Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 428 time(s) and present in 390 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
NORNorway Sami0.1550200See
CZECzech Republic Romani pop 217.40.119646See
RUSRussia Sakhalin Island Nivkhi0.104053See
BFABurkina Faso Fulani0.102049See
PAKPakistan Kalash0.094069See
HRVCroatia pop 315.80.0875120See
SWESweden Uppsala16.70.0873300See
RUSRussia Chuvash0.079082See
NORNorway pop 20.0750576See
GBRUnited Kingdom South West0.0740163See
RUSRussia Murmansk Saomi Mixed0.070070See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.069094See
GBRUnited Kingdom Central0.0677135See
SRBSerbia Vojvodina12.00.0660400See
DEUGermany Essen13.20.0660174See
POLPoland pop 312.70.06472907See
SVNSlovenia pop 312.30.0640130See
SWESweden pop 412.00.0626966See
MEXMexico Michoacan Tarasco12.30.0610130See
NORNorway ethnic Norwegians11.60.06024510See
ESPSpain Majorcans Jews0.0600103See
FRAFrance Rennes pop 30.0600200See
GBRUnited Kingdom pop 20.0590101See
MNGMongolia Oold0.0580104See
ESPSpain Ibiza0.057088See
SVKSlovakia pop 20.05674234See
GBRUnited Kingdom East0.0559163See
RUSRussia South Ural Bashkir11.00.0550146See
RUSRussia Samara Region0.05402500See
GEOGeorgia Kurds0.054030See
RUSRussia Tatars0.0535355See
RUSRussia Northwest pop 210.30.0530346See
RUSRussia South Ural Russian9.70.0530207See
GBRUnited Kingdom North0.0522330See
ESPSpain Catalonia Girona0.052088See
RUSRussia Northwest10.10.05181011See
RUSRussia Moscow0.05102650See
THAThailand Northeast pop 20.0510400See
SRBSerbia pop 39.90.05001992See
PRTPortugal Castelo Branco0.0490327See
HRVCroatia pop 20.0490100See
THAThailand Northeast0.049066See
PHLPhilippines National Capital Region0.049051See
BIHBosnia and Herzegovina0.0485134See
ROMRomania pop 39.50.04851469See
RUSRussia South Ural Tatar9.60.0480135See
MKDMacedonia MBMDR - Macedonian9.40.04791283See
ENGEngland Liverpool9.30.04761343See
CMRCameroon Podokwo0.047043See
MEXMexico Nayarit, Tepic0.046497See
USAUSA Caucasian Bethesda9.20.0460307See
MEXMexico Guanajuato, Guanajuato city0.045522See
MEXMexico Colima Rural0.045543See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks8.00.0450112See
ENGEngland Manchester8.80.04501640See
WALWales pop 28.90.045039979See
RUSRussia Moscow Pop 28.80.04492000See
AUTAustria Cord Bloods0.04421368See
FRAFrance Reims0.0440102See
ENGEngland Sheffield8.60.04394755See
USAUSA OPTN Caucasian0.04308525See
PRTPortugal North0.043046See
ENGEngland Lancaster8.40.0429545See
ENGEngland Leeds8.40.04295024See
ENGEngland Newcastle8.30.04242739See
ESPSpain Andalusia0.041099See
MKDMacedonia pop 30.0410172See
MEXMexico Nahuas0.041072See
FRAFrance Grenoble8.10.04061000See
MYSMalaysia Sarawak Bidayuh0.040050See
PAKPakistan Mixed Pathan0.0400100See
ROMRomania pop 20.04006936See
FRAFrance Marseille7.80.03951000See
FRAFrance Bordeaux7.80.0390990See
TWNTaiwan Minnan and Hakka0.0390190See
FRAFrance Rennes pop 47.80.03891000See
MEXMexico Sinaloa, Culiacán0.0388103See
IRLIreland South pop 20.038417624See
INDIndia Jalpaiguri Toto7.50.038240See
MEXMexico Mayan Pop 30.038066See
FRAFrance Grenoble, Nantes and Rennes0.03806094See
BIHBosnia and Herzegovina pop 27.50.0375120See
MARMorocco Casablanca0.0370100See
MEXMexico Morelos, Cuernavaca0.036682See
PRTPortugal Center pop 20.0360562See
ARMArmenia living in Karabakh0.0360445See
MEXMexico Zacatecas, Zacatecas city0.035784See
FRAFrance Lyon7.10.03564813See
MEXMexico Sinaloa Rural0.0355183See
MKDMacedonia MBMDR - Albanian7.00.0352128See
ARGArgentina Corrientes6.40.0350155See
PRTMadeira pop 20.0350173See
PRTAzores Terceira Island0.0350130See
MYSMalaysia pop 20.035062See
ESPSpain Gipuzkoa Basque0.0350100See
ITAItaly Sardinia pop30.0350100See
VENVenezuela Colonia Tovar0.034986See
PRTPortugal Vila Real0.03401167See
MEXMexico Sinaloa Capomos Mayo Yoremes0.033360See
MEXMexico San Luis Potosi, San Luis Potosi city0.033330See
MEXMexico Queretaro, Queretaro city0.033345See
THAThailand pop 40.033016807See
SDNSudan South Nuba6.50.033046See
ARMArmenia Shirak0.033076See
ARMArmenia Ghegharkunik0.0330242See
MEXMexico Colima, Colima city0.032861See
PRTMadeira pop 30.0320538See
ESPSpain Murcia0.0320173See
ITAItaly Bergamo5.90.0320101See
ISRIsrael Ashkenazi Jews pop 20.0320132See
MMRMyanmar Mon6.30.031364See
PRTPortugal South pop 20.03101021See
CHNChina Shanghai0.031026266See
CUBCuba Mixed0.031078See
FRAFrance Southeast6.20.0310130See
ESPSpain North Cantabria0.031083See
MKDMacedonia pop 40.0310216See
KORSouth Korea pop 80.03107096See
PRTPortugal Porto0.03107937See
PRTPortugal North pop 20.03101801See
MEXMexico Sonora Rural0.0305197See
ESPSpain North6.00.0304156See
MEXMexico Sonora, Hermosillo0.030399See
ESPSpain, Castilla y Leon, Northwest,5.70.03021743See
ARMArmenia Syunik0.0300117See
PRTPortugal Braga0.03001971See
AUSAustralia West Caucasian5.80.0300891See
BRABrazil Parana Caucasian5.90.03002775See
MEXMexico Jalisco, Guadalajara city0.02971189See
MEXMexico Durango, Durango city0.0290153See
CHNChina Harbin Manchu0.0290172See
ALBAlbania pop 25.80.0289432See
MEXMexico Mexico City South0.028852See
MEXMexico San Luis Potosi Rural0.028787See
SAUSaudi Arabia5.60.028418See
SDNSudan Central Shaigiya Mixed5.60.028436See
MEXMexico Jalisco Rural0.0282585See
PRTPortugal Santarem0.02803865See
PRTPortugal Viana do Castelo0.0280706See
PRTPortugal Leiria0.02801847See
ARMArmenia Yerevan0.0280445See
MYSMalaysia pop 30.02801445See
CHNChina Harbin Korean0.0280201See
KORSouth Korea pop 10.0280324See
TURTurkey pop 50.0280142See
TURTurkey pop 20.0280228See
MMRMyanmar Shan5.60.027854See
BRABrazil REDOME Santa Catarina0.0277106673See
RUSRussia North Ossetian5.50.0276127See
GRCGreece pop 70.027511250See
BRABrazil REDOME Rio Grande do Sul0.0274241329See
MEXMexico Chihuahua Rural0.0272236See
RUSRussia Transbaikal Territory Buryats5.00.0270150See
BRABrazil Rio Grande do Sul Caucasoid0.02704428See
PRTPortugal Lisbon0.027017420See
PRTPortugal Setubal0.02705268See
MARMorocco pop 20.0270110See
TWNTaiwan Minnan pop 20.02707137See
BRABrazil Parana Cafuzo5.30.0270319See
BRABrazil Parana Mixed race5.40.0270186See
CHNChina Jiangsu Province0.027020248See
BRABrazil Curitiba-Parana Mixed0.0268264See
ENGEngland North West Mixed pop 25.30.0264379See
MKDMacedonia MBMDR - Macedonian Muslims5.30.026376See
BRABrazil REDOME Goias0.026288574See
BRABrazil Rio Grande do Sul Mixed0.0260324See
PRTPortugal Viseu0.02602915See
PRTPortugal Faro0.02601242See
PRTPortugal Coimbra0.02605057See
BRABrazil REDOME Parana0.0256341639See
MEXMexico Guanajuato, Leon0.025678See
INDIndia sub-Himalayan West Bengal Kami5.10.0253158See
ESPSpain Sevilla5.00.0252278See
INDIndia North Gujarat5.00.0252338See
PRTPortugal Evora0.0250737See
PRTPortugal Beja0.0250699See
VENVenezuela Zulia Maracaibo Mixed0.025020See
RUSRussia Northwest pop 35.00.0250100See
ALBAlbanian Kosovo0.0250120See
TWNTaiwan Hakka pop 20.0250714See
GRCGreece North0.0250500See
SCOScotland Orkney4.90.025099See
CHNChina Wuhan5.00.0250121See
MNGMongolia Khalkha0.0250200See
MEXMexico Hidalgo Rural0.024781See
BRABrazil REDOME Minas Gerais0.0242211275See
BRABrazil Sao Paulo Bauru Mixed0.02403542See
ARMArmenia living in Iran0.024085See
ARMArmenia living in USA0.0240233See
PRTPortugal Aveiro0.02405933See
ARGArgentina La Plata5.00.0240100See
GBRUnited Kingdom Orkney0.024088See
MEXMexico Zacatecas, Fresnillo0.0238103See
MEXMexico Jalisco, Zapopan0.0238168See
IRQIraq Arabs4.70.0235149See
BRABrazil REDOME Federal District0.023529549See
MEXMexico Queretaro Rural0.023343See
PRTPortugal Portalegre0.02301254See
CHNChina Shandong Province4.50.02307418See
USAUSA OPTN Hispanic0.02301580See
ARGArgentina Buenos Aires pop 24.50.02301216See
IRQIraq Erbil4.60.0229372See
MEXMexico Mexico City Center0.0227152See
BRABrazil REDOME Rio Grande do Norte0.022546603See
MEXMexico Mestizo pop 40.0223269See
MEXMexico Zacatecas Rural0.0223266See
MEXMexico Veracruz, Poza Rica0.022245See
BRABrazil Minas Gerais State Mixed4.30.02201000See
PRTPortugal Guarda0.0220797See
PRTPortugal Bragança0.0220301See
BRABrazil Paraná Caucasian4.40.0218641See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
BRABrazil REDOME Mato Grosso0.021634649See
BRABrazil REDOME Sao Paulo0.0214800809See
BRABrazil REDOME Alagoas0.021425349See
BRABrazil South East Cord Blood0.021311409See
ECUEcuador Coast Mixed Ancestry0.0210238See
MEXMexico Sonora, Ciudad Obregón0.0210143See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.021096See
BRABrazil Rio Grande do Norte Mestizo0.021012973See
ARGArgentina Cuyo Region4.20.0210420See
MNGMongolia Tsaatan0.0210144See
GRCGreece pop34.10.0207246See
CHLChile Santiago0.0207920See
BRABrazil REDOME Tocantins0.020620692See
MEXMexico Coahuila, Saltillo0.020572See
MEXMexico Nuevo Leon Rural0.0205439See
CHNChina Guangdong Province4.00.0202403See
BRABrazil REDOME Mato Grosso do Sul0.020195667See
BRABrazil REDOME Paraiba0.020143868See
BRABrazil REDOME Rio de Janeiro0.0201139322See
BRABrazil REDOME Rondonia0.020054396See
MYSMalaysia Sarawak Iban0.020051See
VNMVietnam Hanoi0.020050See
USAUSA OPTN Asian0.0200261See
PAKPakistan Burusho0.020092See
ARGArgentina Buenos Aires3.80.0200466See
ITAItaly Rome4.00.0200100See
RUSRussia Arkhangelsk Pomor0.020063See
BRABrazil Pernambuco Mixed0.0200101See
