Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 413 time(s) and present in 385 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Bikaner Raikas49.60.2900143See
IRLIreland South pop 20.181017624See
GBRUnited Kingdom South West0.1704163See
PAKPakistan Burusho0.153092See
WALWales pop 227.80.150039979See
ENGEngland Sheffield27.30.14734755See
ENGEngland Liverpool27.30.14731343See
GBRUnited Kingdom Central0.1466135See
ENGEngland Newcastle26.80.14442739See
ENGEngland Leeds25.70.13805024See
ENGEngland Manchester25.40.13621640See
DEUGermany Essen25.30.1350174See
AUSAustralia West Caucasian24.70.1320891See
GBRUnited Kingdom East0.1304163See
FRAFrance Rennes pop 30.1300200See
ENGEngland Lancaster24.20.1293545See
GBRUnited Kingdom pop 20.1290101See
NORNorway ethnic Norwegians23.60.12754510See
NORNorway pop 20.1220576See
SWESweden pop 423.20.1211966See
ESPSpain Arratia Valley Basque0.120083See
PAKPakistan Mixed Sindhi0.1190101See
ENGEngland North West Mixed pop 223.50.1174379See
USAUSA Caucasian Bethesda22.50.1120307See
USAUSA OPTN Caucasian0.11208525See
SENSenegal Dakar20.50.1110112See
PAKPakistan Baloch0.108066See
PAKPakistan Brahui0.1060104See
SWESweden Uppsala20.00.1055300See
GBRUnited Kingdom North0.1045330See
SAUSaudi Arabia pop 419.50.1004499See
INDIndia Kerala Kurichiya0.100010See
POLPoland pop 319.60.09892907See
SDNSudan East Rashaida18.50.097227See
INDIndia Bikaner Non-Raikas18.40.0970127See
FRAFrance Rennes pop 419.30.09651000See
FRAFrance Grenoble, Nantes and Rennes0.09406094See
RUSRussia Arkhangelsk Pomor0.090063See
GBRUnited Kingdom Orkney0.089888See
SVKSlovakia pop 20.08934234See
FRAFrance Southeast16.90.0890130See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks16.10.0890112See
HRVCroatia pop 20.0880100See
SRBSerbia pop 316.50.08641992See
AREUnited Arab Emirates pop 216.40.0860373See
CMRCameroon Uldeme0.086035See
TUNTunisia Ghannouch0.085082See
SAUSaudi Arabia pop 20.0850383See
ESPSpain North Cabuerniga0.085095See
BIHBosnia and Herzegovina pop 216.70.0833120See
MEXMexico San Luis Potosi, San Luis Potosi city0.083330See
MEXMexico Morelos Rural0.083330See
FRAFrance Lyon16.40.08204813See
BIHBosnia and Herzegovina0.0820134See
SRBSerbia Vojvodina15.50.0810400See
MEXMexico Baja California, Tijuana0.080025See
ITAItaly Rome16.00.0800100See
FRAFrance Corsica Island0.0800100See
AUTAustria Cord Bloods0.07921368See
INDIndia Jalpaiguri Toto15.00.078040See
FRAFrance Reims0.0780102See
RUSRussia South Ural Russian15.50.0770207See
RUSRussia Northwest14.80.07691011See
FRAFrance Bordeaux15.20.0760990See
SVNSlovenia pop 314.60.0760130See
PRTMadeira pop 30.0760538See
FRAFrance Grenoble15.10.07551000See
HRVCroatia pop 315.00.0750120See
PRTPortugal Porto0.07407937See
PRTPortugal Aveiro0.07405933See
ESPSpain Majorca0.0740407See
PRTPortugal Coimbra0.07305057See
PRTPortugal Guarda0.0720797See
PRTPortugal Viana do Castelo0.0720706See
KURIraq Kurdistan Region12.40.0720209See
PRTPortugal Leiria0.07101847See
PRTPortugal Center pop 20.0710562See
PRTPortugal North pop 20.07081801See
RUSRussia Northwest pop 213.50.0700346See
ESPSpain Pas Valley0.070088See
FRAFrance Marseille13.80.06921000See
ROMRomania pop 313.10.06901469See
PRTPortugal Braga0.06901971See
MKDMacedonia MBMDR - Macedonian13.30.06901283See
MEXMexico Colima Rural0.068243See
RUSRussia Samara Region0.06802500See
PRTPortugal Vila Real0.06801167See
ESPSpain Ibiza0.068088See
BRABrazil Curitiba-Parana Mixed0.0679264See
IRQIraq Arabs13.40.0671149See
MKDMacedonia pop 30.0670172See
RUSRussia Moscow0.06702650See
RUSRussia North Ossetian12.60.0669127See
PAKPakistan Mixed Pathan0.0660100See
ARGArgentina Buenos Aires pop 212.90.06601216See
BRABrazil Parana Afro Brazilian13.00.065077See
PRTPortugal North0.065046See
ARGArgentina Buenos Aires12.40.0650466See
PRTPortugal Viseu0.06502915See
RUSRussia Moscow Pop 212.60.06462000See
BRABrazil REDOME Rio Grande do Sul0.0641241329See
PRTPortugal Faro0.06401242See
USAUSA African American Bethesda12.80.0640187See
PRTPortugal Castelo Branco0.0630327See
PRTPortugal Lisbon0.063017420See
PRTPortugal Portalegre0.06301254See
PRTPortugal Santarem0.06303865See
BRABrazil REDOME Santa Catarina0.0629106673See
MEXMexico Durango Rural0.0627326See
BRABrazil Rio Grande do Sul Caucasoid0.06204428See
PRTPortugal South pop 20.06201021See
CUBCuba Mixed0.062078See
ESPSpain, Castilla y Leon, Northwest,11.80.06141743See
PRTPortugal Setubal0.06105268See
ROMRomania pop 20.06006936See
ITAItaly pop 611.40.0598184See
BRABrazil REDOME Parana0.0564341639See
PRTPortugal Evora0.0560737See
ESPSpain Majorca and Minorca0.056090See
MEXMexico Veracruz, Poza Rica0.055645See
BRABrazil Parana Caucasian11.10.05502775See
ESPSpain Majorcans Jews0.0550103See
IRNIran pop 10.055064See
CZECzech Republic Romani pop 210.90.054446See
MEXMexico Sinaloa Mestizo0.054056See
NORNorway Sami0.0540200See
ARMArmenia Ghegharkunik0.0540242See
ESPSpain North Cantabria0.054083See
BRABrazil REDOME Minas Gerais0.0537211275See
BRABrazil REDOME Goias0.053188574See
MKDMacedonia pop 40.0530216See
ISRIsrael Ashkenazi Jews pop 20.0530132See
MEXMexico Coahuila Rural0.0528216See
VENVenezuela Colonia Tovar0.052386See
BRABrazil REDOME Espirito Santo0.052188485See
PRTPortugal Beja0.0520699See
ESPSpain Murcia0.0520173See
MNGMongolia Khalkha pop 20.0520202See
ESPSpain North10.00.0513156See
GTMGuatemala, Guatemala City Mixed Ancestry9.50.0512127See
ITAItaly Lombardy9.60.0510674See
BRABrazil REDOME Mato Grosso0.051034649See
RUSRussia Tatars0.0507355See
BRABrazil REDOME Sao Paulo0.0506800809See
ITAItaly North Pavia pop 30.0505685See
BRABrazil REDOME Rondonia0.050354396See
BRABrazil REDOME Rio de Janeiro0.0502139322See
BRABrazil Sao Paulo Bauru Mixed0.05003542See
ALBAlbanian Kosovo0.0500120See
BRABrazil Parana Cafuzo10.00.0500319See
ALBAlbania pop 210.00.0498432See
BRABrazil South Ribeirao Preto0.0490184See
ARMArmenia Lori0.0490102See
MEXMexico Mestizo pop 40.0483269See
BRABrazil REDOME Federal District0.048129549See
ARGArgentina Corrientes9.00.0480155See
PRTPortugal Bragança0.0480301See
ITAItaly North Pavia pop 29.20.04802416See
BRABrazil REDOME Mato Grosso do Sul0.047695667See
