Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 179 time(s) and present in 108 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Arizona Gila River Amerindian0.1510492See
USAUSA Arizona Pima0.1460100See
MEXMexico Chihuahua Tarahumara0.114044See
MEXMexico Sonora Seri0.091034See
MEXMexico Mexico City South0.038552See
MEXMexico Nayarit, Tepic0.036197See
MEXMexico Jalisco, Tlajomulco0.033330See
MEXMexico Tabasco, Villahermosa0.030582See
MEXMexico Coahuila Rural0.0298216See
MEXMexico Coahuila, Saltillo0.027472See
MEXMexico Hidalgo Rural0.024781See
MEXMexico Zacatecas, Zacatecas city0.023884See
MEXMexico Mexico City North0.0232751See
MEXMexico Durango, Durango city0.0226153See
MEXMexico Veracruz, Poza Rica0.022245See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
MEXMexico Baja California, Tijuana0.020025See
INDIndia West Coast Parsi0.020050See
MEXMexico Tamaulipas Rural0.0198125See
MEXMexico Zacatecas, Fresnillo0.0190103See
MEXMexico Mexico City East0.018879See
MEXMexico Durango Rural0.0183326See
MEXMexico Veracruz Xalapa3.60.017984See
MEXMexico Veracruz, Cordoba0.017956See
MEXMexico Veracruz, Orizaba0.016760See
MEXMexico Colima, Colima city0.016461See
MEXMexico Mexico City Center0.0162152See
USAUSA Spain Ancestry0.0160279See
MEXMexico Puebla Rural0.0156833See
MEXMexico Mexico City West0.014933See
MEXMexico Michoacan Rural0.0143348See
MEXMexico Chihuahua, Ciudad Juarez0.0139106See
MEXMexico Baja California, La Paz0.013375See
MEXMexico Mexico City Metropolitan Area Rural0.0132150See
MEXMexico Michoacan, Morelia0.0132150See
MEXMexico Chihuahua Chihuahua City0.0126119See
MEXMexico Jalisco, Guadalajara city0.01211189See
MEXMexico Mexico City Mestizo0.0120121See
MEXMexico Mestizo2.40.012041See
MEXMexico San Luis Potosi Rural0.011587See
MEXMexico Coahuila, Torreon0.0113396See
MEXMexico Zacatecas Rural0.0112266See
MEXMexico Queretaro, Queretaro city0.011145See
MEXMexico Tlaxcala, Tlaxcala city0.0111181See
MEXMexico Mexico City Mestizo pop 20.0107234See
MEXMexico Sonora, Ciudad Obregón0.0105143See
MEXMexico Chihuahua Rural0.0105236See
MEXMexico Sonora Rural0.0102197See
MEXMexico Sonora, Hermosillo0.010199See
RUSRussia Arkhangelsk Pomor0.010063See
MEXMexico Jalisco Rural0.0094585See
MEXMexico Nuevo Leon Rural0.0091439See
MEXMexico Sinaloa Mestizo0.009056See
MEXMexico Jalisco, Zapopan0.0089168See
USAUSA NMDP Mexican or Chicano0.0083261235See
MEXMexico Sinaloa Rural0.0082183See
MEXMexico Veracruz, Xalapa0.0080187See
MEXMexico Nayarit Rural0.007864See
MEXMexico Yucatan Rural0.0075132See
MEXMexico Puebla, Puebla city0.00751994See
MEXMexico Tabasco Rural0.0070142See
MEXMexico Morelos, Cuernavaca0.006182See
CHNChina Tibet Region Tibetan0.0060158See
MEXMexico Veracruz, Veracruz city0.0058171See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MEXMexico Veracruz Rural0.0055539See
USAUSA Hispanic pop 20.00551999See
MEXMexico Oaxaca Rural0.0051485See
MEXMexico Yucatan, Merida0.0051192See
MEXMexico Baja Californa, Mexicali0.0050100See
MEXMexico Puebla Mestizo0.005099See
MEXMexico Guadalajara Mestizo pop 20.0050103See
INDIndia Delhi pop 21.10.005090See
CHNChina Qinghai Province Hui0.0050110See
USAUSA Mexican American Mestizo0.0050553See
MEXMexico Sinaloa, Culiacán0.0049103See
PRTPortugal Azores Terceira Island0.90.0044130See
MEXMexico Nuevo Leon, Monterrey city0.0044226See
MEXMexico Chiapas Rural0.0041121See
USAUSA South Texas Hispanic0.0040194See
USAUSA African American0.0040252See
USAUSA Hispanic0.0040234See
PRTAzores Terceira Island0.0040130See
MEXMexico Guerrero state0.0035144See
MEXMexico Mexico City Mestizo population0.0035143See
MEXMexico Guanajuato Rural0.0031162See
USAUSA NMDP North American Amerindian0.003135791See
USAUSA North American Native0.0030187See
MEXMexico Tlaxcala Rural0.0030830See
JORJordan Amman0.0030146See
USAUSA NMDP Hispanic South or Central American0.0021146714See
USAUSA NMDP American Indian South or Central America0.00205926See
MEXMexico Mexico City Tlalpan0.30.0015330See
NICNicaragua Managua0.30.0015339See
ITAItaly pop 50.0010975See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Asian0.0010358See
USAUSA NMDP Hawaiian or other Pacific Islander0.000411499See
USAUSA NMDP Caribean Hispanic0.0002115374See
USAUSA NMDP Japanese0.000124582See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000070890See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP South Asian Indian0.0000185391See
DEUGermany DKMS - German donors0.00003456066See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
ECUEcuador Mixed Ancestry0.00001173See
HKGHong Kong Chinese0.00.0000569See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CZECzech Republic0.0000106See
CHNChina Inner Mongolia Region0.0000102See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CHNChina North Han0.0000105See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Queretaro Rural0.000043See
MEXMexico Colima Rural0.000043See
MEXMexico Morelos Rural0.000030See
MEXMexico Campeche Rural0.000047See
MEXMexico Baja California Rural0.000050See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
PHLPhilippines Ivatan0.00.000050See
RUSRussia Nenet Mixed0.000055See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Quintana Roo, Cancun0.000048See
RUSRussia Murmansk Saomi Mixed0.000070See
SCOScotland Orkney0.00.000099See
SGPSingapore Chinese0.00.0000149See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Aguascalientes state0.000095See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
USAUSA African American pop 40.00002411See
USAUSA Asian pop 20.00001772See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
ZAFSouth Africa Natal Zulu0.00.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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