Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 245 time(s) and present in 196 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Sierra de Perija Yucpa0.372073See
TZATanzania Maasai27.50.1430336See
STPSao Tome Island Angolar0.139032See
GNBGuinea Bissau Fula0.129031See
STPSao Tome Island Forro0.128066See
ISRIsrael Ethiopia Jews0.11645928See
KENKenya Nandi0.1160240See
ZWEZimbabwe Harare Shona0.0980230See
ZAFSouth Africa Natal Zulu19.00.0950100See
GHAGhana Ga-Adangbe15.30.0802131See
USAUSA African American pop 20.0770149See
KENKenya Luo0.0760265See
TUNTunisia Gabes0.073695See
ZAFSouth Africa Worcester14.00.0720159See
KENKenya, Nyanza Province, Luo tribe12.00.0700100See
UGAUganda Kampala pop 20.0660175See
USAUSA African American pop 40.06512411See
USAUSA NMDP African0.064528557See
USAUSA African American0.0640252See
USAUSA NMDP Caribean Black0.063633328See
MLIMali Bandiagara0.0620138See
USAUSA NMDP African American pop 20.0603416581See
SDNSudan Mixed10.50.0550200See
UGAUganda Kampala0.0520161See
CMRCameroon Baka Pygmy0.050010See
MEXMexico Guadalajara Mestizo pop 20.0490103See
USAUSA NMDP Caribean Indian0.049014339See
CPVCape Verde Southeastern Islands0.048062See
MARMorocco Nador Metalsa pop 20.048073See
ZMBZambia Lusaka0.047044See
ARGArgentina Chiriguano7.50.047054See
BFABurkina Faso Mossi0.047053See
USAUSA African American pop 30.0470564See
ISRIsrael YemenJews0.046715542See
ISRIsrael Argentina Jews0.04624307See
CMRCameroon Bamileke0.045077See
USAUSA NMDP Caribean Hispanic0.0440115374See
GNBGuinea Bissau Balanta0.042048See
ISRIsrael USA Jews0.04206058See
GNBGuinea Bissau Papel0.040025See
USAUSA African American Bethesda7.90.0400187See
ECUEcuador Amerindians0.039763See
ISRIsrael Morocco Jews0.039536718See
ISRIsrael Poland Jews0.039213871See
ISRIsrael Ashkenazi Jews pop 30.03824625See
PRTAzores Oriental Islands0.038043See
CMRCameroon Sawa0.038013See
ISRIsrael USSR Jews0.036945681See
ISRIsrael Tunisia Jews0.03679070See
ISRIsrael Georgia Jews0.03664471See
CUBCuba Mixed Race7.10.036042See
BRABrazil Mixed0.0350108See
PAKPakistan Kalash0.033069See
NICNicaragua Managua6.30.0329339See
CMRCameroon Beti0.0320174See
ISRIsrael Arab pop 20.031512301See
FRAFrance Southeast6.20.0310130See
MEXMexico Sonora Seri0.030034See
MEXMexico Mexico City Mestizo pop 20.0299234See
CHESwitzerland Lugano0.02911169See
CUBCuba Caucasian5.70.029070See
CMRCameroon Yaounde0.028092See
MEXMexico Mexico City Mestizo population0.0280143See
ISRIsrael Bukhara Jews0.02782317See
CHESwitzerland St Gallen0.02602113See
ISRIsrael Kavkazi Jews0.02552840See
ISRIsrael Libya Jews0.02513739See
USAUSA NMDP Hispanic South or Central American0.0248146714See
USAUSA Hispanic pop 20.02461999See
COLColombia Bogotá Cord Blood4.90.02431463See
GNBGuinea Bissau0.023065See
CHESwitzerland Aargau-Solothurn0.02201838See
USAUSA Hispanic0.0210234See
CHESwitzerland Luzern0.02021553See
PRTPortugal South0.020049See
BFABurkina Faso Fulani0.020049See
USAUSA NMDP Mexican or Chicano0.0185261235See
IRNIran Yazd0.017956See
AREUnited Arab Emirates Pop 10.0170570See
CHESwitzerland Zurich0.01654875See
DEUGermany DKMS - Spain minority0.01631107See
FRAFrance Corsica Island0.0160100See
PAKPakistan Baloch0.016066See
SENSenegal Niokholo Mandenka0.0160165See
USAUSA San Francisco Caucasian0.0160220See
CHESwitzerland Sion0.0155832See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.10.01554335See
AUSAustralia New South Wales Caucasian0.0150134See
ESPSpain Andalusia0.015099See
USAUSA Philadelphia Caucasian3.00.0150141See
DEUGermany DKMS - Portugal minority0.01491176See
SAUSaudi Arabia Guraiat and Hail2.80.0140213See
SCOScotland Orkney2.80.014099See
CHESwitzerland Geneva pop 20.01331267See
PRTPortugal Azores Terceira Island2.60.0132130See
CHESwitzerland Basel0.01271888See
GRCGreece pop 60.0124242See
USAUSA NMDP American Indian South or Central America0.01205926See
MEXMexico Mestizo2.40.012041See
NCLNew Caledonia0.012065See
PRTAzores Terceira Island0.0120130See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
USAUSA NMDP Middle Eastern or North Coast of Africa0.011270890See
