Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 402 time(s) and present in 387 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.349153See
MEXMexico Huasteca Region Teenek0.342055See
MEXMexico Yucatan, Merida0.2795192See
MEXMexico Yucatan Rural0.2761132See
COLColombia San Basilio de Palenque0.262042See
MEXMexico Quintana Roo, Cancun0.260448See
MEXMexico Colima, Colima city0.254161See
MEXMexico Campeche, Campeche city0.250034See
ARGArgentina Chiriguano43.40.245054See
MEXMexico Tlaxcala, Tlaxcala city0.2348181See
MEXMexico Quintana Roo Rural0.230050See
MEXMexico Guanajuato, Guanajuato city0.227322See
MEXMexico Nayarit Rural0.195364See
MEXMexico Mexico City East0.193879See
MEXMexico Jalisco, Tlaquepaque0.192339See
MEXMexico Campeche Rural0.191547See
MEXMexico Chiapas Rural0.1901121See
MEXMexico Oaxaca Rural0.1848485See
BFABurkina Faso Rimaibe0.181047See
MEXMexico Baja California Rural0.180050See
MEXMexico Tabasco, Villahermosa0.176882See
MEXMexico Tabasco Rural0.1761142See
MEXMexico Tlaxcala Rural0.1753830See
MEXMexico Puebla, Puebla city0.17381994See
MEXMexico Coahuila, Saltillo0.171272See
MEXMexico Mexico City Metropolitan Area Rural0.1711150See
MEXMexico Puebla Rural0.1679833See
MEXMexico Mexico City West0.166733See
MEXMexico Queretaro, Queretaro city0.166745See
GTMGuatemala, Guatemala City Mixed Ancestry30.70.1654127See
MEXMexico Veracruz Rural0.1627539See
MEXMexico Michoacan Tarasco29.20.1610130See
MEXMexico Hidalgo Rural0.160581See
GTMGuatemala Mayan0.1580132See
MEXMexico Tamaulipas, Ciudad Victoria0.152223See
MEXMexico Mexico City Mestizo pop 30.1520256See
MEXMexico Mexico City North0.1507751See
MEXMexico San Luis Potosi, San Luis Potosi city0.150030See
MEXMexico Morelos Rural0.150030See
MEXMexico Nayarit, Tepic0.149597See
MEXMexico San Luis Potosi Rural0.149487See
MEXMexico Guanajuato, Leon0.147478See
GHAGhana Accre Asutuare Akan0.1460429See
MEXMexico Tapachula, Chiapas Mestizo Population23.60.145872See
MEXMexico Baja Californa, Mexicali0.1450100See
MEXMexico Veracruz, Coatzacoalcos0.142955See
MEXMexico Veracruz, Veracruz city0.1424171See
MEXMexico Oaxaca, Oaxaca city0.1424151See
MEXMexico Guerrero state0.1424144See
MEXMexico Chiapas, Tuxtla Gutierrez0.141552See
MEXMexico Puebla Mestizo0.141099See
MEXMexico Mexico City South0.134652See
MEXMexico Mestizo24.40.134041See
MEXMexico Veracruz, Poza Rica0.133345See
MEXMexico Jalisco, Tlajomulco0.133330See
CHLChile Santiago0.1332920See
MEXMexico Mexico City Center0.1331152See
ARGArgentina Salta Wichi pop 221.10.132019See
MEXMexico Jalisco, Zapopan0.1310168See
MEXMexico Mexico City Mestizo0.1280121See
MMRMyanmar Chin21.80.127355See
MEXMexico Jalisco, Guadalajara city0.12691189See
MEXMexico Zacatecas Rural0.1264266See
BOLBolivia La Paz Aymaras0.126087See
MEXMexico Veracruz, Xalapa0.1257187See
ZAFSouth Africa Natal Zulu23.00.1250100See
MEXMexico Michoacan, Morelia0.1225150See
ARGArgentina Rosario Toba22.10.122086See
ZAFSouth Africa Tswana24.40.122041See
MEXMexico Michoacan Rural0.1218348See
