Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 248 time(s) and present in 217 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GEOGeorgia Tibilisi0.1110109See
INDIndia North pop 20.106072See
INDIndia New Delhi0.091071See
INDIndia West Bhil0.090050See
GEOGeorgia Svaneti Region Svan0.088080See
INDIndia Central UCBB17.50.08734204See
GEOGeorgia Tibilisi Kurd0.086031See
INDIndia Andhra Pradesh Golla0.0820111See
INDIndia East UCBB15.90.07952403See
INDIndia South UCBB15.60.077911446See
INDIndia North UCBB15.40.07705849See
SGPSingapore SGVP. Indian INS0.075086See
USAUSA NMDP South Asian Indian0.0720185391See
ZAFSouth Africa Natal Tamil0.071051See
ESPSpain Andalusia Romani0.071099See
INDIndia West UCBB13.80.06925829See
INDIndia Tamil Nadu0.06732492See
INDIndia Delhi pop 213.20.066090See
INDIndia Northeast UCBB12.20.0608296See
LKASri Lanka Colombo11.30.0600714See
CHNChina Yunnan Province Wa0.0590119See
SRBSerbia pop 210.80.0590102See
HRVCroatia pop 40.05814000See
MYSMalaysia Peninsular Indian11.10.0572271See
INDIndia Mumbai Maratha0.056091See
CHESwitzerland Aargau-Solothurn0.05521838See
DEUGermany DKMS - Turkey minority0.05444856See
USAUSA NMDP Southeast Asian0.051227978See
DEUGermany DKMS - Greece minority0.05021894See
ISRIsrael Arab Druze0.0500101See
DEUGermany DKMS - Bosnia and Herzegovina minority0.04961028See
RUSRussia Bering Island Aleuts0.0481104See
BRABrazil Belo Horizonte Caucasian9.50.047095See
CHESwitzerland Sion0.0454832See
CHESwitzerland Zurich0.04524875See
BGRBulgaria Romani0.045013See
CHESwitzerland St Gallen0.04482113See
DEUGermany DKMS - Croatia minority0.04422057See
PRTPortugal Azores Terceira Island7.90.0439130See
GRCGreece pop 60.0425242See
GRCGreece pop 88.40.042283See
INDIndia Khandesh Region Pawra0.040050See
DEUGermany DKMS - Romania minority0.03931234See
PRTAzores Terceira Island0.0390130See
ITAItaly pop 50.0380975See
CHESwitzerland Lugano0.03601169See
ARMArmenia combined Regions0.0350100See
CHESwitzerland Lausanne0.0348993See
CHESwitzerland Graubunden0.0340759See
AREUnited Arab Emirates Pop 10.0340570See
POLPoland DKMS0.034020653See
CZECzech Republic NMDR0.03155099See
SGPSingapore Javaneses0.031051See
USAUSA NMDP Middle Eastern or North Coast of Africa0.031070890See
USAUSA NMDP Caribean Indian0.030014339See
CHESwitzerland Basel0.02921888See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0280146See
USAUSA Caucasian Bethesda5.40.0270307See
DEUGermany DKMS - Italy minority0.02631159See
PRTAzores Oriental Islands0.026043See
AUSAustralia New South Wales Caucasian0.0260134See
CHESwitzerland Geneva pop 20.02531267See
RUSRussia Karelia0.02531075See
USAUSA Caucasian pop 40.02511070See
DEUGermany DKMS - Portugal minority0.02511176See
CHNChina Tibet Region Tibetan0.0250158See
INDIndia Tamil Nadu Nadar0.025061See
DEUGermany pop 80.024639689See
IDNIndonesia Java Western4.70.0240236See
USAUSA Asian pop 20.02411772See
CUBCuba Mixed Race4.80.024042See
USAUSA Italy Ancestry0.0240273See
DEUGermany DKMS - Austria minority0.02391698See
USAUSA NMDP Caribean Hispanic0.0238115374See
USAUSA Spain Ancestry0.0230279See
CHNChina Shanxi HIV negative0.023022See
USAUSA Eastern European0.0230558See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,4.50.02234335See
CHESwitzerland Bern0.02223545See
PRTPortugal North0.022046See
USAUSA Philadelphia Caucasian4.40.0220141See
DEUGermany DKMS - German donors0.02183456066See
DEUGermany pop 60.02148862See
DEUGermany DKMS - Spain minority0.02031107See
FRAFrance French Bone Marrow Donor Registry0.020142623See
CHNChina Inner Mongolia Region0.0200102See
PRTPortugal Center0.020050See
AREUnited Arab Emirates Abu Dhabi0.019252See
MYSMalaysia Mandailing3.70.019027See
FRAFrance Southeast3.80.0190130See
USAUSA Caucasian pop 20.0190265See
USAUSA San Antonio Caucasian0.0181222See
DEUGermany DKMS - France minority0.01811406See
CHNChina Qinghai Province Hui0.0180110See
PRTAzores Central Islands0.018059See
MYSMalaysia Kelantan3.60.018028See
MYSMalaysia Champa3.50.017029See
USAUSA European American pop 20.01701245See
SAUSaudi Arabia Guraiat and Hail3.40.0170213See
DEUGermany DKMS - United Kingdom minority0.01631043See
USAUSA NMDP European Caucasian0.01621242890See
CHNChina Sichuan HIV negative0.015034See
CHNChina Yunnan Province Han0.0150101See
DEUGermany DKMS - Netherlands minority0.01491374See
MEXMexico Tixcacaltuyub Maya0.014967See
USAUSA NMDP Hispanic South or Central American0.0147146714See
CHESwitzerland Luzern0.01451553See
CHNChina Jiangsu Province Han0.0143334See
MARMorocco Nador Metalsa pop 20.014073See
CUBCuba Caucasian2.90.014070See
USAUSA Hispanic pop 20.01381999See
NLDNetherlands Leiden0.01301305See
USAUSA San Diego2.60.0130496See
USAUSA NMDP Mexican or Chicano0.0130261235See
SGPSingapore SGVP Malay MAS0.012089See
CHNChina Beijing Shijiazhuang Tianjian Han0.0120618See
ENGEngland North West2.30.0120298See
COLColombia Bogotá Cord Blood2.40.01201463See
ISRIsrael Bukhara Jews0.01132317See
USAUSA NMDP American Indian South or Central America0.01105926See
USAUSA NMDP Alaska Native or Aleut0.01101376See
RUSRussia Tuva pop 20.0110169See
USAUSA Hispanic0.0110234See
MEXMexico Mexico City Mestizo pop 20.0107234See
TUNTunisia Gabes0.010595See
THAThailand pop 30.010049See
IRLIreland South2.00.0100250See
IRNIran Baloch0.0100100See
PRTPortugal South0.010049See
HKGHong Kong Chinese1.90.0100569See
USAUSA NMDP North American Amerindian0.009535791See
DEUGermany DKMS - China minority0.00921282See
USAUSA Mexican American Mestizo0.0090553See
USAUSA San Francisco Caucasian0.0090220See
CZECzech Republic0.0090106See
CHNChina Jiangsu Han0.00903238See
HKGHong Kong Chinese BMDR0.00837595See
USAUSA North American Native0.0080187See
USAUSA Asian0.0080358See
USAUSA South Texas Hispanic0.0080194See
CPVCape Verde Northwestern Islands0.008062See
CPVCape Verde Southeastern Islands0.008062See
SWESweden Southern Sami0.0080130See
HKGHong Kong Chinese cord blood registry0.00803892See
CHNChina Hubei Han1.60.00793732See
USAUSA NMDP Chinese0.007999672See
NLDNetherlands UMCU1.60.007864See
USAUSA NMDP Hawaiian or other Pacific Islander0.007711499See
CHLChile Mapuche0.007766See
BRABrazil Puyanawa1.30.0070150See
SWESweden Northern Sami0.0070154See
MYSMalaysia Peninsular Malay1.30.0063951See
NICNicaragua Managua1.20.0060339See
MEXMexico Veracruz Xalapa1.20.006084See
SGPSingapore Chinese Han0.006094See
UGAUganda Kampala0.0060161See
USAUSA NMDP Vietnamese0.005743540See
KORSouth Korea pop 100.00524128See
NZLNew Zealand Maori with Admixed History1.00.0050105See
CHNChina North Han0.0050105See
MEXMexico Guadalajara Mestizo pop 20.0050103See
USAUSA African American Bethesda1.10.0050187See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
NIRIreland Northern0.90.00501000See
SGPSingapore Riau Malay0.0050132See
SDNSudan Mixed1.00.0050200See
ISRIsrael Georgia Jews0.00484471See
USAUSA NMDP Korean0.004677584See
ISRIsrael Poland Jews0.004513871See
USAUSA NMDP Filipino0.004450614See
USAUSA NMDP Caribean Black0.004333328See
ISRIsrael USSR Jews0.004345681See
CHNChina Marrow Donor Registry0.0040600See
CHNChina Canton Han0.0040264See
CHNChina South Han0.0040284See
USAUSA African American pop 80.0040605See
KORSouth Korea pop 30.0040485See
USAUSA African American pop 40.00352411See
MEXMexico Mexico City Mestizo population0.0035143See
ISRIsrael Kavkazi Jews0.00332840See
ISRIsrael Iran Jews0.00338153See
TWNTaiwan Tzu Chi Morrow Donor Registry0.003246682See
ISRIsrael USA Jews0.00316058See
UGAUganda Kampala pop 20.0030175See
VNMVietnam Hanoi Kinh pop 20.0030170See
USAUSA African American pop 30.0030564See
SGPSingapore Chinese0.70.0030149See
ISRIsrael Arab pop 20.003012301See
ISRIsrael Druze0.00275914See
MYSMalaysia Peninsular Chinese0.50.0026194See
ISRIsrael Argentina Jews0.00234307See
ISRIsrael Ashkenazi Jews pop 30.00224625See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0021233See
USAUSA NMDP African American pop 20.0020416581See
USAUSA NMDP African0.001628557See
ISRIsrael Tunisia Jews0.00159070See
ISRIsrael Morocco Jews0.001236718See
ISRIsrael Iraq Jews0.001113270See
TWNTaiwan pop 20.0010364See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
TWNTaiwan Han Chinese0.0010504See
ISRIsrael Libya Jews0.00093739See
ISRIsrael YemenJews0.000915542See
USAUSA NMDP Japanese0.000524582See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
SGPSingapore SGVP Chinese CHS0.000096See
CHNChina Yunnan Province Jinuo0.0000109See
ZAFSouth Africa Natal Zulu0.00.0000100See
INDIndia West Coast Parsi0.000050See
MEXMexico Mestizo0.00.000041See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
PHLPhilippines Ivatan0.00.000050See
GNBGuinea Bissau0.000065See
AUSAustralia Yuendumu Aborigine0.0000191See
ZMBZambia Lusaka0.000044See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
USAUSA Alaska Yupik0.0000252See
ITAItaly North pop 30.00.000097See
MARMorocco Settat Chaouya0.00.000098See
USAUSA African American0.0000252See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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