Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 215 time(s) and present in 155 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CPVCape Verde Northwestern Islands0.040062See
ISRIsrael Arab Druze0.0300101See
ISRIsrael Druze0.02505914See
CPVCape Verde Southeastern Islands0.024062See
CHNChina Guizhou Province Miao pop 20.024085See
ARGArgentina Rosario Toba4.70.023086See
ISRIsrael YemenJews0.022315542See
ISRIsrael Arab pop 20.020712301See
BFABurkina Faso Mossi0.019053See
ISRIsrael Ashkenazi Jews pop 30.01634625See
ISRIsrael USA Jews0.01576058See
ISRIsrael Morocco Jews0.015636718See
ISRIsrael Argentina Jews0.01534307See
ARMArmenia combined Regions0.0150100See
MARMorocco Settat Chaouya2.80.014098See
MARMorocco Atlantic Coast Chaouya0.014098See
ISRIsrael Poland Jews0.014013871See
ISRIsrael Libya Jews0.01243739See
MEXMexico Mestizo2.40.012041See
CUBCuba Mixed Race2.40.012042See
INDIndia Delhi pop 22.20.011090See
ITAItaly Bergamo2.00.0110101See
TUNTunisia pop 30.0110104See
TUNTunisia Gabes0.010595See
ISRIsrael Tunisia Jews0.01029070See
ITAItaly Sardinia pop30.0100100See
JORJordan Amman0.0100146See
PRTPortugal Center0.010050See
CHESwitzerland Luzern0.00981553See
ISRIsrael USSR Jews0.009145681See
IRNIran Yazd0.008956See
ISRIsrael Kavkazi Jews0.00862840See
IRNIran Saqqez-Baneh Kurds0.008360See
GRCGreece pop 60.0083242See
IRNIran Kurd pop 20.008060See
IRNIran Gorgan0.008064See
STPSao Tome Island Forro0.008066See
PAKPakistan Baloch0.008066See
RUSRussia Bashkortostan, Tatars1.60.0078192See
NLDNetherlands UMCU1.60.007864See
USAUSA NMDP Middle Eastern or North Coast of Africa0.007670890See
ISRIsrael Iraq Jews0.007413270See
CHNChina Jiangsu Province Han0.0071334See
NICNicaragua Mestizo (G)1.40.0070155See
ESPSpain, Canary Islands, Gran canaria island1.40.0069215See
DEUGermany DKMS - Italy minority0.00651159See
ESPSpain Catalonia Girona0.006088See
CMRCameroon Yaounde0.006092See
NICNicaragua Managua1.20.0060339See
SGPSingapore SGVP. Indian INS0.006086See
IRNIran Baloch0.0060100See
USAUSA San Antonio Caucasian0.0060222See
USAUSA Hispanic0.0060234See
USAUSA Hispanic pop 20.00551999See
IRNIran Tabriz Azeris0.005297See
DEUGermany DKMS - Turkey minority0.00524856See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
CZECzech Republic0.0050106See
SAUSaudi Arabia Guraiat and Hail0.90.0050213See
ZAFSouth Africa Caucasians0.0050102See
TWNTaiwan Minnan pop 11.00.0050102See
CHESwitzerland Aargau-Solothurn0.00491838See
CHESwitzerland Geneva pop 20.00481267See
ISRIsrael Iran Jews0.00418153See
ITAItaly pop 50.0040975See
LBYLibya Cyrenaica0.0040118See
AREUnited Arab Emirates Pop 10.0040570See
FRAFrance Southeast0.80.0040130See
USAUSA South Texas Hispanic0.0040194See
USAUSA Caucasian Bethesda0.80.0040307See
USAUSA Mexican American Mestizo0.0040553See
USAUSA Italy Ancestry0.0040273See
COLColombia Bogotá Cord Blood0.80.00381463See
USAUSA NMDP Mexican or Chicano0.0035261235See
USAUSA NMDP Caribean Hispanic0.0032115374See
SAUSaudi Arabia pop 50.60.0032158See
SAUSaudi Arabia pop 6 (G)0.003228927See
CHNChina Jiangsu Han0.00313238See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00314335See
INDIndia Karnataka Kannada Speaking0.60.0030174See
SDNSudan Mixed0.50.0030200See
UGAUganda Kampala0.0030161See
USAUSA NMDP Hispanic South or Central American0.0028146714See
CHESwitzerland Lausanne0.0027993See
CHNChina Zhejiang Han0.00261734See
DEUGermany DKMS - Greece minority0.00261894See
MYSMalaysia Peninsular Chinese0.50.0026194See
DEUGermany DKMS - Portugal minority0.00261176See
DEUGermany DKMS - Spain minority0.00231107See
CHESwitzerland Graubunden0.0022759See
