Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 59 time(s) and present in 58 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia Arhuaco NA-DHS_16 (G)35.30.176517See
COLColombia Wayuu NA-DHS_15 (G)33.30.166715See
RUSRussia Belgorod region22.90.1275153See
GRCGreece Athens19.40.09691888See
POLPoland BMR14.00.072723595See
ZAFSouth African Mixed ancestry14.00.070050See
IDNIndonesia Sundanese and Javanese0.0700201See
RUSRussia Nizhny Novgorod, Russians13.20.06821510See
ESPSpain, Canary Islands, Gran canaria island12.10.0628215See
RUSRussian Federation Vologda Region11.80.0588119See
USAUSA Eastern European0.0550558See
MEXMexico Guadalajara Mestizo pop 20.0530103See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
MARMorocco Nador Metalsa pop 20.051073See
ZAFSouth Africa Caucasians0.0510102See
USAUSA Italy Ancestry0.0510273See
COLColombia Waunana NA-DHS_20 (G)5.00.050020See
BRABrazil Barra Mansa Rio State Caucasian0.0469405See
USAUSA Mexican American Mestizo0.0460553See
CRICosta Rica Guanacaste Mestizo (G)9.20.0460110See
CRICosta Rica Central Valley Mestizo (G)9.00.0450221See
RUSRussia Bashkortostan, Tatars8.90.0443192See
USAUSA San Francisco Caucasian0.0410220See
CPVCape Verde Northwestern Islands0.040062See
USAUSA Spain Ancestry0.0390279See
GNBGuinea Bissau0.038065See
COLColombia Kogi NA-DHS_17 (G)7.10.035715See
BRABrazil Rio de Janeiro Caucasian0.0336521See
CANCanada Ojibwa NA-DHS_4 (G)6.70.033316See
RUSRussia Bashkortostan, Bashkirs6.70.0333120See
USAUSA African American pop 30.0330564See
BRABrazil Rio de Janeiro Parda0.0324170See
CPVCape Verde Southeastern Islands0.032062See
ZAFSouth African Black6.30.0317142See
COLColombia Zenu NA-DHS_18 (G)6.30.031316See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.30.031316See
CHNChina Jingpo Minority5.80.0290105See
INDIndia Karnataka Kannada Speaking5.70.0290174See
IDNIndonesia Java pop 20.028036See
BRABrazil Barra Mansa Rio State Black0.027473See
SAUSaudi Arabia pop 6 (G)0.027428927See
ENGEngland Blood Donors of Mixed Ethnicity5.40.0270519See
CRICosta Rica African -Caribbean (G)5.00.0250102See
INDIndia Andhra Pradesh Telugu Speaking4.80.0242186See
NICNicaragua Mestizo (G)4.60.0230155See
LBYLibya Cyrenaica0.0210118See
INDIndia Kerala Malayalam speaking2.80.0150356See
BRABrazil Rio de Janeiro Black0.014968See
SAUSaudi Arabia pop 52.50.0127158See
ZAFSouth African Indian population2.00.010050See
VNMVietnam Kinh2.00.0099101See
CRICosta Rica Amerindians (G)1.60.0080125See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.40.00205266See
CHNChina Zhejiang Han0.00141734See
USAUSA Arizona Gila River Pima0.00053000See
USAUSA NMDP Black South or Central American0.00004889See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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