Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 202 time(s) and present in 99 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
CHNChina Beijing pop 20.0257826See
ZAFSouth Africa Natal Tamil0.020051See
MEXMexico Oaxaca, Oaxaca city0.0199151See
MEXMexico Chiapas, Tuxtla Gutierrez0.018952See
MEXMexico Colima, Colima city0.016461See
LKASri Lanka Colombo3.20.0160714See
INDIndia Delhi pop 23.30.016090See
MEXMexico Jalisco, Tonala0.014335See
INDIndia Andhra Pradesh Golla0.0140111See
MEXMexico Guanajuato Rural0.0123162See
MEXMexico Tlaxcala, Tlaxcala city0.0111181See
INDIndia North pop 20.010072See
CHNChina Inner Mongolia Region0.0100102See
BRABrazil Terena1.70.009060See
MEXMexico Jalisco, Zapopan0.0089168See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Veracruz, Coatzacoalcos0.008955See
PNGPapua New Guinea Wanigela Keapara0.008066See
MYSMalaysia Peninsular Indian1.50.0074271See
MEXMexico Coahuila Rural0.0069216See
MEXMexico Coahuila, Saltillo0.006872See
MEXMexico Mexico City Metropolitan Area Rural0.0066150See
ECUEcuador Coast Mixed Ancestry0.0063238See
MEXMexico Mexico City Tlalpan1.20.0061330See
SGPSingapore SGVP. Indian INS0.006086See
MEXMexico Jalisco, Guadalajara city0.00591189See
MEXMexico Veracruz, Veracruz city0.0058171See
INDIndia South UCBB1.20.005811446See
INDIndia West UCBB1.10.00555829See
MEXMexico Aguascalientes state0.005395See
INDIndia Tamil Nadu0.00512492See
CHNChina Qinghai Province Hui0.0050110See
CHNChina Guangxi Region Maonan0.0050108See
CHNChina Guangdong Province Meizhou Han0.0050100See
MEXMexico Sinaloa, Culiacán0.0049103See
MEXMexico Puebla Rural0.0048833See
INDIndia East UCBB0.90.00462403See
MEXMexico Nuevo Leon Rural0.0045439See
USAUSA NMDP South Asian Indian0.0045185391See
MEXMexico Nuevo Leon, Monterrey city0.0044226See
MEXMexico Michoacan Rural0.0043348See
MEXMexico Coahuila, Torreon0.0038396See
INDIndia North UCBB0.80.00385849See
INDIndia Central UCBB0.70.00374204See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Guerrero state0.0035144See
MEXMexico Jalisco Rural0.0034585See
INDIndia Northeast UCBB0.70.0034296See
MEXMexico Mexico City North0.0033751See
USAUSA NMDP Southeast Asian0.003327978See
MEXMexico Mexico City Center0.0032152See
MEXMexico Durango Rural0.0031326See
MEXMexico Puebla, Puebla city0.00301994See
MEXMexico Tlaxcala Rural0.0030830See
CHNChina Marrow Donor Registry0.0030600See
ZAFSouth Africa Worcester1.00.0030159See
ECUEcuador Mixed Ancestry0.00301173See
USAUSA Asian pop 20.00281772See
MEXMexico Yucatan, Merida0.0026192See
MYSMalaysia Peninsular Chinese0.50.0026194See
ECUEcuador Andes Mixed Ancestry0.0024824See
MEXMexico Oaxaca Rural0.0021485See
COLColombia Bogotá Cord Blood0.40.00211463See
CHNChina Canton Han0.0020264See
CHNChina South Han0.0020284See
AREUnited Arab Emirates Pop 10.0020570See
USAUSA Caucasian pop 20.0020265See
TWNTaiwan pop 30.0020212See
USAUSA Hispanic0.0020234See
MEXMexico Zacatecas Rural0.0019266See
CHNChina Hubei Han0.30.00163732See
DEUGermany DKMS - China minority0.00121282See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
JPNJapan pop 30.00101018See
USAUSA NMDP Caribean Indian0.001014339See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
CHNChina Jiangsu Han0.00083238See
USAUSA NMDP Hawaiian or other Pacific Islander0.000511499See
HKGHong Kong Chinese cord blood registry0.00053892See
MYSMalaysia Peninsular Malay0.10.0005951See
USAUSA NMDP Chinese0.000499672See
USAUSA NMDP Hispanic South or Central American0.0004146714See
SAUSaudi Arabia pop 6 (G)0.000328927See
HKGHong Kong Chinese BMDR0.00037595See
USAUSA NMDP Caribean Black0.000233328See
USAUSA NMDP Vietnamese0.000143540See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
USAUSA NMDP North American Amerindian0.000135791See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP Korean0.000077584See
USAUSA NMDP African American pop 20.0000416581See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA North American Native0.0000187See
USAUSA Asian0.0000358See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA African American0.0000252See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Hispanic pop 20.00001999See
ECUEcuador Amazonia Mixed Ancestry0.000039See
DEUGermany pop 80.000039689See
HKGHong Kong Chinese0.00.0000569See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
KORSouth Korea pop 30.0000485See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Baja California, Tijuana0.000025See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Colima Rural0.000043See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Morelos Rural0.000030See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Veracruz Rural0.0000539See
MEXMexico Hidalgo Rural0.000081See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
MEXMexico Mexico City East0.000079See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Mexico City South0.000052See
MEXMexico Veracruz, Orizaba0.000060See
NCLNew Caledonia0.000065See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
MEXMexico Nayarit Rural0.000064See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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