Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 234 time(s) and present in 110 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Colima Rural0.034143See
MEXMexico Coahuila, Saltillo0.013772See
CMRCameroon Podokwo0.012043See
ZAFSouth Africa Tswana2.40.012041See
ESPSpain Minorca0.011094See
MEXMexico Chihuahua Rural0.0105236See
MEXMexico Nuevo Leon Rural0.0102439See
ITAItaly East Sicily2.00.010050See
TTOTrinidad African0.010067See
USAUSA OPTN African American0.01001510See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.010096See
MARMorocco pop 20.0090110See
GHAGhana Accre Asutuare Akan0.0090429See
MEXMexico Jalisco, Zapopan0.0089168See
PERPeru Arequipa Mestizo1.40.0070168See
TURTurkey pop 50.0070142See
MEXMexico Mexico City East0.006379See
MEXMexico Hidalgo Rural0.006281See
KURIraq Kurdistan Region1.00.0050209See
HRVCroatia pop 20.0050100See
BRABrazil REDOME Piaui0.004046140See
BRABrazil REDOME Bahia0.003947399See
MEXMexico Coahuila, Torreon0.0038396See
BRABrazil REDOME Maranhao0.003110180See
BRABrazil South Ribeirao Preto0.0030184See
BRABrazil Rio Grande do Norte Mestizo0.003012973See
ARGArgentina Corrientes0.60.0030155See
COLColombia Barranquilla0.0030188See
BRABrazil Parana Cafuzo0.60.0030319See
BRABrazil Parana Mixed race0.50.0030186See
BRABrazil Minas Gerais State Mixed0.60.00301000See
GAZGaza Palestinians0.0030165See
PRTPortugal Evora0.0030737See
AREUnited Arab Emirates pop 20.50.0030373See
PRTMadeira pop 30.0030538See
BRABrazil REDOME Acre0.0029859See
BRABrazil REDOME Paraiba0.002743868See
MEXMexico Veracruz, Xalapa0.0027187See
BRABrazil REDOME Espirito Santo0.002688485See
BRABrazil REDOME Rio de Janeiro0.0025139322See
BRABrazil REDOME Rio Grande do Norte0.002546603See
ITAItaly North Pavia pop 30.0025685See
BRABrazil REDOME Federal District0.002429549See
BRABrazil REDOME Pernambuco0.002492332See
BRABrazil REDOME Rondonia0.002454396See
BRABrazil Para Cord Blood Unit0.00.0024841See
BRABrazil REDOME Ceara0.0023101217See
BRABrazil REDOME Minas Gerais0.0022211275See
BRABrazil REDOME Tocantins0.002220692See
BRABrazil REDOME Para0.002172637See
MEXMexico Jalisco, Guadalajara city0.00211189See
BRABrazil REDOME Goias0.002088574See
ARGArgentina Cuyo Region0.50.0020420See
BRABrazil Rio Grande do Sul Black0.0020248See
BRABrazil South East Cord Blood0.002011409See
BRABrazil Para State0.20.00205000See
BRABrazil Parana Caucasian0.30.00202775See
PRTPortugal Bragança0.0020301See
ESPSpain, Castilla y Leon, Northwest,0.40.00201743See
BRABrazil REDOME Roraima0.00194140See
BRABrazil REDOME Mato Grosso0.001834649See
BRABrazil REDOME Sao Paulo0.0018800809See
ESPSpain Sevilla0.40.0018278See
MEXMexico Jalisco Rural0.0017585See
BRABrazil REDOME Mato Grosso do Sul0.001795667See
BRABrazil REDOME Amazonas0.001724129See
CHLChile Santiago0.0016920See
BRABrazil REDOME Alagoas0.001625349See
FRAFrance Marseille0.30.00161000See
MEXMexico Durango Rural0.0015326See
BRABrazil Rio Grande do Sul Mixed0.0015324See
BRABrazil REDOME Parana0.0013341639See
IRQIraq Erbil0.30.0013372See
BRABrazil REDOME Sergipe0.00127321See
BRABrazil REDOME Amapa0.001217864See
FRAFrance Grenoble0.20.00111000See
ARGArgentina Buenos Aires pop 20.50.00101216See
BRABrazil Sao Paulo Bauru Mixed0.00103542See
MEXMexico Oaxaca Rural0.0010485See
PRTPortugal Faro0.00101242See
PRTPortugal Porto0.00107937See
PRTPortugal Santarem0.00103865See
PRTPortugal Setubal0.00105268See
PRTPortugal Viana do Castelo0.0010706See
PRTPortugal Center pop 20.0010562See
PRTPortugal Aveiro0.00105933See
PRTPortugal Beja0.0010699See
PRTPortugal Braga0.00101971See
PRTPortugal Coimbra0.00105057See
ESPSpain Majorca0.0010407See
USAUSA OPTN Hispanic0.00101580See
PRTPortugal Leiria0.00101847See
PRTPortugal Lisbon0.001017420See
WALWales pop 20.00.001039979See
BRABrazil REDOME Rio Grande do Sul0.0009241329See
MEXMexico Puebla, Puebla city0.00081994See
BRABrazil Paraná Caucasian0.20.0008641See
BRABrazil REDOME Santa Catarina0.0007106673See
ECUEcuador Andes Mixed Ancestry0.0006824See
ISRIsrael Jews pop 20.10.000623000See
MEXMexico Puebla Rural0.0006833See
BRABrazil Rio Grande do Sul Caucasoid0.00054428See
ECUEcuador Mixed Ancestry0.00041173See
FRAFrance Lyon0.10.00044813See
ROMRomania pop 30.10.00031469See
GRCGreece pop 70.000111250See
GRCGreece North0.0000500See
IRNIran Royan Cord Blood Bank0.00.000015600See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly South Campania Region0.00.00001089See
KORSouth Korea pop 10.0000324See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
IRLIreland South pop 20.000017624See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MKDMacedonia pop 40.0000216See
MYSMalaysia pop 20.000062See
MEXMexico Mestizo0.00.000041See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Veracruz Rural0.0000539See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
ENGEngland Sheffield0.00.00004755See
CUBCuba Mixed Race0.00.000042See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
CHNChina Shanghai0.000026266See
CHNChina North Han0.0000105See
BRABrazil Sao Paulo Mixed0.00.0000239See
CMRCameroon Ewondo0.000038See
CMRCameroon Bamileke 20.000035See
CMRCameroon Uldeme0.000035See
BRABrazil Parana Afro Brazilian0.00.000077See
BRABrazil Parana Oriental0.00.000033See
AUSAustralia West Caucasian0.00.0000891See
BIHBosnia and Herzegovina0.0000134See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Rosario Toba0.00.000086See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
RUSRussia Northwest pop 30.00.0000100See
RUSRussia Moscow0.00002650See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
ZAFSouth Africa Natal Zulu0.00.0000100See
PRTPortugal Portalegre0.00001254See
PRTPortugal South pop 20.00001021See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
USAUSA OPTN Caucasian0.00008525See
USAUSA South Texas Hispanic0.0000194See
TTOTrinidad South Asian0.000087See
USAUSA OPTN Asian0.0000261See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Sinaloa Mestizo0.000056See
PAKPakistan Burusho0.000092See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Karachi Parsi0.000091See
PRTPortugal Vila Real0.00001167See
PRTPortugal Viseu0.00002915See
PRTPortugal Guarda0.0000797See
PRTPortugal Castelo Branco0.0000327See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional