Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 70 time(s) and present in 69 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica Guaymi NA-DHS_10 (G)77.80.416718See
CANCanada Ojibwa NA-DHS_4 (G)53.30.266716See
GTMGuatemala Kaqchikel NA-DHS_8 (G)31.60.184219See
CPVCape Verde Northwestern Islands0.174062See
MEXMexico Hidalgo Mezquital Valley/ Otomi29.20.173672See
USAUSA Arizona Gila River Pima0.16833000See
CANCanada Cree NA-DHS_3 (G)27.80.166718See
CANCanada Chipewyan NA-DHS_2 (G)28.00.160025See
CRICosta Rica Amerindians (G)29.40.1550125See
GNBGuinea Bissau0.144065See
CRICosta Rica Cabecar NA-DHS_9 (G)26.30.131619See
MEXMexico Mixtec NA-DHS_5 (G)25.00.125020See
MEXMexico Mixe NA-DHS_6 (G)20.00.100020See
MEXMexico Guadalajara Mestizo pop 20.0970103See
CHNChina Yunnan Province Wa0.0920119See
NICNicaragua Mestizo (G)17.40.0900155See
CPVCape Verde Southeastern Islands0.089062See
RUSRussian Federation Vologda Region17.60.0882119See
CRICosta Rica Central Valley Mestizo (G)16.70.0880221See
RUSRussia Bashkortostan, Tatars15.10.0833192See
IRNIran Baloch0.0810100See
ESPSpain, Canary Islands, Gran canaria island15.40.0791215See
BRABrazil Rio de Janeiro Black0.074668See
INDIndia Kerala Malayalam speaking14.30.0730356See
COLColombia Kogi NA-DHS_17 (G)14.30.071415See
CRICosta Rica African -Caribbean (G)13.80.0690102See
USAUSA Mexican American Mestizo0.0680553See
GRCGreece Athens13.60.06781888See
RUSRussia Belgorod region13.10.0654153See
USAUSA Eastern European0.0650558See
RUSRussia Nizhny Novgorod, Russians12.30.06421510See
RUSRussia Tundra Nentsi NA-DHS_1 (G)12.50.062516See
COLColombia Zenu NA-DHS_18 (G)12.50.062516See
ZAFSouth Africa Caucasians0.0620102See
BRABrazil Barra Mansa Rio State Black0.061673See
USAUSA San Francisco Caucasian0.0570220See
BRABrazil Rio de Janeiro Parda0.0559170See
BRABrazil Barra Mansa Rio State Caucasian0.0556405See
USAUSA Italy Ancestry0.0530273See
INDIndia Andhra Pradesh Telugu Speaking10.20.0511186See
ZAFSouth African Indian population8.00.050050See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
CRICosta Rica Guanacaste Mestizo (G)10.00.0500110See
POLPoland BMR9.70.049923595See
ENGEngland Blood Donors of Mixed Ethnicity9.40.0491519See
INDIndia Karnataka Kannada Speaking9.80.0490174See
BRABrazil Rio de Janeiro Caucasian0.0489521See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
MARMorocco Nador Metalsa pop 20.043073See
RUSRussia Bashkortostan, Bashkirs8.30.0417120See
MARMorocco Atlantic Coast Chaouya0.034098See
MARMorocco Settat Chaouya6.80.034098See
MEXMexico Zapotec NA-DHS_7 (G)5.90.029420See
SAUSaudi Arabia pop 6 (G)0.027928927See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
CHNChina Zhejiang Han0.02451734See
VNMVietnam Kinh4.00.0198101See
CHNChina North Han0.0190105See
HKGHong Kong Chinese HKBMDR HLA 11 loci3.70.01875266See
ZAFSouth African Black2.80.0141142See
IDNIndonesia Java pop 20.014036See
CHNChina Yunnan Province Jinuo0.0140109See
USAUSA Spain Ancestry0.0130279See
ZAFSouth African Mixed ancestry2.00.010050See
CHNChina Jingpo Minority1.90.0100105See
IDNIndonesia Sundanese and Javanese0.0030201See
KORSouth Korea pop 30.0000485See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional