Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 336 time(s) and present in 298 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico San Luis Potosi, San Luis Potosi city0.116730See
MEXMexico Jalisco, Tonala0.114335See
ISRIsrael Argentina Jews0.10544307See
ISRIsrael Ashkenazi Jews pop 30.10424625See
ISRIsrael Poland Jews0.101313871See
ISRIsrael USA Jews0.10006058See
PAKPakistan Karachi Parsi0.099091See
CPVCape Verde Southeastern Islands0.097062See
MEXMexico Jalisco, Zapopan0.0804168See
MEXMexico Nayarit Rural0.078164See
MEXMexico Guadalajara Mestizo pop 20.0780103See
ISRIsrael USSR Jews0.076545681See
ISRIsrael Ethiopia Jews0.07635928See
ISRIsrael Kavkazi Jews0.07482840See
MEXMexico Hidalgo, Pachuca0.073241See
MEXMexico Sonora, Ciudad Obregón0.0699143See
ITAItaly North pop 313.30.067097See
MEXMexico Jalisco, Tlajomulco0.066730See
MEXMexico Baja Californa, Mexicali0.0650100See
PRTPortugal North0.065046See
MEXMexico Sinaloa, Culiacán0.0631103See
MEXMexico Sinaloa Mestizo0.063056See
ISRIsrael YemenJews0.061915542See
MEXMexico Mexico City Center0.0617152See
MEXMexico Guanajuato Rural0.0614162See
MEXMexico Quintana Roo Rural0.060050See
MEXMexico Baja California, Tijuana0.060025See
ARMArmenia combined Regions0.0600100See
MEXMexico Zacatecas, Zacatecas city0.059584See
MEXMexico Oaxaca Mixtec0.0590103See
MEXMexico Veracruz, Orizaba0.058360See
USAUSA African American Bethesda10.60.0580187See
CUBCuba Caucasian11.40.057070See
PRTPortugal Azores Terceira Island11.40.0570130See
ITAItaly pop 50.0570975See
MEXMexico Colima Rural0.056843See
MEXMexico Michoacan Rural0.0544348See
MEXMexico Mexico City Mestizo0.0540121See
PRTAzores Central Islands0.054059See
MEXMexico Campeche Rural0.053247See
BRABrazil Belo Horizonte Caucasian10.50.053095See
ISRIsrael Druze0.05255914See
PRTAzores Terceira Island0.0510130See
PRTAzores Oriental Islands0.051043See
MEXMexico Sonora, Hermosillo0.050599See
MEXMexico Baja California Rural0.050050See
MEXMexico Mestizo9.80.049041See
DEUGermany DKMS - Portugal minority0.04891176See
MEXMexico Coahuila Rural0.0482216See
TUNTunisia Gabes0.047395See
MEXMexico Nayarit, Tepic0.046497See
MEXMexico Chihuahua Chihuahua City0.0462119See
USAUSA San Francisco Caucasian0.0460220See
NICNicaragua Managua8.70.0452339See
USAUSA San Antonio Caucasian0.0452222See
DEUGermany DKMS - Spain minority0.04521107See
MEXMexico Jalisco, Guadalajara city0.04481189See
USAUSA NMDP Hispanic South or Central American0.0441146714See
FRAFrance Reims0.0440102See
SRBSerbia pop 28.80.0440102See
ISRIsrael Bukhara Jews0.04382317See
MEXMexico Sonora Rural0.0431197See
USAUSA Caucasian Bethesda8.60.0430307See
KENKenya Luo0.0430265See
USAUSA NMDP Mexican or Chicano0.0428261235See
MARMorocco Atlantic Coast Chaouya0.041098See
MEXMexico Colima, Colima city0.041061See
MARMorocco Settat Chaouya8.40.041098See
USAUSA Hispanic0.0410234See
USAUSA Hispanic pop 20.04101999See
ISRIsrael Tunisia Jews0.04019070See
PRTPortugal Center0.040050See
COLColombia Bogotá Cord Blood7.90.04001463See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.90.03994335See
USAUSA NMDP Caribean Hispanic0.0390115374See
MEXMexico Yucatan, Merida0.0385192See
MEXMexico Zacatecas, Fresnillo0.0381103See
MEXMexico Mexico City East0.037579See
UGAUganda Kampala0.0370161See
USAUSA NMDP Middle Eastern or North Coast of Africa0.036170890See
MARMorocco Nador Metalsa pop 20.036073See
NIRIreland Northern7.00.03601000See
ISRIsrael Morocco Jews0.035736718See
MEXMexico Chihuahua Rural0.0356236See
CHLChile Santiago Mixed7.00.035670See
GTMGuatemala, Guatemala City Mixed Ancestry6.30.0354127See
ESPSpain Andalusia Romani0.035099See
MEXMexico Puebla Mestizo0.035099See
FRAFrance Southeast6.90.0350130See
ZMBZambia Lusaka0.034044See
USAUSA Caucasian pop 20.0340265See
USAUSA San Diego6.10.0340496See
MEXMexico Coahuila, Torreon0.0338396See
USAUSA Caucasian pop 40.03351070See
MEXMexico Zacatecas Rural0.0335266See
MEXMexico Mexico City Tlalpan6.70.0333330See
MEXMexico Baja California, La Paz0.033375See
MEXMexico Veracruz, Poza Rica0.033345See
MEXMexico Chiapas Rural0.0331121See
MEXMexico Sinaloa Rural0.0328183See
MEXMexico Durango, Durango city0.0323153See
MEXMexico Mexico City Mestizo pop 20.0321234See
USAUSA NMDP Caribean Indian0.032014339See
CPVCape Verde Northwestern Islands0.032062See
ISRIsrael Arab pop 20.031512301See
FRAFrance French Bone Marrow Donor Registry0.031442623See
DEUGermany DKMS - Italy minority0.03151159See
MEXMexico Veracruz Rural0.0314539See
UGAUganda Kampala pop 20.0310175See
ITAItaly North Pavia0.031081See
PRTPortugal South0.031049See
ECUEcuador Andes Mixed Ancestry0.0309824See
CHLChile Mapuche0.030866See
ECUEcuador Mixed Ancestry0.03071173See
KENKenya, Nyanza Province, Luo tribe6.00.0300100See
USAUSA South Texas Hispanic0.0300194See
USAUSA Eastern European0.0300558See
CHESwitzerland Lugano0.02991169See
MEXMexico Mexico City West0.029933See
MEXMexico Oaxaca, Oaxaca city0.0298151See
CHESwitzerland Geneva pop 20.02931267See
AREUnited Arab Emirates Abu Dhabi0.028852See
USAUSA NMDP European Caucasian0.02861242890See
CHESwitzerland Basel0.02811888See
DEUGermany DKMS - France minority0.02811406See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0280146See
MEXMexico Coahuila, Saltillo0.027472See
MEXMexico Jalisco Rural0.0273585See
SENSenegal Niokholo Mandenka0.0270165See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02631028See
USAUSA NMDP American Indian South or Central America0.02605926See
ECUEcuador Amazonia Mixed Ancestry0.025639See
ECUEcuador Coast Mixed Ancestry0.0252238See
CHESwitzerland Sion0.0252832See
ZAFSouth Africa Natal Zulu5.00.0250100See
MEXMexico Mexico City North0.0246751See
MEXMexico Puebla, Puebla city0.02451994See
MEXMexico Durango Rural0.0245326See
MEXMexico Mexico City Mestizo population0.0245143See
CUBCuba Mixed Race4.80.024042See
IRLIreland South4.80.0240250See
ZWEZimbabwe Harare Shona0.0240230See
JORJordan Amman0.0240146See
DEUGermany DKMS - Romania minority0.02391234See
MEXMexico Nuevo Leon Rural0.0239439See
MEXMexico Tamaulipas Rural0.0238125See
MEXMexico Queretaro Rural0.023343See
TUNTunisia pop 30.0230104See
USAUSA European American pop 20.02301245See
CIVIvory Coast Adiopodoume Akan0.023044See
CMRCameroon Beti0.0230174See
MEXMexico Puebla Rural0.0228833See
MEXMexico Guanajuato, Guanajuato city0.022722See
MEXMexico Queretaro, Queretaro city0.022245See
MEXMexico Nuevo Leon, Monterrey city0.0221226See
DEUGermany DKMS - Turkey minority0.02214856See
BRABrazil Mixed0.0220108See
USAUSA Philadelphia Caucasian4.40.0220141See
USAUSA African American pop 40.02202411See
USAUSA NMDP African0.021928557See
DEUGermany DKMS - Austria minority0.02181698See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
USAUSA NMDP African American pop 20.0216416581See
DEUGermany DKMS - United Kingdom minority0.02161043See
MEXMexico Veracruz, Xalapa0.0214187See
USAUSA NMDP Caribean Black0.021233328See
HRVCroatia pop 40.02124000See
MEXMexico Aguascalientes state0.021195See
ZAFSouth Africa Caucasians0.0210102See
SAUSaudi Arabia pop 6 (G)0.020928927See
MEXMexico Guerrero state0.0208144See
USAUSA NMDP North American Amerindian0.020435791See
MEXMexico Veracruz, Veracruz city0.0203171See
ISRIsrael Arab Druze0.0200101See
MEXMexico Michoacan, Morelia0.0199150See
DEUGermany pop 80.019839689See
MEXMexico Guanajuato, Leon0.019278See
GEOGeorgia Svaneti Region Svan0.019080See
DEUGermany DKMS - Greece minority0.01901894See
MEXMexico Chihuahua, Ciudad Juarez0.0185106See
DEUGermany DKMS - German donors0.01833456066See
ISRIsrael Libya Jews0.01833739See
MEXMexico Tabasco, Villahermosa0.018382See
DEUGermany pop 60.01808862See
USAUSA African American pop 80.0180605See
SDNSudan Mixed3.50.0180200See
USAUSA African American0.0180252See
MEXMexico Veracruz, Cordoba0.017956See
CHESwitzerland Graubunden0.0177759See
MEXMexico Oaxaca Rural0.0175485See
RUSRussia Karelia0.01731075See
MEXMexico San Luis Potosi Rural0.017287See
MEXMexico Chihuahua Chihuahua City Pop 23.40.017088See
DEUGermany DKMS - Croatia minority0.01682057See
GRCGreece pop 60.0165242See
CZECzech Republic NMDR0.01655099See
MEXMexico Mixtec0.016097See
ZAFSouth Africa Worcester3.00.0160159See
MEXMexico Oaxaca Jamiltepec Mixtec0.016096See
IRNIran Gorgan0.016064See
CHESwitzerland Lausanne0.0157993See
GHAGhana Ga-Adangbe3.10.0153131See
SAUSaudi Arabia Guraiat and Hail2.90.0150213See
USAUSA South Dakota Lakota Sioux0.0150302See
IRNIran Baloch0.0150100See
GNBGuinea Bissau0.015065See
CHESwitzerland Zurich0.01494875See
CHESwitzerland St Gallen0.01482113See
MEXMexico Campeche, Campeche city0.014734See
RUSRussia Bering Island Aleuts0.0144104See
USAUSA NMDP Alaska Native or Aleut0.01401376See
NLDNetherlands Leiden0.01401305See
GEOGeorgia Tibilisi0.0140109See
POLPoland DKMS0.014120653See
DEUGermany Essen2.90.0140174See
CZECzech Republic0.0140106See
DEUGermany DKMS - Netherlands minority0.01381374See
MEXMexico Tlaxcala, Tlaxcala city0.0138181See
MEXMexico Tlaxcala Rural0.0133830See
USAUSA North American Native0.0130187See
ISRIsrael Iraq Jews0.012713270See
MEXMexico Hidalgo Rural0.012381See
CHESwitzerland Bern0.01223545See
MEXMexico Morelos, Cuernavaca0.012282See
AREUnited Arab Emirates pop 22.40.0120373See
TZATanzania Maasai2.40.0120336See
ISRIsrael Iran Jews0.01148153See
MLIMali Bandiagara0.0110138See
AUSAustralia New South Wales Caucasian0.0110134See
COLColombia North Chimila Amerindians0.010647See
MEXMexico Quintana Roo, Cancun0.010448See
NZLNew Zealand Maori with Admixed History1.90.0100105See
THAThailand pop 30.010049See
BRABrazil Puyanawa2.00.0100150See
AREUnited Arab Emirates Pop 10.0100570See
COLColombia North Wiwa El Encanto0.009652See
MEXMexico Chiapas, Tuxtla Gutierrez0.009452See
MEXMexico Chiapas Lacandon Mayans0.0092218See
USAUSA NMDP Hawaiian or other Pacific Islander0.009211499See
CHNChina Qinghai Province Hui0.0090110See
MEXMexico Oaxaca Mixe0.009055See
IRNIran Yazd0.008956See
CHESwitzerland Aargau-Solothurn0.00811838See
STPSao Tome Island Forro0.008066See
NLDNetherlands UMCU1.60.007864See
CHESwitzerland Luzern0.00751553See
MEXMexico Yucatan Rural0.0075132See
MEXMexico Oaxaca Zapotec0.007090See
MKDMacedonia pop 40.0070216See
MEXMexico Mexico City Metropolitan Area Rural0.0066150See
SGPSingapore SGVP. Indian INS0.006086See
KENKenya Nandi0.0060240See
CMRCameroon Bamileke0.006077See
SGPSingapore Chinese Han0.006094See
GRCGreece pop 81.20.006083See
ISRIsrael Georgia Jews0.00504471See
CMRCameroon Yaounde0.005092See
CHNChina North Han0.0050105See
DEUGermany DKMS - China minority0.00511282See
PAKPakistan Mixed Sindhi0.0050101See
MEXMexico Tabasco Rural0.0035142See
USAUSA NMDP Filipino0.002950614See
USAUSA NMDP Southeast Asian0.002627978See
CHNChina Hubei Han0.50.00233732See
USAUSA NMDP South Asian Indian0.0017185391See
CHNChina Jiangsu Han0.00173238See
USAUSA NMDP Japanese0.001224582See
USAUSA Asian pop 20.00111772See
INDIndia West UCBB0.20.00105829See
INDIndia Tamil Nadu0.00102492See
LKASri Lanka Colombo0.30.0010714See
CHNChina Marrow Donor Registry0.0010600See
USAUSA NMDP Chinese0.001099672See
INDIndia North UCBB0.20.00095849See
INDIndia South UCBB0.10.000711446See
INDIndia Central UCBB0.10.00064204See
MYSMalaysia Peninsular Malay0.10.0005951See
USAUSA NMDP Vietnamese0.000443540See
HKGHong Kong Chinese cord blood registry0.00033892See
USAUSA NMDP Korean0.000277584See
INDIndia East UCBB0.00.00022403See
KORSouth Korea pop 100.00024128See
HKGHong Kong Chinese BMDR0.00027595See
JPNJapan pop 160.000118604See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Mexico City South0.000052See
MEXMexico Veracruz, Coatzacoalcos0.000055See
STPSao Tome Island Angolar0.000032See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina Inner Mongolia Region0.0000102See
KORSouth Korea pop 30.0000485See
AUSAustralia Yuendumu Aborigine0.0000191See
USAUSA Alaska Yupik0.0000252See
USAUSA Asian0.0000358See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
HKGHong Kong Chinese0.00.0000569See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore SGVP Chinese CHS0.000096See
MEXMexico Morelos Rural0.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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