Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 261 time(s) and present in 218 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SCOScotland Orkney26.50.132099See
NIRIreland Northern24.60.13101000See
IRLIreland South24.80.1260250See
USAUSA San Antonio Caucasian0.1205222See
USAUSA Caucasian pop 20.1170265See
AUSAustralia New South Wales Caucasian0.1090134See
TUNTunisia Gabes0.105295See
SWESweden Southern Sami0.1010130See
ENGEngland North West19.10.1010298See
DEUGermany DKMS - United Kingdom minority0.09791043See
USAUSA NMDP European Caucasian0.09521242890See
MARMorocco Nador Metalsa pop 20.094073See
PRTPortugal South0.092049See
GEOGeorgia Tibilisi Kurd0.086031See
USAUSA Caucasian pop 40.08571070See
USAUSA European American pop 20.08201245See
USAUSA Caucasian Bethesda16.20.0810307See
USAUSA Philadelphia Caucasian16.30.0810141See
DEUGermany pop 60.08068862See
CHESwitzerland Graubunden0.0803759See
DEUGermany DKMS - German donors0.08003456066See
CZECzech Republic0.0800106See
FRAFrance Southeast15.40.0800130See
DEUGermany DKMS - Netherlands minority0.07971374See
MEXMexico Chihuahua Chihuahua City Pop 215.90.079588See
USAUSA San Francisco Caucasian0.0780220See
FRAFrance French Bone Marrow Donor Registry0.077442623See
NLDNetherlands Leiden0.07501305See
USAUSA NMDP North American Amerindian0.074435791See
CHESwitzerland Bern0.07443545See
ISRIsrael Druze0.07385914See
DEUGermany pop 80.073239689See
CHESwitzerland St Gallen0.07252113See
DEUGermany DKMS - France minority0.07221406See
USAUSA NMDP American Indian South or Central America0.07205926See
PRTAzores Central Islands0.071059See
CHLChile Easter Island0.071021See
PRTAzores Terceira Island0.0700130See
CHESwitzerland Sion0.0669832See
PRTPortugal Azores Terceira Island13.20.0658130See
DEUGermany DKMS - Austria minority0.06511698See
DEUGermany DKMS - Spain minority0.06461107See
PRTAzores Oriental Islands0.064043See
ISRIsrael Iraq Jews0.063013270See
RUSRussia Karelia0.06231075See
POLPoland DKMS0.061820653See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,11.80.06084335See
CHESwitzerland Zurich0.06044875See
CHESwitzerland Lausanne0.0594993See
MEXMexico Mexico City Tlalpan11.80.0591330See
HRVCroatia pop 40.05894000See
DEUGermany DKMS - Romania minority0.05791234See
DEUGermany DKMS - Bosnia and Herzegovina minority0.05791028See
DEUGermany DKMS - Croatia minority0.05762057See
CHESwitzerland Aargau-Solothurn0.05751838See
USAUSA NMDP Alaska Native or Aleut0.05701376See
DEUGermany DKMS - Portugal minority0.05701176See
USAUSA NMDP Middle Eastern or North Coast of Africa0.054270890See
SRBSerbia pop 210.80.0540102See
CZECzech Republic NMDR0.05385099See
MEXMexico Veracruz Xalapa10.70.053684See
CHESwitzerland Basel0.05301888See
CHNChina Uyghur HIV negative0.053019See
DEUGermany DKMS - Turkey minority0.05184856See
CHESwitzerland Geneva pop 20.05151267See
IRNIran Tabriz Azeris0.051597See
IRNIran Saqqez-Baneh Kurds0.050060See
ISRIsrael Arab Druze0.0500101See
ARMArmenia combined Regions0.0500100See
CUBCuba Caucasian10.00.050070See
PRTPortugal Center0.050050See
RUSRussia Bering Island Aleuts0.0481104See
USAUSA San Diego9.60.0480496See
GRCGreece pop 60.0472242See
RUSRussia Tuva pop 20.0470169See
DEUGermany DKMS - Italy minority0.04541159See
BGRBulgaria Romani0.045013See
CHESwitzerland Lugano0.04321169See
NZLNew Zealand Maori with Admixed History8.60.0430105See
USAUSA North American Native0.0430187See
DEUGermany DKMS - Greece minority0.04281894See
USAUSA NMDP Caribean Hispanic0.0424115374See
BRABrazil Belo Horizonte Caucasian8.40.042095See
USAUSA NMDP Mexican or Chicano0.0413261235See
USAUSA NMDP Hispanic South or Central American0.0403146714See
CHESwitzerland Luzern0.04031553See
NICNicaragua Managua7.50.0392339See
NLDNetherlands UMCU7.80.039164See
COLColombia Bogotá Cord Blood7.70.03901463See
GEOGeorgia Tibilisi0.0370109See
NZLNew Zealand Polynesians with Admixed History7.40.037027See
GRCGreece pop 87.20.036183See
SWESweden Northern Sami0.0350154See
UGAUganda Kampala0.0340161See
USAUSA Hispanic0.0340234See
MARMorocco Atlantic Coast Chaouya0.034098See
MARMorocco Settat Chaouya6.80.034098See
USAUSA Hispanic pop 20.03331999See
ITAItaly North pop 36.70.033097See
ITAItaly pop 50.0330975See
ITAItaly North Pavia0.031081See
GEOGeorgia Svaneti Region Svan0.031080See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
USAUSA NMDP Caribean Indian0.031014339See
ISRIsrael Arab pop 20.030512301See
CHLChile Santiago Mixed6.00.030470See
CHNChina Beijing0.030067See
STPSao Tome Island Forro0.030066See
BRABrazil Mixed0.0290108See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0280146See
JORJordan Amman0.0280146See
IRNIran Yazd0.026856See
AUSAustralia Cape York Peninsula Aborigine0.0250103See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
CHNChina Shanxi HIV negative0.023022See
NZLNew Zealand Maori with Full Ancestry4.30.022046See
USAUSA African American pop 80.0220605See
USAUSA African American pop 40.02122411See
USAUSA African American Bethesda4.20.0210187See
USAUSA NMDP African American pop 20.0208416581See
USAUSA South Dakota Lakota Sioux0.0200302See
USAUSA African American0.0200252See
ISRIsrael Morocco Jews0.019436718See
INDIndia North pop 20.019072See
USAUSA African American pop 30.0190564See
SDNSudan East Rashaida3.70.018627See
KORSouth Korea pop 100.01774128See
USAUSA NMDP Hawaiian or other Pacific Islander0.017311499See
USAUSA South Texas Hispanic0.0170194See
USAUSA NMDP Korean0.016277584See
IRNIran Gorgan0.016064See
USAUSA NMDP Caribean Black0.015833328See
CHLChile Mapuche0.015466See
CHNChina Inner Mongolia Region0.0150102See
ESPSpain Andalusia Romani0.015099See
INDIndia North UCBB2.80.01395849See
USAUSA NMDP African0.013128557See
ZAFSouth Africa Worcester3.00.0130159See
PNGPapua New Guinea East New Britain Rabaul0.013060See
KORSouth Korea pop 30.0120485See
CUBCuba Mixed Race2.40.012042See
ISRIsrael USSR Jews0.011245681See
INDIndia Delhi pop 21.10.011090See
CMRCameroon Beti0.0110174See
MEXMexico Mexico City Mestizo pop 20.0107234See
CHNChina Jiangsu Province Han0.0105334See
AREUnited Arab Emirates Abu Dhabi0.009652See
DEUGermany DKMS - China minority0.00941282See
CHNChina Beijing Shijiazhuang Tianjian Han0.0090618See
USAUSA NMDP Southeast Asian0.008527978See
ISRIsrael Kavkazi Jews0.00832840See
ISRIsrael Poland Jews0.008313871See
INDIndia Central UCBB1.60.00824204See
USAUSA NMDP South Asian Indian0.0082185391See
SDNSudan Mixed1.50.0080200See
USAUSA Alaska Yupik0.0080252See
INDIndia New Delhi0.008071See
GNBGuinea Bissau0.008065See
AREUnited Arab Emirates Pop 10.0080570See
CPVCape Verde Southeastern Islands0.008062See
ISRIsrael YemenJews0.007815542See
USAUSA Asian pop 20.00761772See
USAUSA NMDP Japanese0.007524582See
INDIndia West UCBB1.40.00725829See
ISRIsrael Tunisia Jews0.00719070See
ISRIsrael Ashkenazi Jews pop 30.00704625See
MEXMexico Mexico City Mestizo population0.0070143See
AUSAustralia Groote Eylandt Aborigine0.007075See
CHNChina Jiangsu Han0.00703238See
USAUSA Asian0.0070358See
ISRIsrael Iran Jews0.00638153See
USAUSA Arizona Pima0.0060100See
SGPSingapore SGVP. Indian INS0.006086See
INDIndia South UCBB1.20.005911446See
ISRIsrael Libya Jews0.00583739See
ISRIsrael USA Jews0.00576058See
CHNChina Hubei Han1.10.00563732See
USAUSA NMDP Filipino0.005450614See
ISRIsrael Argentina Jews0.00504307See
CHNChina Marrow Donor Registry0.0050600See
INDIndia East UCBB1.00.00502403See
ISRIsrael Georgia Jews0.00424471See
JPNJapan Central0.0040371See
JPNJapan pop 160.003818604See
USAUSA NMDP Chinese0.003899672See
INDIndia Tamil Nadu0.00352492See
INDIndia Northeast UCBB0.70.0034296See
ISRIsrael Ethiopia Jews0.00345928See
LKASri Lanka Colombo0.60.0030714See
JPNJapan pop 30.00301018See
CHNChina Tibet Region Tibetan0.0030158See
AUSAustralia Yuendumu Aborigine0.0030191See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002546682See
MEXMexico Chiapas Lacandon Mayans0.0023218See
HKGHong Kong Chinese cord blood registry0.00223892See
HKGHong Kong Chinese BMDR0.00217595See
HKGHong Kong Chinese0.40.0020569See
TWNTaiwan Tzu Chi Cord Blood Bank0.0020710See
TWNTaiwan Han Chinese0.0020504See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
MYSMalaysia Peninsular Indian0.40.0018271See
USAUSA NMDP Vietnamese0.001543540See
ISRIsrael Bukhara Jews0.00122317See
TWNTaiwan pop 20.0010364See
MYSMalaysia Peninsular Malay0.10.0005951See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PRTPortugal North0.000046See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
STPSao Tome Island Angolar0.000032See
SGPSingapore SGVP Malay MAS0.000089See
SGPSingapore Chinese0.00.0000149See
SGPSingapore SGVP Chinese CHS0.000096See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See
NCLNew Caledonia0.000065See
MLIMali Bandiagara0.0000138See
KENKenya Nandi0.0000240See
KENKenya Luo0.0000265See
MEXMexico Mestizo0.00.000041See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
CMRCameroon Bamileke0.000077See
CHNChina Guangzhou0.0000102See
CHNChina North Han0.0000105See
CHNChina Qinghai Province Hui0.0000110See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CPVCape Verde Northwestern Islands0.000062See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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