrazil REDOME Bahia0.014547399See
MARMorocco pop 20.0140110See
BRABrazil Rio Grande do Sul Black0.0140248See
MEXMexico Coahuila, Saltillo0.013772See
BRABrazil Rio Grande do Sul Mixed0.0130324See
ESPSpain North Cabuerniga0.013095See
ECUEcuador Amazonia Mixed Ancestry0.012839See
BRABrazil Minas Gerais State Mixed2.30.01201000See
BRABrazil REDOME Maranhao0.011910180See
BRABrazil Para Cord Blood Unit2.30.0113841See
BRABrazil REDOME Acre0.0111859See
AUSAustralia West Caucasian2.20.0110891See
MMRMyanmar Bamar2.20.010946See
BRABrazil REDOME Amapa0.010717864See
BRABrazil REDOME Sergipe0.01057321See
BRABrazil REDOME Rio de Janeiro0.0103139322See
BRABrazil REDOME Piaui0.010146140See
BRABrazil REDOME Tocantins0.010120692See
IRQIraq Arabs2.00.0101149See
MEXMexico Quintana Roo Rural0.010050See
BRABrazil REDOME Espirito Santo0.010088485See
BRABrazil REDOME Minas Gerais0.0100211275See
BRABrazil Rio Grande do Norte Mestizo0.010012973See
BRABrazil Piaui Mixed0.010021943See
TTOTrinidad African0.010067See
VENVenezuela Caracas Mestizo0.010050See
FRAFrance Corsica Island0.0100100See
MYSMalaysia Negeri Sembilan Minangkabau0.010034See
VNMVietnam Hanoi0.010050See
MARMorocco Casablanca0.0100100See
BRABrazil REDOME Alagoas0.009825349See
BRABrazil Para State1.00.00985000See
MEXMexico Sinaloa, Culiacán0.0097103See
MEXMexico Zacatecas, Fresnillo0.0095103See
BRABrazil REDOME Pernambuco0.009592332See
BRABrazil REDOME Rondonia0.009454396See
MMRMyanmar Shan1.90.009354See
PRTMadeira pop 20.0090173See
THAThailand pop 40.009016807See
PRTPortugal Viana do Castelo0.0090706See
ARGArgentina La Plata2.00.0090100See
BRABrazil REDOME Ceara0.0089101217See
BRABrazil REDOME Goias0.008988574See
BRABrazil REDOME Federal District0.008829549See
BRABrazil REDOME Rio Grande do Norte0.008746603See
MEXMexico Veracruz, Veracruz city0.0087171See
BRABrazil REDOME Paraiba0.008543868See
BRABrazil REDOME Para0.008472637See
BRABrazil South East Cord Blood0.008311409See
BRABrazil REDOME Mato Grosso0.008234649See
PRTPortugal Guarda0.0080797See
BRABrazil South Ribeirao Preto0.0080184See
CUBCuba Mixed0.008078See
GTMGuatemala, Guatemala City Mixed Ancestry1.60.0079127See
BRABrazil REDOME Amazonas0.007524129See
BRABrazil REDOME Mato Grosso do Sul0.007495667See
BRABrazil REDOME Sao Paulo0.0072800809See
PRTMadeira pop 30.0070538See
ESPSpain Arratia Valley Basque0.007083See
CZECzech Republic Kurd1.40.006874See
MEXMexico Oaxaca, Oaxaca city0.0066151See
BRABrazil REDOME Roraima0.00664140See
MEXMexico Mexico City Center0.0065152See
MEXMexico Coahuila, Torreon0.0063396See
BRABrazil Paraná Caucasian1.20.0062641See
BRABrazil Sao Paulo Bauru Mixed0.00603542See
ARGArgentina Corrientes1.30.0060155See
PRTPortugal Leiria0.00601847See
ESPSpain Ibiza0.006088See
ESPSpain Majorca and Minorca0.006090See
BRABrazil Parana Afro Brazilian1.30.006077See
BRABrazil REDOME Parana0.0053341639See
MEXMexico Aguascalientes state0.005395See
MEXMexico Sonora, Hermosillo0.005199See
SDNSudan Khartoum0.005198See
ITAItaly North Pavia pop 30.0050685See
RUSRussia Northwest pop 31.00.0050100See
BRABrazil Pernambuco Mixed0.0050101See
PRTPortugal Center pop 20.0050562See
BRABrazil Parana Mixed race1.10.0050186See
PRTPortugal Lisbon0.005017420See
PRTPortugal Setubal0.00505268See
PRTPortugal Vila Real0.00501167See
PRTPortugal Viseu0.00502915See
USAUSA OPTN Hispanic0.00501580See
CHESwitzerland Geneva pop 20.00481267See
MEXMexico Chihuahua, Ciudad Juarez0.0046106See
MEXMexico Veracruz Rural0.0046539See
MEXMexico Jalisco Rural0.0043585See
MEXMexico Chihuahua Rural0.0042236See
MEXMexico Chiapas Rural0.0041121See
PRTPortugal Aveiro0.00405933See
PRTPortugal Coimbra0.00405057See
PRTPortugal Evora0.0040737See
PRTPortugal Faro0.00401242See
PRTPortugal Porto0.00407937See
TURTurkey pop 20.0040228See
ISRIsrael Moroccan Jews0.0040113See
ESPSpain Murcia0.0040173See
FRAFrance Southeast0.80.0040130See
MEXMexico Mestizo pop 40.0037269See
BRABrazil REDOME Rio Grande do Sul0.0036241329See
MEXMexico Guerrero state0.0035144See
MEXMexico Mexico City Metropolitan Area Rural0.0033150See
MEXMexico Durango, Durango city0.0032153See
MEXMexico Durango Rural0.0031326See
MEXMexico Guanajuato Rural0.0031162See
GBRUnited Kingdom East0.0031163See
MEXMexico Oaxaca Rural0.0031485See
MEXMexico Tlaxcala Rural0.0030830See
BRABrazil Rio Grande do Sul Caucasoid0.00304428See
MEXMexico Puebla, Puebla city0.00301994See