MEXMexico Nuevo Leon Rural0.1205439See
MEXMexico Baja California, Tijuana0.120025See
MEXMexico Baja California, La Paz0.120075See
MEXMexico Jalisco Rural0.1160585See
MEXMexico Tamaulipas Rural0.1151125See
SDNSudan South Nuba21.70.115146See
INDIndia Kerala Hindu Namboothiri0.113040See
MEXMexico Chihuahua, Ciudad Juarez0.1111106See
BRABrazil Parana Afro Brazilian22.10.110077See
VENVenezuela Caracas Mestizo0.110050See
MEXMexico Hidalgo, Pachuca0.109841See
MEXMexico Veracruz, Orizaba0.108360See
MEXMexico Veracruz, Cordoba0.107156See
USAUSA OPTN Hispanic0.10401580See
ECUEcuador Amazonia Mixed Ancestry0.102639See
MEXMexico Colima Rural0.102343See
SAUSaudi Arabia pop 20.1020383See
BOLBolivia Quechua0.101469See
MEXMexico Sonora, Ciudad Obregón0.1014143See
SAUSaudi Arabia pop 418.40.1002499See
MEXMexico Durango, Durango city0.1000153See
MEXMexico Durango Rural0.0994326See
MEXMexico Guanajuato Rural0.0982162See
MEXMexico Sonora, Hermosillo0.096099See
MEXMexico Zacatecas, Fresnillo0.0952103See
MEXMexico Chihuahua Rural0.0941236See
MARMorocco Casablanca0.0940100See
MEXMexico Coahuila, Torreon0.0938396See
ISRIsrael Ashkenazi Jews pop 20.0930132See
MEXMexico Sinaloa, Culiacán0.0922103See
MEXMexico Morelos, Cuernavaca0.091582See
MEXMexico Sonora Rural0.0914197See
USAUSA OPTN African American0.09101510See
TTOTrinidad African0.090067See
BRABrazil Pernambuco Mixed0.0890101See
NORNorway Sami0.0890200See
MEXMexico Nuevo Leon, Monterrey city0.0885226See
TUNTunisia pop 30.0880104See
ARGArgentina Cuyo Region16.60.0870420See
ECUEcuador Mixed Ancestry0.08611173See
CUBCuba Mixed pop 20.0860189See
RUSRussia South Ural Bashkir17.10.0860146See
CMRCameroon Bamileke 20.086035See
GEOGeorgia Kurds0.086030See
MEXMexico Jalisco, Tonala0.085735See
ECUEcuador Andes Mixed Ancestry0.0850824See
MEXMexico Aguascalientes state0.084295See
ECUEcuador Coast Mixed Ancestry0.0840238See
AREUnited Arab Emirates pop 216.10.0840373See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.084096See
MEXMexico Chihuahua Chihuahua City0.0840119See
COLColombia Wayu from Guajira Peninsula0.083348See
MEXMexico Zacatecas, Zacatecas city0.083384See
MEXMexico Coahuila Rural0.0826216See
MEXMexico Sinaloa Rural0.0820183See
MEXMexico Mestizo pop 40.0818269See
PRTMadeira pop 20.0780173See
BRABrazil Minas Gerais State Mixed14.20.07601000See
BRABrazil REDOME Acre0.0757859See
MEXMexico Sinaloa Capomos Mayo Yoremes0.075060See
BRABrazil REDOME Amapa0.074817864See
COLColombia Barranquilla0.0745188See
BRABrazil REDOME Roraima0.07434140See
BRABrazil South Ribeirao Preto0.0740184See
BGDBangladesh Dhaka Bangalee0.0740141See
BRABrazil REDOME Para0.073772637See
BRABrazil REDOME Bahia0.072847399See
BRABrazil REDOME Amazonas0.072024129See
SDNSudan Khartoum0.071598See
BRABrazil REDOME Mato Grosso do Sul0.071395667See
CMRCameroon Uldeme0.071035See
CUBCuba Mixed Race14.30.071042See
BRABrazil Para State13.90.07105000See
BRABrazil REDOME Mato Grosso0.070934649See
BRABrazil Para Cord Blood Unit13.80.0708841See
