Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 35 time(s) and present in 31 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Hidalgo Mezquital Valley/ Otomi36.10.222272See
RUSRussian Federation Vologda Region8.40.0420119See
USAUSA Arizona Gila River Pima0.04123000See
CHNChina Zhejiang Han0.02831734See
ESPSpain, Canary Islands, Gran canaria island5.10.0256215See
USAUSA San Francisco Caucasian0.0230220See
INDIndia Kerala Malayalam speaking3.70.0200356See
VNMVietnam Kinh4.00.0198101See
GRCGreece Athens3.30.01641888See
POLPoland BMR3.10.015823595See
HKGHong Kong Chinese HKBMDR HLA 11 loci3.10.01535266See
BRABrazil Rio de Janeiro Black0.014968See
INDIndia Karnataka Kannada Speaking2.90.0140174See
INDIndia Andhra Pradesh Telugu Speaking2.70.0134186See
RUSRussia Belgorod region2.60.0131153See
RUSRussia Nizhny Novgorod, Russians2.50.01261510See
BRABrazil Barra Mansa Rio State Caucasian0.0123405See
USAUSA New Mexico Canoncito Navajo0.012042See
BRABrazil Rio de Janeiro Parda0.0118170See
BRABrazil Rio de Janeiro Caucasian0.0115521See
RUSRussia Bashkortostan, Tatars2.10.0104192See
MEXMexico Guadalajara Mestizo pop 20.0100103See
RUSRussia Bashkortostan, Bashkirs1.70.0083120See
ENGEngland Blood Donors of Mixed Ethnicity1.50.0077519See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
CHNChina Jingpo Minority1.00.0050105See
CRICosta Rica Amerindians (G)0.80.0040125See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
CHNChina South Han0.0020284See
SAUSaudi Arabia pop 6 (G)0.001728927See
USAUSA NMDP Black South or Central American0.00074889See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa pop 20.000073See
CHNChina North Han0.0000105See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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