Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 395 time(s) and present in 341 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Taroko58.20.355055See
TWNTaiwan Atayal60.40.3490106See
TWNTaiwan Paiwan58.80.333051See
TWNTaiwan Ami55.10.327098See
TWNTaiwan Saisiat54.90.314051See
ASMAmerican Samoa0.290051See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.2511233See
TWNTaiwan Thao46.70.250030See
NZLNew Zealand Polynesians with Full Ancestry42.90.238021See
TWNTaiwan pop 20.2230364See
TWNTaiwan Tzu Chi Cord Blood Bank0.2200710See
TWNTaiwan Pazeh40.00.218055See
TWNTaiwan Hakka40.00.218055See
TWNTaiwan Bunun39.60.2130101See
TWNTaiwan Han Chinese0.2110504See
TWNTaiwan pop 30.2070212See
NZLNew Zealand Polynesians with Admixed History37.00.204027See
SGPSingapore SGVP Chinese CHS0.204096See
TWNTaiwan Minnan pop 134.30.2010102See
TWNTaiwan Rukai34.00.190050See
CHLChile Easter Island0.190021See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.186057See
AUSAustralia Kimberly Aborigine0.184041See
TWNTaiwan Tzu Chi Morrow Donor Registry0.181646682See
TWNTaiwan Tsou35.30.176051See
SGPSingapore Chinese28.20.1750149See
AUSAustralia Groote Eylandt Aborigine0.173075See
PHLPhilippines Ivatan30.00.170050See
TWNTaiwan Puyuma26.00.170050See
HKGHong Kong Chinese cord blood registry0.15643892See
CHNChina Marrow Donor Registry0.1550600See
USAUSA NMDP Hawaiian or other Pacific Islander0.154311499See
USAUSA NMDP Chinese0.153899672See
HKGHong Kong Chinese28.00.1520569See
HKGHong Kong Chinese BMDR0.15167595See
CHNChina South Han0.1490284See
CHNChina Canton Han0.1440264See
CHNChina Hubei Han28.20.14093732See
SWESweden Northern Sami0.1400154See
CHNChina Guangxi Region Maonan0.1340108See
CHNChina Guangzhou0.1300102See
CHNChina Beijing0.129067See
SGPSingapore Chinese Han0.128094See
TWNTaiwan Siraya25.50.127051See
NCLNew Caledonia0.125065See
CHNChina Yunnan Province Nu0.1220107See
MYSMalaysia Peninsular Chinese22.70.1211194See
CHNChina Shanxi HIV negative0.114022See
SGPSingapore Javaneses0.112051See
NZLNew Zealand Maori with Full Ancestry21.70.109046See
CHNChina Sichuan HIV negative0.103034See
CHNChina Guizhou Province Bouyei0.1030109See
SWESweden Southern Sami0.1010130See
CHNChina Jiangsu Province Han0.1010334See
CHNChina Yunnan Hani0.1000150See
MYSMalaysia Patani20.00.100025See
DEUGermany DKMS - China minority0.09601282See
USAUSA NMDP Filipino0.092450614See
CHNChina Yunnan Province Jinuo0.0920109See
PNGPapua New Guinea East New Britain Rabaul0.092060See
USAUSA Asian0.0920358See
CHNChina Yunnan Bulang0.0910116See
CHNChina Yunnan Province Wa0.0880119See
PNGPapua New Guinea Karimui Plateau Pawaia0.088080See
CHNChina Guizhou Province Shui0.0830153See
MYSMalaysia Jelebu Temuan0.083025See
CHNChina Beijing Shijiazhuang Tianjian Han0.0810618See
AUSAustralia Cape York Peninsula Aborigine0.0800103See
USAUSA Asian pop 20.07981772See
AUSAustralia New South Wales Caucasian0.0790134See
NLDNetherlands UMCU15.60.078164See
ISRIsrael Libya Jews0.07613739See
CHNChina Guizhou Province Miao pop 20.072085See
CHNChina Yunnan Province Lisu0.0720111See
NZLNew Zealand Maori with Admixed History14.30.0710105See
THAThailand pop 30.071049See
USAUSA Caucasian pop 40.07081070See
DEUGermany DKMS - Netherlands minority0.07061374See
NLDNetherlands Leiden0.06901305See
USAUSA South Dakota Lakota Sioux0.0690302See
USAUSA Caucasian pop 20.0680265See
USAUSA Caucasian Bethesda12.40.0660307See
CHNChina Jiangsu Han0.06603238See
CHNChina Tibet Region Tibetan0.0630158See
VNMVietnam Hanoi Kinh pop 20.0620170See
JPNJapan pop 50.0610117See
USAUSA NMDP Japanese0.060324582See
MYSMalaysia Sarawak Bau Bidayuh0.060025See
ENGEngland North West11.40.0600298See
CUBCuba Mixed Race11.90.060042See
JPNJapan Hokkaido Ainu0.060050See
SGPSingapore Riau Malay0.0590132See
CHNChina Inner Mongolia Region0.0590102See
USAUSA Hawaii Okinawa0.0580106See
DEUGermany DKMS - United Kingdom minority0.05751043See
USAUSA Caucasian11.00.056661655See
CHNChina Southwest Dai0.0560124See
THAThailand Northeast pop 20.0550400See
CHESwitzerland Sion0.0550832See
NIRIreland Northern10.20.05401000See
JPNJapan pop 30.05401018See
JPNJapan pop 160.053518604See
USAUSA NMDP Vietnamese0.053343540See
CHESwitzerland Basel0.05311888See
PNGPapua New Guinea Wanigela Keapara0.053066See
RUSRussia Bering Island Aleuts0.0529104See
USAUSA NMDP European Caucasian0.05281242890See
CHESwitzerland Zurich0.05244875See
CHNChina Guangzhou Han0.0520106See
DEUGermany DKMS - Austria minority0.05181698See
USAUSA NMDP North American Amerindian0.051835791See
DEUGermany DKMS - German donors0.05133456066See
INDIndia Jalpaiguri Toto10.00.051340See
USAUSA San Antonio Caucasian0.0512222See
USAUSA European American pop 20.05101245See
INDIndia Northeast UCBB10.10.0507296See
ESPSpain Gipuzkoa Basque0.0500100See
RUSRussia Tuva pop 20.0500169See
AUSAustralia Yuendumu Aborigine0.0490191See
CHESwitzerland Bern0.04903545See
DEUGermany pop 80.048739689See
DEUGermany pop 60.04788862See
USAUSA NMDP Alaska Native or Aleut0.04601376See
PNGPapua New Guinea West Schrader Ranges Haruai0.046055See
CHNChina Yunnan Province Han0.0450101See
USAUSA NMDP Southeast Asian0.045027978See
RUSRussia Karelia0.04491075See
KORSouth Korea pop 100.04464128See
USAUSA NMDP American Indian South or Central America0.04405926See
CHESwitzerland Graubunden0.0423759See
USAUSA NMDP Korean0.042077584See
JPNJapan Central0.0420371See
USAUSA San Diego8.00.0420496See
CHESwitzerland Lausanne0.0417993See
CHNChina Qinghai Province Hui0.0410110See
USAUSA Philadelphia Caucasian8.10.0410141See
BFABurkina Faso Fulani0.041049See
ISRIsrael Tunisia Jews0.04079070See
DEUGermany DKMS - France minority0.04021406See
SGPSingapore Thai0.0400100See
KORSouth Korea pop 30.0400485See
USAUSA North American Native0.0400187See
USAUSA Arizona Pima0.0390100See
KORSouth Korea pop 80.03807096See
SGPSingapore SGVP. Indian INS0.038086See
IDNIndonesia Java Western7.20.0370236See
CZECzech Republic NMDR0.03685099See
PRTAzores Central Islands0.036059See
MYSMalaysia Kelantan7.10.036028See
MYSMalaysia Peninsular Malay7.20.0358951See
FRAFrance French Bone Marrow Donor Registry0.035642623See
CHESwitzerland Aargau-Solothurn0.03521838See
ESPSpain Andalusia0.035099See
CHESwitzerland St Gallen0.03362113See
MEXMexico Jalisco, Tlajomulco0.033330See
MEXMexico Queretaro, Queretaro city0.033345See
SCOScotland Orkney5.90.033099See
POLPoland DKMS0.032120653See
MEXMexico Campeche Rural0.031947See
JPNJapan Hyogo6.30.031032See
TWNTaiwan Tao6.00.030050See
RUSRussia Murmansk Saomi Mixed0.030070See
USAUSA Arizona Gila River Amerindian0.0300492See
SGPSingapore SGVP Malay MAS0.030089See
MEXMexico Mexico City West0.029933See
MYSMalaysia Peninsular Indian5.90.0295271See
MEXMexico Chihuahua Chihuahua City Pop 25.70.028488See
CHESwitzerland Geneva pop 20.02781267See
MEXMexico Veracruz, Cordoba0.026856See
CHNChina Uyghur HIV negative0.026019See
IRLIreland South5.20.0260250See
BRABrazil Belo Horizonte Caucasian5.30.026095See
MEXMexico Chihuahua Chihuahua City0.0252119See
ESPSpain Andalusia Romani0.025099See
ITAItaly North Pavia0.025081See
USAUSA San Francisco Caucasian0.0250220See
DEUGermany DKMS - Romania minority0.02481234See
MEXMexico Hidalgo Rural0.024781See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,4.80.02454335See
CZECzech Republic0.0240106See
DEUGermany DKMS - Spain minority0.02391107See
DEUGermany DKMS - Greece minority0.02381894See
ISRIsrael USSR Jews0.023445681See
DEUGermany DKMS - Portugal minority0.02341176See
INDIndia Central UCBB4.60.02314204See
IRNIran Gorgan0.023064See
ZMBZambia Lusaka0.023044See
FRAFrance Southeast4.60.0230130See
MEXMexico Mexico City Tlalpan4.50.0227330See
MEXMexico Mexico City Center0.0227152See
INDIndia West UCBB4.50.02275829See
CHESwitzerland Luzern0.02261553See
ISRIsrael Arab pop 20.022212301See
USAUSA NMDP South Asian Indian0.0221185391See
PRTPortugal North0.022046See
INDIndia South UCBB4.30.021211446See
CUBCuba Caucasian4.30.021070See
USAUSA African American Bethesda4.20.0210187See
ZAFSouth Africa Caucasians0.0210102See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02091028See
USAUSA NMDP Middle Eastern or North Coast of Africa0.020670890See
INDIndia East UCBB4.00.02022403See
MYSMalaysia Kedah Baling Kensiu0.020025See
MYSMalaysia Perak Grik Jehai0.020025See
RUSRussia Nenet Mixed0.020055See
RUSRussia Arkhangelsk Pomor0.020063See
PRTPortugal Center0.020050See
INDIndia Tamil Nadu0.01992492See
MEXMexico Sinaloa, Culiacán0.0194103See
DEUGermany DKMS - Croatia minority0.01902057See
USAUSA African American pop 80.0190605See
GEOGeorgia Tibilisi0.0190109See
INDIndia North UCBB3.80.01905849See
DEUGermany DKMS - Turkey minority0.01854856See
MEXMexico Tabasco, Villahermosa0.018382See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0180146See
IRNIran Yazd0.017956See
ITAItaly pop 50.0170975See
MEXMexico Mexico City Mestizo0.0170121See
LKASri Lanka Colombo3.40.0170714See
MYSMalaysia Champa3.50.017029See
IRNIran Kurd pop 20.017060See
USAUSA NMDP Caribean Hispanic0.0170115374See
IRNIran Saqqez-Baneh Kurds0.016760See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
MEXMexico Mexico City Metropolitan Area Rural0.0164150See
INDIndia Delhi pop 23.30.016090See
UGAUganda Kampala0.0160161See
MEXMexico Veracruz Rural0.0157539See
IRNIran Tabriz Azeris0.015597See
USAUSA Hispanic0.0150234See
PNGPapua New Guinea Wosera Abelam0.0150131See
USAUSA NMDP Caribean Indian0.015014339See
MEXMexico Puebla Mestizo0.015099See
SRBSerbia pop 22.90.0150102See
USAUSA NMDP Hispanic South or Central American0.0144146714See
DEUGermany DKMS - Italy minority0.01431159See
MEXMexico Jalisco, Tonala0.014335See
USAUSA NMDP Mexican or Chicano0.0143261235See
ISRIsrael USA Jews0.01416058See
MARMorocco Atlantic Coast Chaouya0.014098See
BRABrazil Mixed0.0140108See
MARMorocco Settat Chaouya2.80.014098See
HRVCroatia pop 40.01394000See
MEXMexico Guerrero state0.0139144See
CHESwitzerland Lugano0.01351169See
USAUSA Hispanic pop 20.01351999See
USAUSA African American pop 40.01332411See
PRTPortugal Azores Terceira Island2.60.0132130See
MYSMalaysia Pahang Semai2.60.013038See
USAUSA South Texas Hispanic0.0130194See
PRTAzores Oriental Islands0.013043See
GEOGeorgia Svaneti Region Svan0.013080See
USAUSA NMDP African American pop 20.0128416581See
MEXMexico Jalisco Rural0.0128585See
MEXMexico Sonora Rural0.0127197See
MEXMexico Hidalgo, Pachuca0.012241See
PRTAzores Terceira Island0.0120130See
MEXMexico Veracruz Xalapa2.40.011984See
MEXMexico Queretaro Rural0.011643See
MEXMexico Veracruz, Poza Rica0.011145See
USAUSA African American pop 30.0110564See