TTOTrinidad South Asian0.070087See
LKASri Lanka Colombo Sinhalese0.0690101See
ARGArgentina Buenos Aires13.50.0690466See
PERPeru Arequipa Mestizo13.50.0680168See
BRABrazil REDOME Espirito Santo0.067888485See
BRABrazil REDOME Alagoas0.067325349See
BRABrazil REDOME Paraiba0.067243868See
BRABrazil REDOME Rondonia0.067254396See
BRABrazil REDOME Tocantins0.067120692See
BIHBosnia and Herzegovina0.0671134See
RUSRussia Chuvash0.067082See
BRABrazil REDOME Ceara0.0664101217See
BRABrazil Rio Grande do Norte Mestizo0.066012973See
BRABrazil Piaui Mixed0.066021943See
BRABrazil REDOME Maranhao0.065810180See
BRABrazil REDOME Piaui0.065746140See
BRABrazil REDOME Rio Grande do Norte0.065646603See
BRABrazil South East Cord Blood0.065311409See
BRABrazil REDOME Rio de Janeiro0.0641139322See
PRTPortugal Castelo Branco0.0640327See
ENGEngland London Ashkenazi Jews0.0640500See
BRABrazil Parana Mixed race12.90.0640186See
BRABrazil REDOME Pernambuco0.063592332See
BRABrazil REDOME Minas Gerais0.0635211275See
MEXMexico Sinaloa Mestizo0.063056See
ARGArgentina Buenos Aires pop 212.40.06301216See
PRTPortugal Center pop 20.0630562See
MKDMacedonia MBMDR - Albanian12.50.0625128See
BRABrazil Paraná Caucasian12.20.0624641See
JORJordan Amman0.0620146See
PRTPortugal Santarem0.06203865See
DEUGermany Essen12.10.0610174See
BRABrazil REDOME Federal District0.060729549See
BRABrazil REDOME Sergipe0.06027321See
BRABrazil Rio Grande do Sul Black0.0600248See
ESPSpain Majorcans Jews0.0600103See
BRABrazil Parana Cafuzo11.90.0600319See
BRABrazil REDOME Goias0.059888574See
BRABrazil REDOME Sao Paulo0.0593800809See
PRTMadeira pop 30.0590538See
ESPSpain Pas Valley0.059088See
MEXMexico Queretaro Rural0.058143See
BRABrazil Rio Grande do Sul Mixed0.0580324See
SAUSaudi Arabia11.10.057118See
ESPSpain North Cabuerniga0.057095See
BRABrazil REDOME Parana0.0570341639See
ENGEngland North West Mixed pop 211.40.0567379See
ITAItaly North Pavia0.056081See
MMRMyanmar Shan11.10.055654See
BRABrazil Sao Paulo Bauru Mixed0.05503542See
ARGArgentina Corrientes9.70.0550155See
ARGArgentina La Plata11.00.0550100See
FRAFrance Southeast10.80.0550130See
ISRIsrael Moroccan Jews0.0540113See
PERPeru Lamas City Lama0.054083See
PRTPortugal Viseu0.05402915See
GBRUnited Kingdom Central0.0524135See
PRTPortugal Beja0.0520699See
BRABrazil Parana Caucasian10.30.05202775See
ESPSpain Ibiza0.052088See
BRABrazil REDOME Rio Grande do Sul0.0516241329See
BRABrazil REDOME Santa Catarina0.0515106673See
SWESweden Uppsala10.00.0513300See
PRTAzores Terceira Island0.0510130See
PRTPortugal South pop 20.05101021See
PRTPortugal Lisbon0.051017420See
PRTPortugal Portalegre0.05101254See
IRNIran pop 40.0509855See
IRQIraq Arabs10.10.0503149See
INDIndia North pop 30.0500587See
FRAFrance Rennes pop 30.0500200See
VENVenezuela Zulia Maracaibo Mixed0.050020See
VENVenezuela Zulia San Jose de Heras Mixed0.050020See
ITAItaly Rome10.00.0500100See
MKDMacedonia pop 40.0490216See
SWESweden Stockholm9.80.04901347See
INDIndia Kerala Hindu Nair0.049041See
GRCGreece North0.0480500See
