Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 242 time(s) and present in 201 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MYSMalaysia Pahang Semai23.70.132038See
ISRIsrael Bukhara Jews0.12172317See
MYSMalaysia Kedah Kensiu23.80.119021See
INDIndia Mumbai Maratha0.086091See
ISRIsrael Kavkazi Jews0.08432840See
MYSMalaysia Kedah Baling Kensiu0.080025See
USAUSA NMDP Vietnamese0.079843540See
VNMVietnam Hanoi Kinh pop 20.0740170See
ISRIsrael Iraq Jews0.072713270See
GEOGeorgia Tibilisi Kurd0.069031See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
SGPSingapore Thai0.0610100See
CIVIvory Coast Adiopodoume Akan0.057044See
IDNIndonesia Java pop 20.042036See
LKASri Lanka Colombo8.30.0420714See
ZAFSouth Africa Natal Tamil0.041051See
MYSMalaysia Peninsular Indian7.40.0387271See
INDIndia Tamil Nadu0.03842492See
INDIndia North pop 20.038072See
ISRIsrael Iran Jews0.03458153See
SAUSaudi Arabia Guraiat and Hail6.80.0340213See
SGPSingapore Javaneses0.031051See
ISRIsrael Ashkenazi Jews pop 30.03044625See
CHNChina Yunnan Bulang0.0300116See
ISRIsrael YemenJews0.028215542See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0280146See
SENSenegal Niokholo Mandenka0.0270165See
TWNTaiwan Hakka5.50.027055See
ISRIsrael Libya Jews0.02693739See
IDNIndonesia Java Western5.10.0260236See
MYSMalaysia Peninsular Malay4.80.0252951See
ISRIsrael Tunisia Jews0.02519070See
USAUSA NMDP South Asian Indian0.0250185391See
USAUSA NMDP Filipino0.024650614See
CUBCuba Mixed Race4.80.024042See
GNBGuinea Bissau0.023065See
INDIndia Delhi pop 24.40.022090See
IDNIndonesia Sundanese and Javanese0.0220201See
USAUSA NMDP Southeast Asian0.021727978See
CHNChina Yunnan Province Wa0.0210119See
SGPSingapore Riau Malay0.0200132See
THAThailand pop 30.020049See
MYSMalaysia Perak Grik Jehai0.020025See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
CHNChina Guangzhou0.0200102See
PHLPhilippines Ivatan4.00.020050See
ZAFSouth Africa Natal Zulu4.00.0200100See
USAUSA Asian pop 20.01951772See
MYSMalaysia Mandailing3.70.019027See
CHESwitzerland Luzern0.01851553See
INDIndia West UCBB3.50.01745829See
CHNChina Canton Han0.0170264See
SGPSingapore Chinese Han0.017094See
SGPSingapore Chinese3.40.0170149See
CHESwitzerland Lausanne0.0164993See
CPVCape Verde Southeastern Islands0.016062See
CHNChina South Han0.0160284See
INDIndia New Delhi0.015071See
ISRIsrael Arab Druze0.0150101See
CHNChina Yunnan Province Han0.0150101See
IRNIran Baloch0.0150100See
USAUSA African American0.0140252See
USAUSA Asian0.0140358See
HKGHong Kong Chinese2.80.0140569See
CHESwitzerland Geneva pop 20.01321267See
ZAFSouth Africa Worcester3.00.0130159See
CMRCameroon Bamileke0.013077See
CHESwitzerland Graubunden0.0124759See
HKGHong Kong Chinese cord blood registry0.01233892See
SGPSingapore SGVP Malay MAS0.012089See
DEUGermany DKMS - Turkey minority0.01154856See
HKGHong Kong Chinese BMDR0.01117595See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
USAUSA Philadelphia Caucasian2.20.0110141See
ZMBZambia Lusaka0.011044See
ISRIsrael Arab pop 20.010512301See
USAUSA NMDP African0.010028557See
PRTPortugal Center0.010050See
INDIndia Andhra Pradesh Golla0.0100111See
USAUSA NMDP Middle Eastern or North Coast of Africa0.009970890See
INDIndia South UCBB2.00.009811446See
DEUGermany DKMS - China minority0.00941282See
CHNChina Jiangsu Province Han0.0088334See
CHESwitzerland Zurich0.00874875See
INDIndia Central UCBB1.70.00874204See
USAUSA NMDP Chinese0.008399672See
USAUSA NMDP African American pop 20.0082416581See
CPVCape Verde Northwestern Islands0.008062See
KORSouth Korea pop 30.0080485See
USAUSA African American pop 30.0080564See
USAUSA African American pop 80.0080605See
ISRIsrael Ethiopia Jews0.00785928See
KORSouth Korea pop 100.00744128See
USAUSA African American pop 40.00752411See
ISRIsrael Georgia Jews0.00744471See
INDIndia North UCBB1.50.00745849See
USAUSA NMDP Caribean Black0.007333328See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.40.00724335See
DEUGermany DKMS - Greece minority0.00711894See
GRCGreece pop 60.0071242See
MARMorocco Nador Metalsa pop 20.007073See
AREUnited Arab Emirates Pop 10.0070570See
CHESwitzerland Lugano0.00681169See
ISRIsrael Poland Jews0.006713871See
USAUSA NMDP Korean0.006677584See
DEUGermany DKMS - Spain minority0.00631107See
CHNChina Marrow Donor Registry0.0060600See
USAUSA NMDP Caribean Indian0.006014339See
CHESwitzerland St Gallen0.00552113See
DEUGermany DKMS - Portugal minority0.00551176See
DEUGermany DKMS - Romania minority0.00531234See
CHESwitzerland Sion0.0053832See
USAUSA NMDP Caribean Hispanic0.0053115374See
ISRIsrael USSR Jews0.005345681See
USAUSA NMDP Hawaiian or other Pacific Islander0.005211499See
USAUSA NMDP Hispanic South or Central American0.0052146714See
USAUSA Hispanic pop 20.00531999See
CHLChile Santiago Mixed1.00.005070See
CHNChina Inner Mongolia Region0.0050102See
CHNChina Yunnan Province Jinuo0.0050109See
GEOGeorgia Tibilisi0.0050109See
ESPSpain Andalusia Romani0.005099See
SDNSudan Mixed1.00.0050200See
USAUSA Eastern European0.0050558See
SRBSerbia pop 21.00.0050102See
USAUSA African American Bethesda1.10.0050187See
TWNTaiwan Minnan pop 11.00.0050102See
NZLNew Zealand Maori with Admixed History1.00.0050105See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
CHNChina Hubei Han1.00.00503732See
USAUSA San Diego1.00.0050496See
USAUSA NMDP Mexican or Chicano0.0049261235See
RUSRussia Bering Island Aleuts0.0048104See
DEUGermany DKMS - Italy minority0.00481159See
TZATanzania Maasai0.90.0045336See
PRTPortugal Azores Terceira Island0.90.0044130See
INDIndia East UCBB0.80.00422403See
DEUGermany pop 80.004039689See
ITAItaly pop 50.0040975See
TWNTaiwan Han Chinese0.0040504See
CHNChina Southwest Dai0.0040124See
CHNChina Beijing Shijiazhuang Tianjian Han0.0040618See
AUSAustralia New South Wales Caucasian0.0040134See
PRTAzores Terceira Island0.0040130See
USAUSA Caucasian Bethesda0.80.0040307See
FRAFrance Southeast0.80.0040130See
KENKenya Luo0.0040265See
USAUSA Hispanic0.0040234See
ISRIsrael USA Jews0.00386058See
GHAGhana Ga-Adangbe0.80.0038131See
CHESwitzerland Basel0.00381888See
COLColombia Bogotá Cord Blood0.70.00381463See
ISRIsrael Druze0.00365914See
ISRIsrael Morocco Jews0.003536718See
CZECzech Republic NMDR0.00345099See
NLDNetherlands Leiden0.00301305See
USAUSA NMDP American Indian South or Central America0.00305926See
USAUSA North American Native0.0030187See
CMRCameroon Beti0.0030174See
RUSRussia Tuva pop 20.0030169See
UGAUganda Kampala pop 20.0030175See
ENGEngland North West0.70.0030298See
USAUSA NMDP European Caucasian0.00301242890See
DEUGermany DKMS - Netherlands minority0.00291374See
CHNChina Jiangsu Han0.00283238See
DEUGermany DKMS - Austria minority0.00271698See
DEUGermany DKMS - German donors0.00273456066See
MYSMalaysia Peninsular Chinese0.50.0026194See
ISRIsrael Argentina Jews0.00264307See
POLPoland DKMS0.002520653See
DEUGermany DKMS - France minority0.00251406See
DEUGermany pop 60.00258862See
CHESwitzerland Bern0.00243545See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002246682See
HRVCroatia pop 40.00224000See
USAUSA NMDP North American Amerindian0.002135791See
USAUSA NMDP Alaska Native or Aleut0.00201376See
USAUSA San Francisco Caucasian0.0020220See
USAUSA European American pop 20.00201245See
KENKenya Nandi0.0020240See
USAUSA Caucasian pop 20.0020265See
DEUGermany DKMS - United Kingdom minority0.00191043See
USAUSA Caucasian pop 40.00191070See
DEUGermany DKMS - Croatia minority0.00152057See
MEXMexico Mexico City Tlalpan0.30.0015330See
TWNTaiwan pop 20.0010364See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
NIRIreland Northern0.10.00101000See
RUSRussia Karelia0.00091075See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
USAUSA NMDP Japanese0.000724582See
JPNJapan pop 160.000318604See
CHESwitzerland Aargau-Solothurn0.00001838See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP. Indian INS0.000086See
CHNChina Qinghai Province Hui0.0000110See
CHNChina Tibet Region Tibetan0.0000158See
INDIndia West Coast Parsi0.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Caucasian0.00.000070See
MEXMexico Mestizo0.00.000041See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
ITAItaly North pop 30.00.000097See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
CZECzech Republic0.0000106See
MARMorocco Settat Chaouya0.00.000098See
MLIMali Bandiagara0.0000138See
UGAUganda Kampala0.0000161See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See
CHNChina Beijing0.000067See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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