Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 289 time(s) and present in 265 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
IRLIreland South35.20.1820250See
AUSAustralia New South Wales Caucasian0.1730134See
NIRIreland Northern29.80.16201000See
ENGEngland North West29.90.1540298See
USAUSA San Francisco Caucasian0.1510220See
DEUGermany DKMS - United Kingdom minority0.13421043See
ZAFSouth Africa Caucasians0.1330102See
NLDNetherlands UMCU26.60.132864See
NLDNetherlands Leiden0.12801305See
USAUSA NMDP European Caucasian0.11441242890See
DEUGermany DKMS - Netherlands minority0.11251374See
USAUSA Caucasian Bethesda22.50.1120307See
USAUSA Caucasian pop 20.1090265See
DEUGermany pop 60.10368862See
CZECzech Republic NMDR0.10345099See
DEUGermany DKMS - German donors0.10213456066See
USAUSA Caucasian pop 40.10061070See
USAUSA European American pop 20.10001245See
AREUnited Arab Emirates Abu Dhabi0.096252See
FRAFrance French Bone Marrow Donor Registry0.095342623See
DEUGermany pop 80.095239689See
POLPoland DKMS0.095220653See
DEUGermany DKMS - Romania minority0.09481234See
USAUSA Eastern European0.0910558See
ESPSpain Gipuzkoa Basque0.0910100See
CHESwitzerland Lausanne0.0905993See
DEUGermany DKMS - Austria minority0.09011698See
FRAFrance Southeast16.90.0890130See
SCOScotland Orkney17.60.088099See
USAUSA San Antonio Caucasian0.0873222See
MARMorocco Nador Metalsa pop 20.087073See
INDIndia New Delhi0.083071See
USAUSA NMDP North American Amerindian0.082235791See
DEUGermany DKMS - Croatia minority0.08142057See
DEUGermany DKMS - France minority0.08141406See
CHESwitzerland Bern0.08113545See
AREUnited Arab Emirates Pop 10.0810570See
ESPSpain Andalusia Romani0.081099See
USAUSA NMDP American Indian South or Central America0.08005926See
SRBSerbia pop 215.70.0780102See
HRVCroatia pop 40.07784000See
DEUGermany DKMS - Portugal minority0.07781176See
DEUGermany DKMS - Bosnia and Herzegovina minority0.07731028See
GNBGuinea Bissau0.077065See
CHLChile Mapuche0.076966See
IRNIran Baloch0.0760100See
CHESwitzerland Geneva pop 20.07541267See
CHESwitzerland Sion0.0752832See
ZAFSouth Africa Natal Zulu14.00.0750100See
BRABrazil Belo Horizonte Caucasian13.70.074095See
CPVCape Verde Southeastern Islands0.073062See
USAUSA San Diego12.80.0720496See
DEUGermany DKMS - Spain minority0.07181107See
ZAFSouth Africa Natal Tamil0.071051See
SAUSaudi Arabia Guraiat and Hail13.20.0710213See
CHESwitzerland Graubunden0.0706759See
IRNIran Gorgan0.070064See
SWESweden Southern Sami0.0700130See
MEXMexico Mexico City Mestizo population0.0699143See
USAUSA NMDP Alaska Native or Aleut0.06901376See
GEOGeorgia Svaneti Region Svan0.069080See
ISRIsrael Tunisia Jews0.06809070See
USAUSA Philadelphia Caucasian13.30.0670141See
INDIndia Andhra Pradesh Golla0.0670111See
ZAFSouth Africa Worcester13.00.0660159See
PRTPortugal North0.065046See
USAUSA African American Bethesda12.80.0640187See
PRTAzores Oriental Islands0.064043See
STPSao Tome Island Angolar0.063032See
CHESwitzerland Lugano0.06281169See
MARMorocco Atlantic Coast Chaouya0.062098See
UGAUganda Kampala0.0620161See
MARMorocco Settat Chaouya12.40.062098See
INDIndia North UCBB12.10.06055849See
CHESwitzerland St Gallen0.06042113See
RUSRussia Karelia0.06031075See
RUSRussia Bering Island Aleuts0.0577104See
CHESwitzerland Luzern0.05711553See
CUBCuba Caucasian11.40.057070See
CHESwitzerland Basel0.05641888See
DEUGermany DKMS - Italy minority0.05611159See
CPVCape Verde Northwestern Islands0.056062See
