Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 149 time(s) and present in 99 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
AUSAustralia Kimberly Aborigine0.681041See
AUSAustralia Yuendumu Aborigine0.4400191See
AUSAustralia Groote Eylandt Aborigine0.320075See
PNGPapua New Guinea East New Britain Rabaul0.302060See
PNGPapua New Guinea West Schrader Ranges Haruai0.292055See
AUSAustralia Cape York Peninsula Aborigine0.2910103See
TWNTaiwan Ami40.80.219098See
NZLNew Zealand Polynesians with Full Ancestry38.10.214021See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.205057See
NZLNew Zealand Polynesians with Admixed History37.00.204027See
MYSMalaysia Sarawak Bau Bidayuh0.180025See
NCLNew Caledonia0.155065See
USAUSA NMDP Filipino0.152450614See
PNGPapua New Guinea Madang0.136065See
PHLPhilippines Ivatan24.00.130050See
PNGPapua New Guinea Wanigela Keapara0.127066See
USAUSA NMDP Hawaiian or other Pacific Islander0.102811499See
ASMAmerican Samoa0.100051See
PNGPapua New Guinea Wosera Abelam0.0900131See
SGPSingapore SGVP Malay MAS0.089089See
IDNIndonesia Java pop 20.083036See
MYSMalaysia Perak Grik Jehai0.080025See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0751233See
IDNIndonesia Java Western14.00.0730236See
NZLNew Zealand Maori with Admixed History12.40.0670105See
IDNIndonesia Sundanese and Javanese0.0670201See
SGPSingapore Riau Malay0.0600132See
MYSMalaysia Peninsular Malay11.20.0589951See
NZLNew Zealand Maori with Full Ancestry10.90.054046See
MYSMalaysia Champa10.30.052029See
PNGPapua New Guinea Karimui Plateau Pawaia0.048080See
TWNTaiwan Puyuma8.00.040050See
SGPSingapore Javaneses0.030051See
CHNChina Shanxi HIV negative0.023022See
MYSMalaysia Jelebu Temuan0.021025See
MYSMalaysia Kelantan3.60.018028See
USAUSA Asian0.0180358See
CHNChina Southwest Dai0.0160124See
USAUSA Asian pop 20.01581772See
ESPSpain Catalonia Girona0.011088See
TWNTaiwan Paiwan2.00.010051See
SGPSingapore Thai0.0100100See
AREUnited Arab Emirates Abu Dhabi0.009652See
TWNTaiwan Hakka1.80.009055See
USAUSA NMDP Vietnamese0.007043540See
USAUSA African American pop 20.0070149See
VNMVietnam Hanoi Kinh pop 20.0060170See
ZAFSouth Africa Worcester1.00.0060159See
USAUSA NMDP Southeast Asian0.005827978See
INDIndia Delhi pop 21.10.005090See
MEXMexico Guadalajara Mestizo pop 20.0050103See
CHNChina South Han0.0050284See
CHNChina Canton Han0.0040264See
HKGHong Kong Chinese0.50.0030569See
USAUSA San Diego0.60.0030496See
SGPSingapore Chinese0.70.0030149See
MEXMexico Mexico City Mestizo pop 20.0021234See
TWNTaiwan Tzu Chi Cord Blood Bank0.0020710See
USAUSA Hispanic0.0020234See
ZWEZimbabwe Harare Shona0.0020230See
MYSMalaysia Peninsular Indian0.40.0018271See
HKGHong Kong Chinese BMDR0.00147595See
HKGHong Kong Chinese cord blood registry0.00133892See
DEUGermany DKMS - China minority0.00121282See
USAUSA NMDP Chinese0.001199672See
USAUSA NMDP Alaska Native or Aleut0.00101376See
TWNTaiwan Han Chinese0.0010504See
USAUSA Caucasian0.20.001061655See
CHNChina Marrow Donor Registry0.0010600See
AREUnited Arab Emirates Pop 10.0010570See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000946682See
USAUSA NMDP Japanese0.000624582See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA African American pop 40.00042411See
USAUSA NMDP Mexican or Chicano0.0004261235See
SAUSaudi Arabia pop 6 (G)0.000428927See
DEUGermany DKMS - Turkey minority0.00034856See
CHNChina Jiangsu Han0.00023238See
DEUGermany DKMS - Croatia minority0.00022057See
USAUSA Hispanic pop 20.00031999See
USAUSA NMDP Hispanic South or Central American0.0002146714See
USAUSA NMDP North American Amerindian0.000235791See
USAUSA NMDP South Asian Indian0.0001185391See
CZECzech Republic NMDR0.00015099See
DEUGermany pop 80.000139689See
CHNChina Hubei Han0.00.00013732See
JPNJapan pop 160.000118604See
INDIndia West UCBB0.00.00015829See
USAUSA NMDP African American pop 20.0001416581See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP African0.000028557See
USAUSA NMDP Caribean Black0.000033328See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
TWNTaiwan Tao0.00.000050See
USAUSA North American Native0.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Caucasian pop 30.000088See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
POLPoland DKMS0.000020653See
ESPSpain Gipuzkoa Basque0.0000100See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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