CHLChile Santiago Mixed2.00.010070See
SDNSudan Mixed1.50.0100200See
INDIndia Andhra Pradesh Golla0.0100111See
INDIndia North pop 20.010072See
USAUSA Alaska Yupik0.0100252See
USAUSA African American0.0100252See
PRTPortugal South0.010049See
MEXMexico Coahuila, Torreon0.0100396See
AREUnited Arab Emirates Pop 10.0100570See
COLColombia Bogotá Cord Blood2.00.00991463See
ISRIsrael Iran Jews0.00978153See
USAUSA NMDP Caribean Black0.009733328See
ISRIsrael Morocco Jews0.009736718See
GRCGreece pop 60.0094242See
MEXMexico Oaxaca Rural0.0092485See
MEXMexico Durango Rural0.0092326See
MEXMexico Sinaloa Mestizo0.009056See
ZAFSouth Africa Worcester2.00.0090159See
MEXMexico Jalisco, Zapopan0.0089168See
USAUSA NMDP African0.008728557See
MEXMexico Puebla, Puebla city0.00851994See
MEXMexico Chihuahua Rural0.0084236See
MEXMexico Sinaloa Rural0.0082183See
MEXMexico Mexico City North0.0080751See
INDIndia New Delhi0.008071See
CPVCape Verde Northwestern Islands0.008062See
MEXMexico Tixcacaltuyub Maya0.007567See
MEXMexico Jalisco, Guadalajara city0.00751189See
MEXMexico Michoacan Rural0.0072348See
MEXMexico Puebla Rural0.0072833See
MEXMexico Mexico City Mestizo population0.0070143See
MEXMexico Michoacan, Morelia0.0066150See
MEXMexico Nuevo Leon, Monterrey city0.0066226See
MEXMexico Durango, Durango city0.0065153See
NICNicaragua Managua1.20.0060339See
AREUnited Arab Emirates pop 21.10.0060373See
MEXMexico Veracruz, Veracruz city0.0058171See
MEXMexico San Luis Potosi Rural0.005787See
MEXMexico Zacatecas Rural0.0056266See
ECUEcuador Andes Mixed Ancestry0.0055824See
ISRIsrael Iraq Jews0.005413270See
ARMArmenia combined Regions0.0050100See
ISRIsrael Arab Druze0.0050101See
MEXMexico Zacatecas, Fresnillo0.0048103See
ECUEcuador Mixed Ancestry0.00471173See
MEXMexico Chiapas Rural0.0041121See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MEXMexico Tlaxcala Rural0.0036830See
MEXMexico Sonora, Ciudad Obregón0.0035143See
BRABrazil Puyanawa0.70.0030150See
JORJordan Amman0.0030146See
CMRCameroon Beti0.0030174See
ISRIsrael Poland Jews0.002813871See
MEXMexico Veracruz, Xalapa0.0027187See
ISRIsrael Georgia Jews0.00274471See
ISRIsrael Druze0.00255914See
ISRIsrael Ashkenazi Jews pop 30.00254625See
ISRIsrael Ethiopia Jews0.00245928See
MEXMexico Nuevo Leon Rural0.0023439See
ECUEcuador Coast Mixed Ancestry0.0021238See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
ZWEZimbabwe Harare Shona0.0020230See
ISRIsrael Argentina Jews0.00134307See
ISRIsrael Bukhara Jews0.00082317See
ISRIsrael YemenJews0.000615542See
ISRIsrael Kavkazi Jews0.00052840See
ECUEcuador Amazonia Mixed Ancestry0.000039See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CMRCameroon Bamileke0.000077See
CPVCape Verde Southeastern Islands0.000062See
GNBGuinea Bissau0.000065See
CHNChina North Han0.0000105See
PNGPapua New Guinea Madang0.000065See
ZAFSouth Africa Natal Zulu0.00.0000100See
INDIndia Mumbai Maratha0.000091See
MEXMexico Mestizo0.00.000041See
ITAItaly Bergamo0.00.0000101See
MARMorocco Nador Metalsa pop 20.000073See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MLIMali Bandiagara0.0000138See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nayarit Rural0.000064See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Baja California Rural0.000050See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Mexico City East0.000079See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Aguascalientes state0.000095See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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