CMRCameroon Yaounde0.054092See
USAUSA NMDP Middle Eastern or North Coast of Africa0.053670890See
CHNChina Uyghur HIV negative0.053019See
ITAItaly Bergamo9.90.0530101See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,10.40.05284335See
TUNTunisia Gabes0.052695See
CHESwitzerland Zurich0.05254875See
CZECzech Republic0.0520106See
MEXMexico Chihuahua Chihuahua City Pop 210.20.051188See
CHESwitzerland Aargau-Solothurn0.05061838See
DEUGermany DKMS - Greece minority0.05041894See
IRNIran Kurd pop 20.050060See
IRNIran Saqqez-Baneh Kurds0.050060See
CMRCameroon Baka Pygmy0.050010See
TZATanzania Maasai9.90.0494336See
ISRIsrael USSR Jews0.049445681See
ISRIsrael Libya Jews0.04923739See
SWESweden Northern Sami0.0490154See
ISRIsrael Georgia Jews0.04854471See
CUBCuba Mixed Race9.50.048042See
SENSenegal Niokholo Mandenka0.0480165See
ISRIsrael USA Jews0.04726058See
GRCGreece pop 60.0472242See
ISRIsrael Ashkenazi Jews pop 30.04704625See
USAUSA African American0.0460252See
KENKenya Nandi0.0460240See
ESPSpain Catalonia Girona0.046088See
BGRBulgaria Romani0.045013See
STPSao Tome Island Forro0.045066See
TUNTunisia pop 30.0450104See
USAUSA Hispanic pop 20.04451999See
ISRIsrael Poland Jews0.044513871See
UGAUganda Kampala pop 20.0430175See
BRABrazil Mixed0.0430108See
GRCGreece pop 87.20.042283See
USAUSA NMDP Mexican or Chicano0.0422261235See
USAUSA NMDP Caribean Hispanic0.0414115374See
ISRIsrael Argentina Jews0.04114307See
ITAItaly pop 50.0410975See
INDIndia Central UCBB8.20.04084204See
SDNSudan Mixed7.50.0400200See
USAUSA African American pop 30.0400564See
PRTPortugal Center0.040050See
DEUGermany DKMS - Turkey minority0.03924856See
INDIndia West UCBB7.80.03915829See
USAUSA NMDP Hispanic South or Central American0.0390146714See
USAUSA Hispanic0.0390234See
USAUSA South Texas Hispanic0.0390194See
USAUSA African American pop 40.03842411See
USAUSA African American pop 80.0380605See
JORJordan Amman0.0380146See
CMRCameroon Sawa0.038013See
USAUSA NMDP African American pop 20.0376416581See
USAUSA North American Native0.0370187See
USAUSA NMDP South Asian Indian0.0366185391See
IRNIran Yazd0.035756See
PRTPortugal Azores Terceira Island7.00.0351130See
USAUSA NMDP Caribean Indian0.035014339See
KENKenya, Nyanza Province, Luo tribe7.00.0350100See
PRTAzores Terceira Island0.0350130See
AUSAustralia Cape York Peninsula Aborigine0.0350103See
ZMBZambia Lusaka0.034044See
GEOGeorgia Tibilisi Kurd0.034031See
NZLNew Zealand Maori with Admixed History6.70.0330105See
USAUSA NMDP Southeast Asian0.032127978See
USAUSA NMDP African0.032028557See
COLColombia North Chimila Amerindians0.031947See
COLColombia Bogotá Cord Blood6.20.03181463See
INDIndia Tamil Nadu0.03112492See
SGPSingapore SGVP. Indian INS0.031086See
ZWEZimbabwe Harare Shona0.0310230See
IRNIran Tabriz Azeris0.030997See
MEXMexico Mexico City Tlalpan6.10.0303330See
KENKenya Luo0.0300265See
MEXMexico Oaxaca Zapotec0.030090See
INDIndia North pop 20.029072See
USAUSA NMDP Caribean Black0.028633328See
INDIndia South UCBB5.70.028611446See
ISRIsrael Morocco Jews0.028436718See
ISRIsrael Kavkazi Jews0.02692840See
ISRIsrael Arab pop 20.026112301See
ISRIsrael Druze0.02485914See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
MEXMexico Mestizo4.90.024041See
CIVIvory Coast Adiopodoume Akan0.023044See
NZLNew Zealand Maori with Full Ancestry4.30.022046See
USAUSA NMDP Hawaiian or other Pacific Islander0.021311499See
ISRIsrael Ethiopia Jews0.02035928See
CHLChile Santiago Mixed4.00.020270See
