Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 61 time(s) and present in 60 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CRICosta Rica Cabecar NA-DHS_9 (G)78.90.500019See
COLColombia/Brazil Ticuna Tarapaca NA-DHS_22 (G)57.90.447419See
CRICosta Rica Amerindians (G)57.80.3580125See
COLColombia Kogi NA-DHS_17 (G)64.30.321415See
COLColombia Inga NA-DHS_11 (G)42.90.285716See
COLColombia Zenu NA-DHS_18 (G)43.80.250016See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)42.90.250017See
COLColombia Waunana NA-DHS_20 (G)45.00.250020See
COLColombia Wayuu NA-DHS_15 (G)33.30.200015See
CRICosta Rica Guaymi NA-DHS_10 (G)33.30.166718See
MEXMexico Mixe NA-DHS_6 (G)30.00.150020See
CANCanada Chipewyan NA-DHS_2 (G)28.00.140025See
CANCanada Ojibwa NA-DHS_4 (G)26.70.133316See
USAUSA Spain Ancestry0.1080279See
COLColombia Embera NA-DHS_19 (G)21.40.107114See
NICNicaragua Mestizo (G)20.80.1070155See
RUSRussia Tundra Nentsi NA-DHS_1 (G)18.80.093816See
CRICosta Rica Central Valley Mestizo (G)16.30.0930221See
PRYParaguay/Argentina Ache NA-DHS_24 (G)18.20.090913See
MEXMexico Hidalgo Mezquital Valley/ Otomi15.30.083372See
USAUSA Arizona Gila River Pima0.07643000See
MEXMexico Mixtec NA-DHS_5 (G)15.00.075020See
CRICosta Rica Guanacaste Mestizo (G)13.60.0680110See
USAUSA Mexican American Mestizo0.0670553See
COLColombia Arhuaco NA-DHS_16 (G)11.80.058817See
CHNChina Tibet Region Tibetan0.0570158See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)10.00.050010See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
RUSRussia Bashkortostan, Bashkirs7.50.0458120See
CHNChina Yunnan Province Lisu0.0360111See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
BRABrazil Barra Mansa Rio State Caucasian0.0247405See
CHNChina Zhejiang Han0.02451734See
RUSRussia Nizhny Novgorod, Russians4.40.02221510See
RUSRussian Federation Vologda Region4.20.0210119See
ESPSpain, Canary Islands, Gran canaria island3.70.0209215See
GRCGreece Athens4.10.02071888See
BRABrazil Barra Mansa Rio State Black0.020573See
BRABrazil Rio de Janeiro Caucasian0.0202521See
USAUSA Eastern European0.0200558See
ZAFSouth African Mixed ancestry4.00.020050See
RUSRussia Belgorod region3.90.0196153See
RUSRussia Bashkortostan, Tatars3.60.0182192See
POLPoland BMR3.50.017723595See
BRABrazil Rio de Janeiro Parda0.0176170See
BRABrazil Rio de Janeiro Black0.014968See
ENGEngland Blood Donors of Mixed Ethnicity2.70.0135519See
HKGHong Kong Chinese HKBMDR HLA 11 loci2.20.01125266See
USAUSA San Francisco Caucasian0.0090220See
USAUSA Italy Ancestry0.0070273See
INDIndia Kerala Malayalam speaking1.40.0070356See
SAUSaudi Arabia pop 51.30.0063158See
USAUSA African American pop 30.0050564See
VNMVietnam Kinh1.00.0050101See
IDNIndonesia Sundanese and Javanese0.0030201See
SAUSaudi Arabia pop 6 (G)0.003028927See
INDIndia Andhra Pradesh Telugu Speaking0.50.0027186See
IDNIndonesia Java pop 20.000036See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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