TWNTaiwan Chinese immigrants from North China0.0200152See
MEXMexico Quintana Roo Rural0.020050See
MEXMexico Nuevo Leon, Monterrey city0.0199226See
ITAItaly North Pavia pop 30.0197685See
BRABrazil REDOME Espirito Santo0.019488485See
BRABrazil REDOME Acre0.0192859See
BRABrazil Piaui Mixed0.019021943See
BRABrazil REDOME Maranhao0.019010180See
ITAItaly North Pavia pop 23.60.01902416See
CHNChina Shaanxi Province Han0.019010000See
BRABrazil South Ribeirao Preto0.0190184See
INDIndia North pop 30.0190587See
CHNChina Guangzhou Han0.0190106See
ESPSpain North Cabuerniga0.019095See
PAKPakistan Brahui0.0190104See
BFABurkina Faso Mossi0.019053See
BRABrazil REDOME Piaui0.018946140See
BRABrazil REDOME Ceara0.0186101217See
BRABrazil REDOME Roraima0.01854140See
COLColombia Barranquilla0.0185188See
MEXMexico Tabasco, Villahermosa0.018382See
SAUSaudi Arabia pop 43.40.0181499See
CHNChina Shandong Province Linqu County3.60.0181139See
SENSenegal Dakar3.60.0180112See
ESPSpain Majorca0.0180407See
MEXMexico Sinaloa Mestizo0.018056See
BRABrazil Para State1.80.01805000See
BRABrazil REDOME Pernambuco0.017892332See
BRABrazil REDOME Para0.017672637See
MEXMexico Michoacan Rural0.0172348See
IRNIran pop 40.0170855See
ITAItaly Lombardy3.40.0170674See
KURIraq Kurdistan Region3.30.0170209See
IRNIran Royan Cord Blood Bank3.30.017015600See
MEXMexico Mexico City Mestizo0.0170121See
BGDBangladesh Dhaka Bangalee0.0170141See
ISRIsrael Jews pop 23.40.017023000See
ENGEngland London Ashkenazi Jews0.0170500See
ESPSpain Majorca and Minorca0.017090See
MEXMexico Chihuahua Chihuahua City0.0168119See
MEXMexico Mexico City Metropolitan Area Rural0.0164150See
BRABrazil REDOME Amapa0.016217864See
MEXMexico Mexico City Mestizo pop 30.0160256See
MEXMexico Nayarit Rural0.015664See
BRABrazil REDOME Bahia0.015647399See
MEXMexico Guanajuato Rural0.0153162See
MEXMexico Baja Californa, Mexicali0.0150100See
GAZGaza Palestinians0.0150165See
ARMArmenia Lori0.0150102See
FRAFrance Corsica Island0.0150100See
PAKPakistan Baloch0.015066See
BRABrazil Sao Paulo Mixed0.30.0150239See
TWNTaiwan Chinese immigrants from South China0.0150172See
MEXMexico Mexico City West0.014933See
BRABrazil REDOME Amazonas0.014724129See
MEXMexico Tabasco Rural0.0141142See
TWNTaiwan Chinese immigrants from Middle China0.0140211See
TWNTaiwan Aborigine0.0140111See
CUBCuba Mixed pop 20.0140189See
BRABrazil REDOME Sergipe0.01397321See
MEXMexico Chihuahua, Ciudad Juarez0.0139106See
MEXMexico Guerrero state0.0139144See
MEXMexico Coahuila Rural0.0138216See
ITAItaly pop 62.70.0136184See
CZECzech Republic Kurd2.70.013574See
MEXMexico Puebla, Puebla city0.01331994See
ECUEcuador Mixed Ancestry0.01321173See
BRABrazil Parana Japanese3.00.0131192See
BRABrazil Para Cord Blood Unit2.60.0131841See
BRABrazil Parana Afro Brazilian2.60.013077See
ITAItaly South Campania Region2.60.01301089See
ECUEcuador Amazonia Mixed Ancestry0.012839See
MEXMexico Durango Rural0.0122326See
ECUEcuador Andes Mixed Ancestry0.0121824See
ARMArmenia living in Lebanon0.0120368See
ITAItaly North Pavia0.012081See
RUSRussia Nenet Mixed0.012055See
