Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 378 time(s) and present in 365 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
VENVenezuela Perja Mountain Bari0.398055See
PNGPapua New Guinea Wosera Abelam0.3700131See
USAUSA Alaska Yupik0.2960252See
PNGPapua New Guinea Karimui Plateau Pawaia0.281080See
AUSAustralia Kimberly Aborigine0.276041See
MEXMexico Chiapas Lacandon Mayans0.2638218See
MEXMexico Chichen Itza Maya (prehispanic)0.244747See
TWNTaiwan Tao38.00.230050See
ARGArgentina Gran Chaco Mataco Wichi37.00.217049See
MEXMexico Chihuahua Tarahumara0.205044See
TWNTaiwan Siraya37.30.196051See
AUSAustralia Yuendumu Aborigine0.1890191See
AUSAustralia Groote Eylandt Aborigine0.180075See
ECUEcuador Amazonia Mixed Ancestry0.166739See
MEXMexico Quintana Roo Rural0.160050See
MEXMexico Sonora Seri0.152034See
MEXMexico Campeche, Campeche city0.147134See
PHLPhilippines Ivatan24.00.140050See
BRABrazil Puyanawa24.70.1400150See
TWNTaiwan Paiwan25.50.137051See
MEXMexico Colima Rural0.136443See
MEXMexico San Luis Potosi Rural0.132287See
TWNTaiwan Rukai24.00.130050See
RUSRussia Bering Island Aleuts0.1298104See
PNGPapua New Guinea West Schrader Ranges Haruai0.127055See
MEXMexico Veracruz, Coatzacoalcos0.125055See
MEXMexico Chiapas, Tuxtla Gutierrez0.122652See
MEXMexico Baja California, Tijuana0.120025See
MEXMexico Mexico City East0.118879See
USAUSA NMDP Alaska Native or Aleut0.11601376See
MEXMexico Morelos, Cuernavaca0.115982See
MEXMexico Oaxaca Mixe0.113055See
ARGArgentina Gran Chaco Eastern Toba19.00.1120135See
MEXMexico Sonora, Ciudad Obregón0.1119143See
ARGArgentina Rosario Toba20.90.110086See
MEXMexico Tabasco, Villahermosa0.109882See
MEXMexico Sinaloa Rural0.1093183See
MEXMexico Yucatan Rural0.1082132See
ARGArgentina Gran Chaco Western Toba Pilaga21.40.107019See
MEXMexico Durango, Durango city0.1065153See
MEXMexico Campeche Rural0.106447See
NICNicaragua Managua19.00.1039339See
MEXMexico Tamaulipas Rural0.1032125See
ECUEcuador Andes Mixed Ancestry0.1019824See
MEXMexico Veracruz Xalapa20.20.101284See
USAUSA Arizona Pima0.1010100See
USAUSA South Texas Hispanic0.1000194See
ECUEcuador Mixed Ancestry0.09931173See
MEXMexico Nuevo Leon Rural0.0989439See
MEXMexico Veracruz, Xalapa0.0989187See
MEXMexico Sinaloa, Culiacán0.0971103See
RUSRussia Tuva pop 20.0970169See
MEXMexico Mexico City South0.096252See
USAUSA Hawaii Okinawa0.0960106See
MEXMexico Coahuila, Saltillo0.095972See
MEXMexico Baja Californa, Mexicali0.0950100See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
MEXMexico Baja California, La Paz0.093375See
NZLNew Zealand Polynesians with Admixed History14.80.093027See
MEXMexico Puebla Rural0.0923833See
MEXMexico Sonora, Hermosillo0.090999See
MEXMexico Puebla Mestizo0.090099See
MEXMexico Mexico City West0.089633See
TWNTaiwan Tsou17.60.088051See
MEXMexico Tlaxcala Rural0.0873830See
MEXMexico Durango Rural0.0872326See
MEXMexico Yucatan, Merida0.0872192See
KORSouth Korea pop 80.08707096See