PRTPortugal Setubal0.04805268See
PRTPortugal Faro0.04801242See
ALBAlbania pop 29.00.0475432See
RUSRussia North Ossetian9.40.0472127See
IRQIraq Erbil9.40.0471372See
BRABrazil Curitiba-Parana Mixed0.0471264See
IRNIran pop 10.047064See
ARMArmenia Yerevan0.0470445See
PRTPortugal Porto0.04707937See
RUSRussia Tatars0.0464355See
BRABrazil Rio Grande do Sul Caucasoid0.04604428See
PRTPortugal Aveiro0.04605933See
PRTPortugal Guarda0.0460797See
MARMorocco pop 20.0460110See
PRTPortugal Coimbra0.04505057See
PRTPortugal Vila Real0.04501167See
BRABrazil Parana Oriental9.10.045033See
PRTPortugal North pop 20.04421801See
RUSRussia South Ural Tatar8.10.0440135See
FRAFrance Reims0.0440102See
ISRIsrael Jews pop 28.60.044023000See
FRAFrance Lyon8.50.04334813See
ESPSpain Sevilla8.60.0432278See
SVNSlovenia pop 38.50.0430130See
PRTPortugal Evora0.0430737See
USAUSA OPTN Caucasian0.04308525See
NORNorway ethnic Norwegians8.40.04304510See
FRAFrance Marseille8.60.04291000See
MKDMacedonia MBMDR - Macedonian8.40.04251283See
SWESweden pop 48.30.0424966See
ENGEngland Lancaster8.30.0424545See
SRBSerbia pop 38.20.04221992See
FRAFrance Grenoble8.30.04201000See
PRTPortugal Viana do Castelo0.0420706See
PRTPortugal Bragança0.0420301See
INDIndia Kerala Hindu Ezhava0.042024See
FRAFrance Rennes pop 48.20.04151000See
ENGEngland Newcastle8.10.04132739See
PRTPortugal Braga0.04101971See
PRTPortugal Leiria0.04101847See
NORNorway pop 20.0410576See
ARMArmenia living in USA0.0410233See
GRCGreece pop 70.040411250See
IRNIran Royan Cord Blood Bank7.90.040015600See
ITAItaly East Sicily8.00.040050See
ITAItaly Lombardy7.70.0400674See
BRABrazil Sao Paulo Mixed0.80.0400239See
ITAItaly North Pavia pop 30.0398685See
MKDMacedonia MBMDR - Macedonian Muslims7.90.039576See
ENGEngland Leeds7.70.03925024See
ENGEngland Sheffield7.70.03924755See
WALWales pop 27.60.039039979See
POLPoland pop 37.80.03882907See
RUSRussia Moscow0.03802650See
KURIraq Kurdistan Region7.70.0380209See
TURTurkey pop 50.0380142See
MKDMacedonia pop 30.0380172See
FRAFrance Grenoble, Nantes and Rennes0.03806094See
SVKSlovakia pop 20.03764234See
BIHBosnia and Herzegovina pop 27.50.0375120See
ENGEngland Liverpool7.30.03711343See
RUSRussia Samara Region0.03702500See
ARMArmenia Ghegharkunik0.0370242See
ESPSpain, Castilla y Leon, Northwest,7.50.03601743See
SRBSerbia Vojvodina7.00.0360400See
GAZGaza Palestinians0.0360165See
IRLIreland South pop 20.036017624See
ITAItaly North Pavia pop 27.00.03602416See
ESPSpain Murcia0.0360173See
ESPSpain Majorca0.0360407See
RUSRussia Moscow Pop 27.10.03552000See
ITAItaly pop 67.10.0353184See
GRCGreece pop36.90.0351246See
TURTurkey pop 20.0350228See
RUSRussia Northwest pop 37.00.0350100See
RUSRussia South Ural Russian6.80.0340207See
ENGEngland Manchester6.70.03401640See
ROMRomania pop 36.70.03381469See
CZECzech Republic Kurd6.80.033874See
ALBAlbanian Kosovo0.0333120See
ARMArmenia Shirak0.033076See
INDIndia Kerala Syrian Christian0.032031See
RUSRussia Northwest6.30.03201011See
AUSAustralia West Caucasian6.20.0310891See
