Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 39 time(s) and present in 39 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain, Canary Islands, Gran canaria island16.70.0884215See
BRABrazil Barra Mansa Rio State Black0.075373See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)10.00.050010See
CRICosta Rica Central Valley Mestizo (G)9.60.0480221See
BRABrazil Rio de Janeiro Caucasian0.0480521See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
USAUSA Mexican American Mestizo0.0470553See
BRABrazil Barra Mansa Rio State Caucasian0.0469405See
BRABrazil Rio de Janeiro Black0.044868See
USAUSA San Francisco Caucasian0.0440220See
BRABrazil Rio de Janeiro Parda0.0412170See
USAUSA Italy Ancestry0.0400273See
NICNicaragua Mestizo (G)7.80.0390155See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
USAUSA African American pop 30.0270564See
CRICosta Rica Guanacaste Mestizo (G)5.40.0270110See
RUSRussia Belgorod region5.20.0261153See
RUSRussia Bashkortostan, Tatars5.20.0260192See
ENGEngland Blood Donors of Mixed Ethnicity5.00.0260519See
ENGEngland North West5.00.0250298See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
CHLChile Easter Island0.024021See
RUSRussia Nizhny Novgorod, Russians4.60.02321510See
ZAFSouth African Mixed ancestry4.00.020050See
GRCGreece Athens3.80.01911888See
ZAFSouth African Black3.50.0176142See
LBYLibya Cyrenaica0.0170118See
POLPoland BMR2.80.014123595See
MEXMexico Hidalgo Mezquital Valley/ Otomi2.80.013972See
RUSRussia Bashkortostan, Bashkirs2.50.0125120See
CRICosta Rica African -Caribbean (G)2.00.0100102See
SAUSaudi Arabia pop 51.90.0095158See
RUSRussian Federation Vologda Region1.70.0084119See
USAUSA Spain Ancestry0.0040279See
CRICosta Rica Amerindians (G)0.80.0040125See
USAUSA Arizona Gila River Pima0.00163000See
INDIndia Kerala Malayalam speaking0.30.0010356See
CHNChina Zhejiang Han0.00091734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00045266See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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