BRABrazil REDOME Alagoas0.047325349See
IRQIraq Erbil9.40.0471372See
MEXMexico Tlaxcala, Tlaxcala city0.0470181See
BRABrazil Minas Gerais State Mixed9.10.04701000See
MEXMexico Nayarit Rural0.046964See
MKDMacedonia MBMDR - Albanian9.40.0469128See
IRNIran pop 40.0468855See
MEXMexico Jalisco Rural0.0461585See
MARMorocco pop 20.0460110See
BRABrazil Rio Grande do Sul Black0.0460248See
BRABrazil Rio Grande do Sul Mixed0.0460324See
MARMorocco Casablanca0.0460100See
CUBCuba Mixed pop 20.0460189See
GRCGreece North0.0460500See
MEXMexico Guanajuato, Guanajuato city0.045522See
BRABrazil Paraná Caucasian9.00.0452641See
BRABrazil South East Cord Blood0.045211409See
MEXMexico Durango, Durango city0.0452153See
ENGEngland London Ashkenazi Jews0.0450500See
RUSRussia Northwest pop 38.00.0450100See
MEXMexico Guanajuato, Leon0.044978See
CHLChile Santiago0.0446920See
BRABrazil REDOME Tocantins0.044520692See
INDIndia North Gujarat7.70.0444338See
INDIndia Kerala Malabar Muslim0.044034See
BRABrazil REDOME Ceara0.0432101217See
BRABrazil Piaui Mixed0.043021943See
INDIndia North pop 30.0430587See
ITAItaly North Pavia0.043081See
USAUSA OPTN African American0.04301510See
GRCGreece Crete0.0430135See
PAKPakistan Kalash0.043069See
MEXMexico Zacatecas, Fresnillo0.0429103See
BRABrazil REDOME Rio Grande do Norte0.042846603See
BRABrazil REDOME Piaui0.042446140See
MEXMexico Aguascalientes state0.042195See
BRABrazil Rio Grande do Norte Mestizo0.042012973See
TURTurkey pop 50.0420142See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.042096See
ARGArgentina Cuyo Region8.20.0420420See
BRABrazil REDOME Paraiba0.041943868See
MEXMexico Chihuahua Rural0.0418236See
BRABrazil REDOME Sergipe0.04177321See
ESPSpain Sevilla7.90.0414278See
GRCGreece pop38.10.0413246See
MEXMexico Nayarit, Tepic0.041297See
MEXMexico Colima, Colima city0.041061See
MEXMexico Sinaloa Rural0.0410183See
BRABrazil REDOME Bahia0.040347399See
BRABrazil REDOME Maranhao0.040310180See
MEXMexico San Luis Potosi Rural0.040287See
BRABrazil REDOME Pernambuco0.040092332See
RUSRussia Murmansk Saomi Mixed0.040070See
BRABrazil REDOME Acre0.0396859See
ITAItaly South Campania Region7.70.03921089See
ISRIsrael Jews pop 27.60.039023000See
ARMArmenia Shirak0.039076See
MEXMexico Mexico City Mestizo pop 30.0390256See
MEXMexico Sonora, Ciudad Obregón0.0385143See
BRABrazil Parana Mixed race7.50.0380186See
ARGArgentina La Plata8.00.0380100See
ESPSpain Minorca0.038094See
MEXMexico Veracruz, Veracruz city0.0378171See
BRABrazil REDOME Amapa0.037717864See
GRCGreece pop 70.037711250See
RUSRussia South Ural Tatar7.40.0370135See
MEXMexico Mexico City Mestizo0.0370121See
RUSRussia Chuvash0.037082See
ZAFSouth Africa Tswana4.90.037041See
BRABrazil REDOME Roraima0.03624140See
BRABrazil REDOME Para0.036172637See
BRABrazil Sao Paulo Mixed0.70.0360239See
GEOGeorgia Kurds0.036030See
BRABrazil Para State6.80.03605000See
MEXMexico Veracruz, Cordoba0.035756See
DZAAlgeria pop 27.00.0356106See
MEXMexico Sonora, Hermosillo0.035499See
BRABrazil Para Cord Blood Unit6.90.0351841See
ESPSpain Andalusia0.035099See
MNGMongolia Khalkha0.0350200See
