Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 235 time(s) and present in 200 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Ashkenazi Jews pop 30.16724625See
ISRIsrael Poland Jews0.166213871See
ISRIsrael USA Jews0.15226058See
ISRIsrael Bukhara Jews0.14242317See
ISRIsrael Argentina Jews0.13494307See
ISRIsrael USSR Jews0.115745681See
ISRIsrael Georgia Jews0.09644471See
ISRIsrael Morocco Jews0.091036718See
IRNIran Yazd0.071456See
ITAItaly North pop 313.30.067097See
PRTAzores Oriental Islands0.064043See
ISRIsrael Iran Jews0.05478153See
PRTAzores Central Islands0.054059See
SDNSudan Mixed9.50.0530200See
ISRIsrael Kavkazi Jews0.05212840See
DEUGermany DKMS - Croatia minority0.05082057See
DEUGermany DKMS - Bosnia and Herzegovina minority0.04821028See
CZECzech Republic0.0470106See
MKDMacedonia pop 40.0460216See
ISRIsrael YemenJews0.045715542See
SRBSerbia pop 28.80.0440102See
PRTPortugal Azores Terceira Island8.80.0439130See
HRVCroatia pop 40.04394000See
ISRIsrael Arab pop 20.043612301See
CUBCuba Caucasian8.60.043070See
ISRIsrael Iraq Jews0.042513270See
IRNIran Kurd pop 20.042060See
IRNIran Saqqez-Baneh Kurds0.041760See
IRNIran Tabriz Azeris0.041297See
DEUGermany DKMS - Turkey minority0.04124856See
ESPSpain Andalusia0.041099See
ISRIsrael Tunisia Jews0.04099070See
ARMArmenia combined Regions0.0400100See
PRTAzores Terceira Island0.0390130See
GEOGeorgia Svaneti Region Svan0.038080See
GRCGreece pop 60.0377242See
CZECzech Republic NMDR0.03705099See
BRABrazil Puyanawa7.30.0370150See
USAUSA Philadelphia Caucasian7.40.0370141See
USAUSA NMDP Middle Eastern or North Coast of Africa0.036970890See
RUSRussia Karelia0.03651075See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.10.03624335See
CHESwitzerland Basel0.03611888See
POLPoland DKMS0.034920653See
DEUGermany DKMS - Romania minority0.03491234See
MEXMexico Chihuahua Chihuahua City Pop 26.80.034188See
DEUGermany DKMS - Italy minority0.03371159See
DEUGermany DKMS - Greece minority0.03301894See
BRABrazil Belo Horizonte Caucasian5.30.032095See
IRNIran Gorgan0.031064See
DEUGermany DKMS - Spain minority0.03071107See
CHESwitzerland Lugano0.02991169See
DEUGermany DKMS - Portugal minority0.02931176See
ITAItaly pop 50.0290975See
CHESwitzerland St Gallen0.02762113See
ISRIsrael Druze0.02675914See
CHESwitzerland Geneva pop 20.02671267See
DEUGermany DKMS - Austria minority0.02651698See
CHNChina Uyghur HIV negative0.026019See
USAUSA Eastern European0.0260558See
USAUSA Caucasian pop 20.0250265See
USAUSA European American pop 20.02501245See
DEUGermany pop 80.024639689See
DEUGermany DKMS - France minority0.02451406See
CHESwitzerland Lausanne0.0244993See
CHESwitzerland Aargau-Solothurn0.02421838See
GRCGreece pop 84.80.024183See
TUNTunisia pop 30.0230104See
COLColombia Bogotá Cord Blood4.40.02291463See
DEUGermany DKMS - German donors0.02163456066See
COLColombia North Chimila Amerindians0.021247See
TUNTunisia Gabes0.021095See
USAUSA San Francisco Caucasian0.0210220See
USAUSA NMDP European Caucasian0.02091242890See
AUSAustralia Cape York Peninsula Aborigine0.0200103See
USAUSA NMDP Hispanic South or Central American0.0199146714See
FRAFrance French Bone Marrow Donor Registry0.019442623See
COLColombia North Wiwa El Encanto0.019252See
AREUnited Arab Emirates Abu Dhabi0.019252See
RUSRussia Bering Island Aleuts0.0192104See
USAUSA Hispanic pop 20.01931999See
CHESwitzerland Zurich0.01914875See
CHNChina Canton Han0.0190264See
FRAFrance Southeast3.80.0190130See
DEUGermany pop 60.01868862See
USAUSA NMDP Mexican or Chicano0.0183261235See
USAUSA NMDP Caribean Hispanic0.0182115374See
USAUSA Caucasian pop 40.01771070See
USAUSA Hispanic0.0170234See
NLDNetherlands Leiden0.01701305See
DEUGermany DKMS - United Kingdom minority0.01681043See
CHESwitzerland Graubunden0.0163759See
USAUSA NMDP Caribean Indian0.016014339See
SAUSaudi Arabia pop 6 (G)0.015828927See
CHLChile Mapuche0.015466See
CHLChile Santiago Mixed3.00.015170See
NICNicaragua Managua3.00.0151339See
MEXMexico Guadalajara Mestizo pop 20.0150103See
CHNChina Guangzhou0.0150102See
AUSAustralia New South Wales Caucasian0.0150134See
ZAFSouth Africa Caucasians0.0150102See
DEUGermany DKMS - Netherlands minority0.01461374See
CHESwitzerland Bern0.01423545See
CHNChina Yunnan Province Lisu0.0140111See
MEXMexico Mexico City Mestizo population0.0140143See
JORJordan Amman0.0140146See
MARMorocco Nador Metalsa pop 20.014073See
ISRIsrael Libya Jews0.01343739See
CHESwitzerland Sion0.0131832See
AREUnited Arab Emirates Pop 10.0130570See
USAUSA NMDP American Indian South or Central America0.01305926See
USAUSA South Texas Hispanic0.0130194See
MEXMexico Mexico City Mestizo pop 20.0128234See
MEXMexico Mestizo2.40.012041See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
MEXMexico Veracruz Xalapa2.40.011984See
USAUSA North American Native0.0110187See
USAUSA NMDP North American Amerindian0.010235791See
USAUSA San Diego1.90.0100496See
PRTPortugal South0.010049See
MEXMexico Oaxaca Mixtec0.0100103See
INDIndia North pop 20.010072See
CHNChina North Han0.0100105See
ESPSpain Andalusia Romani0.010099See
HKGHong Kong Chinese1.80.0090569See
CHNChina Qinghai Province Hui0.0090110See
NIRIreland Northern1.80.00901000See
CHESwitzerland Luzern0.00881553See
CHNChina Beijing0.008067See
CPVCape Verde Southeastern Islands0.008062See
IRLIreland South1.60.0080250See
RUSRussia Tuva pop 20.0080169See
STPSao Tome Island Forro0.008066See
NLDNetherlands UMCU1.60.007864See
MEXMexico Oaxaca Zapotec0.007090See
MARMorocco Settat Chaouya1.40.007098See
MARMorocco Atlantic Coast Chaouya0.007098See
CHNChina Beijing Shijiazhuang Tianjian Han0.0070618See
USAUSA NMDP Alaska Native or Aleut0.00701376See
UGAUganda Kampala0.0060161See
USAUSA San Antonio Caucasian0.0060222See
ARGArgentina Rosario Toba1.20.006086See
MYSMalaysia Peninsular Chinese1.00.0052194See
NZLNew Zealand Maori with Admixed History1.00.0050105See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
INDIndia Delhi pop 21.10.005090See
CHNChina Inner Mongolia Region0.0050102See
HKGHong Kong Chinese BMDR0.00477595See
INDIndia North UCBB0.90.00475849See
MEXMexico Mexico City Tlalpan0.90.0045330See
USAUSA Asian pop 20.00451772See
USAUSA NMDP Southeast Asian0.004327978See
HKGHong Kong Chinese cord blood registry0.00423892See
USAUSA NMDP Chinese0.004199672See
USAUSA African American0.0040252See
USAUSA Asian0.0040358See
CHNChina Jiangsu Han0.00403238See
CHNChina Yunnan Bulang0.0040116See
USAUSA NMDP Hawaiian or other Pacific Islander0.003411499See
INDIndia Central UCBB0.70.00334204See
CHNChina Hubei Han0.60.00323732See
INDIndia Tamil Nadu0.00322492See
DEUGermany DKMS - China minority0.00311282See
CHNChina Marrow Donor Registry0.0030600See
USAUSA NMDP South Asian Indian0.0028185391See
USAUSA NMDP African0.002628557See
USAUSA NMDP Caribean Black0.002633328See
USAUSA NMDP African American pop 20.0022416581See
INDIndia West UCBB0.40.00215829See
USAUSA African American pop 80.0020605See
USAUSA NMDP Vietnamese0.001943540See
USAUSA NMDP Filipino0.001750614See
USAUSA African American pop 40.00172411See
MYSMalaysia Peninsular Malay0.30.0016951See
USAUSA NMDP Korean0.001277584See
USAUSA NMDP Japanese0.001024582See
USAUSA African American pop 30.0010564See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
TWNTaiwan pop 20.0010364See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000846682See
INDIndia South UCBB0.10.000511446See
ISRIsrael Ethiopia Jews0.00045928See
INDIndia East UCBB0.10.00042403See
KORSouth Korea pop 100.00024128See
JPNJapan pop 160.000218604See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
KORSouth Korea pop 30.0000485See
MLIMali Bandiagara0.0000138See
PHLPhilippines Ivatan0.00.000050See
PRTPortugal North0.000046See
PRTPortugal Center0.000050See
GNBGuinea Bissau0.000065See
CHNChina Tibet Region Tibetan0.0000158See
AUSAustralia Yuendumu Aborigine0.0000191See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CUBCuba Mixed Race0.00.000042See
CPVCape Verde Northwestern Islands0.000062See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
STPSao Tome Island Angolar0.000032See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Alaska Yupik0.0000252See
ZMBZambia Lusaka0.000044See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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