ARMArmenia living in Lebanon0.0310368See
GBRUnited Kingdom South West0.0307163See
DZAAlgeria pop 26.00.0304106See
RUSRussia Arkhangelsk Pomor0.030063See
ROMRomania pop 20.03006936See
TUNTunisia Ghannouch0.030082See
GBRUnited Kingdom pop 20.0300101See
ARMArmenia living in Karabakh0.0300445See
RUSRussia Transbaikal Territory Buryats6.00.0300150See
INDIndia North Gujarat5.60.0296338See
FRAFrance Bordeaux5.80.0290990See
INDIndia Kerala Malabar Muslim0.029034See
GBRUnited Kingdom North0.0287330See
RUSRussia Northwest pop 25.50.0280346See
MNGMongolia Ulaanbaatar Khalkha0.026041See
INDIndia sub-Himalayan West Bengal Kami5.10.0253158See
HRVCroatia pop 20.0250100See
ESPSpain North Cantabria0.024083See
ARMArmenia living in Iran0.024085See
GBRUnited Kingdom Orkney0.022988See
USAUSA OPTN Asian0.0220261See
ITAItaly South Campania Region4.30.02171089See
HRVCroatia pop 34.20.0208120See
ARMArmenia Lori0.0200102See
RUSRussia Murmansk Saomi Mixed0.020070See
RUSRussia Nenet Mixed0.020055See
RUSRussia Sakhalin Island Nivkhi0.019053See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks3.60.0180112See
VENVenezuela Colonia Tovar0.017486See
ESPSpain Minorca0.016094See
TWNTaiwan Chinese immigrants from North China0.0160152See
MYSMalaysia pop 20.016062See
MMRMyanmar Mon3.10.015664See
GBRUnited Kingdom East0.0153163See
CHNChina Shaanxi Province Han0.015010000See
MEXMexico Sonora Seri0.015034See
MNGMongolia Khalkha pop 20.0150202See
GRCGreece Crete0.0150135See
MNGMongolia Khalkha0.0150200See
CHNChina Shandong Province Linqu County2.90.0146139See
ESPSpain Arratia Valley Basque0.013083See
CMRCameroon Ewondo0.013038See
ARMArmenia Syunik0.0130117See
CMRCameroon Podokwo0.012043See
CHNChina Wuhan2.50.0120121See
CHNChina Harbin Manchu0.0120172See
CZECzech Republic Romani pop 22.20.010946See
MMRMyanmar Bamar2.20.010946See
MMRMyanmar Rakhine2.10.010448See
PHLPhilippines National Capital Region0.010051See
CHNChina Shandong Province1.80.00907418See
CHNChina Guangdong Province1.70.0085403See
THAThailand pop 40.008016807See
BRABrazil Parana Japanese2.00.0078192See
MYSMalaysia pop 30.00701445See
CHNChina Jiangsu Province0.007020248See
CHNChina Shanghai0.005026266See
TWNTaiwan Chinese immigrants from Middle China0.0050211See
CUBCuba Mixed0.004078See
TWNTaiwan Minnan and Hakka0.0030190See
KORSouth Korea pop 80.00207096See
KORSouth Korea pop 10.0020324See
TWNTaiwan Hakka pop 20.0010714See
TWNTaiwan Minnan pop 20.00107137See
TWNTaiwan Chinese immigrants from South China0.0000172See
TWNTaiwan Aborigine0.0000111See
MNGMongolia Tarialan Khoton0.000085See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Hoton0.000085See
ITAItaly North pop 30.00.000097See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
INDIndia Kerala Hindu Pulaya0.000016See
CHNChina Harbin Korean0.0000201See
CHNChina North Han0.0000105See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
VNMVietnam Hanoi0.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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