PRTAzores Terceira Island0.0350130See
TURTurkey pop 20.0350228See
BRABrazil Belem Mixed7.00.0350100See
MEXMexico Queretaro Rural0.034943See
COLColombia Barranquilla0.0345188See
MEXMexico Jalisco, Guadalajara city0.03431189See
MEXMexico Coahuila, Saltillo0.034272See
RUSRussia South Ural Bashkir6.80.0340146See
MEXMexico Coahuila, Torreon0.0338396See
BRABrazil REDOME Amazonas0.033124129See
TZATanzania Dodoma Kongwa0.0330212See
PAKPakistan Karachi Parsi0.033091See
MEXMexico Chihuahua, Ciudad Juarez0.0324106See
USAUSA OPTN Hispanic0.03201580See
ARMArmenia living in USA0.0320233See
MEXMexico Zacatecas Rural0.0316266See
MEXMexico Nuevo Leon, Monterrey city0.0310226See
ARMArmenia Yerevan0.0310445See
ARMArmenia Syunik0.0300117See
ARMArmenia living in Lebanon0.0300368See
IRNIran Royan Cord Blood Bank5.90.030015600See
VENVenezuela Caracas Mestizo0.030050See
ITAItaly East Sicily6.00.030050See
ECUEcuador Coast Mixed Ancestry0.0294238See
MEXMexico Veracruz, Xalapa0.0294187See
MEXMexico Chihuahua Chihuahua City0.0294119See
INDIndia Kerala Kattunaikka0.029017See
ARMArmenia living in Iran0.029085See
SAUSaudi Arabia5.60.028418See
MEXMexico Chiapas, Tuxtla Gutierrez0.028352See
ARMArmenia living in Karabakh0.0280445See
GAZGaza Palestinians0.0270165See
MEXMexico Baja California, La Paz0.026775See
MEXMexico Oaxaca Rural0.0267485See
MEXMexico Michoacan, Morelia0.0265150See
MEXMexico Oaxaca, Oaxaca city0.0265151See
MKDMacedonia MBMDR - Macedonian Muslims5.30.026376See
CMRCameroon Ewondo0.026038See
MEXMexico Yucatan, Merida0.0256192See
MEXMexico Veracruz, Orizaba0.025060See
MEXMexico Sinaloa Capomos Mayo Yoremes0.025060See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
INDIndia Kerala Hindu Namboothiri0.025040See
ITAItaly Sardinia pop30.0250100See
PERPeru Arequipa Mestizo4.70.0250168See
MEXMexico Michoacan Rural0.0244348See
MEXMexico Morelos, Cuernavaca0.024482See
ECUEcuador Mixed Ancestry0.02431173See
ECUEcuador Andes Mixed Ancestry0.0243824See
INDIndia Kerala Hindu Nair0.024041See
INDIndia Kerala Adiya0.024021See
MEXMexico Zacatecas, Zacatecas city0.023884See
MEXMexico Mexico City Center0.0227152See
ISRIsrael Moroccan Jews0.0220113See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
MEXMexico Guanajuato Rural0.0215162See
MEXMexico Campeche Rural0.021347See
MEXMexico Jalisco, Zapopan0.0208168See
MMRMyanmar Rakhine4.20.020848See
MEXMexico Nuevo Leon Rural0.0205439See
SDNSudan Khartoum0.020498See
RUSRussia Transbaikal Territory Buryats4.00.0200150See
MEXMexico Baja California Rural0.020050See
MEXMexico Baja Californa, Mexicali0.0200100See
MEXMexico Puebla Mestizo0.020099See
MYSMalaysia Sarawak Iban0.020051See
MEXMexico Tlaxcala Rural0.0199830See
MEXMexico Tamaulipas Rural0.0198125See
MEXMexico Sinaloa, Culiacán0.0194103See
BFABurkina Faso Mossi0.019053See
MEXMexico Yucatan Rural0.0187132See
MEXMexico Hidalgo Rural0.018581See
MMRMyanmar Shan3.70.018554See
GTMGuatemala Mayan0.0180132See
MEXMexico Veracruz, Coatzacoalcos0.017955See
MEXMexico Sonora Rural0.0178197See
MEXMexico Veracruz Rural0.0166539See
