Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 309 time(s) and present in 280 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Jalpaiguri Toto32.50.178440See
PRTMadeira pop 20.1390173See
ESPSpain Ibiza0.131088See
ISRIsrael Ashkenazi Jews pop 20.1080132See
ESPSpain North Cantabria0.102083See
ENGEngland London Ashkenazi Jews0.1020500See
PRTMadeira pop 30.0980538See
PRTPortugal Bragança0.0950301See
ESPSpain Sevilla18.00.0935278See
CUBCuba Mixed0.093078See
ESPSpain North Cabuerniga0.092095See
USAUSA OPTN Caucasian0.09108525See
ESPSpain Minorca0.086094See
PRTPortugal Viana do Castelo0.0840706See
PRTPortugal Setubal0.08105268See
PRTPortugal Coimbra0.07905057See
PRTPortugal Evora0.0770737See
PRTPortugal Guarda0.0770797See
BRABrazil South Ribeirao Preto0.0770184See
PRTPortugal South pop 20.07701021See
CZECzech Republic Romani pop 215.20.076146See
PRTPortugal Santarem0.07603865See
ESPSpain Majorca and Minorca0.076090See
ITAItaly Sardinia pop30.0740100See
PRTPortugal Lisbon0.074017420See
PRTPortugal Faro0.07201242See
ISRIsrael Jews pop 213.70.072023000See
ESPSpain Murcia0.0710173See
PRTPortugal Leiria0.07101847See
PRTPortugal Portalegre0.07101254See
ARMArmenia living in USA0.0710233See
ARMArmenia living in Iran0.071085See
PRTPortugal North pop 20.07081801See
PRTPortugal Castelo Branco0.0700327See
PRTPortugal Beja0.0700699See
PRTPortugal Vila Real0.07001167See
PRTPortugal Braga0.06801971See
PRTPortugal Porto0.06807937See
GBRUnited Kingdom South West0.0675163See
ESPSpain North13.00.0672156See
BRABrazil Sao Paulo Mixed13.00.0670239See
PRTAzores Terceira Island0.0660130See
MKDMacedonia MBMDR - Macedonian Muslims13.20.065876See
PRTPortugal North0.065046See
ESPSpain Andalusia0.065099See
USAUSA African American Bethesda11.70.0640187See
PRTPortugal Aveiro0.06405933See
IRNIran pop 10.063064See
BRABrazil Rio Grande do Sul Mixed0.0630324See
ESPSpain, Castilla y Leon, Northwest,12.40.06201743See
ITAItaly Bergamo11.90.0620101See
ZAFSouth Africa Tswana12.20.061041See
COLColombia Barranquilla0.0610188See
BRABrazil Minas Gerais State Mixed12.20.06001000See
MEXMexico Mestizo pop 40.0595269See
BRABrazil REDOME Minas Gerais0.0591211275See
PRTPortugal Viseu0.05902915See
PRTPortugal Center pop 20.0590562See
IRLIreland South pop 20.058917624See
BRABrazil REDOME Federal District0.058729549See
BRABrazil Paraná Caucasian11.10.0585641See
BRABrazil REDOME Rio de Janeiro0.0582139322See
CUBCuba Mixed pop 20.0580189See
BRABrazil REDOME Pernambuco0.057792332See
BRABrazil REDOME Paraiba0.057443868See
SAUSaudi Arabia11.10.057118See
BRABrazil Rio Grande do Norte Mestizo0.057012973See
CMRCameroon Bamileke 20.057035See
BRABrazil REDOME Goias0.056688574See
DZAAlgeria pop 211.00.0566106See
BRABrazil REDOME Rio Grande do Norte0.056346603See
SDNSudan Khartoum0.056398See
BRABrazil REDOME Maranhao0.055910180See
BRABrazil REDOME Bahia0.055847399See
BRABrazil REDOME Alagoas0.055725349See
BRABrazil Belem Mixed11.00.0550100See
BRABrazil REDOME Rondonia0.054954396See
CHLChile Santiago0.0543920See
ARGArgentina Cuyo Region12.90.0540420See
BRABrazil South East Cord Blood0.054011409See
BRABrazil REDOME Ceara0.0531101217See
CMRCameroon Ewondo0.053038See
BRABrazil Piaui Mixed0.053021943See
MEXMexico Mayan Pop 30.053066See
BRABrazil REDOME Sao Paulo0.0524800809See
BRABrazil Rio Grande do Sul Caucasoid0.05204428See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.052096See
ESPSpain Catalonia Girona0.052088See
BRABrazil REDOME Mato Grosso do Sul0.051995667See
BRABrazil REDOME Mato Grosso0.051834649See
BRABrazil Sao Paulo Bauru Mixed0.05103542See
ARMArmenia Syunik0.0510117See
ARGArgentina Buenos Aires pop 210.10.05101216See
MEXMexico Mexico City Mestizo pop 30.0510256See
BRABrazil REDOME Piaui0.050346140See
ENGEngland Liverpool9.80.05021343See
FRAFrance Rennes pop 30.0500200See
VENVenezuela Zulia Maracaibo Mixed0.050020See
BRABrazil Pernambuco Mixed0.0500101See
BRABrazil REDOME Parana0.0500341639See
BRABrazil REDOME Sergipe0.05007321See
BRABrazil Para State9.30.05005000See
BRABrazil REDOME Tocantins0.049920692See
BRABrazil REDOME Amapa0.049417864See
BRABrazil REDOME Rio Grande do Sul0.0493241329See
SENSenegal Dakar9.80.0490112See
SCOScotland Orkney9.80.049099See
BRABrazil Rio Grande do Sul Black0.0480248See
BRABrazil REDOME Para0.048072637See
BRABrazil REDOME Acre0.0472859See
FRAFrance Southeast9.20.0470130See
BRABrazil REDOME Espirito Santo0.046988485See
BRABrazil REDOME Roraima0.04694140See
BRABrazil REDOME Santa Catarina0.0467106673See
FRAFrance Rennes pop 49.20.04671000See
BRABrazil REDOME Amazonas0.045824129See
USAUSA OPTN Hispanic0.04501580See
BRABrazil Parana Oriental9.10.045033See
FRAFrance Marseille8.90.04461000See
ARMArmenia Lori0.0440102See
FRAFrance Lyon8.60.04354813See
ENGEngland Manchester8.50.04341640See
FRAFrance Grenoble, Nantes and Rennes0.04306094See
GRCGreece Crete0.0430135See
USAUSA Caucasian Bethesda8.60.0430307See
ESPSpain Majorca0.0430407See
ENGEngland Newcastle8.40.04292739See
BRABrazil Parana Cafuzo8.40.0420319See
ARGArgentina La Plata9.00.0420100See
ARGArgentina Buenos Aires8.30.0420466See
GAZGaza Palestinians0.0420165See
MEXMexico Sinaloa Capomos Mayo Yoremes0.041760See
ENGEngland North West Mixed pop 27.70.0409379See
RUSRussia Northwest pop 38.00.0400100See
ITAItaly East Sicily8.00.040050See
ARMArmenia living in Karabakh0.0400445See
BRABrazil Parana Mixed race8.00.0400186See
FRAFrance Bordeaux7.70.0395990See
ITAItaly North Pavia pop 30.0394685See
ARMArmenia Ghegharkunik0.0390242See
ITAItaly Lombardy7.60.0390674See
WALWales pop 27.70.039039979See
ENGEngland Lancaster7.50.0382545See
ESPSpain Pas Valley0.038088See
ARMArmenia living in Lebanon0.0380368See
GBRUnited Kingdom Central0.0376135See
FRAFrance Grenoble7.40.03751000See
GRCGreece pop37.30.0371246See
ENGEngland Leeds7.30.03715024See
MARMorocco Casablanca0.0370100See
ITAItaly North Pavia pop 27.20.03702416See
MMRMyanmar Shan7.40.037054See
MARMorocco pop 20.0360110See
ISRIsrael Moroccan Jews0.0360113See
BRABrazil Parana Caucasian7.20.03602775See
GBRUnited Kingdom Orkney0.035988See
BRABrazil Para Cord Blood Unit6.90.0357841See
GBRUnited Kingdom pop 20.0350101See
HRVCroatia pop 20.0340100See
ENGEngland Sheffield6.50.03304755See
AUSAustralia West Caucasian6.40.0330891See
SRBSerbia Vojvodina6.50.0330400See
TZATanzania Dodoma Kongwa0.0330212See
BRABrazil Curitiba-Parana Mixed0.0329264See
ITAItaly pop 66.00.0326184See
SRBSerbia pop 36.20.03161992See
GBRUnited Kingdom East0.0311163See
BFABurkina Faso Fulani0.031049See
USAUSA OPTN African American0.03001510See
ITAItaly Rome6.00.0300100See
ARMArmenia Yerevan0.0300445See
MYSMalaysia Negeri Sembilan Minangkabau0.030034See
IRNIran pop 40.0292855See
VENVenezuela Colonia Tovar0.029186See
IRNIran Royan Cord Blood Bank5.60.028015600See
MEXMexico Tapachula, Chiapas Mestizo Population5.60.028072See
RUSRussia Northwest5.50.02781011See
GRCGreece pop 70.027711250See
GBRUnited Kingdom North0.0276330See
RUSRussia Moscow0.02702650See
CZECzech Republic Kurd5.40.027074See
NORNorway pop 20.0270576See
RUSRussia Samara Region0.02702500See
RUSRussia Moscow Pop 25.30.02652000See
ARMArmenia Shirak0.026076See
ARGArgentina Corrientes6.40.0260155See
ROMRomania pop 35.10.02531469See
ESPSpain Gipuzkoa Basque0.0250100See
GRCGreece North0.0250500See
PAKPakistan Mixed Sindhi0.0250101See
ITAItaly South Campania Region4.80.02431089See
TURTurkey pop 50.0240142See
PERPeru Lamas City Lama0.024083See
SWESweden Uppsala4.70.0237300See
BOLBolivia La Paz Aymaras0.023087See
ESPSpain Majorcans Jews0.0220103See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks4.50.0220112See
KURIraq Kurdistan Region4.30.0220209See
NORNorway ethnic Norwegians4.30.02174510See
SVKSlovakia pop 20.02134234See
RUSRussia Northwest pop 24.20.0210346See
FRAFrance Corsica Island0.0210100See
SAUSaudi Arabia pop 44.00.0201499See
ROMRomania pop 20.02006936See
KORSouth Korea pop 10.0200324See
RUSRussia Arkhangelsk Pomor0.020063See
VENVenezuela Caracas Mestizo0.020050See
ESPSpain Arratia Valley Basque0.020083See
SWESweden pop 43.80.0197966See
MKDMacedonia MBMDR - Macedonian3.80.01911283See
GHAGhana Accre Asutuare Akan0.0190429See
BRABrazil Parana Afro Brazilian3.90.019077See
IRQIraq Erbil3.80.0188372See
GTMGuatemala Mayan0.0180132See
RUSRussia Chuvash0.018082See
POLPoland pop 33.60.01782907See
RUSRussia South Ural Russian3.40.0170207See
PERPeru Arequipa Mestizo3.40.0170168See
INDIndia Kerala Syrian Christian0.016031See
RUSRussia Tatars0.0154355See
AREUnited Arab Emirates pop 22.90.0150373See
MEXMexico Michoacan Tarasco3.00.0150130See
PAKPakistan Brahui0.0140104See
BIHBosnia and Herzegovina pop 22.50.0125120See
HRVCroatia pop 32.50.0125120See
SVNSlovenia pop 32.30.0120130See
KORSouth Korea pop 80.01207096See
COLColombia San Basilio de Palenque0.012042See
BIHBosnia and Herzegovina0.0111134See
BRABrazil Parana Japanese2.00.0105192See
IRQIraq Arabs2.00.0101149See
RUSRussia South Ural Bashkir2.10.0100146See
RUSRussia Murmansk Saomi Mixed0.010070See
USAUSA OPTN Asian0.0100261See
SAUSaudi Arabia pop 20.0090383See
BFABurkina Faso Mossi0.009053See
ARGArgentina Chiriguano1.90.009054See
MKDMacedonia pop 30.0090172See
MKDMacedonia pop 40.0090216See
ALBAlbania pop 21.60.0081432See
RUSRussia Nenet Mixed0.008055See
BOLBolivia Quechua0.007269See
CHNChina Harbin Korean0.0070201See
CHNChina Shandong Province1.50.00707418See
CHNChina Shaanxi Province Han0.007010000See
CHNChina Harbin Manchu0.0060172See
MEXMexico Nahuas0.006072See
MNGMongolia Khalkha pop 20.0050202See
PAKPakistan Mixed Pathan0.0050100See
MYSMalaysia pop 20.004062See
RUSRussia South Ural Tatar0.70.0040135See
RUSRussia North Ossetian0.80.0039127See
MKDMacedonia MBMDR - Albanian0.80.0039128See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
TWNTaiwan Chinese immigrants from North China0.0030152See
INDIndia North Gujarat0.60.0030338See
INDIndia North pop 30.0020587See
CHNChina Jiangsu Province0.002020248See
CHNChina Guangdong Province0.30.0015403See
MYSMalaysia pop 30.00101445See
JPNJapan pop 20.0010916See
TWNTaiwan Hakka pop 20.0010714See
THAThailand pop 40.001016807See
CHNChina Shanghai0.000926266See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
JPNJapan Tohoku Region0.0000322See
BFABurkina Faso Rimaibe0.000047See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Hindu Nair0.000041See
JPNJapan Hyogo Osaka and Nagano0.0000195See
TWNTaiwan Aborigine0.0000111See
MEXMexico Huasteca Region Teenek0.000055See
TWNTaiwan Minnan pop 20.00007137See
TWNTaiwan Chinese immigrants from South China0.0000172See
TWNTaiwan Chinese immigrants from Middle China0.0000211See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
ARGArgentina Salta Wichi pop 20.00.000019See
NORNorway Sami0.0000200See
MYSMalaysia Perak Rawa0.000023See
CMRCameroon Uldeme0.000035See
CMRCameroon Podokwo0.000043See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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