Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 238 time(s) and present in 133 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CIVIvory Coast Adiopodoume Akan0.046044See
MEXMexico Chiapas, Tuxtla Gutierrez0.037752See
CMRCameroon Bamileke0.032077See
MEXMexico Sinaloa Mestizo0.027056See
GHAGhana Ga-Adangbe5.30.0267131See
GHAGhana Accre Asutuare Akan0.0210429See
USAUSA NMDP Caribean Black0.020533328See
USAUSA African American pop 80.0200605See
MEXMexico Mexico City South0.019252See
USAUSA African American pop 30.0190564See
USAUSA NMDP African American pop 20.0180416581See
USAUSA NMDP African0.017928557See
USAUSA African American pop 40.01662411See
ITAItaly South Campania Region3.20.01611089See
USAUSA African American Bethesda3.20.0160187See
USAUSA NMDP Caribean Indian0.015014339See
AREUnited Arab Emirates pop 22.90.0150373See
MEXMexico Jalisco, Tonala0.014335See
BRABrazil Mixed0.0140108See
PRTAzores Oriental Islands0.013043See
ZWEZimbabwe Harare Shona0.0130230See
MEXMexico Jalisco, Tlaquepaque0.012839See
MEXMexico Sonora Rural0.0127197See
MLIMali Bandiagara0.0110138See
TUNTunisia pop 30.0110104See
CMRCameroon Beti0.0110174See
CMRCameroon Yaounde0.011092See
USAUSA NMDP Caribean Hispanic0.0108115374See
MEXMexico Sonora, Hermosillo0.010199See
KENKenya Nandi0.0100240See
USAUSA African American0.0100252See
AREUnited Arab Emirates Abu Dhabi0.009652See
MEXMexico Chihuahua, Ciudad Juarez0.0093106See
MEXMexico Guanajuato Rural0.0092162See
MEXMexico Colima, Colima city0.008261See
CPVCape Verde Southeastern Islands0.008062See
MEXMexico Tamaulipas Rural0.0079125See
MEXMexico Mexico City Mestizo population0.0070143See
MEXMexico Oaxaca, Oaxaca city0.0066151See
MEXMexico Mexico City Center0.0065152See
MEXMexico Guanajuato, Leon0.006478See
MEXMexico Morelos, Cuernavaca0.006182See
NICNicaragua Managua1.20.0060339See
UGAUganda Kampala0.0060161See
TUNTunisia Gabes0.005295See
SDNSudan Mixed0.50.0050200See
USAUSA San Diego1.00.0050496See
ZAFSouth Africa Natal Zulu1.00.0050100See
ZAFSouth Africa Caucasians0.0050102See
MEXMexico Baja Californa, Mexicali0.0050100See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
MEXMexico Puebla Mestizo0.005099See
BRABrazil Belo Horizonte Caucasian1.10.005095See
CHESwitzerland Luzern0.00491553See
MEXMexico Sinaloa, Culiacán0.0049103See
MEXMexico Zacatecas, Fresnillo0.0048103See
MEXMexico Durango Rural0.0046326See
MEXMexico Coahuila Rural0.0046216See
USAUSA Hispanic pop 20.00451999See
MEXMexico Chihuahua Chihuahua City0.0042119See
MEXMexico Mexico City Mestizo0.0040121See
KENKenya Luo0.0040265See
USAUSA Spain Ancestry0.0040279See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Sonora, Ciudad Obregón0.0035143See
USAUSA NMDP Hispanic South or Central American0.0031146714See
USAUSA Mexican American Mestizo0.0030553See
USAUSA North American Native0.0030187See
UGAUganda Kampala pop 20.0030175See
ZAFSouth Africa Worcester1.00.0030159See
MEXMexico Michoacan Rural0.0029348See
DEUGermany DKMS - Portugal minority0.00301176See
ISRIsrael Arab pop 20.002612301See
GRCGreece pop 60.0024242See
MEXMexico Nuevo Leon, Monterrey city0.0022226See
MEXMexico Mexico City Mestizo pop 20.0021234See
ENGEngland North West0.30.0020298See
ITAItaly pop 50.0020975See
AREUnited Arab Emirates Pop 10.0020570See
USAUSA European American pop 20.00201245See
USAUSA Italy Ancestry0.0020273See
USAUSA Hispanic0.0020234See
USAUSA NMDP Mexican or Chicano0.0019261235See
USAUSA Caucasian pop 40.00191070See
MEXMexico Zacatecas Rural0.0019266See
CHESwitzerland Lausanne0.0017993See
ISRIsrael Poland Jews0.001513871See
MEXMexico Mexico City North0.0013751See
MEXMexico Jalisco, Guadalajara city0.00131189See
COLColombia Bogotá Cord Blood0.20.00101463See
USAUSA Asian0.0010358See
USAUSA NMDP American Indian South or Central America0.00105926See
SAUSaudi Arabia pop 6 (G)0.001028927See
ISRIsrael Argentina Jews0.00094307See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.20.00094335See
DEUGermany DKMS - United Kingdom minority0.00101043See
MEXMexico Veracruz Rural0.0009539See
USAUSA NMDP North American Amerindian0.000935791See
ISRIsrael USSR Jews0.000845681See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000770890See
ISRIsrael USA Jews0.00076058See
ISRIsrael Ashkenazi Jews pop 30.00064625See
ECUEcuador Andes Mixed Ancestry0.0006824See
USAUSA NMDP European Caucasian0.00061242890See
USAUSA NMDP Hawaiian or other Pacific Islander0.000511499See
MEXMexico Puebla, Puebla city0.00051994See
ECUEcuador Mixed Ancestry0.00041173See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - Italy minority0.00041159See
CHESwitzerland Bern0.00043545See
ISRIsrael YemenJews0.000215542See
DEUGermany DKMS - German donors0.00023456066See
DEUGermany pop 80.000239689See
CZECzech Republic NMDR0.00025099See
DEUGermany pop 60.00018862See
POLPoland DKMS0.000120653See
ISRIsrael Ethiopia Jews0.00015928See
ISRIsrael Iraq Jews0.000113270See
ISRIsrael Morocco Jews0.000136718See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Tunisia Jews0.00019070See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Filipino0.000050614See
USAUSA NMDP Southeast Asian0.000027978See
USAUSA NMDP Chinese0.000099672See
SGPSingapore Chinese0.00.0000149See
USAUSA Asian pop 20.00001772See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian Bethesda0.00.0000307See
PHLPhilippines Ivatan0.00.000050See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PRTAzores Central Islands0.000059See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
ZMBZambia Lusaka0.000044See
HKGHong Kong Chinese0.00.0000569See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
GNBGuinea Bissau0.000065See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
CPVCape Verde Northwestern Islands0.000062See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
BFABurkina Faso Fulani0.000049See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina North Han0.0000105See
CHNChina Tibet Region Tibetan0.0000158See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Guerrero state0.0000144See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Aguascalientes state0.000095See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Mexico City East0.000079See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Nayarit Rural0.000064See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Colima Rural0.000043See
MEXMexico Baja California Rural0.000050See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Puebla Rural0.0000833See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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