MEXMexico Puebla, Puebla city0.08671994See
MEXMexico Sonora Rural0.0863197See
MEXMexico Coahuila, Torreon0.0863396See
ECUEcuador Coast Mixed Ancestry0.0861238See
MEXMexico Michoacan, Morelia0.0861150See
JPNJapan Central0.0860371See
MEXMexico Hidalgo, Pachuca0.085441See
COLColombia Bogotá Cord Blood15.90.08441463See
SWESweden Northern Sami0.0840154See
MEXMexico San Luis Potosi, San Luis Potosi city0.083330See
JPNJapan pop 30.08301018See
MEXMexico Nayarit, Tepic0.082597See
MEXMexico Tixcacaltuyub Maya0.082167See
AUSAustralia Cape York Peninsula Aborigine0.0800103See
JPNJapan pop 160.079518604See
MEXMexico Jalisco Rural0.0794585See
RUSRussia Nenet Mixed0.079055See
MEXMexico Mexico City Metropolitan Area Rural0.0789150See
MEXMexico Aguascalientes state0.078995See
GTMGuatemala, Guatemala City Mixed Ancestry15.80.0787127See
MEXMexico Nayarit Rural0.078164See
MEXMexico Guadalajara Mestizo pop 20.0780103See
USAUSA Arizona Gila River Amerindian0.0780492See
MEXMexico Queretaro, Queretaro city0.077845See
MEXMexico Tlaxcala, Tlaxcala city0.0773181See
USAUSA NMDP Filipino0.077150614See
USAUSA NMDP Japanese0.076624582See
MEXMexico Nuevo Leon, Monterrey city0.0752226See
TWNTaiwan Taroko12.70.073055See
MEXMexico Michoacan Rural0.0716348See
MEXMexico Jalisco, Zapopan0.0714168See
MEXMexico Chihuahua Rural0.0711236See
CHNChina Guangzhou Han0.0710106See
MEXMexico Baja California Rural0.070050See
MEXMexico Oaxaca Mixtec0.0690103See
CHNChina Inner Mongolia Region0.0690102See
MEXMexico Guanajuato, Guanajuato city0.068222See
MEXMexico Guanajuato Rural0.0675162See
MEXMexico Veracruz, Orizaba0.066760See
MEXMexico Veracruz Rural0.0665539See
MEXMexico Mexico City Mestizo0.0660121See
MEXMexico Zacatecas, Zacatecas city0.065584See
MEXMexico Tamaulipas, Ciudad Victoria0.065223See
MEXMexico Jalisco, Tlaquepaque0.064139See
MEXMexico Jalisco, Guadalajara city0.06371189See
MEXMexico Guerrero state0.0625144See
MEXMexico Mexico City North0.0624751See
MEXMexico Mexico City Tlalpan12.40.0621330See
JPNJapan pop 50.0610117See
RUSRussia Murmansk Saomi Mixed0.060070See
TWNTaiwan Puyuma12.00.060050See
USAUSA North American Native0.0590187See
MEXMexico Queretaro Rural0.058143See
MEXMexico Guanajuato, Leon0.057778See
COLColombia North Wiwa El Encanto0.057752See
MEXMexico Colima, Colima city0.057461See
USAUSA NMDP Mexican or Chicano0.0573261235See
MEXMexico Jalisco, Tonala0.057135See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.057057See
MEXMexico Mexico City Center0.0552152See
MEXMexico Veracruz, Veracruz city0.0552171See
MEXMexico Chihuahua Chihuahua City0.0546119See
MEXMexico Sinaloa Mestizo0.054056See
ISRIsrael Druze0.05375914See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0536233See
MEXMexico Mexico City Mestizo pop 20.0534234See
MEXMexico Oaxaca Rural0.0534485See
TWNTaiwan Ami10.20.051098See
USAUSA Hispanic0.0510234See
MEXMexico Coahuila Rural0.0505216See
MEXMexico Zacatecas Rural0.0502266See
MEXMexico Morelos Rural0.050030See
