Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 221 time(s) and present in 180 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Wosera Abelam0.2830131See
TWNTaiwan Rukai52.00.280050See
AUSAustralia Cape York Peninsula Aborigine0.2700103See
TWNTaiwan Bunun45.50.2670101See
TWNTaiwan Paiwan45.10.255051See
AUSAustralia Yuendumu Aborigine0.2440191See
AUSAustralia Groote Eylandt Aborigine0.233075See
TWNTaiwan Thao40.00.217030See
CHNChina Guizhou Province Miao pop 20.211085See
MYSMalaysia Kedah Baling Kensiu0.200025See
CHNChina Guangxi Region Maonan0.1990108See
PNGPapua New Guinea Madang0.191065See
TWNTaiwan Tsou29.40.176051See
PNGPapua New Guinea Wanigela Keapara0.174066See
TWNTaiwan Puyuma32.00.170050See
CHNChina Yunnan Province Jinuo0.1610109See
TWNTaiwan pop 30.1440212See
MYSMalaysia Kedah Kensiu23.80.143021See
CHNChina Guizhou Province Shui0.1410153See
AUSAustralia Kimberly Aborigine0.132041See
PNGPapua New Guinea East New Britain Rabaul0.132060See
TWNTaiwan Siraya23.50.127051See
CHNChina Southwest Dai0.1250124See
INDIndia Khandesh Region Pawra0.120050See
TWNTaiwan Pazeh23.60.118055See
MYSMalaysia Champa20.70.103029See
CHNChina Guizhou Province Bouyei0.1030109See
CHNChina Guangzhou0.1000102See
SGPSingapore Thai0.0910100See
IRNIran Gorgan0.086064See
CHNChina Guangdong Province Meizhou Han0.0850100See
SGPSingapore Chinese16.80.0840149See
MYSMalaysia Jelebu Temuan0.083025See
CHNChina South Han0.0820284See
MYSMalaysia Perak Grik Jehai0.080025See
MYSMalaysia Peninsular Chinese16.00.0799194See
HKGHong Kong Chinese BMDR0.07947595See
HKGHong Kong Chinese15.40.0780569See
HKGHong Kong Chinese cord blood registry0.07753892See
NCLNew Caledonia0.077065See
SGPSingapore SGVP Chinese CHS0.075096See
TWNTaiwan Minnan pop 114.70.0740102See
NZLNew Zealand Polynesians with Full Ancestry14.30.071021See
PNGPapua New Guinea Karimui Plateau Pawaia0.069080See
CHNChina Canton Han0.0680264See
TWNTaiwan pop 20.0650364See
TWNTaiwan Hakka12.70.064055See
USAUSA NMDP Chinese0.063599672See
ZAFSouth Africa Natal Tamil0.061051See
PHLPhilippines Ivatan12.00.060050See
CHNChina Marrow Donor Registry0.0590600See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0579233See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.057057See
CHNChina Hubei Han11.40.05683732See
NZLNew Zealand Polynesians with Admixed History11.10.056027See
TWNTaiwan Han Chinese0.0560504See
SGPSingapore Riau Malay0.0540132See
TWNTaiwan Tzu Chi Morrow Donor Registry0.053846682See
TWNTaiwan Tzu Chi Cord Blood Bank0.0530710See
CHNChina Beijing0.053067See
CHNChina North Han0.0480105See
SGPSingapore Chinese Han0.047094See
CHNChina Yunnan Province Han0.0450101See
NZLNew Zealand Maori with Full Ancestry8.70.044046See
THAThailand pop 30.041049See
CHNChina Jiangsu Province Han0.0405334See
TWNTaiwan Tao8.00.040050See
USAUSA NMDP Vietnamese0.039443540See
VNMVietnam Hanoi Kinh pop 20.0380170See
MYSMalaysia Peninsular Malay7.30.0368951See
IRNIran Tabriz Azeris0.036197See
PNGPapua New Guinea West Schrader Ranges Haruai0.036055See
CHNChina Beijing Shijiazhuang Tianjian Han0.0360618See
DEUGermany DKMS - China minority0.03601282See
CHNChina Jiangsu Han0.03583238See
IRNIran Saqqez-Baneh Kurds0.033360See
IRNIran Kurd pop 20.033060See
USAUSA Asian0.0330358See
USAUSA Asian pop 20.03251772See
CHNChina Qinghai Province Hui0.0320110See
INDIndia West Coast Parsi0.030050See
SGPSingapore SGVP Malay MAS0.030089See
MYSMalaysia Peninsular Indian5.90.0295271See
INDIndia North pop 20.029072See
CHNChina Sichuan HIV negative0.029034See
TWNTaiwan Saisiat5.90.029051See
USAUSA NMDP Filipino0.028050614See
USAUSA NMDP Southeast Asian0.028027978See
IRNIran Yazd0.026856See
INDIndia Northeast UCBB5.10.0253296See
CHNChina Shanxi HIV negative0.023022See
INDIndia Tamil Nadu0.02202492See