USAUSA South Dakota Lakota Sioux0.0200302See
PRTPortugal South0.020049See
AUSAustralia Groote Eylandt Aborigine0.020075See
ISRIsrael Iran Jews0.01928153See
INDIndia East UCBB3.80.01912403See
MYSMalaysia Mandailing3.70.019027See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
GEOGeorgia Tibilisi0.0190109See
ISRIsrael Iraq Jews0.019013270See
MYSMalaysia Peninsular Indian3.70.0185271See
ISRIsrael YemenJews0.018415542See
NICNicaragua Managua3.60.0181339See
PRTAzores Central Islands0.018059See
ARGArgentina Rosario Toba3.50.017086See
USAUSA Asian pop 20.01641772See
INDIndia Delhi pop 23.30.016090See
CHNChina Sichuan HIV negative0.015034See
MEXMexico Guadalajara Mestizo pop 20.0150103See
LKASri Lanka Colombo2.90.0150714See
CHNChina North Han0.0140105See
USAUSA Asian0.0130358See
SGPSingapore SGVP Chinese CHS0.011096See
CMRCameroon Beti0.0110174See
DEUGermany DKMS - China minority0.01091282See
CHNChina Yunnan Province Han0.0100101See
CMRCameroon Bakola Pygmy2.00.010050See
INDIndia West Coast Parsi0.010050See
TWNTaiwan Siraya2.00.010051See
ARMArmenia combined Regions0.0100100See
TWNTaiwan Hakka1.80.009055See
CHNChina Guangzhou Han0.0090106See
CHNChina Jiangsu Han0.00883238See
CHNChina Beijing0.008067See
RUSRussia Tuva pop 20.0080169See
MLIMali Bandiagara0.0070138See
CHNChina Beijing Shijiazhuang Tianjian Han0.0070618See
BRABrazil Puyanawa1.30.0070150See
INDIndia Northeast UCBB1.40.0068296See
MEXMexico Mexico City Mestizo pop 20.0064234See
USAUSA NMDP Filipino0.006250614See
MEXMexico Veracruz Xalapa1.20.006084See
CMRCameroon Bamileke0.006077See
USAUSA Arizona Pima0.0060100See
CHNChina Hubei Han1.10.00543732See
USAUSA NMDP Japanese0.005124582See
GHAGhana Accre Asutuare Akan0.0050429See
PERPeru Titikaka Lake Uros0.0050105See
SGPSingapore Thai0.0050100See
ISRIsrael Arab Druze0.0050101See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
PERPeru Titikaka Lake Uro0.0050105See
CHNChina Inner Mongolia Region0.0050102See
CHNChina Guangxi Region Maonan0.0050108See
CHNChina Guangzhou0.0050102See
KORSouth Korea pop 100.00484128See
USAUSA NMDP Vietnamese0.004843540See
USAUSA NMDP Korean0.004877584See
USAUSA NMDP Chinese0.004699672See
MYSMalaysia Peninsular Malay0.80.0042951See
KORSouth Korea pop 30.0040485See
USAUSA Alaska Yupik0.0040252See
TWNTaiwan pop 20.0040364See
CHNChina Southwest Dai0.0040124See
TWNTaiwan Han Chinese0.0040504See
CHNChina Jiangsu Province Han0.0034334See
ISRIsrael Bukhara Jews0.00322317See
HKGHong Kong Chinese BMDR0.00307595See
CHNChina Marrow Donor Registry0.0030600See
VNMVietnam Hanoi Kinh pop 20.0030170See
CHNChina Tibet Region Tibetan0.0030158See
HKGHong Kong Chinese0.50.0030569See
HKGHong Kong Chinese cord blood registry0.00303892See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002646682See
MYSMalaysia Peninsular Chinese0.50.0026194See
USAUSA Arizona Gila River Amerindian0.0020492See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
JPNJapan pop 160.000218604See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
SGPSingapore SGVP Malay MAS0.000089See
CHNChina Qinghai Province Hui0.0000110See
CAFCentral African Republic Mbenzele Pygmy0.00.000036See
MEXMexico Oaxaca Mixtec0.0000103See
SGPSingapore Chinese0.00.0000149See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Minnan pop 10.00.0000102See
AUSAustralia Yuendumu Aborigine0.0000191See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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