Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 328 time(s) and present in 230 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Tamaulipas, Ciudad Victoria0.108723See
COLColombia San Basilio de Palenque0.107042See
ZAFSouth Africa Natal Zulu13.00.0650100See
USAUSA OPTN African American0.05401510See
CMRCameroon Ewondo0.053038See
CMRCameroon Podokwo0.047043See
GHAGhana Accre Asutuare Akan0.0420429See
TTOTrinidad African0.040067See
BRABrazil Rio Grande do Sul Black0.0380248See
ZAFSouth Africa Tswana4.90.037041See
CUBCuba Mixed Race7.10.036042See
MEXMexico Campeche Rural0.031947See
CUBCuba Mixed pop 20.0310189See
MEXMexico Campeche, Campeche city0.029434See
BRABrazil REDOME Bahia0.025647399See
BRABrazil Sao Paulo Mixed0.50.0250239See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
BRABrazil REDOME Sergipe0.02227321See
COLColombia Barranquilla0.0215188See
BRABrazil REDOME Piaui0.021146140See
BRABrazil Piaui Mixed0.021021943See
MEXMexico Sonora, Hermosillo0.020299See
BRABrazil REDOME Tocantins0.020120692See
BRABrazil Pernambuco Mixed0.0200101See
MYSMalaysia pop 20.020062See
BRABrazil Parana Afro Brazilian3.90.019077See
BRABrazil REDOME Maranhao0.018410180See
TUNTunisia Ghannouch0.018082See
BRABrazil REDOME Pernambuco0.017792332See
BRABrazil Rio Grande do Norte Mestizo0.017012973See
BRABrazil REDOME Rio de Janeiro0.0167139322See
MEXMexico Veracruz, Orizaba0.016760See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
BRABrazil Para Cord Blood Unit3.30.0167841See
MEXMexico Michoacan, Morelia0.0166150See
BRABrazil REDOME Roraima0.01644140See
BRABrazil REDOME Amapa0.016017864See
BRABrazil Parana Mixed race3.20.0160186See
BRABrazil South Ribeirao Preto0.0160184See
BRABrazil REDOME Alagoas0.015725349See
MEXMexico Nayarit Rural0.015664See
BRABrazil Minas Gerais State Mixed2.90.01501000See
BRABrazil REDOME Rio Grande do Norte0.015046603See
THAThailand Northeast pop 20.0150400See
BRABrazil REDOME Espirito Santo0.014688485See
BRABrazil REDOME Ceara0.0144101217See
BRABrazil REDOME Rondonia0.014354396See
MEXMexico Jalisco, Tonala0.014335See
BRABrazil REDOME Federal District0.014129549See
BRABrazil REDOME Minas Gerais0.0141211275See
CMRCameroon Bamileke 20.014035See
CMRCameroon Uldeme0.014035See
BRABrazil REDOME Amazonas0.013924129See
BRABrazil South East Cord Blood0.013911409See
BRABrazil REDOME Mato Grosso0.013834649See
BRABrazil REDOME Para0.013872637See
MEXMexico Coahuila, Saltillo0.013772See
BRABrazil REDOME Paraiba0.013543868See
BRABrazil REDOME Acre0.0134859See
IRQIraq Arabs2.70.0134149See
BRABrazil REDOME Goias0.013088574See
BRABrazil Para State1.30.01305000See
ECUEcuador Coast Mixed Ancestry0.0126238See
MEXMexico Tabasco, Villahermosa0.012282See
BRABrazil REDOME Mato Grosso do Sul0.012095667See
BRABrazil REDOME Sao Paulo0.0113800809See
BRABrazil Belo Horizonte Caucasian2.10.011095See
AREUnited Arab Emirates pop 22.10.0110373See
TURTurkey pop 50.0110142See
TUNTunisia pop 30.0110104See
MEXMexico Sonora, Ciudad Obregón0.0105143See
MEXMexico Quintana Roo, Cancun0.010448See
MEXMexico Puebla Mestizo0.010099See
MEXMexico Michoacan Rural0.0100348See
SAUSaudi Arabia pop 42.00.0100499See
VNMVietnam Hanoi0.010050See
TTOTrinidad South Asian0.010087See
MEXMexico Veracruz Rural0.0092539See
MYSMalaysia pop 30.00901445See
BRABrazil Parana Cafuzo1.90.0090319See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Veracruz, Coatzacoalcos0.008955See
SAUSaudi Arabia pop 20.0080383See