CHNChina Marrow Donor Registry0.0020600See
IRLIreland South0.40.0020250See
USAUSA Caucasian pop 20.0020265See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA Spain Ancestry0.0020279See
DEUGermany DKMS - France minority0.00181406See
CHESwitzerland Zurich0.00174875See
MEXMexico Mexico City Tlalpan0.30.0015330See
USAUSA NMDP European Caucasian0.00141242890See
USAUSA Asian pop 20.00141772See
CHESwitzerland Bern0.00143545See
DEUGermany DKMS - United Kingdom minority0.00141043See
DEUGermany DKMS - Netherlands minority0.00151374See
INDIndia North UCBB0.20.00125849See
ISRIsrael Ethiopia Jews0.00125928See
ENGEngland Blood Donors of Mixed Ethnicity0.20.0010519See
FRAFrance Grenoble, Nantes and Rennes0.00106094See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA African American pop 30.0010564See
USAUSA Asian0.0010358See
TWNTaiwan Han Chinese0.0010504See
USAUSA NMDP Chinese0.001099672See
USAUSA NMDP African0.000928557See
USAUSA Caucasian pop 40.00091070See
CZECzech Republic NMDR0.00095099See
DEUGermany pop 80.000939689See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
HRVCroatia pop 40.00094000See
USAUSA NMDP Hawaiian or other Pacific Islander0.000811499See
DEUGermany DKMS - German donors0.00083456066See
ISRIsrael Georgia Jews0.00084471See
USAUSA NMDP Southeast Asian0.000827978See
DEUGermany DKMS - China minority0.00081282See
USAUSA NMDP North American Amerindian0.000735791See
RUSRussia Nizhny Novgorod, Russians0.10.00071510See
ISRIsrael Bukhara Jews0.00062317See
POLPoland DKMS0.000620653See
USAUSA NMDP South Asian Indian0.0006185391See
DEUGermany pop 60.00068862See
INDIndia Central UCBB0.10.00054204See
RUSRussia Karelia0.00051075See
CHNChina Hubei Han0.10.00043732See
USAUSA African American pop 40.00042411See
USAUSA NMDP Filipino0.000350614See
USAUSA NMDP Caribean Black0.000333328See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000346682See
DEUGermany DKMS - Austria minority0.00031698See
HKGHong Kong Chinese BMDR0.00037595See
USAUSA NMDP African American pop 20.0002416581See
INDIndia Tamil Nadu0.00022492See
DEUGermany DKMS - Croatia minority0.00022057See
INDIndia West UCBB0.00.00025829See
INDIndia South UCBB0.00.000111446See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP Vietnamese0.000043540See
USAUSA African American0.0000252See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See
USAUSA North American Native0.0000187See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
MARMorocco Nador Metalsa pop 20.000073See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP Malay MAS0.000089See
STPSao Tome Island Angolar0.000032See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
SCOScotland Orkney0.00.000099See
PHLPhilippines Ivatan0.00.000050See
NLDNetherlands Leiden0.00001305See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
MLIMali Bandiagara0.0000138See
NIRIreland Northern0.00.00001000See
ESPSpain Gipuzkoa Basque0.0000100See
ENGEngland Leeds0.00.00005024See
CUBCuba Caucasian0.00.000070See
HKGHong Kong Chinese0.00.0000569See
GNBGuinea Bissau0.000065See
FRAFrance Corsica Island0.0000100See
ESPSpain Majorca and Minorca0.000090See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Guizhou Province Bouyei0.0000109See
CHNChina Guizhou Province Shui0.0000153See
CHESwitzerland Basel0.00001888See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Rimaibe0.000047See
CHNChina North Han0.0000105See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Lugano0.00001169See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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