USAUSA San Diego2.30.0110496See
ITAItaly Bergamo2.00.0110101See
BRABrazil Belo Horizonte Caucasian2.10.011095See
IRNIran Baloch0.0110100See
CHESwitzerland Graubunden0.0105759See
ZAFSouth Africa Caucasians0.0100102See
CHNChina North Han0.0100105See
CHLChile Santiago Mixed2.00.010070See
PRTPortugal Center0.010050See
AREUnited Arab Emirates Abu Dhabi0.009652See
FRAFrance French Bone Marrow Donor Registry0.009042623See
NIRIreland Northern1.80.00901000See
MEXMexico Oaxaca Mixe0.009055See
CZECzech Republic0.0090106See
USAUSA Caucasian pop 20.0090265See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0090146See
USAUSA NMDP European Caucasian0.00841242890See
CPVCape Verde Northwestern Islands0.008062See
USAUSA North American Native0.0080187See
USAUSA NMDP North American Amerindian0.007935791See
DEUGermany DKMS - France minority0.00771406See
DEUGermany DKMS - Austria minority0.00771698See
DEUGermany DKMS - Italy minority0.00751159See
DEUGermany pop 80.007239689See
CHESwitzerland Lausanne0.0072993See
ITAItaly pop 50.0070975See
NLDNetherlands Leiden0.00701305See
ENGEngland North West1.30.0070298See
USAUSA Eastern European0.0070558See
DEUGermany pop 60.00718862See
USAUSA Caucasian Bethesda1.40.0070307See
DEUGermany DKMS - German donors0.00683456066See
USAUSA Caucasian pop 40.00651070See
ESPSpain Majorca and Minorca0.006090See
IRLIreland South1.20.0060250See
GEOGeorgia Svaneti Region Svan0.006080See
ECUEcuador Cayapa0.0060183See
ESPSpain Andalusia Romani0.006099See
USAUSA Caucasian pop 30.006088See
USAUSA San Antonio Caucasian0.0060222See
HRVCroatia pop 40.00604000See
USAUSA NMDP Alaska Native or Aleut0.00601376See
GRCGreece pop 81.20.006083See
DEUGermany DKMS - United Kingdom minority0.00601043See
DEUGermany DKMS - Netherlands minority0.00551374See
CZECzech Republic NMDR0.00525099See
MEXMexico Mixtec0.005097See
MEXMexico Oaxaca Jamiltepec Mixtec0.005096See
USAUSA South Dakota Lakota Sioux0.0050302See
RUSRussia Bering Island Aleuts0.0048104See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00491028See
POLPoland DKMS0.004720653See
MEXMexico Chiapas Lacandon Mayans0.0046218See
DEUGermany DKMS - Turkey minority0.00464856See
CHESwitzerland Bern0.00463545See
USAUSA NMDP Hawaiian or other Pacific Islander0.004511499See
DEUGermany DKMS - Romania minority0.00451234See
DEUGermany DKMS - Greece minority0.00421894See
RUSRussia Karelia0.00421075See
DEUGermany DKMS - Croatia minority0.00412057See
SGPSingapore Riau Malay0.0040132See
MEXMexico Mexico City Tlalpan0.60.0030330See
CHNChina Jiangsu Province Han0.0018334See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ISRIsrael Iraq Jews0.001013270See
ISRIsrael Druze0.00095914See
USAUSA NMDP Filipino0.000950614See
USAUSA NMDP Southeast Asian0.000827978See
HKGHong Kong Chinese cord blood registry0.00043892See
ISRIsrael Iran Jews0.00048153See
USAUSA NMDP Vietnamese0.000443540See
USAUSA NMDP Japanese0.000324582See
CHNChina Jiangsu Han0.00033238See
USAUSA NMDP South Asian Indian0.0003185391See
INDIndia West UCBB0.10.00035829See
INDIndia Central UCBB0.10.00024204See
INDIndia South UCBB0.00.000211446See
USAUSA Asian pop 20.00031772See
HKGHong Kong Chinese BMDR0.00027595See
USAUSA NMDP Chinese0.000199672See
INDIndia North UCBB0.00.00015849See
USAUSA NMDP Korean0.000177584See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
GNBGuinea Bissau Bijago0.000023See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
ITAItaly Sardinia pop30.0000100See
CHNChina Tibet Region Tibetan0.0000158See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
KORSouth Korea pop 30.0000485See
AUSAustralia Yuendumu Aborigine0.0000191See
PAKPakistan Karachi Parsi0.000091See
PRTAzores Central Islands0.000059See
USAUSA South Texas Hispanic0.0000194See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
USAUSA Asian0.0000358See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
PRTPortugal North0.000046See
HKGHong Kong Chinese0.00.0000569See
MEXMexico Oaxaca Mixtec0.0000103See
MEXMexico Oaxaca Zapotec0.000090See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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