BRABrazil Rio Grande do Sul Black0.0120248See
MEXMexico Tamaulipas Rural0.0119125See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
ESPSpain Minorca0.011094See
USAUSA African American Bethesda2.10.0110187See
USAUSA OPTN African American0.01101510See
MMRMyanmar Bamar2.20.010946See
MEXMexico Campeche Rural0.010647See
COLColombia Wayu from Guajira Peninsula0.010448See
MEXMexico Baja California Rural0.010050See
MEXMexico Coahuila, Torreon0.0100396See
MNGMongolia Khalkha pop 20.0100202See
DZAAlgeria pop 22.00.0100106See
TTOTrinidad South Asian0.010087See
GRCGreece Crete0.0100135See
VENVenezuela Caracas Mestizo0.010050See
MEXMexico Puebla Mestizo0.010099See
MEXMexico Michoacan, Morelia0.0099150See
MEXMexico Veracruz Rural0.0092539See
MEXMexico Mexico City Tlalpan1.80.0091330See
MEXMexico Puebla Rural0.0090833See
ISRIsrael Moroccan Jews0.0090113See
LKASri Lanka Colombo Sinhalese0.0090101See
MEXMexico Veracruz, Veracruz city0.0087171See
MEXMexico Tlaxcala Rural0.0084830See
MEXMexico Chiapas Rural0.0083121See
MEXMexico Tlaxcala, Tlaxcala city0.0083181See
MEXMexico Veracruz, Xalapa0.0080187See
IRNIran pop 10.008064See
SAUSaudi Arabia pop 20.0070383See
TTOTrinidad African0.007067See
PERPeru Arequipa Mestizo1.40.0070168See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
MEXMexico Baja California, La Paz0.006775See
MEXMexico Mexico City East0.006379See
MEXMexico Mexico City North0.0060751See
BOLBolivia La Paz Aymaras0.006087See
MEXMexico Veracruz Xalapa1.20.006084See
ESPSpain Arratia Valley Basque0.006083See
CHNChina Yunnan Province Naxi0.0060118See
MNGMongolia Tarialan Khoton0.006085See
JPNJapan pop 20.0060916See
AREUnited Arab Emirates pop 21.10.0060373See
JPNJapan Kyoto and Osaka0.0060165See
SDNSudan Khartoum0.005198See
MEXMexico Yucatan, Merida0.0051192See
BRABrazil Belem Mixed1.00.0050100See
JPNJapan Hyogo Osaka and Nagano0.0050195See
ESPSpain Pas Valley0.005088See
PAKPakistan Mixed Sindhi0.0050101See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MEXMexico Oaxaca, Oaxaca city0.0033151See
RUSRussia Belgorod region0.70.0033153See
GHAGhana Accre Asutuare Akan0.0020429See
JPNJapan Tohoku Region0.0020322See
MEXMexico Oaxaca Rural0.0010485See
MEXMexico Morelos Rural0.000030See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Aguascalientes state0.000095See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Quintana Roo, Cancun0.000048See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
TZATanzania Dodoma Kongwa0.0000212See
CMRCameroon Ewondo0.000038See
CMRCameroon Bamileke 20.000035See
CMRCameroon Uldeme0.000035See
ITAItaly North pop 30.00.000097See
ZAFSouth Africa Natal Zulu0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
MEXMexico Huasteca Region Teenek0.000055See
MNGMongolia Ulaanbaatar Khalkha0.000041See
PAKPakistan Karachi Parsi0.000091See
CHNChina Yunnan Province Han pop 20.0000129See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
BFABurkina Faso Rimaibe0.000047See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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