BRABrazil Sao Paulo Bauru Mixed0.00803542See
CHNChina Yunnan Province Han pop 20.0080129See
MEXMexico Coahuila, Torreon0.0075396See
MEXMexico Zacatecas Rural0.0074266See
BRABrazil REDOME Parana0.0074341639See
BOLBolivia Quechua0.007269See
BRABrazil Rio Grande do Sul Mixed0.0070324See
CUBCuba Caucasian1.40.007070See
MEXMexico Tabasco Rural0.0070142See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.006972See
CZECzech Republic Kurd1.40.006874See
ENGEngland North West Mixed pop 21.30.0066379See
MEXMexico Oaxaca, Oaxaca city0.0066151See
MEXMexico Zacatecas, Zacatecas city0.006084See
ARGArgentina Rosario Toba1.20.006086See
THAThailand pop 40.006016807See
MEXMexico Veracruz, Veracruz city0.0058171See
BRABrazil Paraná Caucasian1.10.0055641See
MEXMexico Veracruz, Xalapa0.0053187See
MEXMexico Nayarit, Tepic0.005297See
MEXMexico Baja Californa, Mexicali0.0050100See
MARMorocco Casablanca0.0050100See
MARMorocco pop 20.0050110See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
MNGMongolia Khalkha0.0050200See
BRABrazil Parana Caucasian1.00.00502775See
USAUSA OPTN Hispanic0.00501580See
MEXMexico Sinaloa, Culiacán0.0049103See
MEXMexico Zacatecas, Fresnillo0.0048103See
BRABrazil REDOME Rio Grande do Sul0.0048241329See
MEXMexico Chihuahua, Ciudad Juarez0.0046106See
MEXMexico Nuevo Leon, Monterrey city0.0044226See
MEXMexico Chihuahua Rural0.0042236See
BRABrazil REDOME Santa Catarina0.0041106673See
ARMArmenia Syunik0.0040117See
PRTPortugal Leiria0.00401847See
MKDMacedonia MBMDR - Albanian0.80.0039128See
MEXMexico Yucatan Rural0.0037132See
BIHBosnia and Herzegovina0.0037134See
ALBAlbania pop 20.70.0035432See
MEXMexico Guerrero state0.0035144See
MEXMexico Jalisco Rural0.0034585See
MEXMexico Jalisco, Guadalajara city0.00341189See
MEXMexico Mexico City Metropolitan Area Rural0.0033150See
FRAFrance Grenoble0.60.00321000See
MEXMexico Guanajuato Rural0.0031162See
PRTMadeira pop 20.0030173See
PRTPortugal Setubal0.00305268See
HKGHong Kong Chinese0.50.0030569See
CHNChina Harbin Manchu0.0030172See
BGDBangladesh Dhaka Bangalee0.0030141See
ARGArgentina Buenos Aires pop 20.60.00301216See
ARMArmenia Yerevan0.0030445See
BRABrazil Rio Grande do Sul Caucasoid0.00304428See
GAZGaza Palestinians0.0030165See
SGPSingapore Chinese0.70.0030149See
ECUEcuador Mixed Ancestry0.00301173See
CHESwitzerland Lausanne0.0027993See
MEXMexico Sinaloa Rural0.0027183See
MEXMexico Yucatan, Merida0.0026192See
BRABrazil Parana Japanese1.00.0026192See
CHNChina Guangdong Province0.50.0025403See
MEXMexico Sonora Rural0.0025197See
ROMRomania pop 30.50.00241469See
MEXMexico Coahuila Rural0.0023216See
PRTPortugal North pop 20.00221801See
CHLChile Santiago0.0022920See
BRABrazil Curitiba-Parana Mixed0.0021264See
MEXMexico Oaxaca Rural0.0021485See
PRTPortugal Lisbon0.002017420See
PRTPortugal Vila Real0.00201167See
PRTPortugal Viseu0.00202915See
PRTPortugal South pop 20.00201021See
PRTPortugal Castelo Branco0.0020327See
PRTPortugal Faro0.00201242See
PRTPortugal Guarda0.0020797See
PRTPortugal Santarem0.00203865See
PRTPortugal Aveiro0.00205933See
PRTPortugal Beja0.0020699See
PRTPortugal Braga0.00201971See
ARMArmenia living in Karabakh0.0020445See
ARMArmenia living in USA0.0020233See
ARGArgentina Cuyo Region0.50.0020420See
ARGArgentina Buenos Aires0.40.0020466See
CHNChina Shaanxi Province Han0.002010000See
GRCGreece North0.0020500See
GRCGreece pop30.40.0020246See
TWNTaiwan Chinese immigrants from Middle China0.0020211See
MEXMexico Mestizo pop 40.0019269See
MEXMexico Puebla, Puebla city0.00181994See
ITAItaly North Pavia pop 30.0017685See
GRCGreece pop 70.001611250See
ITAItaly South Campania Region0.30.00151089See
ENGEngland Liverpool0.30.00151343See
MEXMexico Durango Rural0.0015326See
MEXMexico Mexico City North0.0013751See
FRAFrance Lyon0.20.00124813See
IRNIran pop 40.0012855See
MKDMacedonia MBMDR - Macedonian0.20.00121283See
FRAFrance Bordeaux0.20.0011990See
ENGEngland Lancaster0.20.0010545See
FRAFrance Grenoble, Nantes and Rennes0.00106094See
IRNIran Royan Cord Blood Bank0.20.001015600See
ITAItaly North Pavia pop 20.10.00102416See
ITAItaly Lombardy0.30.0010674See
ISRIsrael Jews pop 20.20.001023000See
CHNChina Shandong Province0.10.00107418See
AUSAustralia West Caucasian0.10.0010891See
RUSRussia Samara Region0.00102500See
PRTPortugal Coimbra0.00105057See
PRTPortugal Evora0.0010737See
PRTPortugal Porto0.00107937See
PRTPortugal Viana do Castelo0.0010706See
PRTMadeira pop 30.0010538See
WALWales pop 20.10.001039979See
USAUSA OPTN Caucasian0.00108525See
INDIndia North pop 30.0009587See
ECUEcuador Andes Mixed Ancestry0.0006824See
POLPoland pop 30.10.00062907See
MEXMexico Tlaxcala Rural0.0006830See
MEXMexico Puebla Rural0.0006833See
ENGEngland Sheffield0.10.00054755See
ENGEngland Newcastle0.10.00052739See
ENGEngland Manchester0.10.00051640See
FRAFrance Marseille0.10.00051000See
SVKSlovakia pop 20.00054234See
ESPSpain, Castilla y Leon, Northwest,0.20.00051743See
CHNChina Shanghai0.000426266See
NORNorway ethnic Norwegians0.10.00044510See
RUSRussia Moscow Pop 20.10.00022000See
IRLIreland South pop 20.000117624See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA South Texas Hispanic0.0000194See
USAUSA OPTN Asian0.0000261See
SVNSlovenia pop 30.00.0000130See
SWESweden Stockholm0.10.00001347See
TWNTaiwan Chinese immigrants from North China0.0000152See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
TWNTaiwan Minnan pop 20.00007137See
TWNTaiwan Chinese immigrants from South China0.0000172See
HRVCroatia pop 20.0000100See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 10.0000324See
FRAFrance Rennes pop 30.0000200See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
CHNChina Harbin Korean0.0000201See
CHNChina North Han0.0000105See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina Jiangsu Province0.000020248See
CHNChina Yunnan Province Naxi0.0000118See
ENGEngland Leeds0.00.00005024See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ARGArgentina Corrientes0.00.0000155See
BRABrazil Parana Oriental0.00.000033See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
SCOScotland Orkney0.00.000099See
RUSRussia Moscow0.00002650See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal Portalegre0.00001254See
NIRIreland Northern0.00.00001000See
PRTPortugal Bragança0.0000301See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
MEXMexico Morelos, Cuernavaca0.000082See
MKDMacedonia pop 40.0000216See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Mexico City West0.000033See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mestizo0.00.000041See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Morelos Rural0.000030See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Mexico City Mestizo pop 30.0000256See
MEXMexico Baja California Rural0.000050See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Aguascalientes state0.000095See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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