MEXMexico Jalisco, Tlajomulco0.050030See
ISRIsrael Arab Druze0.0500101See
CHNChina Qinghai Province Hui0.0500110See
MEXMexico Chiapas Rural0.0496121See
USAUSA New Mexico Canoncito Navajo0.049042See
USAUSA Hispanic pop 20.04851999See
USAUSA NMDP Hawaiian or other Pacific Islander0.048211499See
NZLNew Zealand Maori with Admixed History8.60.0480105See
USAUSA NMDP Hispanic South or Central American0.0478146714See
MEXMexico Zacatecas, Fresnillo0.0476103See
USAUSA NMDP Korean0.046777584See
PNGPapua New Guinea Wanigela Keapara0.046066See
CHNChina Beijing0.046067See
MEXMexico Tabasco Rural0.0458142See
MEXMexico Veracruz, Cordoba0.044656See
MEXMexico Veracruz, Poza Rica0.044445See
KORSouth Korea pop 100.04414128See
MEXMexico Hidalgo Rural0.043281See
MEXMexico Oaxaca Jamiltepec Mixtec0.042096See
MEXMexico Chihuahua, Ciudad Juarez0.0417106See
MEXMexico Quintana Roo, Cancun0.041748See
MEXMexico Mixtec0.041097See
CHNChina Guizhou Province Bouyei0.0410109See
CHLChile Santiago Mixed8.00.040870See
AREUnited Arab Emirates pop 27.80.0400373See
PNGPapua New Guinea East New Britain Rabaul0.040060See
MEXMexico Chihuahua Chihuahua City Pop 28.00.039888See
SWESweden Southern Sami0.0390130See
TWNTaiwan Minnan pop 16.90.0390102See
KORSouth Korea pop 30.0380485See
MEXMexico Oaxaca Zapotec0.037090See
MEXMexico Mestizo7.30.037041See
PRTAzores Central Islands0.036059See
MEXMexico Mexico City Mestizo population0.0350143See
PRTPortugal North0.033046See
USAUSA Asian0.0320358See
USAUSA San Diego5.40.0320496See
JPNJapan Hyogo6.30.031032See
FRAFrance Southeast6.20.0310130See
USAUSA NMDP North American Amerindian0.031035791See
USAUSA Asian pop 20.03061772See
USAUSA NMDP Caribean Hispanic0.0301115374See
USAUSA NMDP American Indian South or Central America0.03005926See
JPNJapan Hokkaido Ainu0.030050See
ASMAmerican Samoa0.030051See
RUSRussia Karelia0.02901075See
NCLNew Caledonia0.029065See
CHNChina Sichuan HIV negative0.029034See
CHNChina Guangxi Region Maonan0.0280108See
USAUSA NMDP Caribean Indian0.028014339See
TWNTaiwan Pazeh5.50.027055See
CHNChina Jiangsu Province Han0.0263334See
CHNChina Uyghur HIV negative0.026019See
TWNTaiwan Bunun5.00.0250101See
THAThailand Northeast pop 20.0240400See
CPVCape Verde Northwestern Islands0.024062See
GRCGreece pop 60.0236242See
MEXMexico Oaxaca, Oaxaca city0.0232151See
CHNChina Shanxi HIV negative0.023022See
HRVCroatia pop 40.02284000See
NZLNew Zealand Maori with Full Ancestry4.30.022046See
USAUSA South Dakota Lakota Sioux0.0220302See
DEUGermany DKMS - China minority0.02151282See
DEUGermany DKMS - Croatia minority0.02092057See
CHESwitzerland Graubunden0.0203759See
TWNTaiwan Tzu Chi Morrow Donor Registry0.020346682See
TWNTaiwan pop 20.0200364See
THAThailand pop 30.020049See
CHNChina Jiangsu Han0.02003238See
RUSRussia Arkhangelsk Pomor0.020063See
DEUGermany DKMS - Netherlands minority0.01931374See
ITAItaly North Pavia0.019081See
CHNChina North Han0.0190105See
TWNTaiwan Atayal3.80.0190106See