USAUSA NMDP Korean0.021677584See
KORSouth Korea pop 100.02134128See
LKASri Lanka Colombo4.20.0210714See
JORJordan Amman0.0210146See
KORSouth Korea pop 30.0210485See
CHNChina Yunnan Province Wa0.0210119See
CHNChina Inner Mongolia Region0.0200102See
USAUSA NMDP Hawaiian or other Pacific Islander0.019911499See
INDIndia South UCBB3.90.019711446See
NZLNew Zealand Maori with Admixed History3.80.0190105See
FRAFrance Southeast3.80.0190130See
SGPSingapore SGVP. Indian INS0.019086See
SDNSudan East Rashaida3.70.018627See
MYSMalaysia Kelantan3.60.018028See
GEOGeorgia Tibilisi Kurd0.017031See
CHNChina Yunnan Hani0.0170150See
INDIndia East UCBB3.20.01582403See
JPNJapan Central0.0150371See
IDNIndonesia Sundanese and Javanese0.0150201See
CHNChina Jingpo Minority2.90.0150105See
INDIndia Andhra Pradesh Golla0.0140111See
IDNIndonesia Java pop 20.014036See
INDIndia Central UCBB2.80.01394204See
MEXMexico Mexico City Tlalpan2.70.0136330See
USAUSA NMDP South Asian Indian0.0136185391See
INDIndia West UCBB2.70.01355829See
JPNJapan pop 30.01301018See
JPNJapan pop 50.0130117See
MYSMalaysia Pahang Semai2.60.013038See
IDNIndonesia Java Western2.50.0130236See
SWESweden Southern Sami0.0120130See
JPNJapan pop 160.011718604See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
USAUSA NMDP Japanese0.011124582See
INDIndia North UCBB2.20.01105849See
INDIndia Delhi pop 22.20.011090See
ASMAmerican Samoa0.010051See
BRABrazil Puyanawa2.00.0100150See
SGPSingapore Javaneses0.010051See
USAUSA Hawaii Okinawa0.0100106See
TWNTaiwan Taroko1.80.009055See
CHNChina Yunnan Bulang0.0090116See
CHNChina Tibet Region Tibetan0.0090158See
INDIndia New Delhi0.008071See
NLDNetherlands UMCU1.60.007864See
MEXMexico Veracruz Xalapa1.20.006084See
RUSRussia Tuva pop 20.0060169See
CHESwitzerland Luzern0.00431553See
AREUnited Arab Emirates Pop 10.0040570See
USAUSA San Diego0.60.0030496See
NLDNetherlands Leiden0.00201305See
DEUGermany DKMS - Turkey minority0.00104856See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Eastern European0.0010558See
USAUSA Caucasian pop 40.00091070See
USAUSA Hispanic pop 20.00081999See
USAUSA NMDP Caribean Black0.000633328See
DEUGermany pop 80.000639689See
CZECzech Republic NMDR0.00065099See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000570890See
ISRIsrael Bukhara Jews0.00042317See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - Portugal minority0.00041176See
USAUSA African American pop 40.00042411See
ISRIsrael Ashkenazi Jews pop 30.00034625See
DEUGermany DKMS - Netherlands minority0.00041374See
DEUGermany DKMS - German donors0.00033456066See
ISRIsrael Arab pop 20.000212301See
ISRIsrael Morocco Jews0.000236718See
DEUGermany pop 60.00028862See
USAUSA NMDP North American Amerindian0.000235791See
ISRIsrael USSR Jews0.000245681See
USAUSA NMDP Hispanic South or Central American0.0002146714See
USAUSA NMDP Caribean Hispanic0.0001115374See
USAUSA NMDP African0.000128557See
ISRIsrael Iraq Jews0.000113270See
USAUSA NMDP Mexican or Chicano0.0001261235See
POLPoland DKMS0.000120653See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael Poland Jews0.000113871See
ISRIsrael Iran Jews0.00018153See
ISRIsrael YemenJews0.000015542See
ITAItaly pop 50.0000975See
INDIndia West Bhil0.000050See
INDIndia Mumbai Maratha0.000091See
NIRIreland Northern0.00.00001000See
JPNJapan Hokkaido Ainu0.000050See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
BRABrazil Belo Horizonte Caucasian0.00.000095See
AUSAustralia New South Wales Caucasian0.0000134See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
TWNTaiwan Ami0.00.000098See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
SDNSudan Mixed0.00.0000200See
TWNTaiwan Atayal0.00.0000106See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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