MEXMexico Jalisco, Zapopan0.0030168See
BRABrazil Parana Caucasian0.60.00302775See
TWNTaiwan Chinese immigrants from South China0.0030172See
PRTPortugal South pop 20.00301021See
ARGArgentina Buenos Aires pop 20.50.00301216See
PRTPortugal Santarem0.00303865See
PRTPortugal Portalegre0.00301254See
AREUnited Arab Emirates pop 20.50.0030373See
RUSRussia Northwest pop 20.60.0030346See
PRTPortugal Braga0.00301971See
SAUSaudi Arabia pop 20.0030383See
PRTPortugal North pop 20.00291801See
BRABrazil REDOME Santa Catarina0.0029106673See
FRAFrance Marseille0.50.00271000See
RUSRussia Northwest0.50.00251011See
ECUEcuador Mixed Ancestry0.00211173See
ECUEcuador Coast Mixed Ancestry0.0021238See
BRABrazil Curitiba-Parana Mixed0.0021264See
MEXMexico Jalisco, Guadalajara city0.00211189See
SVKSlovakia pop 20.00204234See
TWNTaiwan Chinese immigrants from Middle China0.0020211See
BRABrazil Parana Cafuzo0.30.0020319See
PRTPortugal Beja0.0020699See
USAUSA OPTN Caucasian0.00208525See
ARGArgentina Cuyo Region0.50.0020420See
CHNChina Shaanxi Province Han0.002010000See
MEXMexico Zacatecas Rural0.0019266See
ECUEcuador Andes Mixed Ancestry0.0018824See
FRAFrance Lyon0.30.00174813See
CHESwitzerland Zurich0.00174875See
ESPSpain, Castilla y Leon, Northwest,0.20.00161743See
GBRUnited Kingdom North0.0015330See
ROMRomania pop 30.30.00141469See
CHESwitzerland Lausanne0.0014993See
MEXMexico Puebla Rural0.0012833See
FRAFrance Grenoble0.20.00111000See
SWESweden pop 40.20.0010966See
SAUSaudi Arabia pop 40.20.0010499See
ITAItaly Lombardy0.20.0010674See
SRBSerbia Vojvodina0.20.0010400See
WALWales pop 20.20.001039979See
IRNIran Royan Cord Blood Bank0.10.001015600See
ENGEngland Liverpool0.20.00101343See
ENGEngland Leeds0.20.00105024See
ENGEngland Newcastle0.20.00102739See
ITAItaly North Pavia pop 20.20.00102416See
FRAFrance Grenoble, Nantes and Rennes0.00106094See
ITAItaly South Campania Region0.20.00101089See
TWNTaiwan Hakka pop 20.0010714See
TWNTaiwan Minnan pop 20.00107137See
ARGArgentina Buenos Aires0.20.0010466See
INDIndia North pop 30.0009587See
MEXMexico Mexico City North0.0007751See
CHESwitzerland Bern0.00073545See
GRCGreece pop 70.000611250See
FRAFrance Rennes pop 40.10.00051000See
FRAFrance Bordeaux0.10.0005990See
CHNChina Shanghai0.000526266See
ENGEngland Sheffield0.10.00054755See
IRLIreland South pop 20.000317624See
NORNorway ethnic Norwegians0.10.00034510See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
GBRUnited Kingdom Central0.0000135See
GBRUnited Kingdom Orkney0.000088See
MEXMexico Mexico City East0.000079See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Nayarit Rural0.000064See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Basel0.00001888See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CMRCameroon Ewondo0.000038See
CMRCameroon Uldeme0.000035See
GBRUnited Kingdom South West0.0000163See
SVNSlovenia pop 30.00.0000130See
ITAItaly Sardinia pop30.0000100See
SCOScotland Orkney0.00.000099See
TWNTaiwan Chinese immigrants from North China0.0000152See
ISRIsrael Ashkenazi Jews pop 20.0000132See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
ARGArgentina Rosario Toba0.00.000086See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
KORSouth Korea pop 10.0000324See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
USAUSA South Texas Hispanic0.0000194See
ESPSpain Majorcans Jews0.0000103See
MEXMexico Mestizo0.00.000041See
TTOTrinidad South Asian0.000087See
GRCGreece North0.0000500See
PAKPakistan Burusho0.000092See
PAKPakistan Mixed Sindhi0.0000101See
VENVenezuela Colonia Tovar0.000086See
MEXMexico Huasteca Region Teenek0.000055See
TURTurkey pop 50.0000142See
MKDMacedonia pop 40.0000216See
CHNChina Jiangsu Province0.000020248See
HRVCroatia pop 20.0000100See
SWESweden Stockholm0.10.00001347See
CHNChina Yunnan Province Naxi0.0000118See
CHNChina Guangdong Province0.00.0000403See
CHNChina Shandong Province0.10.00007418See
PRTPortugal Bragança0.0000301See
PRTPortugal Castelo Branco0.0000327See
RUSRussia Moscow0.00002650See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
MEXMexico Mexico City Mestizo0.0000121See
BIHBosnia and Herzegovina0.0000134See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Baja California, Tijuana0.000025See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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