GRCGreece pop 83.60.018183See
MYSMalaysia Peninsular Chinese3.60.0180194See
PNGPapua New Guinea Madang0.018065See
ITAItaly pop 50.0180975See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01801028See
CHNChina South Han0.0180284See
CHNChina Marrow Donor Registry0.0180600See
TWNTaiwan Hakka3.60.018055See
CHESwitzerland Lausanne0.0179993See
CHNChina Hubei Han3.60.01783732See
POLPoland DKMS0.017720653See
USAUSA NMDP Chinese0.017399672See
SGPSingapore Chinese3.40.0170149See
TWNTaiwan pop 30.0170212See
MYSMalaysia Champa3.50.017029See
BRABrazil Terena3.50.017060See
ISRIsrael Argentina Jews0.01684307See
DEUGermany DKMS - German donors0.01663456066See
BRABrazil Belo Horizonte Caucasian3.20.016095See
UGAUganda Kampala0.0160161See
CHESwitzerland Zurich0.01594875See
DEUGermany DKMS - Romania minority0.01581234See
DEUGermany pop 80.015839689See
CZECzech Republic NMDR0.01565099See
FRAFrance French Bone Marrow Donor Registry0.015242623See
CHESwitzerland Bern0.01513545See
CHNChina Canton Han0.0150264See
DEUGermany DKMS - Greece minority0.01511894See
USAUSA Caucasian pop 20.0150265See
TWNTaiwan Tzu Chi Cord Blood Bank0.0150710See
TWNTaiwan Han Chinese0.0150504See
SRBSerbia pop 22.90.0150102See
SGPSingapore Thai0.0150100See
USAUSA Philadelphia Caucasian3.00.0150141See
DEUGermany DKMS - France minority0.01491406See
HKGHong Kong Chinese BMDR0.01497595See
DEUGermany pop 60.01458862See
DEUGermany DKMS - Spain minority0.01451107See
HKGHong Kong Chinese cord blood registry0.01413892See
MARMorocco Settat Chaouya2.80.014098See
CZECzech Republic0.0140106See
MARMorocco Atlantic Coast Chaouya0.014098See
USAUSA European American pop 20.01401245See
DEUGermany DKMS - Austria minority0.01361698See
DEUGermany DKMS - United Kingdom minority0.01341043See
CHESwitzerland Aargau-Solothurn0.01321838See
PRTPortugal Azores Terceira Island2.60.0132130See
PRTAzores Oriental Islands0.013043See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.60.01304335See
CHESwitzerland Sion0.0127832See
DEUGermany DKMS - Portugal minority0.01281176See
USAUSA NMDP European Caucasian0.01261242890See
ISRIsrael Poland Jews0.012413871See
DEUGermany DKMS - Turkey minority0.01224856See
CUBCuba Mixed Race2.40.012042See
ESPSpain Andalusia0.012099See
PRTAzores Terceira Island0.0120130See
USAUSA Caucasian Bethesda2.40.0120307See
VNMVietnam Hanoi Kinh pop 20.0120170See
CHESwitzerland St Gallen0.01182113See
ISRIsrael Ashkenazi Jews pop 30.01184625See
DEUGermany DKMS - Italy minority0.01171159See
USAUSA Caucasian2.30.011561655See
SGPSingapore SGVP Chinese CHS0.011096See
INDIndia Delhi pop 22.20.011090See
CHNChina Beijing Shijiazhuang Tianjian Han0.0110618See
NLDNetherlands Leiden0.01101305See
TUNTunisia Gabes0.010595See
USAUSA Caucasian pop 40.01021070See
SGPSingapore Javaneses0.010051See
TWNTaiwan Saisiat2.00.010051See
ZAFSouth Africa Caucasians0.0100102See
PERPeru Titikaka Lake Uros0.0100105See
PRTPortugal Center0.010050See
CHNChina Yunnan Hani0.0100150See
USAUSA NMDP Middle Eastern or North Coast of Africa0.009370890See
USAUSA San Antonio Caucasian0.0090222See
USAUSA San Francisco Caucasian0.0090220See
PERPeru Titikaka Lake Uro0.0090105See
IRNIran Yazd0.008956See
CHESwitzerland Basel0.00881888See
CHESwitzerland Geneva pop 20.00871267See
AUSAustralia New South Wales Caucasian0.0080134See
CHNChina Yunnan Province Wa0.0080119See
CPVCape Verde Southeastern Islands0.008062See
IRNIran Gorgan0.008064See
INDIndia New Delhi0.008071See
GNBGuinea Bissau0.008065See
CHLChile Mapuche0.007766See
USAUSA NMDP Vietnamese0.007643540See
CHESwitzerland Luzern0.00751553See
MYSMalaysia Peninsular Malay1.50.0074951See
MYSMalaysia Peninsular Indian1.50.0074271See
CHNChina Guizhou Province Shui0.0070153See
MARMorocco Nador Metalsa pop 20.007073See
USAUSA NMDP Southeast Asian0.006927978See
CHESwitzerland Lugano0.00671169See
CHNChina Guizhou Province Miao pop 20.006085See
SGPSingapore SGVP. Indian INS0.006086See
SGPSingapore SGVP Malay MAS0.006089See
ZAFSouth Africa Worcester1.00.0060159See
ISRIsrael Ethiopia Jews0.00545928See
ENGEngland North West1.00.0050298See
ESPSpain Andalusia Romani0.005099See
INDIndia Andhra Pradesh Golla0.0050111See
HKGHong Kong Chinese1.10.0050569See
CHNChina Yunnan Province Han0.0050101See
CHNChina Guangdong Province Meizhou Han0.0050100See
SGPSingapore Riau Malay0.0050132See
SDNSudan Mixed1.00.0050200See
ISRIsrael Libya Jews0.00453739See
INDIndia North UCBB0.90.00455849See
ISRIsrael Arab pop 20.004112301See
IRLIreland South0.80.0040250See
LKASri Lanka Colombo0.80.0040714See
INDIndia East UCBB0.80.00382403See
ISRIsrael USSR Jews0.003745681See
USAUSA African American pop 40.00352411See
USAUSA NMDP Caribean Black0.003533328See
INDIndia West UCBB0.70.00345829See
USAUSA NMDP African American pop 20.0033416581See
NIRIreland Northern0.60.00301000See
USAUSA NMDP South Asian Indian0.0030185391See
INDIndia Central UCBB0.60.00294204See
USAUSA NMDP African0.002728557See
INDIndia Tamil Nadu0.00252492See
INDIndia South UCBB0.50.002511446See
ISRIsrael Tunisia Jews0.00229070See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
USAUSA African American0.0020252See
USAUSA African American pop 80.0020605See
INDIndia Northeast UCBB0.30.0017296See
ISRIsrael USA Jews0.00176058See
ISRIsrael Iran Jews0.00138153See
ISRIsrael Georgia Jews0.00104471See
ISRIsrael Kavkazi Jews0.00092840See
ISRIsrael YemenJews0.000815542See
ISRIsrael Morocco Jews0.000736718See
ISRIsrael Bukhara Jews0.00022317See
ISRIsrael Iraq Jews0.000213270See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
CUBCuba Caucasian0.00.000070See
CHNChina Guangzhou0.0000102See
CHNChina Yunnan Province Jinuo0.0000109See
SCOScotland Orkney0.00.000099See
PRTPortugal South0.000049See
MLIMali Bandiagara0.0000138See
USAUSA African American Bethesda0.00.0000187See
ZMBZambia Lusaka0.000044See
ZAFSouth Africa Natal Zulu0.00.0000100See
TWNTaiwan Thao0.00.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional