Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 291 time(s) and present in 171 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Beijing pop 20.0919826See
ZAFSouth Africa Natal Tamil0.041051See
CHNChina Tibet Region Tibetan0.0380158See
INDIndia Mumbai Maratha0.037091See
CHNChina North Han0.0290105See
USAUSA Hawaii Okinawa0.0290106See
CHNChina Guangzhou Han0.0240106See
INDIndia Andhra Pradesh Golla0.0240111See
CHNChina Beijing0.023067See
LKASri Lanka Colombo4.30.0220714See
INDIndia Tamil Nadu0.02092492See
INDIndia South UCBB4.10.020511446See
MYSMalaysia Patani4.00.020025See
CHNChina Jiangsu Province Han0.0193334See
TWNTaiwan Hakka3.60.018055See
JPNJapan pop 30.01701018See
JPNJapan pop 50.0170117See
MYSMalaysia Peninsular Indian3.30.0166271See
INDIndia Delhi pop 23.30.016090See
USAUSA NMDP Japanese0.015424582See
JPNJapan pop 160.015218604See
JPNJapan Central0.0150371See
CHNChina Sichuan HIV negative0.015034See
CHNChina Inner Mongolia Region0.0150102See
DEUGermany DKMS - China minority0.01481282See
CZECzech Republic0.0140106See
CHNChina Qinghai Province Hui0.0140110See
USAUSA Asian0.0140358See
USAUSA NMDP South Asian Indian0.0135185391See
USAUSA NMDP Korean0.013577584See
INDIndia Central UCBB2.60.01324204See
KORSouth Korea pop 100.01314128See
KORSouth Korea pop 80.01307096See
CHNChina Yunnan Province Nu0.0130107See
CHNChina Jiangsu Han0.01303238See
INDIndia West UCBB2.50.01265829See
CHNChina Marrow Donor Registry0.0120600See
INDIndia North UCBB2.40.01205849See
INDIndia East UCBB2.30.01172403See
SENSenegal Niokholo Mandenka0.0110165See
ZMBZambia Lusaka0.011044See
CHNChina Beijing Shijiazhuang Tianjian Han0.0110618See
CIVIvory Coast Adiopodoume Akan0.011044See
USAUSA NMDP Southeast Asian0.010027978See
TWNTaiwan Han Chinese0.0100504See
SGPSingapore Javaneses0.010051See
THAThailand pop 30.010049See
PRTPortugal Center0.010050See
USAUSA Asian pop 20.00991772See
USAUSA NMDP Chinese0.009399672See
USAUSA NMDP Caribean Indian0.009014339See
KORSouth Korea pop 30.0090485See
INDIndia Northeast UCBB1.70.0085296See
CHNChina Hubei Han1.60.00823732See
CPVCape Verde Northwestern Islands0.008062See
CPVCape Verde Southeastern Islands0.008062See
FRAFrance Southeast1.50.0080130See
GNBGuinea Bissau0.008065See
USAUSA African American0.0080252See
STPSao Tome Island Forro0.008066See
USAUSA NMDP Caribean Hispanic0.0072115374See
GRCGreece pop 60.0071242See
CHNChina South Han0.0070284See
CHNChina Yunnan Province Lisu0.0070111See
ITAItaly pop 50.0070975See
USAUSA NMDP Vietnamese0.006343540See
USAUSA Eastern European0.0060558See
USAUSA San Antonio Caucasian0.0060222See
SGPSingapore Chinese Han0.006094See
RUSRussia Tuva pop 20.0060169See
CHNChina Canton Han0.0060264See
AREUnited Arab Emirates Pop 10.0060570See
ESPSpain Andalusia0.006099See
TWNTaiwan Tzu Chi Morrow Donor Registry0.005846682See
CHESwitzerland Zurich0.00574875See
MYSMalaysia Peninsular Chinese1.00.0052194See
TWNTaiwan Minnan pop 11.00.0050102See
TWNTaiwan Tzu Chi Cord Blood Bank0.0050710See
CHNChina Guangzhou0.0050102See
HKGHong Kong Chinese cord blood registry0.00493892See
CHESwitzerland St Gallen0.00482113See
CHESwitzerland Basel0.00461888See
PRTPortugal Azores Terceira Island0.90.0044130See
CHESwitzerland Bern0.00433545See
DEUGermany DKMS - Portugal minority0.00431176See
MEXMexico Chiapas Rural0.0041121See
HKGHong Kong Chinese BMDR0.00417595See
IRLIreland South0.80.0040250See
PRTAzores Terceira Island0.0040130See
MLIMali Bandiagara0.0040138See
USAUSA Caucasian pop 20.0040265See
USAUSA Caucasian Bethesda0.80.0040307See
USAUSA Philadelphia Caucasian0.70.0040141See
HKGHong Kong Chinese0.70.0040569See
AUSAustralia New South Wales Caucasian0.0040134See
CHNChina Southwest Dai0.0040124See
DEUGermany DKMS - France minority0.00391406See
CHESwitzerland Lugano0.00381169See
USAUSA Caucasian pop 40.00371070See
MYSMalaysia Peninsular Malay0.60.0032951See
CHESwitzerland Luzern0.00321553See
DEUGermany DKMS - Turkey minority0.00314856See
ENGEngland North West0.70.0030298See
SDNSudan Mixed0.50.0030200See
USAUSA NMDP American Indian South or Central America0.00305926See
VNMVietnam Hanoi Kinh pop 20.0030170See
USAUSA Hispanic pop 20.00301999See
USAUSA African American pop 80.0030605See
USAUSA NMDP Middle Eastern or North Coast of Africa0.003070890See
DEUGermany DKMS - Greece minority0.00261894See
USAUSA NMDP European Caucasian0.00261242890See
USAUSA NMDP North American Amerindian0.002535791See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.50.00254335See
CHESwitzerland Geneva pop 20.00251267See
DEUGermany DKMS - Austria minority0.00241698See
USAUSA NMDP Hispanic South or Central American0.0021146714See
MEXMexico Mexico City Mestizo pop 20.0021234See
NIRIreland Northern0.40.00201000See
KENKenya Luo0.0020265See
USAUSA San Diego0.30.0020496See
TWNTaiwan pop 20.0020364See
TWNTaiwan pop 30.0020212See
USAUSA Mexican American Mestizo0.0020553See
USAUSA San Francisco Caucasian0.0020220See
USAUSA Spain Ancestry0.0020279See
USAUSA European American pop 20.00201245See
ZWEZimbabwe Harare Shona0.0020230See
USAUSA NMDP Filipino0.001950614See
CZECzech Republic NMDR0.00195099See
DEUGermany pop 80.001939689See
DEUGermany DKMS - United Kingdom minority0.00191043See
HRVCroatia pop 40.00194000See
DEUGermany DKMS - Croatia minority0.00192057See
USAUSA NMDP Hawaiian or other Pacific Islander0.001811499See
DEUGermany DKMS - Netherlands minority0.00181374See
DEUGermany DKMS - Spain minority0.00181107See
DEUGermany pop 60.00198862See
DEUGermany DKMS - German donors0.00183456066See
DEUGermany DKMS - Romania minority0.00161234See
CHESwitzerland Sion0.0016832See
USAUSA NMDP African American pop 20.0015416581See
CHESwitzerland Lausanne0.0015993See
USAUSA NMDP Caribean Black0.001533328See
USAUSA NMDP Mexican or Chicano0.0014261235See
ISRIsrael Arab pop 20.001312301See
USAUSA NMDP African0.001228557See
DEUGermany DKMS - Italy minority0.00131159See
POLPoland DKMS0.001220653See
ISRIsrael Bukhara Jews0.00112317See
COLColombia Bogotá Cord Blood0.20.00101463See
NLDNetherlands Leiden0.00101305See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA African American pop 30.0010564See
USAUSA African American pop 40.00102411See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00101028See
RUSRussia Karelia0.00051075See
ISRIsrael Poland Jews0.000413871See
ISRIsrael Kavkazi Jews0.00042840See
ISRIsrael Iraq Jews0.000313270See
ISRIsrael Ethiopia Jews0.00035928See
ISRIsrael Ashkenazi Jews pop 30.00034625See
ISRIsrael USSR Jews0.000345681See
ISRIsrael USA Jews0.00026058See
ISRIsrael Druze0.00015914See
ISRIsrael Morocco Jews0.000136718See
ISRIsrael Libya Jews0.00013739See
ISRIsrael Tunisia Jews0.00019070See
JPNJapan Hokkaido Ainu0.000050See
KENKenya Nandi0.0000240See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
SGPSingapore Chinese0.00.0000149See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
PHLPhilippines Ivatan0.00.000050See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
USAUSA North American Native0.0000187See
USAUSA African American Bethesda0.00.0000187See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA Hispanic0.0000234See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
UGAUganda Kampala0.0000161See
STPSao Tome Island Angolar0.000032See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Graubunden0.0000759See
AUSAustralia Yuendumu Aborigine0.0000191See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Veracruz Rural0.0000539See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Puebla Rural0.0000833See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Guadalajara city0.00001189See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Puebla, Puebla city0.00001994See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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