Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 366 time(s) and present in 338 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Beijing pop 20.4007826See
JPNJapan Hokkaido Ainu0.290050See
SWESweden Northern Sami0.1500154See
MEXMexico Chihuahua Tarahumara0.148044See
SWESweden Southern Sami0.1400130See
MEXMexico Tamaulipas, Ciudad Victoria0.130423See
COLColombia North Wiwa El Encanto0.125052See
CHNChina Tibet Region Tibetan0.1230158See
NLDNetherlands UMCU23.40.117264See
CHNChina Shanxi HIV negative0.114022See
KORSouth Korea pop 30.1050485See
KORSouth Korea pop 80.10207096See
MEXMexico Morelos Rural0.100030See
DEUGermany DKMS - Netherlands minority0.08911374See
JPNJapan Central0.0870371See
KORSouth Korea pop 100.08534128See
USAUSA NMDP Alaska Native or Aleut0.08501376See
USAUSA NMDP Korean0.083977584See
MEXMexico Mexico City North0.0810751See
USAUSA Philadelphia Caucasian14.10.0810141See
DEUGermany pop 60.07978862See
MEXMexico Tlaxcala, Tlaxcala city0.0773181See
NLDNetherlands Leiden0.07701305See
USAUSA NMDP Japanese0.076924582See
JPNJapan pop 160.075918604See
JPNJapan pop 30.07501018See
DEUGermany DKMS - German donors0.07423456066See
MEXMexico Mexico City Metropolitan Area Rural0.0724150See
USAUSA North American Native0.0720187See
USAUSA South Dakota Lakota Sioux0.0710302See
DEUGermany DKMS - Austria minority0.07101698See
CHNChina Beijing Shijiazhuang Tianjian Han0.0700618See
MEXMexico Mexico City East0.068879See
MEXMexico Aguascalientes state0.068495See
USAUSA Caucasian pop 40.06801070See
CHNChina Qinghai Province Hui0.0680110See
CHESwitzerland Aargau-Solothurn0.06781838See
MEXMexico Mexico City South0.067352See
MEXMexico Veracruz, Poza Rica0.066745See
DEUGermany DKMS - United Kingdom minority0.06661043See
MEXMexico Tlaxcala Rural0.0663830See
MEXMexico Sinaloa Rural0.0656183See
MEXMexico Veracruz Xalapa13.10.065584See
JPNJapan pop 50.0650117See
DEUGermany pop 80.064839689See
DEUGermany DKMS - France minority0.06471406See
RUSRussia Karelia0.06411075See
MEXMexico Chichen Itza Maya (prehispanic)0.063847See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
CHESwitzerland Zurich0.06304875See
USAUSA San Francisco Caucasian0.0620220See
USAUSA NMDP North American Amerindian0.061635791See
MEXMexico Coahuila, Saltillo0.061672See
USAUSA NMDP European Caucasian0.06061242890See
CHESwitzerland Bern0.06033545See
USAUSA San Antonio Caucasian0.0602222See
USAUSA Caucasian pop 20.0600265See
TWNTaiwan Rukai12.00.060050See
PRTPortugal Center0.060050See
MEXMexico Mexico City West0.059733See
DEUGermany DKMS - China minority0.05961282See
ENGEngland North West11.70.0590298See
MEXMexico Puebla Rural0.0582833See
USAUSA Alaska Yupik0.0580252See
MEXMexico Puebla, Puebla city0.05741994See
MEXMexico Colima, Colima city0.057461See
MEXMexico Zacatecas, Fresnillo0.0571103See
MEXMexico Yucatan, Merida0.0564192See
AUSAustralia New South Wales Caucasian0.0560134See
MEXMexico Puebla Mestizo0.056099See
USAUSA European American pop 20.05601245See
USAUSA San Diego10.90.0560496See
MEXMexico Hidalgo Rural0.055681See
CZECzech Republic NMDR0.05535099See
FRAFrance Southeast10.80.0550130See
MEXMexico Mexico City Tlalpan10.90.0545330See
CHESwitzerland Basel0.05431888See
USAUSA Caucasian Bethesda10.80.0540307See
FRAFrance French Bone Marrow Donor Registry0.053642623See
MEXMexico Sinaloa, Culiacán0.0534103See
CHNChina Beijing0.053067See
CHESwitzerland Sion0.0530832See
CHESwitzerland St Gallen0.05292113See
POLPoland DKMS0.052020653See
USAUSA NMDP American Indian South or Central America0.05105926See
MEXMexico Chihuahua, Ciudad Juarez0.0509106See
DEUGermany DKMS - Romania minority0.05071234See
MEXMexico San Luis Potosi, San Luis Potosi city0.050030See
MEXMexico Baja California Rural0.050050See
CHNChina Jiangsu Province Han0.0494334See
DEUGermany DKMS - Spain minority0.04891107See
CHNChina Hubei Han9.70.04863732See
CPVCape Verde Northwestern Islands0.048062See
MEXMexico Durango Rural0.0474326See
CHESwitzerland Graubunden0.0473759See
USAUSA Asian0.0470358See
CZECzech Republic0.0470106See
CHNChina Jiangsu Han0.04693238See
MEXMexico Nayarit Rural0.046964See
MEXMexico Veracruz, Veracruz city0.0465171See
IRLIreland South8.80.0460250See
MEXMexico Guanajuato Rural0.0460162See
MEXMexico Veracruz, Xalapa0.0455187See
CHNChina Canton Han0.0450264See
MEXMexico Sinaloa Mestizo0.045056See
MEXMexico Sonora Seri0.045034See
CHNChina Marrow Donor Registry0.0450600See
MEXMexico Guanajuato, Leon0.044978See
MEXMexico Jalisco, Zapopan0.0446168See
MEXMexico Campeche, Campeche city0.044134See
CHNChina Inner Mongolia Region0.0440102See
CHESwitzerland Luzern0.04371553See
MEXMexico Tamaulipas Rural0.0437125See
MEXMexico Coahuila Rural0.0436216See
GTMGuatemala, Guatemala City Mixed Ancestry8.70.0433127See
MEXMexico Oaxaca, Oaxaca city0.0430151See
MEXMexico Jalisco, Tonala0.042935See
CHESwitzerland Geneva pop 20.04281267See
DEUGermany DKMS - Portugal minority0.04251176See
MEXMexico Oaxaca Rural0.0421485See
MEXMexico Sonora, Ciudad Obregón0.0420143See
TWNTaiwan pop 20.0420364See
RUSRussia Tuva pop 20.0420169See
MEXMexico Guerrero state0.0417144See
VNMVietnam Hanoi Kinh pop 20.0410170See
THAThailand Northeast pop 20.0410400See
MEXMexico Nuevo Leon Rural0.0409439See
TWNTaiwan Tzu Chi Morrow Donor Registry0.040646682See
MEXMexico San Luis Potosi Rural0.040287See
MEXMexico Baja California, La Paz0.040075See
MEXMexico Coahuila, Torreon0.0400396See
MEXMexico Quintana Roo Rural0.040050See
CPVCape Verde Southeastern Islands0.040062See
SGPSingapore Chinese8.10.0400149See
MEXMexico Chihuahua Chihuahua City Pop 28.00.039888See
MEXMexico Chihuahua Rural0.0397236See
TWNTaiwan Paiwan7.80.039051See
HRVCroatia pop 40.03894000See
RUSRussia Bering Island Aleuts0.0385104See
CHESwitzerland Lugano0.03831169See
NIRIreland Northern7.40.03801000See
GEOGeorgia Svaneti Region Svan0.038080See
CHNChina North Han0.0380105See
PERPeru Titikaka Lake Uro0.0380105See
TWNTaiwan Tzu Chi Cord Blood Bank0.0380710See
PERPeru Titikaka Lake Uros0.0380105See
MEXMexico Veracruz Rural0.0379539See
MEXMexico Chiapas, Tuxtla Gutierrez0.037752See
MEXMexico Zacatecas Rural0.0372266See
CHNChina Yunnan Hani0.0370150See
MEXMexico Mexico City Mestizo0.0370121See
ITAItaly North Pavia0.037081See
MEXMexico Mestizo7.30.037041See
MEXMexico Tabasco, Villahermosa0.036682See
MEXMexico Hidalgo, Pachuca0.036641See
DEUGermany DKMS - Croatia minority0.03602057See
PRTAzores Central Islands0.036059See
TWNTaiwan pop 30.0360212See
PRTPortugal Azores Terceira Island7.00.0351130See
ITAItaly pop 50.0350975See
MEXMexico Queretaro Rural0.034943See
USAUSA Asian pop 20.03481772See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,6.70.03434335See
MEXMexico Colima Rural0.034143See
TWNTaiwan Minnan pop 15.90.0340102See
MEXMexico Veracruz, Orizaba0.033360See
ISRIsrael USSR Jews0.032845681See
MEXMexico Mexico City Center0.0325152See
MEXMexico Durango, Durango city0.0323153See
MEXMexico Jalisco, Guadalajara city0.03221189See
MEXMexico Quintana Roo, Cancun0.031348See
PRTAzores Terceira Island0.0310130See
CHLChile Mapuche0.030866See
USAUSA NMDP Mexican or Chicano0.0306261235See
MEXMexico Morelos, Cuernavaca0.030582See
MEXMexico Sonora, Hermosillo0.030399See
MEXMexico Baja Californa, Mexicali0.0300100See
CHNChina Yunnan Province Han0.0300101See
USAUSA NMDP Chinese0.030099672See
MEXMexico Tixcacaltuyub Maya0.029967See
MEXMexico Michoacan, Morelia0.0298150See
DEUGermany DKMS - Italy minority0.02981159See
CHNChina Sichuan HIV negative0.029034See
TWNTaiwan Siraya5.90.029051See
USAUSA Hispanic pop 20.02881999See
HKGHong Kong Chinese BMDR0.02867595See
MEXMexico Jalisco Rural0.0282585See
MEXMexico Tabasco Rural0.0282142See
USAUSA Hispanic0.0280234See
HKGHong Kong Chinese cord blood registry0.02773892See
USAUSA NMDP Hispanic South or Central American0.0271146714See
NICNicaragua Managua5.40.0271339See
TWNTaiwan Pazeh5.50.027055See
TWNTaiwan Hakka5.50.027055See
SGPSingapore SGVP Chinese CHS0.027096See
TWNTaiwan Han Chinese0.0260504See
CHNChina Yunnan Province Nu0.0260107See
CHNChina Uyghur HIV negative0.026019See
MEXMexico Jalisco, Tlaquepaque0.025639See
UGAUganda Kampala0.0250161See
SGPSingapore SGVP. Indian INS0.025086See
CUBCuba Mixed Race4.80.024042See
SRBSerbia pop 24.90.0240102See
USAUSA NMDP Caribean Hispanic0.0234115374See
USAUSA NMDP Middle Eastern or North Coast of Africa0.023370890See
MYSMalaysia Peninsular Chinese4.10.0232194See
ECUEcuador Andes Mixed Ancestry0.0231824See
ECUEcuador Mixed Ancestry0.02301173See
LKASri Lanka Colombo4.30.0230714See
ZMBZambia Lusaka0.023044See
ARGArgentina Rosario Toba4.70.023086See
MEXMexico Michoacan Rural0.0229348See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02291028See
MEXMexico Yucatan Rural0.0224132See
DEUGermany DKMS - Greece minority0.02231894See
CHNChina Yunnan Bulang0.0220116See
HKGHong Kong Chinese4.20.0220569See
MEXMexico Mexico City Mestizo pop 20.0214234See
CHESwitzerland Lausanne0.0213993See
MEXMexico Campeche Rural0.021347See
COLColombia North Chimila Amerindians0.021247See
USAUSA NMDP Caribean Indian0.021014339See
CUBCuba Caucasian4.30.021070See
DEUGermany DKMS - Turkey minority0.02074856See
MEXMexico Nayarit, Tepic0.020697See
IRNIran Tabriz Azeris0.020697See
INDIndia Northeast UCBB4.10.0203296See
USAUSA NMDP Hawaiian or other Pacific Islander0.020111499See
PRTPortugal South0.020049See
MEXMexico Baja California, Tijuana0.020025See
INDIndia Kerala Malayalam speaking3.90.0200356See
INDIndia North pop 20.019072See
NCLNew Caledonia0.019065See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
NZLNew Zealand Maori with Admixed History3.80.0190105See
INDIndia Central UCBB3.80.01894204See
INDIndia Tamil Nadu0.01872492See
SDNSudan East Rashaida3.70.018627See
COLColombia Bogotá Cord Blood3.60.01811463See
ITAItaly South Campania Region3.60.01811089See
MEXMexico Veracruz, Cordoba0.017956See
MEXMexico Zacatecas, Zacatecas city0.017984See
MEXMexico Nuevo Leon, Monterrey city0.0177226See
MEXMexico Mexico City Mestizo population0.0175143See
ISRIsrael YemenJews0.017415542See
USAUSA South Texas Hispanic0.0170194See
TWNTaiwan Thao3.30.017030See
BRABrazil Puyanawa3.30.0170150See
ECUEcuador Coast Mixed Ancestry0.0168238See
MEXMexico Chihuahua Chihuahua City0.0168119See
INDIndia North UCBB3.30.01665849See
MEXMexico Chiapas Rural0.0165121See
USAUSA NMDP South Asian Indian0.0161185391See
USAUSA NMDP Southeast Asian0.016127978See
ZAFSouth Africa Worcester3.00.0160159See
USAUSA African American Bethesda3.20.0160187See
INDIndia Delhi pop 23.30.016090See
STPSao Tome Island Angolar0.016032See
MEXMexico Sonora Rural0.0152197See
INDIndia West UCBB3.00.01525829See
STPSao Tome Island Forro0.015066See
CHNChina Guizhou Province Shui0.0150153See
CHNChina Guangzhou0.0150102See
ARMArmenia combined Regions0.0150100See
INDIndia East UCBB3.00.01482403See
CHNChina Guangxi Region Maonan0.0140108See
CHNChina Yunnan Province Lisu0.0140111See
USAUSA NMDP Filipino0.013250614See
PRTAzores Oriental Islands0.013043See
PNGPapua New Guinea East New Britain Rabaul0.013060See
MYSMalaysia Peninsular Indian2.60.0129271See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0129233See
ECUEcuador Amazonia Mixed Ancestry0.012839See
GRCGreece pop 82.40.012183See
SGPSingapore SGVP Malay MAS0.012089See
MEXMexico Queretaro, Queretaro city0.011145See
ISRIsrael Ethiopia Jews0.01115928See
PRTPortugal North0.011046See
BRABrazil Belo Horizonte Caucasian2.10.011095See
CMRCameroon Yaounde0.011092See
AREUnited Arab Emirates pop 22.10.0110373See
USAUSA NMDP African American pop 20.0108416581See
USAUSA NMDP Vietnamese0.010843540See
INDIndia South UCBB2.00.010211446See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
MEXMexico Mixtec0.010097See
CHNChina Guizhou Province Bouyei0.0100109See
THAThailand pop 30.010049See
USAUSA African American pop 80.0100605See
CHLChile Santiago Mixed2.00.010070See
USAUSA African American0.0100252See
ISRIsrael Iraq Jews0.009913270See
ISRIsrael Morocco Jews0.009836718See
USAUSA African American pop 40.00982411See
ISRIsrael Ashkenazi Jews pop 30.00964625See
AREUnited Arab Emirates Abu Dhabi0.009652See
GRCGreece pop 60.0094242See
USAUSA NMDP Caribean Black0.009033328See
USAUSA Arizona Gila River Amerindian0.0090492See
IRNIran Yazd0.008956See
MEXMexico Veracruz, Coatzacoalcos0.008955See
ISRIsrael Georgia Jews0.00864471See
CHNChina Southwest Dai0.0080124See
PNGPapua New Guinea Wanigela Keapara0.008066See
AUSAustralia Yuendumu Aborigine0.0080191See
MEXMexico Oaxaca Zapotec0.007090See
USAUSA NMDP African0.006628557See
ISRIsrael Kavkazi Jews0.00632840See
CHNChina Guizhou Province Miao pop 20.006085See
ESPSpain Andalusia0.006099See
ESPSpain Andalusia Romani0.005099See
SDNSudan Mixed1.00.0050200See
ZAFSouth Africa Natal Zulu1.00.0050100See
TWNTaiwan Bunun1.00.0050101See
ISRIsrael Tunisia Jews0.00479070See
ARGArgentina Gran Chaco Eastern Toba0.90.0040135See
AREUnited Arab Emirates Pop 10.0040570See
ISRIsrael Poland Jews0.004013871See
MYSMalaysia Peninsular Malay0.70.0037951See
ISRIsrael Libya Jews0.00343739See
ISRIsrael Arab pop 20.003212301See
ISRIsrael USA Jews0.00316058See
ISRIsrael Iran Jews0.00288153See
ISRIsrael Druze0.00255914See
ISRIsrael Argentina Jews0.00244307See
MEXMexico Chiapas Lacandon Mayans0.0023218See
ISRIsrael Bukhara Jews0.00112317See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Jalisco, Tlajomulco0.000030See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
ARGArgentina Gran Chaco Mataco Wichi0.00.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.00.000019See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
MARMorocco Nador Metalsa pop 20.000073See
TWNTaiwan Tsou0.00.000051See
PHLPhilippines Ivatan0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
MEXMexico Oaxaca Mixtec0.0000103See
INDIndia Mumbai Maratha0.000091See
MARMorocco Settat Chaouya0.00.000098See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Rimaibe0.000047See
GNBGuinea Bissau0.000065See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional