Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 217 time(s) and present in 98 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BFABurkina Faso Fulani0.041049See
ESPSpain Andalusia Romani0.030099See
INDIndia West Coast Parsi0.030050See
MEXMexico Mestizo4.90.024041See
SDNSudan East Rashaida3.70.018627See
MEXMexico Mexico City East0.012579See
CHESwitzerland Graubunden0.0118759See
ITAItaly South Campania Region2.30.01151089See
BFABurkina Faso Rimaibe0.011047See
MEXMexico Sonora, Hermosillo0.010199See
CHNChina Inner Mongolia Region0.0100102See
MEXMexico Mexico City Center0.0097152See
MEXMexico Zacatecas, Fresnillo0.0095103See
MEXMexico Guanajuato Rural0.0092162See
MLIMali Bandiagara0.0070138See
MEXMexico Guerrero state0.0069144See
MEXMexico Tabasco, Villahermosa0.006182See
ITAItaly pop 50.0060975See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MEXMexico Michoacan Rural0.0057348See
MEXMexico Coahuila, Torreon0.0050396See
CZECzech Republic0.0050106See
MEXMexico Guadalajara Mestizo pop 20.0050103See
MEXMexico Durango Rural0.0046326See
ECUEcuador Coast Mixed Ancestry0.0042238See
MEXMexico Tamaulipas Rural0.0040125See
USAUSA Philadelphia Caucasian0.70.0040141See
MEXMexico Zacatecas Rural0.0037266See
MEXMexico Mexico City Mestizo population0.0035143See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Durango, Durango city0.0032153See
USAUSA Mexican American Mestizo0.0030553See
RUSRussia Bashkortostan, Tatars0.50.0026192See
DEUGermany DKMS - Italy minority0.00261159See
MEXMexico Oaxaca Rural0.0021485See
KENKenya Nandi0.0020240See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
USAUSA San Diego0.30.0020496See
USAUSA San Francisco Caucasian0.0020220See
NICNicaragua Managua0.30.0015339See
COLColombia Bogotá Cord Blood0.30.00141463See
MEXMexico Jalisco, Guadalajara city0.00131189See
USAUSA NMDP Middle Eastern or North Coast of Africa0.001170890See
THAThailand Northeast pop 20.0010400See
USAUSA African American pop 80.0010605See
MEXMexico Puebla, Puebla city0.00101994See
AREUnited Arab Emirates Pop 10.0010570See
CZECzech Republic NMDR0.00095099See
DEUGermany DKMS - Spain minority0.00091107See
MEXMexico Veracruz Rural0.0009539See
MEXMexico Jalisco Rural0.0009585See
ECUEcuador Mixed Ancestry0.00091173See
USAUSA NMDP Caribean Hispanic0.0008115374See
DEUGermany DKMS - France minority0.00071406See
DEUGermany DKMS - Netherlands minority0.00071374See
USAUSA NMDP Hispanic South or Central American0.0007146714See
ISRIsrael Iraq Jews0.000613270See
DEUGermany DKMS - Austria minority0.00061698See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00064335See
DEUGermany DKMS - Turkey minority0.00064856See
DEUGermany pop 80.000639689See
MEXMexico Tlaxcala Rural0.0006830See
MEXMexico Puebla Rural0.0006833See
USAUSA NMDP Mexican or Chicano0.0006261235See
USAUSA Hispanic pop 20.00051999See
DEUGermany DKMS - Romania minority0.00041234See
DEUGermany DKMS - German donors0.00043456066See
ISRIsrael Kavkazi Jews0.00042840See
INDIndia North UCBB0.10.00035849See
ISRIsrael YemenJews0.000315542See
ISRIsrael Morocco Jews0.000336718See
DEUGermany pop 60.00038862See
USAUSA NMDP Southeast Asian0.000327978See
ISRIsrael Argentina Jews0.00024307See
USAUSA NMDP European Caucasian0.00021242890See
INDIndia Tamil Nadu0.00022492See
HRVCroatia pop 40.00024000See
DEUGermany DKMS - Greece minority0.00031894See
SAUSaudi Arabia pop 6 (G)0.000228927See
USAUSA NMDP South Asian Indian0.0002185391See
ISRIsrael Arab pop 20.000212301See
USAUSA NMDP North American Amerindian0.000135791See
INDIndia Central UCBB0.00.00014204See
ISRIsrael Georgia Jews0.00014471See
USAUSA NMDP African0.000128557See
POLPoland BMR0.00.000123595See
POLPoland DKMS0.000220653See
CHNChina Hubei Han0.00.00013732See
INDIndia West UCBB0.00.00015829See
ISRIsrael USA Jews0.00016058See
USAUSA NMDP Caribean Black0.000133328See
ISRIsrael USSR Jews0.000145681See
USAUSA NMDP African American pop 20.0001416581See
INDIndia South UCBB0.00.000011446See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Chinese0.000099672See
SGPSingapore Chinese0.00.0000149See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See
USAUSA European American pop 20.00001245See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PHLPhilippines Ivatan0.00.000050See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Zacatecas, Zacatecas city0.000084See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
UGAUganda Kampala0.0000161See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
HKGHong Kong Chinese0.00.0000569See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
CHNChina Qinghai Province Hui0.0000110See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico San Luis Potosi Rural0.000087See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Morelos Rural0.000030See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Nayarit Rural0.000064See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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