MEXMexico Chiapas Rural0.0165121See
INDIndia Kerala Syrian Christian0.016031See
LKASri Lanka Colombo Sinhalese0.0150101See
BRABrazil Pernambuco Mixed0.0150101See
MEXMexico Mayan Pop 30.015066See
MEXMexico Campeche, Campeche city0.014734See
MEXMexico Puebla Rural0.0144833See
MEXMexico Jalisco, Tonala0.014335See
MNGMongolia Tsaatan0.0140144See
CHNChina Shaanxi Province Han0.014010000See
CMRCameroon Bamileke 20.014035See
MEXMexico Guerrero state0.0139144See
CZECzech Republic Kurd2.70.013574See
SDNSudan Central Shaigiya Mixed2.70.013536See
MEXMexico Mexico City Metropolitan Area Rural0.0132150See
ECUEcuador Amazonia Mixed Ancestry0.012839See
MEXMexico Puebla, Puebla city0.01281994See
MEXMexico Mexico City East0.012579See
MEXMexico Hidalgo, Pachuca0.012241See
MEXMexico Tabasco, Villahermosa0.012282See
MEXMexico Mexico City North0.0120751See
COLColombia San Basilio de Palenque0.012042See
RUSRussia Nenet Mixed0.012055See
CHNChina Yunnan Province Han pop 20.0110129See
SDNSudan South Nuba2.20.011046See
CHNChina Shandong Province2.20.01107418See
BRABrazil Parana Japanese2.00.0105192See
MEXMexico Quintana Roo Rural0.010050See
CHNChina Jiangsu Province0.010020248See
USAUSA OPTN Asian0.0100261See
MNGMongolia Oold0.0100104See
TTOTrinidad South Asian0.010087See
INDIndia sub-Himalayan West Bengal Kami1.90.0095158See
TWNTaiwan Chinese immigrants from South China0.0090172See
CHNChina Guangdong Province1.70.0085403See
CHNChina Wuhan1.70.0080121See
CHNChina Shandong Province Linqu County1.50.0075139See
BOLBolivia Quechua0.007269See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
MEXMexico Tabasco Rural0.0070142See
TWNTaiwan Chinese immigrants from North China0.0070152See
CHNChina Shanghai0.007026266See
BGDBangladesh Dhaka Bangalee0.0070141See
CHNChina Harbin Manchu0.0060172See
BOLBolivia La Paz Aymaras0.006087See
THAThailand pop 40.005016807See
MYSMalaysia pop 30.00401445See
KORSouth Korea pop 10.0030324See
KORSouth Korea pop 80.00307096See
TWNTaiwan Chinese immigrants from Middle China0.0020211See
CHNChina Harbin Korean0.0020201See
THAThailand Northeast0.002066See
TWNTaiwan Minnan pop 20.00107137See
THAThailand Northeast pop 20.0010400See
CMRCameroon Podokwo0.000043See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
TTOTrinidad African0.000067See
MEXMexico Nahuas0.000072See
MEXMexico Huasteca Region Teenek0.000055See
ITAItaly North pop 30.00.000097See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
JPNJapan Hyogo Osaka and Nagano0.0000195See
BFABurkina Faso Rimaibe0.000047See
BFABurkina Faso Fulani0.000049See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
MYSMalaysia pop 20.000062See
CHNChina Yunnan Province Naxi0.0000118See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kuruma0.000015See
MEXMexico Mexico City West0.000033See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City South0.000052See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Queretaro, Queretaro city0.000045See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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